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    题名 作者 年代 出处 被引量
1Causes of death after hip fracture in senile patients显示文摘MARen-shi ZHANGYu HUANGXu ZHUDong GUGui-shan YANGGuo—tao LIMing SONGAi-hua YOUYang 2012Chinese Journal of Traumatology2012,15,1:10
2Quantitative (stereological) study of incomplete spermatogenic suppression induced by testosterone undecanoate injection in rats显示文摘Aim: To evaluate the key lesions in spermatogenesis suppressed partially by testosterone undecanoate(TU) treatment. Methods: Adult male SD rats were treated with vehicle or TU (19 mg/kg) injection (i.m.) every 15 days for 130 days. The numbers of all types of cells (nuclei) in the seminiferous tubules and the interstitial tissue were estimated using a contemporary stereological tool, the optical disector. Results: In response to TU treatment, the numbers of non-type B spermatogonia, type B sperrnatogonia and late elongated spermatids per testis were reduced to 51%, 66% and 14% of the controls, respectively. The conversion ratios from type B spermatogonia to early spermatocytes and pachytene spermatocytes were not significantly affected and the ratios to the later germ cell types fell to 51%-65% of the controls. Less than 1.0 % of immature round spermatids were seen sloughing into the tubule lumen, 4.0% of elongated spermatids retained in the seminiferous epithelium, and about half of the elongated spermatid nuclei appreciably malformed. Leydig cells were atrophied but their number and the peritubular myoid cell number per testis were unchanged. Conclusion: Double inhibition of spermatogenesis (i.e. inhibition at spermiation and spermatogonial conversion to type B spermatogonia), a scenario seen in the monkey and human following gonadotrophin withdrawal, was not sufficiently effective for a complete spermatogenic suppression in the rat after TU treatment, probably due to ineffective inhibition of the Leydig cell population and therefore the intra-testicular test-osterone levels. (Asian J Androl 2004 Dec; 6: 291-297)Zheng-WeiYang YangGuo LiLin Xing-HaiWang Jian-SunTong Gui-YuanZhang 2004Asian Journal of Andrology2004,6,4:9
3Preparation of Clay/Biochar Composite Adsorption Particle and Performance for Ammonia Nitrogen Removal from Aqueous Solution显示文摘This study aimed to present a novel clay/biochar composite adsorption particle, which made from abandoned reed straw and clay to remove ammonia nitrogen(NH4^+-N) from micro-contaminated water. The removal performance of NH4^+-N by composite adsorption particle was monitored under different raw material proportions and initial NH4^+-N concentration. Besides, adsorption kinetics and adsorption isotherms were investigated to reveal the adsorption mechanisms. The results showed that NH4^+-N was effectively removed under optimal proportion of biochar, foaming agent and crosslinker with 20%, 3%, and 3%, respectively. The optimal contact time was 150 min and the best removal efficiency was 88.6% at initial NH4^+-N concentration of 20 mg L^-1. The adsorption performance was well described by the second order kinetic model and Freundlich model. The novel clay/biochar composite adsorption particle in this study demonstrated a high potential for NH4^+-N removal from surface water.HUANG Xiao BAI Jie LI Kuiran ZHAO Yangguo TIAN Weijun HU Chunhui 2020Journal of Ocean University of China2020,19,3:6
4Response of Microbial Community to Petroleum Stress and Phosphate Dosage in Sediments of Jiaozhou Bay, China显示文摘The dynamic microcosms were used to evaluate the effect of oil spills on microbial ecological system in marine sediment and the enhancement of nutrient on the oil removal. The function and structure of microbial community caused by the oil pollution and phosphate dosage were simultaneously monitored by dehydrogenase activity assay and PCR-denaturing gradient gel electrophoresis(DGGE) techniques. The results indicated that the amount of total bacteria in all dynamic microcosms declined rapidly with incubation time. The number of petroleum-degrading bacteria and the activity of sediment dehydrogenase were gradually enhanced by petroleum in the oil-treated microcosms, while they both showed no obvious response to phosphate dosage. In comparison, phosphate spiked heterotrophic bacteria and they showed a significant increase in amount. DGGE profiles indicated that petroleum dosage greatly changed community structure, and the bacteria belonged to class Deltaproteobacteria, and phyla Bacteroidetes and Chlorobi were enriched. This study demonstrated that petroleum input greatly impacted the microbial community structure and consequently the marine sediment petroleum-degrading activity was enhanced. Phosphate dosage would multiply heterotrophic bacteria but not significantly enhance the petroleum degradation.ZHAO Yangguo CHEN Min BAI Jie LI Xinwei Farhana Zulfiqar WANG Qianli 2014Journal of Ocean University of China2014,13,2:4
