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| 1 | Darwin:a neuromorphic hardware co-processor based on Spiking Neural Networks显示文摘Broadly speaking, the goal of neuromorphic engineering is to build computer systems that mimic the brain. Spiking Neural Network(SNN) is a type of biologically-inspired neural networks that perform information processing based on discrete-time spikes, different from traditional Artificial Neural Network(ANN).Hardware implementation of SNNs is necessary for achieving high-performance and low-power. We present the Darwin Neural Processing Unit(NPU), a neuromorphic hardware co-processor based on SNN implemented with digitallogic, supporting a maximum of 2048 neurons, 20482= 4194304 synapses, and 15 possible synaptic delays.The Darwin NPU was fabricated by standard 180 nm CMOS technology with an area size of 5 × 5 mm2and70 MHz clock frequency at the worst case. It consumes 0.84 m W/MHz with 1.8 V power supply for typical applications. Two prototype applications are used to demonstrate the performance and efficiency of the hardware implementation. | Juncheng SHEN De MA Zonghua GU Ming ZHANG Xiaolei ZHU Xiaoqiang XU Qi XU Yangjing SHEN Gang PAN | 2016 | Science China(Information Sciences)2016，59，2： | 18 |
| 2 | Detection of nanobacteria in serum, bile and gallbladder mucosa of patients with cholecystolithiasis显示文摘In 1990, nanobacterium was found and named by Kajander.1 With distinct mineralizing ability, nanobacteria are thought to play a role in extraskeletal calcifying diseases. It have been found in many human tissues, but whether they exist in the bile or gallbladder mucosa remains unclear. The present study was undertaken to investigate by ELISA, bacterial culturing, immunohistochemical staining and transmission electron microscopy (TEM), whether nanobacteria exist in serum, bile or gallbladder mucosa of healthy people and patients with cholecystolithiasis. | WENYu LIYong-guo YANGZhu-lin WANGXue-jun WEIHong LIUWei MIAOXiong-ying WANGQun-wei HUANGSheng-fu YANGJing E.OlaviKajander NevaCiftcioglu | 2005 | Chinese Medical Journal2005，，5： | 15 |
| 3 | Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment显示文摘The failure of a massive influx of tumor-infiltrating T lymphocytes to eradicate tumor cells in the tumor microenvironment is mainly due to the dysfunction of T cells hyporesponsive to tumors.T-cell exhaustion and senescence induced by malignant tumors are two important dysfunctional states that coexist in cancer patients,hindering effective antitumor immunity and immunotherapy and sustaining the suppressive tumor microenvironment.Although exhausted and senescent T cells share a similar dysfunctional role in antitumor immunity,they are distinctly different in terms of generation,development,and metabolic and molecular regulation during tumor progression.Here,we discuss the unique phenotypic and functional characteristics of these two types of dysfunctional T cells and their roles in tumor development and progression.In addition,we further discuss the potential molecular and metabolic signaling pathways responsible for the control of T-cell exhaustion and senescence in the suppressive tumor microenvironment.Understanding these critical and fundamental features should facilitate rethinking the unresponsiveness to current immunotherapies in clinical patients and lead to further development of novel and effective strategies that target different types of dysfunctional T cells to enhance cancer immunotherapy. | Yangjing Zhao Qixiang Shao Guangyong Peng | 2020 | Cellular & Molecular Immunology2020，17，1： | 11 |
| 4 | Electrolyte Optimization of Microarc Oxidation of Magnesium Alloy显示文摘Magnesium alloy AZ91D was processed respectively in one, two, three and four-component electrolytes by using AC microarc oxidation technique. The corrosion resistance of AZ91D alloy was measured by electrochemical methods. The optimum electrolytes in two, three and four components were found. In four-component electrolyte composed by NaOH, NaAlOj, H2O2 and C4H4O6N32, the film formed on AZ91D alloy is smooth and compact, and has a higher corrosion resistance. The effect of the ingredients in electrolytes was discussed based on their roles in the formation of corrosion resistant film. | FANGDa-ran WANGJi-hui YANGJing | 2004 | 材料热处理学报2004，25，05B： | 6 |
