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| 1 | Efficacy and advantages of modified Traditional Chinese Medicine treatments based on'kidney reinforcing'for chronic aplastic ane-mia:a randomized controlled clinical trial显示文摘OBJECTIVE:To compare the efficacy of modified treatments based on 'kidney reinforcing' in the management of chronic aplastic anemia(CAA),and explore their advantages and specialties.METHODS:One hundred and eleven patients with CAA were randomly divided into three groups:kidney reinforcing alone(KA),'kidney reinforcing and Qi tonifying'(KQ),and 'kidney reinforcing and blood circulation invigorating'(KC).Normal and positive control groups were also formed.All patients were treated for 6 months(two courses).Hemograms,Traditional Chinese Medicine(TCM) syndrome scores,and therapeutic effects were assessed,and changes in T-lymphocyte subsets,regulatory T cells and cytokines were detected.RESULTS:The KQ and KC groups had lower TCM syndrome scores than the positive control group after 6 months(P < 0.05).The KQ group had a higher overall efficacy than the positive control group after 3 months(P < 0.05),while platelet counts increased in the KC group after 6 months(P < 0.05).CD3+ T-lymphocyte ratios decreased only in the KQ group,while CD3 + CD4 + CD8-Tlymphocytes increased only in the KC group after 6 months(P <0.05).Levels of interferon-γ,tumor necrosis fac-tor-α,interleukin(IL)-2 and IL-6 decreased and levels of IL-4 and IL-10 increased in all treated groups after 6 months.Levels of IL-6 in the KQ and KC groups were lower than those in the positive control group(P < 0.05).CONCLUSION:Treatments based on kidney reinforcing have a rebalancing effect on cytotoxic and T helper cells,and regulate expression of interferon-γ,IL-2,IL-6 and IL-4.KQ may be more effective in treating CAA,and KC may have an advantage in platelet recovery. | Wu Dijiong Shen Yiping Ye Baodong Fang Bingmu Lin Shengyun Chen Zhilu Jiang Huifang Feng Changwei He Lüyuan Gao Yanting Liu Yonglin Liu Yonghua Zhu Jiajia Wu Liqiang Shao Keding Zhou Yuhong | 2016 | Journal of Traditional Chinese Medicine2016,36,4: | 6 |
| 2 | Synthesis, characteristics of hierarchical EU-1 zeolite for xylene isomerization probe reaction显示文摘Introduced a method of synthesizing hierarchical EU-1 zeolite with organosilanes as additive, and studied the influences of following different kinds of organosilanes on the synthesis of hierarchical EU-1 zeolite: γ-glycidoxy propyl trimethoxy silane(GPTMS), N-β-(aminoethyl)-γ-aminopropyl methyl dimethoxyl silane(APAEDMS),and N-(β-aminoethyl)-γ-aminopropyl dimethoxyl(ethyoxyl) silane(TMPED). The hierarchical EU-1 samples were characterized by XRD, SEM, N_2 adsorption, FT-IR and NH_3-TPD to analyze the crystallinity, morphology, surface area, pore size distribution and acidity. The results showed that hierarchical EU-1 zeolites were successfully synthesized; organosilanes have great influence on crystal morphology of EU-1 zeolites; the exterior surface area of hierarchical EU-1 zeolite, which synthesized with organosilanes(APAEDMS) adding into synthesis system, increased by 62.1% and mesopore volume increased by 129.1% compared with conventional EU-1 zeolites, thus can reduce the diffusional restriction markedly in catalytic reaction. The catalytic performance of hierarchical EU-1zeolites were evaluated in m-xylene isomerization