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| 1 | Variations between rice cultivars in iron and manganese plaque on roots and the relation with plant cadmium uptake显示文摘To understand certain mechanisms causing variations between rice cultivars with regard to cadmium uptake and tolerance,pot soil experiments were conducted with two rice cultivars of different genotypes under different soil Cd levels.The relationships between plant Cd uptake and iron/manganese(Fe/Mn) plaque formation on roots were investigated.The results showed that rice cultivars di?ered markedly in Cd uptake and tolerance.Under soil Cd treatments,Cd concentrations and accumulations in the cultivar Shanyou 63(the genotype indica) were significantly higher than those in the cultivar Wuyunjing 7(the genotype japonica)(P < 0.01,or P < 0.05),and Shanyou 63 was more sensitive to Cd toxicity than Wuyunjing 7.The differences between the rice cultivars were the largest at relatively low soil Cd level(i.e.,10 mg/kg).Fe concentrations in dithionite-citrate-bicarbonate root extracts of Shanyou 63 were generally lower than that of Wuyunjing 7,and the difference was the most significant under the treatment of 10 mg Cd/kg soil.The results indicated that the formation of iron plaque on rice roots could act as a barrier to soil Cd toxicity,and may be a 'buffer' or a 'reservoir' which could reduce Cd uptake into rice roots.And the plaque may contribute,to some extent,to the genotypic differences of rice cultivars in Cd uptake and tolerance. | Jianguo Liu Changxun Cao Minghung Wong Zhijun Zhang Yuhong Chai | 2010 | Journal of Environmental Sciences2010，22，7： | 43 |
| 2 | Vision,Requirements and Network Architecture of 6G Mobile Network beyond 2030显示文摘With the 5th Generation(5G)Mobile network being rolled out gradually in 2019,the research for the next generation mobile network has been started and targeted for 2030.To pave the way for the development of the 6th Generation(6G)mobile network,the vision and requirements should be identified first for the potential key technology identification and comprehensive system design.This article first identifies the vision of the society development towards 2030 and the new application scenarios for mobile communication,and then the key performance requirements are derived from the service and application perspective.Taken into account the convergence of information technology,communication technology and big data technology,a logical mobile network architecture is proposed to resolve the lessons from 5G network design.To compromise among the cost,capability and flexibility of the network,the features of the 6G mobile network are proposed based on the latest progress and applications of the relevant fields,namely,on-demand fulfillment,lite network,soft network,native AI and native security.Ultimately,the intent of this article is to serve as a basis for stimulating more promising research on 6G. | Guangyi Liu Yuhong Huang Na Li Jing Dong Jing Jin Qixing Wang Nan Li | 2020 | China Communications2020，17，9： | 37 |
| 3 | Optimization approach of background value and initial item for improving prediction precision of GM(1,1) model显示文摘A combination method of optimization of the background value and optimization of the initial item is proposed. The sequences of the unbiased exponential distribution are simulated and predicted through the optimization of the background value in grey differential equations. The principle of the new information priority in the grey system theory and the rationality of the initial item in the original GM(1,1) model are fully expressed through the improvement of the initial item in the proposed time response function. A numerical example is employed to illustrate that the proposed method is able to simulate and predict sequences of raw data with the unbiased exponential distribution and has better simulation performance and prediction precision than the original GM(1,1) model relatively. | Yuhong Wang Qin Liu Jianrong Tang Wenbin Cao Xiaozhong Li | 2014 | Journal of Systems Engineering and Electronics2014，25，1： | 32 |