| 5 | Characterization,virulence,and genetic variation of Rhizoctoria solani Ag-9 in Alberta显示文摘 | YANGJ KHARBANDAPD WANGH etal | 1996 | Plant Disease1996，80，： | 2 |
| 6 | Raman and FTIR spectroscopy of natural oxalates: Implications for the evidence of life on Mars显示文摘Evidence for the existence of primitive life forms such as lichens and fungi can be based upon the for-mation of oxalates. Oxalates are most readily detected using Raman spectroscopy. A comparative study of a suite of natural oxalates including weddellite, whewellite, moolooite, humboldtine, glushinskite, natroxalate and oxammite has been undertaken using Raman spectroscopy. The minerals are characterised by the Raman position of the CO stretch-ing vibration which is cation sensitive. The band is observed at 1468 cm-1 for weddellite, 1489 cm-1 for moolooite, 1471 cm-1 for glushinskite and 1456 cm-1 for natroxalate. Except for oxammite, the infrared and Raman spectra are mutually exclusive indicating the minerals are bidentate. Differences are also observed in the water OH stretching bands of the minerals. The significance of this work rests with the ability of Raman spectroscopy to identify oxalates which often occur as a film on a host rock. As such Raman spectroscopy has the potential to identify the existence or pre-existence of life forms on planets such as Mars. | R.L.Frost YANGJing ZheDing | 2003 | Chinese Science Bulletin2003，48，17： | 2 |
| 7 | Heavy metal adsorption by a formulated zeolite-Portland cement mixture 显示文摘 | Ok Y S YangJ E Zhang Y S | 2007 | Journal of Hazardous Materials2007，147，12： | 1 |
| 8 | MicroRNA -451 func- tions as a tumor suppressor in human non - small cell hlng cancer by targeting ras - related protein 14 (RAB14) 显示文摘 | WANG R WANGZ X YANGJ S | 2011 | Oncogene2011，30，23： | 1 |
| 9 | One pot synthesis of potassium-Iunctionalized mesoporousy-alumina , a solid superbase显示文摘 | SUN Lin-bing YANGJing KOUJia-huivez al | 2008 | Angewandte Chemie2008，120，18： | 1 |
| 10 | 显示文摘 | LiuL LiuZ YangJ etal | 2007 | Carbon2007，45，14： | 1 |
| 11 | Size and com-position tunable Ag-Au alloy nanoparticles by replace-ment reactions显示文摘 | ZHANG Q LEEJ Y YANGJ | 2007 | Nanotechnology2007，18，24： | 1 |
| 12 | Syntheses, Struc- tures and Luminescence of Silver(I) Sulfonate Com- plexeswith PPha Ligand显示文摘 | LIFF MAJ F YANGJ etal | 2006 | J Mol Struct2006，787，： | 1 |
| 13 | Deposition of High Quality of Wurtzite GaN Flims on Cubic (111) MgAl2 O4 Substrates Using Lpmocvd显示文摘 | Sun C J YangJ W Chen Q | 1996 | Appl Phys Lett1996，68，8： | 1 |
| 14 | The Jiamusi Massif:a Jurassic accretionary terrane along the western Pacific margin of NE China显示文摘 | Wu F Y YangJ H Lo C H | 2007 | Island Arc2007，，16： | 1 |
| 15 | TIMP-1 mediates the inhibitory effect of interleukin-6 on the proliferation of H hepatocarcinoma cell line in a STAT3 dependent manner显示文摘 | GuoSY Shen X0 YangJ | 2007 | Braz J Med Biol Res2007，40，5： | 1 |
| 16 | A preference aggregation method through the estimation of utility intervals显示文摘 | Wang Y M YangJ B Xu D 1 | 2005 | Computers & Operations Research2005，32，8： | 1 |
| 17 | Parallel implementation of Katsevich's FBP algorithm显示文摘 | YangJ S Guo X H Kong Q | 2006 | International Journal of Bio medical Imaging2006，2006，17： | 1 |
| 18 | Critical roles of RafiMEK/ERK and PI3 KI AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells显示文摘 | XieJ QianJ YangJ | 2005 | Exp Hematol2005，33，5： | 1 |
| 19 | Image super-resolution via sparse representation显示文摘 | YangJ Wright J Huang T and Ma Y | 2010 | IEEE Transactions on Image Processing2010，19，11： | 1 |
| 20 | Areviewofmethodstocharacterizerubberelasticbehaviorforuseinfiniteelementanalysis显示文摘 | CharltonDJ YangJ TehKK | 1994 | RubberChemistryandTechnol-ogy1994，，67： | 1 |
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