|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Risk factors and natural history of breast cancer in younger Chinese women显示文摘AIM: To investigate the age differences in the risk factors, clinicopathological characteristics and patterns of treatment of female breast cancer patients. METHODS: Seven thousand one hundred and fiftytwo women with primary breast cancer from the Hong Kong Breast Cancer Registry were recruited after receiving patients' consent, they were asked to complete standardized questionnaires which captured their sociodemographic characteristics and risk factors associated with breast cancer development. Among them, clinicopathological data and patterns of treatment were further collected from medical records of 5523 patients with invasive breast cancers. Patients were divided into two groups according to the age at diagnosis: younger(< 40 years old) vs older patients(≥ 40 years old) for subsequent analyses.RESULTS: Analysis on the sociodemographic characteristics and exposure to risk factors were performed on 7152 women with primary breast cancer and the results revealed that younger patients were more likely to have unhealthy lifestyles; these include a lack of exercise(85.4% vs 73.2%, P < 0.001), having high stress in life(46.1% vs 35.5%, P < 0.001), having dairy/meat-rich diets(20.2% vs 12.9%, P < 0.001),having alcohol drinking habit(7.7% vs 5.2%, P = 0.002). Younger patients were also more likely to have hormone-related risk factors including nulliparity(43.3% vs 17.8%, P < 0.001) and an early age at menarche(20.7% vs 13.2%, P < 0.001). Analyses on clinicopathological characteristics and patterns of treatment were performed on 5523 women diagnosed with invasive breast cancer. The invasive tumours in younger patients showed more aggressive pathological features such as having a higher percentage of grade 3 histology(45.7% vs 36.5%, P < 0.001), having a higher proportion of tumours with lymphovascular invasion(39.6% vs 33.2%, P = 0.003), and having multifocal disease(15.7% vs 10.3%, P < 0.001); they received different patterns of treatment than their older counterparts.CONCLUSION: Younger patients in Hong Kong are more likely to encounter risk factors associated with breast cancer development and have more aggressive tumours than their older counterparts. | Winnie Yeo Hang-Mei Lee Amy Chan Emily YY Chan Miranda CM Chan Keeng-Wai Chan Sharon WW Chan Foon-Yiu Cheung Polly SY Cheung Peter HK Choi Josette SY Chor William WL Foo Wing-Hong Kwan Stephen CK Law Lawrence PK Li Janice WH Tsang Yuk Tung Lorna LS Wong Ting-Ting Wong Chun-Chung Yau Tsz-Kok Yau Benny CY Zee | 2014 | World Journal of Clinical Oncology2014，5，5： | 4 |
| 2 | Endovascular repair of giant traumatic pseudoaneurysm of the common carotid artery显示文摘BACKGROUND: Delayed presentation of carotid artery pseudoaneurysm following many years after self-inflicted penetrating injury of the neck is extremely rare. Open surgical carotid repair may involve sternotomy for proximal vascular control. Endovascular treatment is evolving as a lessinvasive treatment option.METHODS: We report a 55-year-old man with a history of paranoid schizophrenia who presented with a progressively enlarging left sided neck mass many years after attempted suicide. CT scan confirmed a 6 cm pseudoaneurysm arising from the common carotid artery.RESULTS: Through an open retrograde puncture of the distal common carotid artery, the common carotid pseudoaneurysm was successfully repaired with a BARD fluency carotid stentgraft of 8 mm×80 mm(BARD, Tempe, AZ). The patient recovered well with no neurological deficits and was discharged on postoperative day 4. Dual antiplatelet agents of aspirin and clopidogrel were given for six months and then clopidogrel was administered lifelong. The neck mass decreased in size gradually and became non pulsatile upon follow-up.CONCLUSION: Endovascular stenting of giant carotid pseudoaneurysm is an acceptable less invasive treatment option for giant carotid pseudoaneurysm. Long-term follow-up and a greater number of cases are mandatory to establish the safety of this strategy. | Yuk Law Yiu Che Chan Stephen W.Cheng | 2015 | World Journal of Emergency Medicine2015，6，3： | 2 |
| 3 | EUS-guided injection of cyanoacrylate for bleeding gastric varices显示文摘 | Yuk Tong Lee Francis K.L. Chan Enders K.W. Ng Vincent K.S. Leung Kai Bo Law Man Yee Yung S.C.Sydney Chung Joseph J.Y. Sung | 2000 | Gastrointestinal Endoscopy2000，，2： | 1 |
| 4 | Laparoscopic Repair for Perforated Peptic Ulcer: A Randomized Controlled Trial显示文摘 | Wing T. Siu Heng T. Leong Bonita K. B. Law Chun H. Chau Anthony C. N. Li Kai H. Fung Yuk P. Tai Michael K. W. Li | 2002 | Annals of Surgery2002，，3： | 1 |
| 5 | Usefulness of plasma B-type natriuretic peptide to identify ventricular dysfunction in pediatric and adult patients with congenital heart disease显示文摘 | Yuk M. Law Bradley B. Keller Brian M. Feingold Gerard J. Boyle | 2005 | The American Journal of Cardiology2005，，4： | 1 |
| 6 | Impacts of Information and Communication Technologies (ICT) on Time Use and Trav- el Behavior: a Structural Equations Analysis 显示文摘 | Donggen Wang Fion Yuk Ting Law | 2007 | Transportation2007，34，4： | 1 |
| 7 | Impacts of Information and Communication Technologies (ICT) on time use and travel behavior: a structural equations analysis显示文摘 | Donggen Wang Fion Yuk Ting Law | 2007 | Transportation2007，，4： | 1 |
| 8 | Accuracy of plasma B-type natriuretic peplide to diagnose significant cardiovascular disease in children显示文摘 | Yuk M Law MD Andrew W | 2009 | J Am Coll Cardiol2009，54，15： | 1 |
| 9 | Impacts of wetting-drying cycles on short-term carbon and nitrogen dynamics in Amynthas earthworm casts显示文摘Effects of earthworm casts on soil nutrient dynamics and their responses to changing moisture availability in subtropical ecosystems remain poorly understood.This study aimed to examine short-term carbon(C)and nitrogen(N)dynamics and their interactions with wetting-drying cycles in three different structural forms(i.e.,granular,globular,and heap-like)of Amynthas earthworm casts.The rates of C and N mineralization in the earthworm casts were examined under two different wetting-drying cycles(i.e.,2-d and 4-d wetting intervals)using a rainfall simulation experiment.After three simulated rainfall events,subsamples of the earthworm casts were further incubated for 4 d for the determination of CO2 and N2O fluxes.The results of this study indicated that the impacts of wetting-drying cycles on the short-term C and N dynamics were highly variable among the three cast forms,but wetting-drying cycles significantly reduced the cumulative CO2 and N2O fluxes by 62%-83%and 57%-85%,respectively,when compared to the control without being subjected to any rainfall events.The C mineralization rates in different cast forms were affected by the amount of organic substrates and N content in casts,which were associated with the food preference and selection of earthworms.Meanwhile,the cumulative N2O fluxes did not differ among the three cast forms.Repeated wetting and drying of casts not only enhanced aggregate stability by promoting bonds between the cast particles,but also inhibited microbial survival and growth during the prolonged drying period,which together hindered decomposition and denitrification.Our findings demonstrated that the interactions between the structural forms,aggregate dynamics,and C and N cycling in the earthworm casts were highly complex. | Michelle Man Suet LAW Derrick Yuk Fo LAI | 2021 | Pedosphere2021，31，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员