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| 1 | Internet of Things to network smart devices for ecosystem monitoring显示文摘Smart, real-time, low-cost, and distributed ecosystem monitoring is essential for understanding and managing rapidly changing ecosystems. However, new techniques in the big data era have rarely been introduced into operational ecosystem monitoring, particularly for fragile ecosystems in remote areas.We introduce the Internet of Things(IoT) techniques to establish a prototype ecosystem monitoring system by developing innovative smart devices and using IoT technologies for ecosystem monitoring in isolated environments. The developed smart devices include four categories: large-scale and nonintrusive instruments to measure evapotranspiration and soil moisture, in situ observing systems for CO2 and d13 C associated with soil respiration, portable and distributed devices for monitoring vegetation variables, and Bi-CMOS cameras and pressure trigger sensors for terrestrial vertebrate monitoring. These new devices outperform conventional devices and are connected to each other via wireless communication networks. The breakthroughs in the ecosystem monitoring IoT include new data loggers and longdistance wireless sensor network technology that supports the rapid transmission of data from devices to wireless networks. The applicability of this ecosystem monitoring IoT is verified in three fragile ecosystems, including a karst rocky desertification area, the National Park for Amur Tigers, and the oasis-desert ecotone in China. By integrating these devices and technologies with an ecosystem monitoring information system, a seamless data acquisition, transmission, processing, and application IoT is created. The establishment of this ecosystem monitoring IoT will serve as a new paradigm for ecosystem monitoring and therefore provide a platform for ecosystem management and decision making in the era of big data. | Xin Li Ning Zhao Rui Jin Shaomin Liu Xiaomin Sun Xuefa Wen Dongxiu Wu Yan Zhou Jianwen Guo Shiping Chen Ziwei Xu Mingguo Ma Tianming Wang Yonghua Qu Xinwei Wang Fangming Wu Yuke Zhou | 2019 | Science Bulletin2019，64，17： | 10 |
| 2 | An H3K27me3 demethylase-HSFA2 regulatory loop orchestrates transgenerational thermomemory in Arabidopsis显示文摘Global warming has profound effects on plant growth and fitness.Plants have evolved sophisticated epigenetic machinery to respond quickly to heat,and exhibit transgenerational memory of the heat-induced release of post-transtriptional gene silencing(PTGS).However,how thermomemory is transmitted to progeny and the physiological relevance are elusive.Here we show that heat-induced HEAT SHOCK TRANSCRIPTION FACTOR A2(HSFA2)directly activates the H3K27me3 demethylase RELATIVE OF EARLY FLOWERING 6(REF6),which in turn derepresses HSFA2.REF6 and HSFA2 establish a heritable feedback loop,and activate an E3 ubiquitin ligase,SUPPRESSOR OF GENE SILENCING 3(SGS3)-INTERACTING PROTEIN 1(SGIP1).SGIP1-mediated SGS3 degradation leads to inhibited biosynthesis of trans-acting siRNA(tasiRNA).The REF&HSFA2 loop and reduced tasiRNA converge to release HEAT-INDUCED TAS1 TARGET 5(HTT5),which drives early flowering but attenuates immunity.Thus,heat induces transmitted phe no types via a coordi nated epigenetic network involvi ng histone demethylases,tran scriptio n factors,and tasiRNAs,ensuring reproductive success and transgenerational stress adaptation. | Junzhong Liu Lili Feng Xueting Gu Xian Deng Qi Qiu Qun Li Yingying Zhang Muyang Wang Yiwen Deng Ertao Wang Yuke He Isabel Baurle Jianming Li Xiaofeng Cao Zuhua He | 2019 | Cell Research2019，29，5： | 10 |
| 3 | Characteristics of microbial community involved in early biofilms formation under the influence of wastewater treatment plant effluent显示文摘Effluents from wastewater treatment plants(WWTPs) containing microorganisms and residual nutrients can influence the biofilm formation. Although the process and mechanism of bacterial biofilm formation have been well characterized, little is known about the characteristics and interaction of bacteria, archaea and eukaryotes in the early colonization, especially under the influence of WWTP effluent. The aim of this study was to characterize the important bacterial, archaeal and eukaryotic species in the early stage of biofilm formation downstream of the WWTP outlet. Water