5Microbial community structure in different wastewater treatment processes characterized by single-strand conformation polymorphism (SSCP) technique显示文摘In order to investigate microbial community structures in different wastewater treatment processes and understand the relationship between the structures and the status of processes,the microbial community diversity,variety and distribution in five wastewater treatment pro cesses were studied by a culture-independent genetic fingerprinting technique single-strand conformation poly-morphism(SSCP).The five processes included denitrifying and phosphate-removal system(diminished N),Chinese traditional medicine wastewater treatment system(P),beer wastewater treatment system(W),fermentative biohydrogen-producing system(H),and sulfate-reduction system(S).The results indicated that the microbial community profiles in the wastewater bioreactors with the uniform status were very similar.The diversity of microbial populations was correlated with the complexity of organic contaminants in wastewater.Chinese traditional medicine wastewater contained more complex organic components;hence,the population diversity was higher than that of simple nutrient bioreactors fed with molasses wastewater.Compared with the strain bands in a simulated community,the relative proportion of some functional microbial populations in bioreactors was not dom-inant.Fermentative biohydrogen producer Ethanoligenens harbinense in the better condition bioreactor had only a 5% band density,and the Desulfovibrio sp.in the sulfate-reducing bioreactor had less than 1.5%band density.The SSCP profiles could identify the difference in microbial community structures in wastewater treatment processes,monitor some of the functional microbes in these processes,and consequently provide useful guidance for improving their efficiency.Yangguo ZHAO Aijie WANG Nanqi REN Yan ZHAO 2008Frontiers of Environmental Science & Engineering2008,2,1:2
6Copolymeriza- tion of ethylene with methyl methacrylate with neutral nickel (II) complexes bearing β-ketoiminato chelate ligands 显示文摘Li Xiaofang Li Yangguo Li Yuesheng 2005Organomet allics2005,24,10:1
7Effect of C/N Ratio on Nitrogen Removal of A/O-MBBR Process for Treating Mariculture Wastewater显示文摘In order to explore the effect of carbon and nitrogen(C/N)ratio on the performance of anoxic/aerobic-moving bed bio-film reactor(A/O-MBBR)process for treating mariculture wastewater,a laboratory-scale A/O-MBBR was conducted.The results showed that the reduction of C/N ratio was conducive to improving the removal efficiency of chemical oxygen demand(COD)and ammonia nitrogen(NH_(4)^(+)-N),while inhibiting that of nitrite nitrogen(NO_(2)^(−)-N)and nitrate nitrogen(NO_(3)^(−)-N).The extracellular polymeric substances(EPS)in anoxic zone were significantly higher in concentration than that in aerobic zone although they both declined with decrease of C/N ratio.The result provides solid support for better controlling the pollution of mariculture wastewater.CHEN Xi XIANG Zhuangzhuang HUANG Xiao RONG Huimin BAI Jie ZHAO Yangguo 2021Journal of Ocean University of China2021,20,4:1
8Salt-tolerant Microbiota Enhancing Contaminants Removal from Mariculture Wastewater Containing Sulfamethoxazole in an A/O-MBBR显示文摘The wide application of antibiotics in aquaculture requires an efficient treatment of the wastewater before discharging it into the environment.During the wastewater treatment,the influence of antibiotics on the performance of bioreactor should be well revealed due to their toxicity to the functional microbial community.In this study,the effect of feeding 10-30 mg L−1 sulfamethoxazole(SMX)in influent on the performance of an anoxic/oxic-moving bed biofilm reactor(A/O-MBBR)treating mariculture wastewater and the responding change of biofilm microbial communities was investigated.The COD average removal rate remained at 94.61%-97.34%with the dosage of SMX.Compared with that,the nitrifying removals of NH4+-N and NO2−-N were violently inhibited by 30 mg L−1 SMX and denitrifying removal of the NO3−-N decreased obviously with 20 mg L−1 or more SMX.The microbial community in the successful startup bioreactor was relatively abundant,while the diversity of microbial community decreased with the increase of feeding SMX.The salt-tolerant and SMX-resistant genera Arcobacter,Thiothrix,Desulfuromusa and Nitrosomonas were gradually enriched and finally played a vital role in converting COD and recycling nitrogen and sulfur.Hence,the present A/O-MBBR reactor with the salt-tolerant functional microbiota achieved efficient removal of pollutants in the presence of low concentration(e.g.,10 mg L−1)SMX.ZHENG Bingbing PANG Wenhui ZHAO Yangguo GUO Liang GAO Mengchun JIN Chunji SHE Zonglian 2020Journal of Ocean University of China2020,19,4:1
