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| 1 | The design of HEPS global timing system显示文摘Purpose The high energy photon source(HEPS)is a 4th generation synchrotron light source under construction by the institute of high energy physics.The accelerator complex consists of a 500-MeV Linac,a full-energy synchrotron booster,a 6-GeV synchrotron storage ring(SR),and three e-beam transport lines for injection and extraction among accelerators.A global timing system(GTS)covers the timing needs for all accelerator,beamline,and experiment systems.The GTS is designed to coordinate the injection processes and various measurements and protections.Most systems require that the RMS jitter of the GTS signal is less than 30 ps,while the trigger jitters for the electron gun and SR injection and extraction kickers are less than 10 ps.Method The HEPS GTS is an event-based timing system based on MicroTCA.4 hardware architecture.The MicroTCA.4300 series products from the micro-research Finland Oy are implemented in the HEPS GTS system.Results and conclusions The RMS jitter,integrated from 1 Hz to 10 MHz,of the 166.6 MHz event clock is 5.489 ps.The RMS jitter of TTL outputs is less than 30 ps.This paper reports the design of the HEPS GTS,which satisfies all of the HEPS physics requirements for timing with preliminary test results shown. | Fang Liu Ge Lei Zhe Duan Cai Meng Chenyan Lu Yanhua Shao Xinpeng Ma Nan Gan Yuemei Peng Jianshe Cao Chungming Chu Yanfeng Sui Jingyi Li IHEP | 2021 | Radiation Detection Technology and Methods2021，5，3： | 1 |
| 2 | Development of the pulse bump magnet in HEPS显示文摘Purpose In the extraction process from booster to storage ring(BTS)for high energy photon source(HEPS),the implementation of four pulse bump magnets plays a crucial role in creating a localized bump.This serves to effectively reduce the upstream kicker strength and facilitate the extraction procedure.In this paper,the development of four pulse bump magnets is presented,which were meticulously designed and thoroughly discussed,taking into consideration dynamic characteristics of the pulse magnet such as magnetic field,eddy current,induced voltage,and vibration.Methods The magnetic field and eddy currents of the pulse bump magnet were calculated through simulation using OPERA/ELLEKTRA,based on the 3D model.The design of the magnet incorporated the utilization of eddy currents within the vacuum chamber to achieve improved field uniformity.Furthermore,the measurements were performed to validate the magnet's design.Results The central magnetic field,integral magnetic field,effective length,and field uniformity measured for the first magnet meet the design specifications.The temperature measurement of the first magnet indicates that the temperature in the magnet was within acceptable limits.The measurement results for the other three magnets are consistent with those of the first one.Conclusions The magnetic field performances of four pulse bump magnets meet the physical requirements for beam extraction in BTS of HEPS.Additionally,the magnets have demonstrated reliable operation during extended testing periods. | Lihua Huo Jinhui Chen Guanwen Wang Lei Wang Yuemei Peng Zhe Duan Yuanyuan Guo Guanjian Wu Xinzhe Zhai | 2023 | Radiation Detection Technology and Methods2023，7，4： | 1 |
| 3 | Optimal dipole-field profiles for emittance reduction in storage rings显示文摘 | Wang Chunxi Wang Yusong Peng Yuemei | 2011 | PhysicalReview Spe- cial Topic-Accelerators and Beams2011，14，3： | 1 |
| 4 | Study on the fringe field effects in HEPS booster显示文摘Purpose The High Energy Photon Source(HEPS)is a 6 GeV diffraction-limited storage ring light source being built in China.HEPS booster ramps the beam energy from 500 MeV to 6 GeV with a repetition rate of 1 Hz.For the beam dynamics simulations,the consideration of the fringe field effects is not ignorable.Method To this end,several methods based on one-dimensional and three-dimensional magnetic fields are used to model the dipoles and quadrupoles of booster.Results and conclusion In this paper,we evaluate the impacts of magnetic fringe field effects of dipoles and quadrupoles on the optics of the HEPS booster. | Yuanyuan Guo Nan Li Yuemei Peng Daheng Ji Hongfei Ji Yi Jiao | 2023 | Radiation Detection Technology and Methods2023，7，3： | 1 |
