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| 1 | Nano-tribological properties and mechanisms of the liquid crystal as an additive显示文摘Under conditions of low speed, small viscosity and molecularly smooth tribe-surfaces, the behavior of lubricant film in the nano scale is different from that in elas-tohydrodynamic lubrication (EHL) and boundary lubrication (BL). Due to the size effect, long-range ordered structure of liquid crystal (LC) has great effects on the tribological properties and film-forming mechanism of thin film in the nano scale. The technique of relative optical interference intensity (ROII) was used to investigate nano-tribological properties when cholesteryl LCs are added to hexadecane. The results indicate that the practical film thickness of hexadecane with liquid crystal is 3-5 times as large as that expected from EHL theory in the low speed region. The film thickness increases with the enhancement in polarity and concentration of LC in hexadecane, and external DC voltage. The effective viscosity of lubricant is related to the film thickness and the voltage and it varies from bulk viscosity to several times or tens | Mingwu Shen Jianbin Luo Shizhu Wen Junbin Yao | 2001 | Chinese Science Bulletin2001，46，14： | 8 |
| 2 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 3 | Improvement of Hydrolytic Stability of Borate Esters Used as Lubricant Additives 显示文摘 | Yao Junbin Dong Junxiu | 1995 | L ubrication Engineering1995，51，6： | 1 |
| 4 | Evaluation of alkali metal salts as deposit inhibitors for synthetic lubricants by differential scanning calorimetry (DSC)显示文摘 | Yao Junbin | 1997 | Thermochimica Acta1997，，1： | 1 |
| 5 | Evaluation of sodium acetylacetonate as a synergist for arylamine antioxidants in synthetic lubricants显示文摘 | Junbin Yao | 1997 | Tribology International1997，，11： | 1 |
| 6 | Improvement of hydrolytic stability of borate esters used as lubricant additives显示文摘 | | 1995 | Lubr Eng1995，51，6： | 1 |
| 7 | Improvement of hydrolytic stability of borate esters used as lubricant additives显示文摘 | Yao Junbin Dong J unxiu | 1995 | Lubric Eng1995，51，6： | 1 |
| 8 | Improvement of hydrolytic stability of borate esters used as lubricant additives 显示文摘 | Yao Junbin | 1995 | Lubr Eng1995，51，6： | 1 |
| 9 | Improvement of hydrolytic stability of borate esters used as lubricant additives 显示文摘 | Yao Junbin | 1995 | Lubr Eng1995，51，6： | 1 |
| 10 | Improvement of hydrolytic stability of borate esters used as lubricant additives显示文摘 | Yao Junbin Dong Junxiu | 1995 | Lubric Eng1995，51，6： | 1 |
| 11 | Antiwear function and mechanism of borate containing nitrogen显示文摘 | YAO Junbin | 1997 | Tribology International1997，30，6： | 1 |
| 12 | Improvement of Hydrolytic Satbility of Borate Esters Used as Lubricant Additives 显示文摘 | YAO Junbin DONG Junxiu | 1995 | LubrEng1995，51，6： | 1 |
| 13 | Improvement of Hydrolyt- ic Stability of Borate Esters Used as Lubrieant Addi- tives 显示文摘 | Yao Junbin Dong Junxiu | 1995 | Lubric Eng1995，51，6： | 1 |
| 14 | Antiwear Function and Mechanism of Borate Containing Nitrogen显示文摘 | Yao Junbin | 1997 | Tribology International1997，30，6： | 1 |
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