| 4 | Proteomics Associated with Virulence Differentiation of Curvularia lunata in Maize in China显示文摘蛋白质的一个维的电气泳动(1-DE ) ,蛋白质的 two-dimensionalelectrophoresis (2-DE ) 并且 cDNA 顺序克隆被用来学习 Curvularia lunata 的毒力区别[Cochliobolus lunatus ] 在中国从玉米(Zea maydis ) 孤立。从蛋白质的 1-DE 胶化侧面, 110 个可再现的乐队与六被分开 C 孤立。lunata CX-3, SD-6, C-152, C107-1, DD-60 和 W-18。68 个乐队(61.82%) 是多态的,建议在 isolates 之中的巨大的生物多样性。所有孤立组由 0.605 的系数价值由不同剧毒的类型组成因为实验被聚类进三。组织 1,由有高毒力的 CX-3, SD-6 和 C-152 组成比组显示了更多的蛋白质乐队第 2a 3,与低毒力由 C107-1 和 DD-60 组成。Proteomics 途径基于 2-DEtechniques 被使用识别在 CX-3 和 DD-60 与毒力区别联系的特定的蛋白质。423 个蛋白质点的一个总数被分开。从他们, 75 个特定的蛋白质点在 2-DE 胶化被显示。在他们之中, 28 个蛋白质点在 CX-3 是唯一的, 8 在两 2-DE 胶化上在 DD-60,和 39 个蛋白质点被显示出,但是在紧张不同地表示。包括三个唯一的蛋白质点和 17 差别的 Twentyprotein 点在 CX-3 表示了蛋白质点(超过 2 褶层 DD-60 ) 进一步与 MALDI-TOF MS/MS 被识别。结果显示大多数识别蛋白质被发现与毒力区别,新陈代谢,压力反应和信号转导被联系。他们之一作为 Brn1 蛋白质被识别,它被报导了在真菌与黑素生合成和毒力区别有关。与我们的以前的调查结果结合了,我们假设那 Brn1 蛋白质和它的调整产品可能涉及 C 的毒力区别。lunata。因而,我们克隆 Brn1cDNA 碎片并且在另外的真菌与碎片联盟。结果显示 Brn1 的 633-bpsequence 在 C 克隆。lunata 是高度与比较真菌逻辑的人。为在我们的情况中的 Brn1 的准确基因角色的进一步的工作是在进行之中的…… | Shufa Xu Jie Chen Lixing Liu Xiaofei Wang Xiuli Huang Yuhong Zhai | 2007 | Journal of Integrative Plant Biology2007，49，4： | 25 |
| 5 | A comparative study between graphene oxide and diamond nanoparticles as water-based lubricating additives显示文摘The tribological properties of graphene oxide(GO) nanosheets and modified diamond(MD) nanoparticles with excellent water-solubility were investigated.GO nanosheets were synthesized using carbon fibers with a regular and uniform size,the lateral size being around 30 nm and the thickness being 2 or 3 nm,while MD nanoparticles were about 30 nm in the three dimensions.The friction properties of ceramics were improved by GO nanosheets or MD nanoparticles used as additives in water-based lubrication,though the effects of two nanoparticles were quite different.For GO nanosheets,the friction coefficient at the beginning decreased sharply from 0.6 to 0.1,as compared with the dionized water lubrication.At the same time,the running-in period was shortened from 2000 s to 250 s.A steady state characterized by ultralow friction(friction coefficient=0.01) was obtained after the running-in period.In the case of MD nanoparticles,the friction coefficient stayed at 0.1 without further decrease during the whole experiment.Based on the observation of wear scar and characterization of remains on the wear track,the positive effect of GO nanosheets was attributed to their lamellar structure and geometric size.MD nanoparticles reduced friction by forming the regularly grained surface on the mating surfaces,and prevented further reduction in steady-state friction coefficient owing to their larger size and hardness.In conclusion,GO nanosheets exhibited favorable potential as an effective additive for water-based lubrication. | LIU YuHong WANG XiaoKang PAN GuoShun LUO JianBin | 2013 | Science China(Technological Sciences)2013，56，1： | 21 |
| 6 | Effect of ultrasound-guided acupotomy vs electro-acupuncture on knee osteoarthritis:a randomized controlled study显示文摘OBJECTIVE:To investigate the effect of acupotomy on knee osteoarthritis(KOA),compared to electro-acupuncture(EA).METHODS:Sixty KOA patients were randomly divided into 2 groups:ultrasound-guided acupotomy group and EA group;each had 3 weeks' therapy.After the treatment,by contrast before and after therapy,by comparing curative effects among groups,we looked into disease improvement degree through activities of daily living score(ADL),hospital for special surgery index(HSS),visual analogue scales score(VAS) and knee joint's infrared thermal imaging detection.RESULTS:Graded by ADL,the excellent rate in acupotomy group was much higher than EA group;both acupotomy group and EA group had obviouschanges in HSS index before and after the therapy(P < 0.01).And there was remarkable difference in HSS index variation between the groups(P < 0.01).Acupotomy group and EA group showed big difference in pain index before and after treatment(P <0.01).Apparent difference also existed in the comparison among groups(P < 0.01).Both acupotomy group and EA group had apparent changes in infrared thermal imaging detection before and after the treatment(P < 0.01).CONCLUSION:Acupotomy and EA both have significant effects in KOA treatment;the former is better than the latter in relieving pain and improving knee functions. | Ding Yu Wang Yuexiang Shi Xian Luo Yun Gao Yuhong Pan Jingkun | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 21 |
