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您的检索式：作者名="Yanting Lyu"
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| 1 | Type I photosensitizer based on AIE chromophore tricyano-methylene-pyridine for photodynamic therapy显示文摘Image guided photodynamic therapy(PDT)combines fluorescence tracing and phototherapy,which can achieve a more accurate and effective treatment effect.However,traditional photosensitizers are limited by the aggregation-caused fluorescence quenching(ACQ)effect and low reactive oxygen species(ROS)generation in a hypoxic environment,resulting in poor imaging and treatment effect.Herein,we report a tricyano-methylene-pyridine(TCM)-based Type I aggregation-induced emission(AIE)photosensitizer(TCM-MBP),the strong elec-tron acceptance(D-A)effect extends the wavelength to near-infrared(NIR)region to reduce the autofluorescence interference,and oxygen atoms provide lone pair electrons to enhance the inter system crossing(ISC)rate,thereby promoting the generation of more triplet states to produce ROS.The AIE photosensitizer TCM-MBP exhibited low oxygen dependence,NIR emission,and higher ROS production compared to commercially avail-able Ce_(6) and RB.After encapsulation with DSPE-PEG 2000,TCM-MBP nanoparticles(TCM-MBP NPs)could penetrate to visualize cells and efficiently kill cancer cells upon light irradiation.This study provides an oxygen-independent AIE photosensitizer,which has great potential to replace the commercial ACQ photosensitizers. | Chao Pan Weijun Zhao Xiaolei Zhao Zhenxing Liu Xiangyu Li Yanting Lyu Xupeng Wu Zhirong Zhu Wei-Hong Zhu Qi Wang | 2023 | Green Chemical Engineering2023，4，3： | 0 |
| 2 | Purification and characterization of a trypsin inhibitor from the seeds of Artocarpus heterophyllus Lam显示文摘对胰岛素的一个 proteinaceous 禁止者从 Artocarpus heterophyllus 的种子被孤立打。由连续的铵硫酸盐降水,离子交换,和胶化过滤层析。胰岛素禁止者,作为 AHLTI 说出(一。heterophyllus 打。胰岛素禁止者) ,与 28.5 kDa 的分子的重量由单个多肽链组成了,它被钠 dodecyl sulfatepolyacrylamide 胶化电气泳动和胶化过滤层析证实。AHLTI 的 N 终端顺序是 DEPPSELDAS,它没显示出类似到另外的已知的胰岛素禁止者顺序。AHLTI 完全在本国的 polyacrylamide 胶化电气泳动,抑制活动试金,和胶化过滤层析分析的 1:2 (AHLTI:trypsin ) 的臼齿的比率禁止了牛的胰岛素。而且,运动酶的研究被执行对胰岛素理解 AHLTI 的抑制机制。结果证明 AHLTI 是有一个平衡分离常数的一个竞争禁止者(K 3.7 的 i ) 吗?? | Junchen Lyu Yuan Liu Tianchen An Yujun Liu Manchuriga Wang Yanting Song Feifei Zheng Dan Wu Yingxia Zhang Shiming Deng | 2015 | Acta Biochimica et Biophysica Sinica2015，47，5： | 0 |
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