and biofilm samples were collected 24 and 48 hr after the deposition of bio-cords in the stream. Illumina Miseq sequencing of the 16 S and 18 S rDNA showed that, among the three domains, the bacterial biofilm community had the largest alpha and beta diversity. The early bacterial colonizers appeared to be 'biofilm-specific', with only a few dominant operational taxonomic units(OTUs) shared between the biofilm and the ambient water environment. Alpha-proteobacteria and Ciliophora tended to dominate the bacterial and eukaryotic communities, respectively, of the early biofilm already at 24 hr, whereas archaea played only a minor role during the early stage of colonization. The network analysis showed that the three domains of microbial community connected highly during the early colonization and it might be a characteristic of the microbial communities in the biofilm formation process where co-occurrence relationships could drive coexistence and diversity maintenance within the microbial communities. | Yuke Peng Jie Li Junling Lu Lin Xiao Liuyan Yang | 2018 | Journal of Environmental Sciences2018，30，4： | 6 |
| 4 | New Insights into the Late Triassic Nadigangri Formation of Northern Qiangtang, Tibet, China: Constraints from U-Pb Ages and Hf Isotopes of Detrital and Magmatic Zircons显示文摘We report here U-Pb age and in situ Hf isotopic results for detrital and magmatic zircons from one conglomerate and four tuffite samples from the Late Triassic Nadigangri Formation across the North Qiangtang depression, Tibet. Coupled with previously published data in the region, this paper proposes new insights into the geochronological framework for the Nadigangri Formation. The deposition ages of tuffite from top to bottom in the Woruo Mountain, Quem Co and Dongqu River, are 203 Ma, 226 Ma, 221.5 Ma and 221.1 Ma, respectively. The detrital zircons yield a younger cluster of ages of 201.5–225 Ma from the conglomerate of the Quem Co Formation. The Late Triassic Nadigangri Formation defines a temporal range approximately between 201 and 225 Ma(Norian-Rhaetian), including three predominant groups of 220–225 Ma, 210–217 Ma and 201–205 Ma, which correspond with the three main rifting episodes of initial rifting, further rifting and final rifting. Positive εHf(t) value and low model ages in younger detrital zircons suggests a juvenile character. However, the Hf isotopes of magmatic zircons display the presence of reworked ancient crust with 1.1–1.8 Ga. These results provide strong constraints not only on the temporal range of the Late Triassic Nadigangri Formation, but also on the onset of the Qiangtang Mesozoic rift basin. | LI Xueren WANG Jian CHENG Leli FU Xiugen WANG Yuke | 2018 | Acta Geologica Sinica(English Edition)2018，92，4： | 5 |
| 5 | Effects of Neo-Tethyan evolution on the petroleum system of Persian Gulf Superbasin显示文摘Considering the Neo-Tethyan tectonic process and the resulting environmental changes,a geodynamic model of“one-way train loading”is proposed to analyze the formation and evolution mechanism of the Persian Gulf Superbasin with the most abundant hydrocarbons in the world.The Persian Gulf Superbasin has long been in a passive continental margin setting since the Late Paleozoic in the process of unidirectional subduction,forming a superior regional space of hydrocarbon accu-mulation.During the Jurassic-Cretaceous,the Persian Gulf Superbasin drifted slowly at low latitudes,and developed multiple superimposed source-reservoir-caprock assemblages as a combined result of several global geological events such as the Hadley Cell,the Equatorial Upwelling Current,and the Jurassic True Polar Wander.The collision during the evolution of the foreland basin since the Cenozoic led to weak destruction,which was conducive to the preservation of oil and gas.Accordingly,it is be-lieved that the slow drifting and long retention in favorable climate zone of the continent are the critical factors for hydrocarbon enrichment.Moreover,the prospects of hydrocarbon potential in other continents in the Neo-Tethyan were proposed. | ZHU Rixiang ZHANG Shuichang WAN Bo ZHANG Wang LI Yong WANG Huajian LUO Beiwei LIU Yuke HE Zhiliang JIN Zhijun | 2023 | Petroleum Exploration and Development2023，50，1： | 4 |