| 7 | Dusty cloud radiative forcing derived from satellite data for middle latitude regions of East Asia显示文摘尘封的云在东亚的中间的纬度区域上的放射的强迫被使用估计 2 年(7 月 2002-June 日 2004 ) 并置的云和地球的绚烂的精力系统(谷神星) 的数据从水编辑 1B SSF (单个扫描仪脚印) 的扫描仪和中等分辨率成像分光辐射函数(MODIS ) 。尘封的云在灰尘暴风雨环境被定义为云或灰尘污染了云。为面对灰尘成长的云,在空气(TOA ) 的顶强迫的即时短波(SW ) 关于 -275.7 W/m 2 为阴郁灰尘(货到付款) 区域。在没有灰尘开发云(CLD ) 区域的云产出最否定的短波(SW ) forcint (是大约 12.8% 的 -311.0 W/m 2), 比那些强壮在货到付款区域。为长波浪(LW ) 放射的强迫,没有灰尘云(CLD ) 在是 20% 的 102.8 W/m 2, 附近不到从货到付款区域强迫的 LW。为 CLD 区域的放射的强迫关于是 42.1% 的 -208.2W/m2, 的即时 TOA 网比货到付款区域的价值大。在云下面的灰尘喷雾器的存在显著地减少云的冷却效果。 | HUANG Jianping WANG Yujie WANG Tianhe YI Yuhong | 2006 | Progress in Natural Science:Materials International2006，16，10： | 20 |
| 8 | Assessment of Point and Nonpoint Sources Pollution in Songhua River Basin,Northeast China by Using Revised Water Quality Model显示文摘Individual participation of pollutants in the pollution load should be estimated even if roughly for the appropriate environmental management of a river basin.It is difficult to identify the sources and to quantify the load, especially in modeling nonpoint source.In this study a revised model was established by integrating point and nonpoint sources into one-dimensional Streeter-Phelps(S-P) model on the basis of real-time hydrologic data and surface water quality monitoring data in the Jilin Reach of the Songhua River Basin.Chemical oxygen demand(COD) and ammonia nitrogen(NH 3-N) loads were estimated.Results showed that COD loads of point source and nonpoint source were 134 958 t/yr and 86 209 t/yr, accounting for 61.02% and 38.98% of total loads, respectively.NH 3-N loads of point source and nonpoint source were 16 739 t/yr and 14 272 t/yr, accounting for 53.98% and 46.02%, respectively.Point source pollution was stronger than nonpoint source pollution in the study area at present.The water quality of upstream was better than that of downstream of the rivers and cities.It is indispensable to treat industrial wastewater and municipal sewage out of point sources, to adopt the best management practices to control diffuse pollutants from agricultural land and urban surface runoff in improving water quality of the Songhua River Basin.The revised S-P model can be successfully used to identify pollution source and quantify point source and nonpoint source loads by calibrating and validating. | YANG Yuhong YAN Baixing SHEN Wanbin | 2010 | Chinese Geographical Science2010，20，1： | 13 |
| 9 | Comprehensive review of telbivudine in pregnant women with chronic hepatitis B显示文摘AIM:To achieve an evidence-based conclusion regarding the safety and efficacy of telbivudine during pregnancy.METHODS:A pooled analysis of data from a literature search reported 1739 pregnancy outcomes(1673 live births)from 1725 non-overlapping pregnant women treated with telbivudine.The prevalence of live birth defects(3.6/1000)was similar to that of the nonantiviral controls(3.0/1000)and not increased as compared with overall prevalence(14.5 to 60/1000).No target organ toxicity was identified.The prevalence of spontaneous abortion in pregnant women treated with telbivudine(4.2/1000)was not increased compared with the overall prevalence(16/1000).The mother-to-child transmission rate was significantly reduced in pregnant women treated with telbivudine(0.70%)compared to those treated with the non-antiviral controls(11.9%;P<0.0001)or compared to the historical rates of hepatitis B virus(HBV)-infected population without