| 5 | Equilibrium electron beam parameters of the High Energy Photon Source显示文摘Purpose The physics design of the High Energy Photon Source(HEPS)was finished after many times of iteration.Hereby,the typical equilibrium electron beam parameters corresponding to the proposed two baseline operation modes in the baseline design of HEPS are presented.Methods To compute the equilibrium parameters of the electron beam,the lattice parameters,RF parameters,and the parameters of the insertion devices(IDs)were determined first.Furthermore,it is more precise to use the full-current electron beam parameters in the estimations of the performance of the synchrotron light.Therefore,not only the single-particle dynamics but also the current-dependent collective effects need to be considered in the computations of the full-current,equilibrium parameters of the electron beam.Both analytic computations and multi-particle tracking simulations were carried out.Results The full-current,equilibrium parameters of the electron beams in the HEPS storage ring are presented in this paper.Moreover,the main beam parameters in the injector(the booster and the LINAC),corresponding to the two baseline operation modes of the storage ring,are also presented.Conclusion The typical electron beam parameters corresponding to the two baseline operation modes are given in detail in this paper. | Haisheng Xu Cai Meng Yuemei Peng Saike Tian Na Wang Xiaohao Cui Chongchong Du Zhe Duan Yuanyuan Guo Ping He Xiyang Huang Daheng Ji Hongfei Ji Yi Jiao Jingyi Li Nan Li Xiaoyu Li Xiaohan Lu Pengfei Liang Weimin Pan Huamin Qu Bin Wang Jiuqing Wang Yuanyuan Wei Jinyu Wan Gang Xu Fang Yan Chenghui Yu Sen Yue Xiang Zhang Yaliang Zhao | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 6 | Transfer matrices of dipoles with bending radius variation显示文摘With the increasing demand of high brightness in light source, the uniform dipole can not meet the needs of low emittance, and thus the dipole with bending radius variation is introduced in this paper. The transfer matrix of a non-uniform dipole whose bending radius is linearly changed is chosen as an example and a very simple calculation formula of non-uniform dipole transfer matrices is given. The transfer matrices of some common profile non-uniform dipoles are also listed. The comparison of these transfer matrices and the matrices calculated with slices method verifies the numerical accuracy of this formula. This method can make the non-uniform beam dynamic problem simpler, very helpful for emittance research and lattice design with non-uniform dipoles. | PENG YueMei XU Gang | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 0 |
| 7 | Sorting nexin 3 exacerbates doxorubicin-induced cardiomyopathy via regulation of TFRC-dependent ferroptosis显示文摘The clinical utilization of doxorubicin(Dox)in various malignancies is restrained by its major adverse effect:irreversible cardiomyopathy.Extensive studies have been done to explore the prevention of Dox cardiomyopathy.Currently,ferroptosis has been shown to participate in the incidence and development of Dox cardiomyopathy.Sorting Nexin 3(SNX3),the retromer-associated cargo binding protein with important physiological functions,was identified as a potent therapeutic target for cardiac hypertrophy in our previous study.However,few study has shown whether SNX3 plays a critical role in Dox-induced cardiomyopathy.In this study,a decreased level of SNX3 in Dox-induced cardiomyopathy was observed.Cardiac-specific Snx3 knockout(Snx3-cKO)significantly alleviated cardiomyopathy by downregulating Dox-induced ferroptosis significantly.SNX3 was further demonstrated to exacerbate Dox-induced cardiomyopathy via induction of ferroptosis in vivo and in vitro,and cardiac-specific Snx3 transgenic(Snx3-cTg)mice were more susceptible to Dox-induced feroptosis and cardiomyopathy.Mechanistically,SNX3 facilitated the recycling of transferrin 1 receptor(TFRC)via direct interaction,disrupting iron homeostasis,increasing the accumulation of iron,triggering ferroptosis,and eventually exacerbating Dox-induced cardiomyopathy.Overall,these findings established a direct SNX3-TFRC-ferroptosis positive regulatory axis in Dox-induced cardiomyopathy and suggested that targeting SNX3 provided a new effective therapeutic strategy for Dox-induced cardiomyopathy through TFRCdependentferroptosis. | Wenjing Yu Yuehuai Hu Zhiping Liu Kaiteng Guo Dinghu Ma Mingxia Peng Yuemei Wang Jing Zhang Xiaolei Zhang Panxia Wang Jiguo Zhang Peiqing Liu Jing Lu | 2023 | Acta Pharmaceutica Sinica B2023，13，12： | 0 |
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