| 6 | High-entropy perovskite RETa_(3)O_(9) ceramics for high-temperature environmental/thermal barrier coatings显示文摘Four high-entropy perovskite(HEP)RETa_(3)O_(9) samples were fabricated via a spark plasma sintering(SPS)method,and the corresponding thermophysical properties and underlying mechanisms were investigated for environmental/thermal barrier coating(E/TBC)applications.The prepared samples maintained low thermal conductivity(1.50 W·m^(−1)·K^(−1)),high hardness(10 GPa),and an appropriate Young’s modulus(180 GPa),while the fracture toughness increased to 2.5 MPa·m^(1/2).Nanoindentation results showed the HEP ceramics had excellent mechanical properties and good component homogeneity.We analysed the influence of different parameters(the disorder parameters of the electronegativity,ionic radius,and atomic mass,as well as the tolerance factor)of A-site atoms on the thermal conductivity.Enhanced thermal expansion coefficients,combined with a high melting point and extraordinary phase stability,expanded the applications of the HEP RETa_(3)O_(9).The results of this study had motivated a follow-up study on tantalate high-entropy ceramics with desirable properties. | Lin CHEN Baihui LI Jun GUO Yuke ZHU Jing FENG | 2022 | Journal of Advanced Ceramics2022，11，4： | 4 |
| 7 | Hierarchical Carbon Microtube@Nanotube Core-Shell Structure for High-Performance Oxygen Electrocatalysis and Zn-Air Battery显示文摘Zinc-air batteries(ZABs)hold tremendous promise for clean and efficient energy storage with the merits of high theoretical energy density and environmental friendliness.However,the performance of practical ZABs is still unsatisfactory because of the inevitably decreased activity of electrocatalysts when assembly into a thick electrode with high mass loading.Herein,we report a hierarchical electrocatalyst based on carbon microtube@nanotube core-shell nanostructure(CMT@CNT),which demonstrates superior electrocatalytic activity for oxygen reduction reaction and oxygen evolution reaction with a small potential gap of 0.678 V.Remarkably,when being employed as air-cathode in ZAB,the CMT@CNT presents an excellent performance with a high power density(160.6 mW cm^−2),specific capacity(781.7 mAhgZn^−1)as well as long cycle stability(117 h,351 cycles).Moreover,the ZAB performance of CMT@CNT is maintained well even under high mass loading(3 mg cm−2,three times as much as traditional usage),which could afford high power density and energy density for advanced electronic equipment.We believe that this work is promising for the rational design of hierarchical structured electrocatalysts for advanced metal-air batteries. | Wenfu Xie Jianming Li Yuke Song Shijin Li Jianbo Li Mingfei Shao | 2020 | Nano-Micro Letters2020，12，8： | 3 |
| 8 | Self-Sensing Test Method for the Temperature of Piezoelectric Stacks显示文摘A self-sensing test method for the temperature of piezoelectric stack,based on the high correlation between the static capacitance and the stack temperature,is proposed in order to construct a self-sufficient methodology of temperature measurement. Firstly,a theoretical model of static capacitance of the piezoelectric stack under preload was set up,and the influence of preload on the static capacitance was analyzed. Secondly,the correctness of the model was verified by static capacitance test experiments under various preloading conditions. Finally, the temperature measurement experiments at low-temperature stage for two kinds of piezoelectric stacks,namely the lowtemperature-resistant piezoelectric stack and conventional piezoelectric stack, were conducted under various preloading conditions using a polynomial fitting method. The results,which validate the accuracy of the test method,show that the maximum temperature deviations of the two kinds of piezoelectric stack are 3.9 ℃ and 2.8 ℃,respectively,when the preload force is close to the specified value. The test method uses the piezoelectric stack itself as a temperature sensor,which does not require additional equipment for temperature sensing,so that the space and equipment cost could be economized. And the test for static capacitance is concise and convenient,which indicates that in the cooling process,a concise and efficient test of the temperature of the piezoelectric stack could be realized so as to grasp the current temperature change in time. | SHEN Xing LI Yang LIANG Lei ZHANG Lei DAI Yuke CHEN Yuchen YANG Jinchuan | 2019 | Transactions of Nanjing University of Aeronautics and Astronautics2019，36，1： | 2 |