antiviral treatment(10%-15%).RESULTS:Cumulatively 489 pregnancy cases have been reported in the telbivudine pharmacovigilance database(with a cut-off date 31 August 2014),of those,308 had known pregnancy outcomes with 249 cases of live births(239 cases of live birth without congenital anomaly and 10 cases of live birth with congenital anomaly).In the latest antiretroviral pregnancy registry report(1 January 1989 through 31 January 2015)of27 patients exposed to telbivudine during pregnancy(18,6 and 3 during first,second and third trimester,respectively)19 live births were reported and there were no cases of birth defects reported.CONCLUSION:Telbivudine treatment during pregnancy presents a favorable safety profile without increased rates of live birth defects,spontaneous abortion or elective termination,or fetal/neonatal toxicity.Exposure to telbivudine in the first,second and third trimester of pregnancy has been shown to significantly reduce the risk of HBV transmission from mother to child on the basis of standard immune prophylaxis procedure. | Teerha Piratvisuth Guo Rong Han Stanislas Pol Yuhong Dong Aldo Trylesinski | 2016 | World Journal of Hepatology2016，8，9： | 13 |
| 10 | Compound Zhebei granules combined with chemotherapy for the treatment of refractory acute leukemia: a randomized clinical trial显示文摘OBJECTIVE: To observe the effect of compound Zhebei granules(CZBG) with chemotherapy in the treatment of refractory acute leukemia.METHODS: In this multicenter, double-blind, placebo-controlled clinical trial, we used a central(online) randomization system to assign 235 patients to two treatment groups. A total of 118 patients received chemotherapy combined with CZBG(4 g,twice daily) and 117 patients received chemotherapy plus placebo. The clinical efficacy was evaluated at the end of one chemotherapeutic cycle.RESULTS: In the full analysis set, in which deaths due to disease progression were regarded as inefficacy, the rates of complete remission(CR) and partial remission(CR + PR) were 32.35% and 50.00%,respectively, for the chemotherapy combined with CZBG group, and 23.08% and 35.58%, respectively,for the chemotherapy plus placebo group. There was a statistically significant difference between the two groups according to a ysis set(PPχ2test(P < 0.05). In the per protocol analS), the CR(33.67%),CR+PR(52.04%) response rates for the chemotherapy plus CZBG group were significantly different from the response rates of the control group(CR:24.24% and CR+PR: 37.37%), respectively(P < 0.05).CONCLUSION: CZBG plus chemotherapy can improve the clinical remission rate of refractory acute leukemia after one just one therapeutic cycle. | Hou Li Yang Shulian Yang Wenhua Zhou Yuhong Liu Feng Yang Hongyong Sun Weizheng Li Dongyun Xu Yamei Chen Xinyi | 2016 | Journal of Traditional Chinese Medicine2016，36，5： | 13 |
| 11 | Pyrolysis of oil at high temperatures:Gas potentials,chemical and carbon isotopic signatures显示文摘Although the gas cracked from oil has been believed to be one of the important sources in highly matured marine basins, there are still some debates on its resource potentials and chemical and isotopic compositions. In this study a Cambrian-sourced marine oil sample from the Silurian reservoir of well TZ62 in the central Tarim basin was pyrolyzed using sealed gold tubes with two different pyrolysis schemes: continuous pyrolysis in a closed system and stepwise semi-open pyrolysis. The results show that the maximum weight yield of C1-5 gases occurs at EasyRo=2.3% and the residual gas poten-tial after this maturity is only 43.4 mL/g, about 12% of the yield of 361 mL/g at EasyRo=2.3%. Combined with the results of kinetic modeling, the main stage of gas generation from oil cracking is believed within the EasyRo=1.6%―2.3%. The increase in the volume yield of C1-5 gases at EasyRo>2.3% in a closed system is mainly related to the re-cracking of previously formed C2-5 wet gases, not the direct cracking of oil. The stepwise pyrolysis experiments show that