9Distribution of phthalate acid esters in lakes of Beijing and its relationship with anthropogenic activities 显示文摘Zheng Xiaoxia Zhang Botao Teng Yangguo 2014Science of the Total Envi- ronment2014,,:1
10Mesoporous Co3O4 sheets/3D graphene networks nanohybrids for high-performance sodium-ion battery anode显示文摘Liu Yangguo Cheng Zhiying Sun Hongyu 2015Journal of Power Sources2015,,273:1
11Automatic Circuit Extractor for HDL Description Using Program Slicing显示文摘Design extraction and reduction have been extensively used in modern VLSI design process. The extracted and reduced design can be efficiently processed by various applications, such as formal verification,simulation, automatic test pattern generation (ATPG), etc. This paper presents a new circuit extraction method using program slicing technique, and develops an elegant theoretical basis based on program slicing for circuit extraction from Verilog description. The technique can obtain a chaining slice for given signals of interest. Compared with related researches, the main advantages of the method include that it is fine grain; it has no hardware description language (HDL) coding style limitation; it is precise and is capable of dealing with various Verilog constructions. The technique has been integrated with a commercial simulation environment and incorporated into a design process. The results of practical designs show the significant benefits of the approach.TunLi YangGuo Si-KunLi 2004Journal of Computer Science & Technology2004,19,5:1
12Response of Heterotrophic Bacteria Abundance and Community Structure to Asian Dust Addition in the Oligotrophic Northwest Pacific Ocean显示文摘The dust storms from the continent usually affect the abundance and diversity of planktons by supplying trace elements. As such, the response of heterotrophic planktonic bacteria to dusts, nutrients(i.e., nitrogen and phosphorus) or ferrous dosages was investigated in the Kuroshio Extension region of the Northwest Pacific Ocean(NWPO) through on-board incubation experiments during an oceanographic survey in spring 2014. The flow cytometry and 16S rRNA high-throughput sequencing methods were applied to explore the abundance and community structure of bacteria, and the percentage of high nucleic acid bacteria(HNA%). The results showed that the heterotrophic bacteria abundance was low(average 2.55×10^5 cells mL^-1) and subjected to both nitrogen(N) and ferrous(Fe) limitation. Sand-dust deposition observably promoted the activity of heterotrophic planktonic bacteria. The maximum abundance of heterotrophic bacteria was 6.98×10^5 cells mL^-1 in the dust-dosage group, which was 44% higher than the control(P < 0.05). The HNA% in the dust-dosage group was 1.37 times higher than the control(P < 0.05). The activation mechanism was mainly related to the dissolution of N and Fe in the dusts. The relative abundance of genus Winogradskyella was significantly increased by dust deposition while the relative abundance of the genera Tenacibaculum and Hyphomonas was decreased. These variations of bacterial community structure were ascribed to the dissolution of nutrients N and P. Comparing the results of different experimental groups, this study concluded that dust storm improved the abundance of heterotrophic bacteria by dissolution of N and Fe.CHEN Xi ZHANG Xiaohao ZHAO Yangguo LIU Guangxing ZHANG Chao GAO Huiwang 2020Journal of Ocean University of China2020,19,3:1