on fixed bed reactor. The catalytic data showed that the isomerization activity PX/X of the hierarchical EU-1 zeolites reached around 24.09% in theoretical thermodynamic equilibrium from 23.83%, and the selectivity of C_8 aromatic hydrocarbon increased from 75.16% to 84.87%. The conversion of p-xylene increased from 16.30% to 18.41%. | Xiaofeng Li Pengchao Ren Yanting Zhang Xiaozhen Liu Xiaotao Sun Meng Gao Miaojuan Jia Zhiping Lü Tao Dou | 2016 | Chinese Journal of Chemical Engineering2016,24,11: | 4 |
| 3 | Photoeatalysis on TiO2 surfaces: principles, mechanisms, and selected results 显示文摘 | Linsehigler A L Lu G Yantes J T | 1995 | Chem Rev1995,95,: | 1 |
| 4 | The selenoprotein PHGPx is essential for mmuse development and protects from radiation and oxidative damage insults显示文摘 | Yant L J Ran Q Rao L | | 0,,04: | 1 |
| 5 | Helper-independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo 显示文摘 | Mikkelsen JG Yant SR Meuse L | 2003 | MolTher2003,8,4: | 1 |
| 6 | Somatic integration and longterm transgene expression in normal and haemophilic mice using a DNA transposon system显示文摘 | Yant SR Meuse L Chiu W | 2000 | Nat Genet2000,25,1: | 1 |
| 7 | Repression of flowering bythe miR172 target SMZ显示文摘 | MATHIEU J YANT L J MRDTER F | 2009 | PLoS Biology2009,7,7: | 1 |
| 8 | Repression of flowering by the mi R172 target SMZ显示文摘 | MATHIEU J YANT L J MRDTER F | 2007 | PLo S Biology2007,7,10: | 1 |
| 9 | The selenoprotein GPX4 is essen- tial for mouse development and protects from radiation and oxidative damage insults显示文摘 | YANT L J RAN Q RAO L | 2003 | Free Radic Biol Med2003,34,4: | 1 |
| 10 | Formation of CdS Nanoparticles Within Modified MCM-41 and SBA-15 显示文摘 | Xu Wei Liao Yanting Akins D L | 2002 | J Phys Chem B2002,106,11: | 1 |
| 11 | Helper-independent Sleeping Beauty transposon-transposase vectors for efficient non-viral gene delivery and persistent gene expression in vivo显示文摘 | Mikkelsen J Yant S Meuse L | 2003 | Mol Ther2003,8,4: | 1 |
| 12 | Meiotic adaptation to genome duplication in Arabidopsis arenosa 显示文摘 | YANT L HOLLISTER J D WRIGHT K M | 2013 | Current Biology2013,23,21: | 1 |
| 13 | The end of innocence: Flowering networks explode in complexity显示文摘 | Pose D Yant L Sehmid M | 2012 | Current Opinion in Plant Biology2012,45,: | 1 |
| 14 | Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system 显示文摘 | Yant S R Meuse L Chiu W | 2000 | Nature Genetics2000,25,1: | 1 |
| 15 | Formation of CdS nanoparticles within modified MCM-41 and SBA 15 显示文摘 | Xu Wei Liao Yanting Daniel L A | 2002 | Journal of Physical Chemistry B2002,106,11: | 1 |
| 16 | Orchestration of the floral transition and floral development in Arabidopsis by the bifunctional transcription factor APETALA2 显示文摘 | YANT L MATHIEU J DINH T T | 2010 | The Plant Cell2010,22,7: | 1 |
| 17 | Control of SIVmac239 is not predicted by inheritance of Mamu-B * 17- containing haplotypes 显示文摘 | Jason A W Yant L J Wiseman R W | 2007 | J Virol2007,81,: | 1 |
| 18 | Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response 显示文摘 | Friedrich T C Frye C A Yant L J | 2004 | J Virol2004,78,: | 1 |
| 19 | Reversion of CTL escape-variant immunodeficiency viruses in vivo 显示文摘 | Friedrich T C Dodds E J Yant L J | 2004 | Nature Med2004,10,: | 1 |
| 20 | The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults显示文摘 | YANT LJ RAN Q RAO L | 2003 | Free Radic Biol Med2003,,34: | 1 |