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| 1 | Directly modulated quantum dot lasers on silicon with a milliampere threshold and high temperature stability显示文摘Microring lasers feature ultralow thresholds and inherent wavelength-division multiplexing functionalities, offering an attractive approach to miniaturizing photonics in a compact area. Here, we present static and dynamic properties of microring quantum dot lasers grown directly on exact(001) GaP/Si. Effectively, a single-mode operation was observed at 1.3 μm with modes at spectrally distant locations. High temperature stability with T_0~103 K has been achieved with a low threshold of 3 mA for microrings with an outer ring radius of 15 μm and a ring waveguide width of 4 μm. Small signal modulation responses were measured for the first time for the microrings directly grown on silicon, and a 3 dB bandwidth of 6.5 GHz was achieved for a larger ring with an outer ring radius of 50 μm and a ring waveguide width of 4 μm. The directly modulated microring laser,monolithically integrated on a silicon substrate, can incur minimal real estate cost while offering full photonic functionality. | YATING WAN DAISUKE INOUE DAEHWAN JUNG JUSTIN C.NORMAN CHEN SHANG ARTHUR C.GOSSARD JOHN E.BOWERS | 2018 | Photonics Research2018，6，8： | 4 |
| 2 | Structural characterization and antioxidant activity of a novel heteropolysaccharide from the submerged fermentation mycelia of Ganoderma capense显示文摘 | Huang Yating Li Naisheng Wan Jianbo | 2015 | Carbohydrate Polymers2015，134，： | 1 |
| 3 | Electrically pumped quantum-dot lasersgrownon 300 mm patterned Si photonic wafers显示文摘Monolithic integration of quantum dot(QD)gain materials onto Si photonic platforms via direct epitaxial growth is a promising solution for on-chip light sources.Recent developments have demonstrated superior device reliability in blanket hetero-epitaxy ofⅡ-Ⅴdevices on Si at elevated temperatures.Yet,thick,defect management epi designs prevent vertical light coupling from the gain region to the Si-on-lnsulator waveguides.Here,we demonstrate the frst electrically pumped QD lasers grown by molecular beam epitaxy on a 300 mm patterned(001)Si wafer with a buttcoupled configuration.Unique growth and fabrication challenges imposed by the template architecture have been resolved,contributing to continuous wave lasing to 60℃and a maximum double-side output power of 126.6 mW at 20℃with a double-side wall-plug efficiency of 8.6%.The potential for robust on-chip laser operation and effcient lowloss light coupling to Si photonic circuits makes this heteroepitaxial integration platform on Si promising for scalable and low-cost mass production. | Chen Shang Kaiyin Feng Eamonn THughes Andrew Clark Mukul Debnath Rosalyn Koscica Gerald Leake Joshua Herman David Harame Peter Ludewig Yating Wan John E.Bowers | 2022 | Light(Science & Applications)2022，11，11： | 1 |
| 4 | Metal–ligand interfaces for well-defined gold nanoclusters显示文摘Ligand engineering for well-defined gold nanoclusters(Au NCs) is getting more extensive attention. Organizing the Au-ligand interfaces on gold NCs can achieve the structural and functional control. This review focuses on the Au-ligand interfaces including gold-phosphorus(Au-P), gold-sulfur(Au-S), gold-selenium(Au-Se), gold-carbon(Au-C), and gold-nitrogen(Au-N), derived from the bonding between Au atoms and the different ligands(e.g., organic phosphine, thiolate, selenolate, alkynyl,n-heterocyclic carbene and nitrogenous ligands). The formation mechanism of Au-ligand interfaces is well discussed. In addition, the effects of Au-ligand interfaces on the stability, optical property, and catalysis are also presented. We hope the advances in this research area can boost the development of Au NC sciences. | Dan Yang Yating Wu Zhaotong Yuan Chunmei Zhou Yihu Dai Xiaoyue Wan Yan Zhu Yanhui Yang | 2024 | Science China Chemistry2024，67，3： | 0 |
