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| 1 | Molecular Characterization of Avian-like H1N1 Swine Influenza A Viruses Isolated in Eastern China, 2011显示文摘Currently, three predominant subtypes of influenza virus are prevalent in pig populations worldwide: H1N1, H3N2, and H1N2. European avian-like H1N1 viruses, which were initially detected in European pig populations in 1979, have been circulating in pigs in eastern China since 2007. In this study, six influenza A viruses were isolated from 60 swine lung samples collected from January to April 2011 in eastern China. Based on whole genome sequencing, molecular characteristics of two isolates were determined. Phylogenetic analysis showed the eight genes of the two isolates were closely related to those of the avian-like H1N1 viruses circulating in pig populations, especially similar to those found in China. Four potential glycosylation sites were observed at positions 13, 26, 198, 277 in the HA1 proteins of the two isolates. Due to the presence of a stop codon at codon 12, the isolates contained truncated PB1-F2 proteins. In this study, the isolates contained 591Q, 627E and 701N in the polymerase subunit PB2, which had been shown to be determinants of virulence and host adaptation. The isolates also had a D rather than E at position 92 of the NS1, a marker of mammalian adaptation. Both isolates contained the GPKV motif at the PDZ ligand domain of the 3' end of the NS1, a characteristic marker of the European avian-like swine viruses since about 1999, which is distinct from those of avian, human and classical swine viruses. The M2 proteins of the isolates have the mutation (S31N), a characteristic marker of the European avian-like swine viruses since about 1987, which may confer resistance to amantadine and rimantadine antivirals. Our findings further emphasize the importance of surveillance on the genetic diversity of influenza A viruses in pigs, and raise more concerns about the occurrence of cross-species transmission events. | Xian Qi Yuning Pan Yuanfang Qin Rongqiang Zu Fengyang Tang Minghao Zhou Hua Wang Yongchun Song | 2012 | Virologica Sinica2012，27，5： | 6 |
| 2 | Assembly of carbon nanodots in graphene-based composite for flexible electro-thermal heater with ultrahigh efficiency显示文摘A high-efficiency electro-thermal heater requires simultaneously high electrical and thermal conductivities to generate and dissipate Joule heat efficiently.A low in put voltage is essential to en sure the heaters safe applications.However,the low voltage gen erally leads to low saturated temperature and heati ng rate and hence a low thermal efficie ncy.How to reduce the in put voltage while maintai ning a high electro-thermal efficiency is still a challenge.Herein,a highly electrical and thermal conductive film was 8nstructed using a graphene-based composite which has an internal three-dimensional(3D)conductive network.In the 3D framework,cellulose nanocrystalline(CNC)phase with chiral liquid crystal manner presents in the form of alig ned helix betwee n the graphe ne oxide(GO)layers.Carbon nano dots(CDs)are assembled泊side the composite as con ductive nano fillers.Subseque nt an neali ng and compressi on results in the formati on of the assembled GO-CNC-CDs film.The carb on ized CNC nano rods(CNR)with the helical alignment act as irrplane and through-pla ne conn ecti ons of n eighbori ng reduced GO(rGO)nano sheets,forming a con ductive network in the composite film.The CDs with ultrafast electr ons tran sfer rates provide additi onal electro ns and phonons tran sport paths for the composite.As a result,the obtai ned graphe ne?based composite film(rGO-CNR-CDs)exhibited a high thermal conductivity of 1,978.6 W m^-1·K^-1 and electrical conductivity of 2,053.4 S·cm^-1,respectively.The composite film showed an outstanding electro-thermal heating efficiency with the saturated temperature of 315℃and maximum heating rate of 44.9℃·s^-1 at a very low in put voltage of 10 V.The freestandi ng graphe ne composite film with the delicate nano structure desig n has a great pote ntial to be integrated into electro-thermal devices. | Xin Meng Tianxing Chen Yao Li Siyuan Liu Hui Pan Yuning Ma Zhixin Chen Yanping Zhang Shenmin Zhu | 2019 | Nano Research2019，12，10： | 3 |
| 3 | Ionic-liquid-assisted growth of flower-like TiO 2 film on Ti substrate with high photocatalytic activity显示文摘 | Hu Li Jia Zhang Xiaofang Chen Gaifang Pan Yuning Huo | 2013 | Journal of Molecular Catalysis A Chemical2013，，： | 1 |
| 4 | School-Based Curriculum Development From the Perspective of Core Literacy-Take Liangzhu Culture as an Example显示文摘With the advancement of the new curriculum reform,school-based curriculum has been practiced in many places.The selection,development,and implementation of the content of school-based curriculum have been widely concerned by the education sector.In this context,this paper is intent to explore the value of school-based curriculum through theoretical research and field investigation,taking Liangzhu culture as the starting point,which also analyzes the principles of school-based curriculum development,including teacher led,focusing on practical exploration,and so on,hoping to be committed to the development of school-based curriculum and promote the cultivation of students’core literacy. | Yuning Jiang Li Zhou Mingfu Pan | 2021 | US-China Education Review(B)2021，11，2： | 0 |
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