the gas from the cracking of residual oil at EasyRo>2.3% is characterized by very high dryness index (higher than 92%) and heavy methane carbon isotopes ranging from ?28.7‰ to ?26.7‰, which is quite different from the gases from the con-tinuous pyrolysis in a closed system. The kinetic modeling of methane carbon isotope fractionation shows that the carbon isotopes of methane within the main stage of gas generation (EasyRo<2.3%) are far lighter than the carbon isotopes of the precursor oils under a geological heating rate of 2 ℃ /Ma. The above observations and results provide some new clues to the accurate recognition and objective resource evaluation of oil cracking gas in highly mature marine basins. | TIAN Hui XIAO XianMing YANG LiGuo XIAO ZhongYao GUO LiGuo SHEN JiaGui LU YuHong | 2009 | Chinese Science Bulletin2009，54，7： | 12 |
| 12 | Characteristics and accumulation mechanisms of the Dongfang 13-1 high temperature and overpressured gas field in the Yinggehai Basin, the South China Sea显示文摘The Dongfang 13-1 is located in the diapiric structure belt of the Yinggehai Basin. The formation pressure of its main gas reservoir in the Miocene Huangliu Formation is up to 54.6 MPa(pressure coefficient=1.91) and the temperature is as high as 143°C(geothermal gradient 4.36°C/100 m), indicating that it is a typical high-temperature and overpressured gas reservoir. The natural gas is interpreted to be coal-type gas derived from the Miocene mature source rocks containing type II2-III kerogens as evidenced by high dryness index of up to 0.98 and heavy carbon isotopes, i.e., the δ13C1 ranging from -30.76‰ to -37.52‰ and δ13C2 ranging from -25.02‰ to -25.62‰. The high temperature and overpressured Miocene petroleum system is related mainly to diapir in the Yinggehai Basin and contains more pore water in the overpressured reservoirs due to undercompaction process. The experimental and calculated results show that the solubility of natural gas in formation water is as high as 10.5 m3/m3 under the temperature and pressure conditions of the Sanya Formation, indicating that at least part of the gas may migrate in the form of water-soluble phase. Meanwhile, the abundant gas source in the Basin makes it possible for the rapid saturation of natural gas in formation water and exsolution of soluble gas. Therefore, the main elements controlling formation of the Dongfang 13-1 gas pool include that(1) the diapir activities and accompanying changes in temperature and pressure accelerate the water-soluble gas exsolution and release a lot of free gas;(2) submarine fan fine sandstone in the Huangliu Formation provides good gas-water segregation and accumulation space; and(3) the overlying overpressured mud rocks act as effective caps. The accumulation mechanism reveals that the high temperatural and high pressure structure belt near the diapir structures has a good potential for large and medium-sized gas field exploration. | XIE YuHong HUANG BaoJia | 2014 | Science China Earth Sciences2014，57，11： | 12 |
| 13 | Effect of kidney-reinforcing,blood-activating and stasis-removing recipes on adhesion molecule expression of bone marrow mesenchymal stem cells from chronic aplastic anemia patients显示文摘OBJECTIVE:To explore the effect of kidney-reinforcing,blood-activating and stasis-removing recipes on adhesion molecule expression of bone marrow mesenchymal stem cells(MSCs) from patients with chronic aplastic anemia(CAA).METHODS:We used threeTraditional Chinese Medicine recipes,namely a kidney-reinforcing recipe(KRR),blood-activating and stasis-removing recipe(BASRR),and kidney-reinforcing,blood-activating and stasis-removing recipe(KRBASRR),and a normal saline control to prepare herbal medicine serum in Sprague Dawley rats.Thirty CAA patients were enrolled in the experimental group,including 17 kidney-Yang deficient patients and 13 kidney-Yin deficient patients.Ten healthy individuals were included in the control group.MSCs were isolated from bone marrow samples,and the cell density