| 5 | Interplays between drugs and the gut microbiome显示文摘The gut microbiota is considered a key‘metabolic organ’.Its metabolic activities play essential roles complementary to the host metabolic functions.The interplays between gut microbes and commonly used non-antibiotic drugs have garnered substantial attention over the years.Drugs can reshape the gut microorganism communities and,vice versa,the diverse gut microbes can affect drug efficacy by altering the bioavailability and bioactivity of drugs.The metabolismof drugs by gut microbial action or by microbiota–host cometabolism can transform the drugs into various metabolites.Secondary metabolites produced from the gut microbial metabolismof drugs contribute to both the therapeutic benefits and the side effects.In view of the significant effect of the gut microbiota on drug efficiency and clinical outcomes,it is pivotal to explore the interactions between drugs and gut microbiota underlying medical treatments.In this review,we describe and summarize the complex bidirectional interplays between gut microbes and drugs.We also illustrate the gut-microbiota profile altered by non-antibiotic drugs,the impacts and consequences of microbial alteration,and the biochemical mechanism of microbes impacting drug effectiveness.Understanding how the gut microbes interact with drugs and influence the therapeutic efficacy will help in discovering diverse novel avenues of regulating the gut microbes to improve the therapeutic effects and clinical outcomes of a drug in precision. | Yating Wan Tao Zuo | 2022 | Gastroenterology Report2022，10，1： | 0 |
| 6 | Silicon photonics for high-capacity data communications显示文摘In recent years,optical modulators,photodetectors,(de)multiplexers,and heterogeneously integrated lasers based on silicon optical platforms have been verified.The performance of some devices even surpasses the traditional III-V and photonic integrated circuit(PIC)platforms,laying the foundation for large-scale photonic integration.Silicon photonic technology can overcome the limitations of traditional transceiver technology in high-speed transmission networks to support faster interconnection between data centers.In this article,we will review recent progress for silicon PICs.The first part gives an overview of recent achievements in silicon PICs.The second part introduces the silicon photonic building blocks,including low-loss waveguides,passive devices,modulators,photodetectors,heterogeneously integrated lasers,and so on.In the third part,the recent progress on high-capacity silicon photonic transceivers is discussed.In the fourth part,we give a review of high-capacity silicon photonic networks on chip. | YAOCHENG SHI YONG ZHANG YATING WAN YU YU YUGUANG ZHANG XIAO HU XI XIAO HONGNAN XU LONG ZHANG BINGCHENG PAN | 2022 | Photonics Research2022，10，9： | 0 |
| 7 | A visual analysis approach for data imputation via multi-party tabular data correlation strategies显示文摘Data imputation is an essential pre-processing task for data governance,aimed at filling in incomplete data.However,conventional data imputation methods can only partly alleviate data incompleteness using isolated tabular data,and they fail to achieve the best balance between accuracy and eficiency.In this paper,we present a novel visual analysis approach for data imputation.We develop a multi-party tabular data association strategy that uses intelligent algorithms to identify similar columns and establish column correlations across multiple tables.Then,we perform the initial imputation of incomplete data using correlated data entries from other tables.Additionally,we develop a visual analysis system to refine data imputation candidates.Our interactive system combines the multi-party data imputation approach with expert knowledge,allowing for a better understanding of the relational structure of the data.This significantly enhances the accuracy and eficiency of data imputation,thereby enhancing the quality of data governance and the intrinsic value of data assets.Experimental validation and user surveys demonstrate that this method supports users in verifying and judging the associated columns and similar rows using theirdomain knowledge. | Haiyang ZHU Dongming HAN Jiacheng PAN Yating WEI Yingchaojie FENG Luoxuan WENG Ketian MAO Yuankai XING Jianshu LV Qiucheng WAN Wei CHEN | 2024 | Frontiers of Information Technology & Electronic Engineering2024，25，3： | 0 |