13Insight into the Inhibition of the Poisonous Sulfide Production from Sulfate-Reducing Microbiota in Mariculture Habitat显示文摘The production of toxic sulfides is a common environmental problem in mariculture.Therefore,the effective inhibition of sulfidogens is the key to prevent sulfides production.In this study,the possibility and mechanism of nitrate(NO_(3)^(−))inhibiting the activity of the sulfate-reducing microbiota(SRM)from mariculture sediments was investigated.The results showed that 1,3,and 5 mmol L^(−1)NO_(3)^(−)continuously inhibited sulfide production for 1-3 d.As NO_(3)^(−) dosage increased to 7 mmol L^(−1),the duration of inhibition increased to 6 days.Denitrifying product NO_(2)^(−)heavily inhibited the activity of dissimilar sulfate reductase gene(dsrB)by 3 orders,which was the main reason that the sulfate-reducing activity was inhibited.The SRM structure changed significantly with the dosage of NO_(3)^(−),while the abundance of sulfidogens Desulfovibrio species increased due to their capability of detoxifying nitrite through nitrite reductase.Hence,sulfidogens Desulfovibrio species are more adaptable to a high nitrate/nitrite environment,and the traditional control strategies by dosing nitrate/nitrite should be paid more attention to.The findings will serve as helpful guidelines for sulfate-reducing microbiota in the habitat of mariculture to reduce their generation of poisonous sulfide.ZHAO Xuning ZHANG Zhiming ZHAO Yangguo MUPINDU Progress 2024Journal of Ocean University of China2024,23,2:0
14Impact of Phenanthrene on Denitrification Activity and Transcription of Related Functional Genes in Estuarine and Marine Sediments显示文摘The effects of phenanthrene(Phe)on the denitrification activity and denitrifying genes(narG,nirS and nosZ)were evaluated by dose-response experiments in sediments of Dagu River Estuary(DRE)and Jiaozhou Bay(JZB).The results showed that potential denitrification activity(PDA),N2O,NO3−and NO2−reduction rates of both areas were inhibited with an increase of Phe concentrations.The PDA,N2O,NO3−and NO2−reduction rates of both areas was highest and lowest in the control(DRE:0.453,0.427,7.439 and 3.222mgNkg−1 h−1,JZB:0.592,0.555,8.470 and 3.793mgNkg−1 h−1)and highest Phe amended treatments(DRE:0.069,0.001,4.486,and 1.563 mgNkg−1 h−1;JZB:0.114,0.024,5.527 and 2.200 mgNkg−1 h−1).The inhibition rate of PDA was highest,follow by NO2−reduction and then NO3−reduction.Moreover,with the increasing of Phe concentrations,total bacteria count and the abundance of denitrifying genes were decreased.And N2O accumulation was promoted with the addition of Phe for both areas.Based on the comparison of EC50 values,denitrifiers harboring three genes were more sensitive to Phe than PDA,and denitrifiers harboring nirS gene were more sensitive,followed by nosZ gene,and then narG gene.Furthermore,according to correlation analysis,the relative abundance of denitrifying genes was much more positively correlated with PDA,NO3−and NO2−reduction than total bacteria count.In addition,the denitrification activity and total bacteria count in JZB were more inhibited than that of DRE.This study is useful for understanding the impact of Phe pollution on denitrification in estuary and marine sediments,with profound implications for the management of aquatic ecosystems regarding eutrophication(N-removal)and greenhouse effect.SUN Pengfei BAI Jie LI Kuiran ZHAO Yangguo TIAN Weijun BAI Xiaoyan TIAN Yanzhao 2020Journal of Ocean University of China2020,19,1:0
15Safety and Immunogenicity of SARS-CoV-2 Vaccines in People Living With HIV:A Systematic Review and Meta-analysis of Real-World Studies显示文摘The safety and immunogenicity of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccines in people living with HIV(PLWH)in real-world studies remain controversial.Thus,we conducted a comprehensive systematic review and meta-analysis to address this issue.Data search were conducted from PubMed,Web of Science and EMBASE.Adverse events following vaccination,the risk ratio(RR)of SARS-CoV-2–specific IgG seroconversion and the level of anti–SARS-CoV-2 neutralizing antibodies were compared between the PLWH group and a healthy control group.A total of 10,582 PLWH from 22 studies were included.In our analysis,the incidence of local or systemic adverse events after the first SARS-CoV-2 vaccine dose was not statistically different between PLWH and healthy controls.However,there was a statistical difference after the second dose(RR,0.83;95%CI,0.71–0.98).The seroconversion rate of SARS-CoV-2 IgGantibodies in PLWH was significantly lower than that in the healthy control group(RR,0.94;95%CI,0.89–0.98;I2=80%,P<0.01).The anti–SARS-CoV-2 neutralizing antibody titers in PLWH after full immunization were also significantly lower than those in the healthy control group(RR,0.91;95%CI,0.85–0.98;I2=81%,P<0.01).The safety and tolerance of COVID-19 vaccines in PLWHare acceptable.However,their immunogenicitymay be impaired to a certain extent,characterized by a lower IgGseroconversion rate and neutralizing antibody titers compared with healthy individuals.These findings should provide guidance for optimizing future COVID-19 vaccination strategies among PLWH.Xueying Fan Yangguo Zhao Fan Wu Yue Yuan Bing Lang Di Yin Zhongliang Xu Shiqiang Jiang Huachun Zou Jianhui Yuan Caijun Sun 2023Infectious Microbes & Diseases2023,5,4:0