| 9 | Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis显示文摘RNAs are involved in the crucial processes of disease progression and have emerged as powerful therapeutic targets and diagnostic biomarkers.However,efficient delivery of therapeutic RNA to the targeted location and precise detection of RNA markers remains challenging.Recently,more and more attention has been paid to applying nucleic acid nanoassemblies in diagnosing and treating.Due to the flexibility and deformability of nucleic acids,the nanoassemblies could be fabricated with different shapes and structures.With hybridization,nucleic acid nanoassemblies,including DNA and RNA nanostructures,can be applied to enhance RNA therapeutics and diagnosis.This review briefly introduces the construction and properties of different nucleic acid nanoassemblies and their applications for RNA therapy and diagnosis and makes further prospects for their development. | Mengnan Zhao Rujing Wang Kunmeng Yang Yuhong Jiang Yachen Peng Yuke Li Zhen Zhang Jianxun Ding Sanjun Shi | 2023 | Acta Pharmaceutica Sinica B2023，13，3： | 2 |
| 10 | Alternatively spliced BobCAL transcripts alter curd morphotypes in a collection of Chinese cauliflower accessions显示文摘The curd of cauliflower(Brassica oleracea L.var.botrytis)is a modified inflorescence that is consumed as a vegetable.Curd formation is proposed to be due to a mutation in the BobCAULIFLOWER(BobCAL)gene,but the genetic relationship between BobCAL variation and curd morphotypes remains obscure.To address this question,we collected and classified a collection of 78 cauliflower accessions into four subpopulations according to curd surface features:smooth,coarse,granular,and hairy curd morphotypes.Through the cDNA sequencing of BobCAL alleles,we showed that smooth and coarse accessions characterized by inflorescence meristem arrest presented a strong association with the 451T SNP(BobCAL_T),whereas granular and hairy accessions marked with floral organ arrest presented an association with 451G(BobCAL_G).Interestingly,all BobCAL alleles were alternatively spliced,resulting in a total of four alternative splice(AS)variants due to the retention of the fourth and/or seventh introns.Among accessions with BobCAL_G alleles,the total expression of all these AS variants in granular plants was almost equal to that in hairy plants;however,the expression of the individual AS variants encoding intact proteins relative to those encoding truncated proteins differed.Hairy accessions showed relatively high expression of the individual variants encoding intact proteins,whereas granular accessions displayed relatively low expression.In smooth cauliflower,the overexpression of the BobCAL_Ga variant caused an alteration in the curd morphotype from smooth to hairy,concurrent with an increase in the expression levels of downstream floral identity genes.These results reveal that alternative splicing of BobCAL transcripts is involved in the determination of cauliflower curd morphotypes. | Wenguang Cao Biting Cao Xuan Wang Jinjuan Bai Yong-Zhen Xu Jianjun Zhao Xiaorong Li Yuke He Shengwu Hu | 2020 | Horticulture Research2020，7，1： | 2 |
| 11 | A Two-Phase Paradigm for Joint Entity-Relation Extraction显示文摘An exhaustive study has been conducted to investigate span-based models for the joint entity and relation extraction task.However,these models sample a large number of negative entities and negative relations during the model training,which are essential but result in grossly imbalanced data distributions and in turn cause suboptimal model performance.In order to address the above issues,we propose a two-phase paradigm for the span-based joint entity and relation extraction,which involves classifying the entities and relations in the first phase,and predicting the types of these entities and relations in the second phase.The two-phase paradigm enables our model to significantly reduce the data distribution gap,including the gap between negative entities and other entities,aswell as the gap between negative relations and other relations.In addition,we make the first attempt at combining entity type and entity distance as global features,which has proven effective,especially for the relation extraction.Experimental results on several datasets demonstrate that the span-based joint extraction model augmented with the two-phase paradigm and the global features consistently outperforms previous state-ofthe-art span-based models for the joint extraction task,establishing a new standard benchmark.Qualitative and quantitative analyses further validate the effectiveness the proposed paradigm and the global features. | Bin Ji Hao Xu Jie Yu Shasha Li JunMa Yuke Ji Huijun Liu | 2023 | Computers, Materials & Continua2023，，1： | 1 |