| 8 | Erratum to: A visual analysis approach for data imputation via multi-party tabular data correlation strategies显示文摘 | Haiyang ZHU Dongming HAN Jiacheng PAN Yating WEI Yingchaojie FENG Luoxuan WENG Ketian MAO Yuankai XING Jianshu LV Qiucheng WAN Wei CHEN | 2024 | Frontiers of Information Technology & Electronic Engineering2024，25，3： | 0 |
| 9 | Light people:Prof.Evelyn Hu's adventure:from semiconductors to quantum-from industry to academia显示文摘Editorial As part of our Light People series,we are delighted to have invited Prof.Evelyn Hu,a highly accomplished scientist from Harvard University,to share with us her personal journey.Prof.Hu's remarkable contributions in both academia and industry have taken her from industry giants to academia's most prestigious institutions,traversing various research frontiers that have played a critical role in the ongoing digital revolution.Through this interview,we aim to offer the Light community valuable insights into nanophotonics,quantum engineering,and Prof.Hu's research methodology and life philosophy,while also celebrating her outstanding achievements as a female role model.Ultimately,our goal is to inspire more women to pursue careers in this important and rapidly expanding field,which has a profound impact on all sectors of society.The following is a summary of an interview with Professor Evelyn Hu,available in the Supplementary Information. | Yating Wan Chenzi Guo | 2023 | Light(Science & Applications)2023，12，8： | 0 |
| 10 | Atomically Precise Water-Soluble Gold Nanoclusters:Synthesis and Biomedical Application显示文摘Atomically precise water-soluble gold nanoclusters(Au NCs)protected by organic ligands have attracted growing attention in serving as unique nanomaterials with the potential to generate theranostic tools(bioimaging,biosensing,and biotherapy),due to their ultrasmall size,superior photoluminescence,good biocompatibility,and nontoxicity.More importantly,Au NCs afford a well-defined atomic packing structure and molecular purity,providing a superior platform to unravel the structure−performance correlations for biodistribution,biological pharmacokinetics,and excretion of Au NCs.In this Review,we mainly survey the synthesis of water-soluble Au NCs and the recent progress in biomedicine of Au NCs,including bioimaging,biosensing,and biotherapy.The effects of ligand and size on the biomedical properties are discussed in detail.We hope that the advances in this research area can expand the applications of Au NCs in biomedicine. | Qian Yan Zhaotong Yuan Yating Wu Chunmei Zhou Yihu Dai Xiaoyue Wan Dan Yang Xu Liu Nianhua Xue Yan Zhu Yanhui Yang | 2023 | Precision Chemistry2023，1，8： | 0 |
| 11 | Linewidth narrowing in self-injection-locked on-chip lasers显示文摘Stable laser emission with narrow linewidth is of critical importance in many applications,including coherent communications,LIDAR,and remote sensing.In this work,the physics underlying spectral narrowing of self-injection-locked on-chip lasers to Hz-level lasing linewidth is investigated using a composite-cavity structure.Heterogeneously integrated III–V/SiN lasers operating with quantum-dot and quantum-well active regions are analyzed with a focus on the effects of carrier quantum confinement.The intrinsic differences are associated with gain saturation and carrier-induced refractive index,which are directly connected with 0-and 2-dimensional carrier densities of states.Results from parametric studies are presented for tradeoffs involved with tailoring the linewidth,output power,and injection current for different device configurations.Though both quantum-well and quantum-dot devices show similar linewidth-narrowing capabilities,the former emits at a higher optical power in the self-injection-locked state,while the latter is more energy-efficient.Lastly,a multi-objective optimization analysis is provided to optimize the operation and design parameters.For the quantum-well laser,minimizing the number of quantum-well layers is found to decrease the threshold current without significantly reducing the output power.For the quantum-dot laser,increasing the quantum-dot layers or density in each layer increases the output power without significantly increasing the threshold current.These findings serve to guide more detailed parametric studies to produce timely results for engineering design. | Emad Alkhazraji Weng W.Chow Frédéric Grillot John E.Bowers Yating Wan | 2023 | Light(Science & Applications)2023，12，10： | 0 |