16Performance Evaluation and Microbial Shift of Sequencing Batch Biofilm Reactor Treating Synthetic Mariculture Wastewater Under Different Dissolved Oxygen at Aerobic Phase显示文摘The impact of dissolved oxygen(DO)at aerobic phase on the nitrogen removal,extracellular polymeric substances(EPS),microbial activity and microbial community of sequencing batch biofilm reactor(SBBR)have been evaluated in treating mariculture wastewater.The oxygen uptake rate and nitrification rate declined with DO concentration from 3–4 to 1–1.5mgL^(-1),whereas the denitrification rate had an increment.The activities of nitrifying enzymes reduced with the decrease of DO concentration at aerobic phase,but those of denitrifying enzymes illustrated opposite results.The nitrification and denitrification rates displayed the similar variation tendency with the relevant enzymatic activities as DO concentration decreased.The protein(PN)and polysaccharide(PS)content in EPS decreased as DO concentration declined,whereas the PN/PS ratio increased.The microbial community showed obvious difference as DO concentration decreased from 3–4 to 1–1.5mgL^(-1).The microbial co-occurrence,keystone taxa and sig-nificant difference illustrated some variations at different DO concentrations.HUO Siyue LIU Wenjie ZHAO Changkun LU Shuailing WANGQianzhi SHE Zonglian ZHAO Yangguo ZHANG Zhiming GUO liang JI Junyuan JIN Chunji GAO Mengchun 2023Journal of Ocean University of China2023,22,6:0
17Enhanced Biodegradation of High-Salinity and Low- Temperature Crude-Oil Wastewater by Immobilized Crude-Oil Biodegrading Microbiota显示文摘High salt and low temperature are the bottlenecks for the remove of oil contaminants by enriched crude-oil degrading microbiota in Liaohe Estuarine Wetland(LEW),China.To improve the performance of crude-oil removal,microbiota was further immobilized by two methods,i.e.,sodium alginate(SA),and polyvinyl alcohol and sodium alginate(PVA+SA).Results showed that the crude oil was effectively removed by the enrichment with an average degrading ratio of 19.42-31.45 mg(L d)^(−1).The optimal inoculum size for the n-alkanes removal was 10%and 99.89%.Some members of genera Acinetobacter,Actinophytocola,Aquabac-terium,Dysgonomonas,Frigidibacter,Sphingobium,Serpens,and Pseudomonas dominated in crude-oil degrading microflora.Though the removal efficiency was lower than free bacteria when the temperature was 15℃,SA and PVA+SA immobilization im-proved the resistance to salinity.The composite crude-oil degrading microbiota in this study demonstrated a perspective potential for crude oil removal from surface water under high salinity and low temperature conditions.HUANG Xiao ZHOU Ting CHEN Xi BAI Jie ZHAO Yangguo 2022Journal of Ocean University of China2022,21,1:0
18面向HDL描述基于程序切片的自动电路抽取技术研究与实现显示文摘现代集成电路设计复杂性在不断增加,而对整个设计进行验证的效率却太低。因此,在形式化验证和模拟验证时,必须采用不同的技术来对设计中的数据通路部分和控制部分分别加以验证。大多数的验证策略都是通过从HDL设计描述中为感兴趣的部分设计提取出有用的验证信息来实现的。TunLi YangGuo Si-KunLi 2004Journal of Computer Science & Technology2004,19,C00:0
19Quantitative (stereological) study of spermatogenesis suppressed Incompletely by testosterone Undecanoate injection in rats显示文摘ZhengweiYang YangGuo LiLin XinghaiWang JiansunTong GuiyuanZhang 2004中国组织化学与细胞化学杂志2004,13,3:0
20Characteristics of Sulfide Removal by Hydrogenovibrio thermophilus Strain TT in Mariculture System显示文摘To biologically inhibit the production of highly toxic sulfide in the aquaculture area,one bacterium,designated as Hydrogenovibrio thermophilus strain TT,was isolated from sediment in Jiaozhou Bay,China.The strain was found to be microaerobic mixtrophic,employing both carbon dioxide and organic carbons,e.g.citrate,lactate,glucose,and peptone as carbon sources.When it oxidized the sulfide and thiosulfate,oxygen was the optimal electron acceptor,followed by nitrite and nitrate,which benefited to removal of sulfide under low-oxygen mariculture environment.In addition,the strain TT exhibited remarkable tolerance of sulfide and thiosulfate in seawater,and it was able to oxidize 18.52 mmol L^-1 S^2-in 12 h or 45 mmol L^-1 S2O3^2-in 24 h at initial pH 7.0-9.0,30-40℃.Therefore,this strain showed a quite promising application for biological remediation of sulfide-contaminated mariculture system.WANG Xiaoqiong ZHAO Yangguo WANG Junpeng ZHANG Mo BAI Jie1 GUO Liang GAO Mengchun 2019Journal of Ocean University of China2019,18,5:0
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