was observed to measure their proliferation ability by microscopy on days 2,7,and 14 after isolation.In addition,the expression of adhesion molecules of bone marrow MSCs(CD106,CD49d,CD31 and CD44) were detected by flow cytometry after 48 h of treatment with the four different herbal medicine serums.RESULTS:The proliferation of MSCs from kidney-Yang deficient and kidney-Yin deficient patients was weaker than that of MSCs from the control group.The expression of all adhesion molecules of bone marrow MSCs from CAA patients was obviously lower than that in the control group(P< 0.01).The expression of CD49d and CD31 in MSCs from patients with a kidney-Yin deficiency was lower than in those with a kidney-yang deficiency(P< 0.05 and P<0.01,respectively).For kidney-Yang deficient patients,CD31 expression in the KRBASRR group was significantly higher than that in the BASRR group(P<0.01),while CD44 in the KRBASRR group was significantly higher than that in both KRR and BASRR groups(P<0.01).For kidney-Yin deficient patients,CD106 and CD49d expression in the KRBASRR group was obviously higher than that in the KRR group(P<0.05),while CD31 and CD44 expression in the KRBASRR group was significantly higher than that in both KRR and BASRR groups(P< 0.05 and P<0.01,respectively).CONCLUSION:The bone marrow microenvironment in CAA patients is abnormal.The effect of KRBASRR may be better than that of KRR and BASRR for kidney-Yang deficient and kidney-Yin deficient patients by improving the expression levels of MSC adhesion molecules. | Baodong Ye Dan Chen Dijiong Wu Xiangping Wu Xiang Zhang Yuhong Zhou Yiping Shen Keding Shao Qinhong Yu | 2012 | Journal of Traditional Chinese Medicine2012，32，4： | 12 |
| 14 | Evaluation of upper limb muscle fatigue based on surface electromyography显示文摘Fatigue is believed to be a major contributory factor to occupational injuries in machine operators.The development of accurate and usable techniques to measure operator fatigue is therefore important.In this study,we used a novel method based on surface electromyography (sEMG) of the biceps brachii and the Borg scale to evaluate local muscle fatigue in the upper limb after isometric muscle action.Thirteen young males performed isometric actions with the upper limb at different force levels.sEMG activities of the biceps brachii were recorded during the actions.Borg scales were used to evaluate the subjective sensation of local fatigue of the biceps brachii after the actions.sEMG activities were analyzed using the one-third band octave method,and an equation to determine the degree of fatigue was derived based on the relationship between the variable and the Borg scale.The results showed that the relationship could be expressed by a conic curve,and could be used to evaluate muscle fatigue during machine operation. | ZHOU QianXiang CHEN YuHong MA Chao ZHENG XiaoHui | 2011 | Science China(Life Sciences)2011，54，10： | 11 |
| 15 | Improvement and application of GM(1,1) model based on multivariable dynamic optimization显示文摘For the classical GM(1,1)model,the prediction accuracy is not high,and the optimization of the initial and background values is one-sided.In this paper,the Lagrange mean value theorem is used to construct the background value as a variable related to k.At the same time,the initial value is set as a variable,and the corresponding optimal parameter and the time response formula are determined according to the minimum value of mean relative error(MRE).Combined with the domestic natural gas annual consumption data,the classical model and the improved GM(1,1)model are applied to the calculation and error comparison respectively.It proves that the improved model is better than any other models. | WANG Yuhong LU Jie | 2020 | Journal of Systems Engineering and Electronics2020，31，3： | 11 |