| 12 | Multi-omic analyses identify mucosa bacteria and fecal metabolites associated with weight loss after fecal microbiota transplantation显示文摘Fecal microbiota transplantation(FMT)has shown promising results in animal models of obesity,while results in human studies are inconsistent.We aimed to determine factors associated with weight loss after FMT in nine obese subjects using serial multi-omics analysis of the fecal and mucosal microbiome.The mucosal microbiome,fecal microbiome,and fecal metabolome showed individual clustering in each subject after FMT.The colonic microbiome in patients showed more marked variance after FMT compared with the duodenal microbiome,characterized by an increased relative abundance of Bacteroides.Subjects who lost weight after FMT sustained enrichment of Bifidobacterium bifidum and Alistipes onderdonkii in the duodenal,colonic mucosal,and fecal microbiome and increased levels of phosphopantothenate biosynthesis and fecal metabolite eicosapentaenoic acid(EPA),compared with those without weight loss.Fecal levels of amino acid metabolism-associated were positively correlated with the fecal abundance of B.bifidum,and fatty acid metabolism-associated metabolites showed positive correlations with A.onderdonkii. | Fen Zhang Tao Zuo Yating Wan Zhilu Xu Chunpan Cheung Amy YLi Wenyi Zhu Whitney Tang Paul K.S.Chan Francis K.L.Chan Siew C.Ng | 2022 | The Innovation2022，3，5： | 0 |
| 13 | Nonlinear optical metal-organic frameworks for ratiometric temperature sensing in physiological range显示文摘The precise and real-time sensing of the temperature within the physiological range is of great significance in biology and medicine.Here,a Zn-based metal-organic framework(MOF)named ZnTCOMA is synthesized with good SHG performance due to its unique structure of the ligand and 3 D frameworks.By encapsulating the two-photon fluorescent dye DMASE into the pores of Zn-TCOMA,the composite Zn-TCOMA■DMASE is obtained and simultaneously exhibits SHG response and two-photon fluo rescence.Utilizing the intensity ratio between two-photon fluorescence of DMASE and SHG signal of Zn-TCOMA,Zn-TCOMA■DMASE exhibits ratiometric temperature sensing property at physiological temperature region of 20~60℃with high sensitivity.This MOF thermometer also shows excellent repeatability,good biocompatibility,and high temperature resolution of 0.018℃,opening a new avenue to develop diverse optical thermometric or thermographic applications in biotechnology or other areas. | Yating Wan Yuanjing Cui Yu Yang Guodong Qian | 2021 | Chinese Chemical Letters2021，32，4： | 0 |
| 14 | 25-year-old Bao has 3 generations显示文摘Strong and healthy,Bao selected for captive breeding The Tian-e-zhou Bajji National Nature Reserve in Shishou City of Hubei province is the first ex-situ conservation area for cetacea in the world.In 1990,five Yangtze finless porpoises were relocated there.In 1996,the Institute of Hydrobiology of Chinese Academy of Sciences started to raise Yangtze finless porpoises.There were only one male and two female porpoises and no baby ones there for a very long time. | Gao Baoyan Wan Xiooling Huang Yating Gan Juan | 2022 | Changjiang Weekly2022，，27： | 0 |
| 15 | Light People:Prof.John Bowers spoke about silicon photonics显示文摘Editorial Silicon photonics is advancing rapidly with many scientific and engineering advances and many new applications for photonics.To highlight the topic,Light:Science&Applications invited John Bowers,director of the Institute for Energy Efficiency and distinguished professor from the University of California,Santa Barbara,to talk about the fundamentals and industries,and give a future perspective of silicon photonics.The below is summarized from the video interview of Prof.Bowers.The original interview can be accessed in Supplementary video. | Chenzi Guo Yating Wan | 2022 | Light(Science & Applications)2022，11，12： | 0 |
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