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2篇 您的检索式:作者名="Yuling Luan"
    题名 作者 年代 出处 被引量
1Mesenchymal stem cells therapy for acute liver failure: Recent advances and future perspectives显示文摘Acute liver failure(ALF)is a life-threatening disease characterized by the rapid development of hepatocyte death and a systemic inflammatory response,which leads to high mortality.Despite the prevention of ALF complications,therapeutic effectiveness remains limited because of the rapid disease progression.Thus,there is a need to explore various therapeutic approaches.Currently,the only effective treatment is liver transplantation;However,the lack of donors,surgical complications,immunosuppression,and high medical costs limit its clinical application.Recently,mesenchymal stem cells(MSCs)have been found to exert hepatoprotective effects in ALF through suppression of inflammation,immunoregulation,promotion of mitosis,anti-apoptosis effects,and alleviation of the metabolic and oxidative stress imbalance.In this review,we summarize the advantages and disadvantages of MSCs from different sources and their molecular mechanisms in ALF treatment,along with future perspectives that may provide guidance to improve the current status of MSCs therapy for ALF.Yuling Luan Xiaoni Kong Yu Feng 2021Liver Research2021,5,2:3
2Incorporation of Lysine-Containing Copolymer with Polyurethane Affording Biomaterial with Specific Adsorption of Plasminogen显示文摘新奇 biomaterial 通过包含离氨酸的共聚物的物理加入基于聚氨酯(PU ) 被准备改进它的 hemocompatibility 和 plasminogen 的表面识别。包含离氨酸的共聚物经由 2-ethylhexyl methacrylate ( EHMA )的 copolymerization 被综合, oligo (乙烯乙二醇)甲基醚 methacrylate ( OEGMA )和 6-tert-butoxycarbonyl amino-2-( 2-methyl-acryloylamino ) -hexanoic 酸tert丁基酉旨( Lys (P)麻省),在共聚物在离氨酸残余上由 COOH 和 -NH2 组的 deprotection 列在后面。共聚物的作文能被改变单体调整喂比率。三个部件贡献分别地与 PU,到 nonspecific 蛋白质吸附的抵抗和 plasminogen 的特定的绑定改进相容性。向 plasminogen 的有约束力的能力在共聚物与离氨酸内容增加了。这条途径与改进 hemocompatibility 和特定的 biomolecules 的表面识别为新奇 biomaterials 的产生说明一个简单方法。Haichao Xu Yafei Luan Zhaoqiang Wu Xinming Li Yuling Yuan Xiaoli Liu Lin Yuan Dan Li Hong Chen 2014Chinese Journal of Chemistry2014,32,1:1
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