| 16 | Higher PD-1 expression concurrent with exhausted CD8+ T cells in patients with de novo acute myeloid leukemia显示文摘Objective: To investigate the association between the T cell inhibitory receptor programmed death 1(PD-1)and T cell exhaustion status in T cells from patients with de novo acute myeloid leukemia(AML) and AML in complete remission(CR).Methods:Surface expression of PD-1 and the exhaustion and immunosenescence markers CD244 and CD57 on CD3+,CD4+ and CD8+ T cells from peripheral blood samples from 20 newly diagnosed,untreated AML patients and 10 cases with AML in CR was analyzed by flow cytometry.Twenty-three healthy individuals served as control.Results:A significantly higher percentage of PD-1+ cells were found for CD3+ T cells in the de novo AML group compared with healthy controls.In addition,an increased level of PD-1+ CD8+ T cells,but not PD-1+ CD4+,was found for CD3+ T cells in the de novo AML and AML-CR samples.A higher percentage of CD244+ CD4+,CD244+ CD8+,CD57+ CD4+ and CD57+ CD8+ T cells was found in CD3+ T cells in samples from those with de novo AML compared with those from healthy controls.Strong increased PD-1+ CD244+ and PD-1+ CD57+ coexpression was found for CD4+ and CD8+ T cells in the de novo AML group compared with healthy controls.Conclusions:We characterized the major T cell defects,including co-expression of PD-1 and CD244,CD57-exhausted T cells in patients with de novo AML,and found a particular influence on CD8+ T cells,suggesting a poor anti-leukemia immune response in these patients. | Jiaxiong Tan Shaohua Chen Yuhong Lu Danlin Yao Ling Xu Yikai Zhang Lijian Yang Jie Chen Jing Lai Zhi Yu Kanger Zhu Yangqiu Li | 2017 | Chinese Journal of Cancer Research2017，29，5： | 10 |
| 17 | Phase-field simulation for the evolution of solid/liquid interface front in directional solidification process显示文摘In this study, the phase field method was used to study the multi-controlling factors of dendrite growth in directional solidification. The effects of temperature gradient, propelling velocity, thermal disturbance and growth orientation angle on the growth morphology of the dendritic growth in the solid/liquid interface were discussed. It is found that the redistribution of solute leads to multilevel cavity and multilevel fusion to form multistage solute segregation, and the increase of temperature gradient and propelling velocity can accelerate the dendrite growth of directional solidification, and also make the second dendrites more developed, which reduces the primary distance and the solute segregation. When the temperature gradient is large, the solid-liquid interface will move forward in a flat interface mode,and the thermal disturbance does not affect the steady state behavior of the directionally solidified dendrite tip. It only promotes the generation and growth of the second dendrites and forms the asymmetric dendrite. Meanwhile, it is found that the inclined dendrite is at a disadvantage in the competitive growth compared to the normal dendrite, and generally it will disappear. When the inclination angle is large, the initial primary dendrite may be eliminated by its secondary or third dendrite. | Yuhong Zhao Bing Zhang Hua Hou Weipeng Chen Meng Wang | 2019 | Journal of Materials Science & Technology2019，35，6： | 10 |
| 18 | Characterization and evaluation of rice blast resistance of Chinese indica hybrid rice parental lines显示文摘The development of resistant varieties and hybrid combinations has been the most effective and economical strategy to control blast disease caused by Magnaporthe oryzae.However, the distribution of major R genes and blast resistance characterization in hybrid rice parents has not been well investigated, resulting in their limited use in hybrid rice blast-resistance breeding. In the present study, 88 elite indica hybrid rice parental lines were evaluated with 30 isolates of M. oryzae collected from the main planting area of indica hybrid rice in China and were characterized for the presence of 11 major resistance genes using molecular markers. The pathogenicity assays showed that four types of hybrid rice parent line showed some resistance to M. oryzae. However, the proportions