| 12 | BcpLH organizes a specific subset of microRNAs to form a leafy head in Chinese cabbage(Brassica rapa ssp.pekinensis)显示文摘HYL1(HYPONASTIC LEAVES 1)in Arabidopsis thaliana encodes a double-stranded RNA-binding protein needed for proper miRNA maturation,and its null mutant hyl1 shows a typical leaf-incurvature phenotype.In Chinese cabbage,BcpLH(Brassica rapa ssp.pekinensis LEAFY HEADS),a close homolog of HYL1,is differentially expressed in juvenile leaves,which are flat,and in adult leaves,which display extreme incurvature.BcpLH lacks protein–protein interaction domains and is much shorter than HYL1.To test whether BcpLH is associated with defects in microRNA(miRNA)biogenesis and leaf flatness,we enhanced and repressed the activity of BcpLH by transgenics and investigated BcpLH-dependent miRNAs and plant morphology.BcpLH promoted miRNA biogenesis by the proper processing of primary miRNAs.BcpLH downregulation via antisense decreased a specific subset of miRNAs and increased the activities of their target genes,causing upward curvature of rosette leaves and early leaf incurvature,concurrent with the enlargement,earliness,and round-to-oval shape transition of leafy heads.Moreover,BcpLH-dependent miRNAs in Chinese cabbage are not the same as HYL1-dependent miRNAs in Arabidopsis.We suggest that BcpLH controls a specific subset of miRNAs in Chinese cabbage and coordinates the direction,extent,and timing of leaf curvature during head formation in Brassica rapa. | Wenqing Ren Feijie Wu Jinjuan Bai Xiaorong Li Xi Yang Wanxin Xue Heng Liu Yuke He | 2020 | Horticulture Research2020，7，1： | 1 |
| 13 | PRMT6 physically associates with nuclear factor Y to regulate photoperiodic flowering in Arabidopsis显示文摘The timing of floral transition is critical for reproductive success in flowering plants.In long-day(LD)plant Arabidopsis,the floral regulator gene FLOWERING LOCUS T(FT)is a major component of the mobile florigen.FT expression is rhythmically activated by CONSTANS(CO),and specifically accumu-lated at dusk of LDs.However;the underlying mechanism of adequate regulation of FT transcription in response to day-length cues to warrant flowering time still remains to be investigated.Here,we identify a homolog of human protein arginine methyltransferases 6(HsPRMT6)in Arabidopsis,and confirm AtPRMT6 physically interacts with three positive regulators of flowering Nuclear Factors YC3(NF-YC3),NF-YC9,and NF-YB3.Further investigations find that AtPRMT6 and its encoding protein accumulate at dusk of LDs.PRMT6-mediated H3 R2me2a modification enhances the promotion of NF-YCs on FT transcription in response to inductive LD signals.Moreover,AtPRMT6 and its homologues proteins AtPRMT4a and AtPRMT4b coordinately inhibit the expression of FLOWERING LOCUS C,a suppressor of FT.Taken together,our study reveals the role of arginine methylation in photoperiodic pathway and how the PRMT6-mediating H3R2me2a system interacts with NF-CO module to dynamically control FT expression and facilitate flowering time. | Pingxian Zhang Xiulan Li Yifan Wang Weijun Guo Sadaruddin Chachar Adeel Riaz Yuke Geng Xiaofeng Gu Liwen Yang | 2021 | aBIOTECH2021，2，4： | 1 |
| 14 | Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence显示文摘Deregulated telomere length is a causative factor in many physiological and pathological processes,including aging and cancer.Many studies focusing on telomeres have revealed important roles for cooperation between the Shelterin protein complex and telomerase in maintaining telomere length.However,it remains largely unknown whether and how aging-related stresses,such as deregulated protein homeostasis,impact telomere length.Here,we explored the possible roles of aminoacyl tRNA synthetases(AARSs),key enzymes catalyzing the first reactions in protein synthesis,in regulating telomere length and aging.We selected seryl tRNA synthetase(SerRS)since our previous studies discovered expanded functions of SerRS in the nucleus in addition