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您的检索式：作者名="Yanxia Nie"
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| 1 | Reprogramming of phytopathogen transcriptome by a non-bactericidal pesticide residue alleviates its virulence in rice显示文摘Bacteria equipped with virulence systems based on highly bioactive small molecules can circumvent their host's defense mechanisms.Pathogens employing this strategy are currently threatening global rice production.In the present study,variations in the virulence of the highly destructive Barkholderiaplantarii were observed in different rice-producing regions.The environment-linked variation was not attributable to any known host-related or external factors.Co-occurrence analyses indicated a connection between reduced virulence and 5-Amino-l,3,4-thiadiazole-2-thiol(ATT),a non-bactericidal organic compound.ATT,which accumulates in rice plants during metabolization of specific agrochemicals,was found to reduce virulence factor secretion by B.plantarii up to 88.8%and inhibit pathogen virulence by hijacking an upstream signaling cascade.Detailed assessment of the newly discovered virulence inhibitor resulted in mechanistic insights into positive effects of ATT accumulation in plant tissues.Mechanisms of virulence alleviation were deciphered by integrating high-throughput data,gene knockout mutants,and molecular interaction assays.TroK,a histidine protein kinase in a two-component system that regulates virulence factor secretion,is likely the molecular target antagonized by ATT.Our findings provide novel insights into virulence modulation in an important plant-pathogen system that relies on the host's metabolic activity and subsequent signaling interference. | Haruna Matsumoto Yuan Qian Xiaoyan Fan Sunlu Chen Yanxia Nie Kun Qiao Dandan Xiang Xinzhong Zhang Meng Li Bo Guo Peilin Shen Qiangwei Wang Yunlong Yu Tomislav Cemava Mengcen Wang | 2022 | Fundamental Research2022，2，2： | 2 |
| 2 | Key Construction Technology of Ultra-deep Diaphragm Wall Under Complicated Geological Conditions显示文摘The LNG Receiving Station project in Shenzhen is located in a land reclamation area with complicated geological conditions.The thickness of diaphragm wall is 1.5 m,the depth is up to 62 m,and is extremely difficult to construct.During the construction process,slot wall reinforcement technology is used to ensure the stability of slot formation,and milling-drilling-milling technology is used to address the problem of ultra-deep rock of diaphragm wall.The super-large reinforcement cage of underground continuous wall is built and lifted in one time to ensure the construction quality and safety,and the green construction is achieved by adopting the green and environment-friendly mud circulation treatment technology.The construction technology of ultra-deep diaphragm wall applied in the project yielded positive results and has the potential be become more widely used. | SHI Jiangchuan LIU Weiwei CHENG Peichun NIE Yanxia ZHU Haobo XIE Zhicheng | 2022 | 施工技术(中英文)2022，51，9： | 0 |
| 3 | Key Construction Technology of Super Large Diaphragm Wall Reinforcement Cage显示文摘The longest reinforcement cage of the Shenzhen LNG Receiving Station’s underground continuous wall is 59.5 m,and the total lifting weight is more than 110 t.It is a super large reinforcement cage,which is extremely tough to construct and lift.The quality of reinforcement cage processing is guaranteed by adopting the mold frame and a reasonable processing procedure.Feasible technical scheme and quality and safety assurance measures are put forward from the aspects of site layout,hoisting equipment selection,hoisting point layout and hoisting process control to ensure the safe implementation of super large underground continuous wall reinforcement cage hoisting operation.Combined with the project example,the construction challenge of super large underground continuous wall reinforcement cage is solved by adopting the construction technology of integral fabrication and hoisting. | SHI Jiangchuan LIU Weiwei NIE Yanxia CHENG Peichun | 2022 | 施工技术(中英文)2022，51，9： | 0 |
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