of highly resistant lines and the mean resistance frequency(RF) varied among the four types, with resistance in decreasing order shown by three-line restorer lines, three-line maintainer lines, two-line sterile lines, and two-line restorer lines. All 88 hybrid rice parental lines carried more than one R gene, but none carried the R genes Pi1 and Pi2. Although Pid3 and Pi9 were present only in three-line restorer lines and Pigm only in three-line maintainer lines, the remaining six R genes(Pib, Pid2, Pi5, Pia, Pi54, and Pita) were present in the four types of hybrid rice parent with significantly different distribution frequencies. The correlation between R genes and resistance reactions was investigated. The results are expected to provide useful information for rational utilization of major R genes in hybrid rice breeding programs. | Yunyu Wu Ling Yu Ning Xiao Zhengyuan Dai Yuhong Li Cunhong Pan Xiaoxiang Zhang Guangqing Liu Aihong Li | 2017 | The Crop Journal2017，5，6： | 10 |
| 19 | Molecular behaviors in thin film lubrication——Part one: Film formation for different polarities of molecules显示文摘There are three unsolved problems in thin film lubrication(TFL) since it was proposed 20 years ago, i.e., the determination of the type of molecules that can enter the contact region efficiently during sliding, the orientation of molecules in the contact region, and the effect of solid surfaces on the liquid molecular orientation in TFL. In order to answer the first two questions, an in situ measurement system comprising a self-designed Raman microscopy and relative optical interference intensity(ROⅡ) system was set up to study the molecular behaviors. A variety of binary mixtures were used as lubricants in the test, and the concentration distribution profile and orientation of the additive molecules in TFL were characterized. The molecular behavior was determined via a combination of shearing, confinement, and surface adsorption. Furthermore, the difference in molecular polarity resulted in different competing effect of surface adsorption and intermolecular interaction, the influence of which on molecular behavior was discussed. Polar additive molecules interacted with the steel surface and exhibited an enrichment effect in the Hertz contact region when added into a nonpolar base oil. No enrichment effect was observed for nonpolar molecules that were added into the nonpolar base oil and polar molecules added into polar base oil. The enrichment of additive molecules enhanced the film-forming ability of the lubricant and resulted in a reduction in the friction coefficient of up to 61%. The orderly arrangement of the additive molecules was another reason for the friction-reducing. A binary multilayer model was proposed to illuminate the molecular behavior in the TFL, and the model was supported by contrary experiment results in elastohydrodynamic lubrication. This research may aid in understanding the nanoscale lubrication mechanism in TFL and the development of novel liquid lubricants. | Shaohua ZHANG Yijun QIAO Yuhong LIU Liran MA Jianbin LUO | 2019 | Friction2019，7，4： | 10 |
| 20 | The SWi2/SNF2 Chromatin-Remodeling ATPase BRAHMA Regulates Chlorophyll Biosynthesis in Arabidopsis显示文摘叶绿素生合成在植物为叶绿体开发和光合作用是批评的。尽管在叶绿素 biosynthetic 小径的反应大部分被知道了,很少对这条小径的规章的机制被知道。在这研究,我们发现象梵天(BRM ) 的 RNA 干扰转基因的幼苗一样的黑暗成年的猛烈、击倒的异种,它编码 SWI2/SNF2 改变染色质的 ATPase,有的更高的 greening 率,积累的更少 protochlorophyllide,和生产更少比 Arabidopsis,野类型的植物在轻暴露之上做了的反应的氧种类。NADPH:protochlorophyllide oxidoreductase A (PORA ) 的表示, PORB,和 PORC,在叶绿素生合成催化关键步,在 brm 异种被增加。我们发现那 BRM 身体上与 bHLH 抄写因素交往 PHYTOCHROME 因素 1 交往了(PIF1 ) 通过它的 N 终端领域。而且,我们证明 BRM 直接被招募到 PORC,然而并非 PORA 和 PORB 的 cis 规章的区域,至少,部分,以一种 PIF1 依赖的方式和 histone H3 离氨酸的水平,在 PORC loci 的 4 tri-methylation (H3K4me3 ) 在 brm 异种被增加。一起拿,我们的数据显示改变染色质的酶 BRM 通过与 PIF1 交往调制 PORC 表示,提供植物在转变期间由调整叶绿素生合成从的新奇规章的机制对自造营养物质的生长不是自养。 | Dong Zhang Yuhong Li Xinyu Zhang Ping Zha Rongcheng Lin | 2017 | Molecular Plant2017，10，1： | 10 |
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