to its canonical cytoplasmic role in protein synthesis.In this study,we revealed that overexpression of SerRS promoted cellular senescence and inhibited the growth of cervical tumor xenografts in mice by triggering the senescence of tumor cells.In the nucleus,SerRS directly bound to telomeric DNA repeats and tethered more POT1 proteins to telomeres through a direct interaction between the UNE-S domain of SerRS and the OB1 domain of POT1.We further demonstrated that SerRS-induced enrichment of POT1 prevented the recruitment of telomerase to telomeres,resulting in progressive telomere shortening.Our data suggested a possible molecular link between protein synthesis and telomere length control,the deregulation of which may be associated with aging and cancer. | Yingxi Li Xiyang Li Mei Cao Yuke Jiang Jie Yan Ze Liu Rongcun Yang Xu Chen Peiqing Sun Rong Xiang Longlong Wang Yi Shi | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 1 |
| 15 | Effects of parecoxib on morphine analgesia after gynecology tumor operation: a randomized trial of parecoxib used in postsurgical pain management显示文摘 | Lidan Nong Yi Sun Yuke Tian Hongying Li Haifeng Li | 2013 | Journal of Surgical Research2013，，2： | 1 |
| 16 | Structural and superconducting properties of LaFeAs_(1-x)Sb_xO_(1-y)F_y显示文摘We report the antimony(Sb) doping effect in a prototype system of iron-based superconductors LaFeAsO1-yFy(y=0,0.1,0.15).X-ray powder diffraction indicates that the lattice parameters increase with Sb content within the doping limit.Rietveld structural refinements show that,with the partial substitution of Sb for As,the thickness of the Fe2As2 layers increases significantly,whereas that of the La2O2 layers shrinks simultaneously.So a negative chemical pressure is indeed 'applied' to the superconducting-active Fe2As2 layers,in contrast to the effect of positive chemical pressure by the phosphorus doping.Electrical resistance and magnetic susceptibility measurements indicate that,while the Sb doping hardly influences the SDW anomaly in LaFeAsO,it recovers SDW order for the optimally-doped sample of y=0.1.In the meantime,the superconducting transition temperature can be raised up to 30 K in LaFeAs1-xSbxO1-yFy with x=0.1 and y=0.15.The Sb doping effects are discussed in term of both J1-J2 model and Fermi Surface(FS) nesting scenario. | WANG Cao,MA ZhiFeng,JIANG Shuai,LI YuKe,XU ZhuAn & CAO GuangHan* Department of Physics,Zhejiang University,Hangzhou 310027,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，7： | 1 |
| 17 | Behavior and functional modeling methods of doubly salient electromagnetic generators for aircraft electrical power system applications显示文摘The Doubly Salient Electromagnetic Generator(DSEG) is a promising candidate in aircraft generator application due to the simplicity, robustness and reliability. However, the field windings and the armature windings are strongly coupled, which makes the inductance characteristics non-linear and too complex to model. The complex model with low precision also leads to difficulties in modeling and analysis of the entire aircraft Electrical Power System(EPS). A behavior level modeling method based on modified inductance Support Vector Machine(SVM) is proposed. The Finite Element Analysis(FEA) inductance data are modified based on the experiment results to improve the precision. A functional level modeling method based on input–output characteristics SVM is also proposed. The two modeling methods are applied to a 9 kW DSEG prototype. The steady state and transient process precision of the proposed methods are proved by comparing with the experiment results. Meanwhile, the modeling time consumption, the application time consumption and the calculation resource demand are compared. The DSEG behavior and functional modeling methods provide precious results with high efficiency, which accelerates theoretical analysis and expands the application foreground of the DSEG in the aircraft EPS. | Yanwu XU Zhuoran ZHANG Li YU Yuke SHI | 2019 | Chinese Journal of Aeronautics2019，32，2： | 1 |
| 18 | A novel method for solving shortest tool length based on compressing 3D check surfaces relative to tool postures显示文摘Solving the shortest tool length quickly under a known tool trajectory in multi-axis machining of complex channel parts is an urgent problem in industrial production. To solve this problem, a novel and efficient method is proposed which is featured by extracting only a few necessary curves from the check surface instead of sampling the entire surface. By rotating and compressing the 3 D check surface relative to all tool postures, the boundaries of the area occupied by the 2 D compressed surfaces are the essential elements for determining the shortest tool length. A tracking-based numerical algorithm is introduced to efficiently solve the silhouette curves which are formed in compressing. To define the multi-taper shaped tool holding system(THS) which is commonly used in production, a characterization model for THS profile is established. A model for solving the shortest tool length is finally constructed based on the critical interference relationship between the THS profile and all compressed boundary curves. For acceleration, the boundary splines are segmented according to their knot vectors. Then a new concept called the axis-aligned tool length box(AATB) is introduced,which can provide a conservative range of tool length for a spline segment. By scanning the AATBs of all spline segments, the very few effective spline segments that may ultimately determine the shortest tool length are filtered out. This acceleration method makes the solution for the shortest tool length more focused and efficient. The results of experimental examples are also reported to validate the efficiency and accuracy of the proposed algorithm. | Xiangyu LI Junxue REN Ximing LV Yuke ZHOU Congle LIU | 2021 | Chinese Journal of Aeronautics2021，34，2： | 1 |
| 19 | Palladium-Catalyzed One-Step Synthesis of Stereodefined Difunctionalized Glycals显示文摘Efficiently modifying glycals by directly introducing functional groups into their double bonds is a longstanding challenge.Here,the strategy of introducing two different functional groups into 1-iodoglycals to obtain modified glycals in one step through palladium catalysis was reported for the first time,and the modified glycals contained stereodefined tetrasubstituted olefins.Using this method,various difunctionalized glycals that were difficult to form by other routes were synthesized in moderate to good yields.Control experiments and density functional theory calculations show that the palladium catalyst played dual roles in this transformation,namely,inducing nucleophilic substitution and catalyzing Suzuki coupling.The reaction intermediate was isolated and confirmed by X-ray crystallographic analysis.Furthermore,the gram-scale synthesis and facile deprotection of the target compound enhances the practicality of this strategy. | Xiao-Ping Gong Yuke Li Hong-Chao Liu Zhe Zhang Zhi-Jie Niu Ya-Nan Ding Yang An Xi Chen Yan-Chong Huang Rui-Qiang Jiao Xue-Yuan Liu Yong-Min Liang | 2023 | CCS Chemistry2023，5，3： | 0 |
| 20 | TaTIP41 and TaTAP46 positively regulate drought tolerance in wheat by inhibiting PP2A activity显示文摘Drought is a major environmental stress limiting global wheat(Triticum aestivum)production.Exploring drought tolerance genes is important for improving drought adaptation in this crop.Here,we cloned and characterized TaTIP41,a novel drought tolerance gene in wheat.TaTIP41 is a putative conserved component of target of rapamycin(TOR)signaling,and the Ta TIP41 homoeologs were expressed in response to drought stress and abscisic acid(ABA).The overexpression of Ta TIP41 enhanced drought tolerance and the ABA response,including ABA-induced stomatal closure,while its downregulation using RNA interference(RNAi)had the opposite effect.Furthermore,Ta TIP41 physically interacted with TaTAP46,another conserved component of TOR signaling.Like TaTIP41,TaTAP46 positively regulated drought tolerance.Furthermore,TaTIP41 and TaTAP46 interacted with type-2A protein phosphatase(PP2A)catalytic subunits,such as TaPP2A-2,and inhibited their enzymatic activities.Silencing TaPP2A-2 improved drought tolerance in wheat.Together,our findings provide new insights into the roles of TaTIP41 and TaTAP46 in the drought tolerance and ABA response in wheat,and their potential application in improving wheat environmental adaptability. | Jianhui Ma Yuke Geng Hong Liu Mengqi Zhang Shujuan Liu Chenyang Hao Jian Hou Youfu Zhang Daijing Zhang Weijun Zhang Xueyong Zhang Tian Li | 2023 | Journal of Integrative Plant Biology2023，65，9： | 0 |
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