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| 1 | Expression of perforin and granzyme B mRNA in judgement of immunosuppressive effect in rat liver transplantation显示文摘AIM To explore the expression of perform andgranzyme B genes mRNA to judge the effect ofimmunosuppression in acute rejection of livertransplantation.METHODS The expression of perform andgranzyme B genes mRNA was examined byreverse transcriptase-polymerase chain reaction(RT--PCR) in hamster to rat liver grafts under theimmunosuppression of cyclosporine or/andsplenectomy. Histological findings were studiedcomparatively.RESULTS Cyclosporine could obviouslydecrease the cellular infiltration, and completelyrepress the expression of mRNA for perform andgranzyme B, but could not change severehepatocyte necrosis and hemorrhage.SPlenectomy could significantly lightenhepatocyte necrosis, and completely eliminatehemorrhage, but not atfect the cellularinfiltration and the expression of perform andgranzyme B genes mRNA. Cyclosporine orsplenectomy alone could not prolong theSurvival time, however, their combination couldcompletely repress the rejection of liver grafts.The survival time of animals were significantlyprolonged (37.1 days ). The architecture ofhepatic lobules was preserved. There was slightcellular infiltration in the portal tracts and noexpression of perform and granzyme B genesmRNA could be seen in three weeks aftertransplantation.CONCLUSION Perform and granzyme B genesare valuable in judging the effect ofimmunosuppression in liver transplantation. | Zhang SG Wu MC Tan JW Chen H Yang JM Qian QJ | 1999 | World Journal of Gastroenterology1999，5，3： | 15 |
| 2 | Intraspinal transplantation of CD34+ human umbilical cord blood cells after spinal cord hemisection injury improves functional recovery in adult rats显示文摘 | Zhao,ZM Li,HJ Liu,HY Lu,SH Yang,RC Zhang,QJ Han,ZC | 2005 | 中国生物学文摘2005，19，3： | 2 |
| 3 | MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells显示文摘 | Li QJ Zhou L Yang F | | 0，，： | 1 |
| 4 | TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma显示文摘 | Yang P Li QJ Feng Y | 2012 | Cancer Cell2012，22，3： | 1 |
| 5 | In vitro inhibitory effects of scutellarinon six human/rat cytochrome P450 enzymes and P-glycoprotein 显示文摘 | Han YL Li D Yang QJ | 2014 | Molecules2014，19，5： | 1 |
| 6 | Association between the polymorphisms in intercellular adhesion molecule-1 and the risk of coronary atherosclerosis:A case-controlled study显示文摘 | YANG M FU ZK ZHANG QJ | 2014 | PLoS One2014，9，10： | 1 |
| 7 | Inhibitory effects of polysaccharide extract from Spirulina platensis on corneal neovascularization显示文摘 | Yang LL Wang Y Zhou QJ | 2009 | Molecular Vision2009，15，： | 1 |
| 8 | Effect of intravenous immunoglobulin on inhi-biting peripheral blood lymphocyte apoptosis in acute Kawasaki disease显示文摘 | Yi QJ Li CR Yang XQ | 2001 | Acta Paediatr2001，90，6： | 1 |
| 9 | MAP kinase phosphorylationdependent activation of Elk-1 leads to activation of the co-activator p300显示文摘 | Li QJ Yang SH Maeda Y | 2003 | EMBO J2003，22，： | 1 |
| 10 | Hyperbaric oxygen alleviates experimental(spinal cord)injury by downregulating HMGB1/NF-κB expression显示文摘 | Yang J Liu XE Zhou Y Wang GZ Gao CJ Su QJ | 2013 | Spine(Phila Pa 1976)2013，38，26： | 1 |
| 11 | Accounting information and CEO compensation: The role of cash flow from operations in the presence of earning显示文摘 | Nwaeze ET Yang SM and Yin QJ | 2006 | Contemporary Accounting Research2006，，23： | 1 |
| 12 | In vitro inhibitory effects of Scutellarin on six human/rat cytochrome P450 enzymes and P- glycoprotein 显示文摘 | Han YL Li D Yang QJ | 2014 | Molecules2014，19，5： | 1 |
| 13 | Termination of early preg-nancy in the mouse, rat and hamster with DL111-IT andRU486显示文摘 | Yang B Zhou HJ· He QJ | 2000 | Contraception2000，62，4： | 1 |
| 14 | MicroRNA-34a targets Bcl-2 and sen- sitizes human hepatocellular carcinoma cells to sorafenib treatment 显示文摘 | Yang F Li QJ Gong ZB | 2014 | Technol Cancer Res Treat2014，13，1： | 1 |
| 15 | TGF-I3-miR-34a-CCL22 signaling-in- duced Treg cell recruitment promotes venous metastases of HBV- positive hepatocellular carcinoma显示文摘 | Yang P Li QJ Feng Y | 2012 | Cancer Ce112012，22，3： | 1 |
| 16 | MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells 显示文摘 | Li QJ Zhou L Yang F | 2012 | Tumour Biol2012，33，5： | 1 |
| 17 | TGF-beta-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma显示文摘 | Yang P Li QJ Feng Y | | 0，，03： | 1 |
| 18 | A herceptin-based chimericantigen receptor with modified signaling domains leads toenhanced survival of transduced T lymphocytes and antitumoractivity显示文摘 | Zhao Y Wang QJ Yang S | 2009 | Immunol2009，183，9： | 1 |
| 19 | Irradiation enhances human T-cell function by upregulating CD70 expression on antigen-presenting cells in vitro显示文摘 | Huang J Wang QJ Yang S | 2011 | J Immunother2011，34，4： | 1 |
| 20 | In vitro and in vivo induction of bone formation based on ex vivo gene therapy using rat adipose-derived adult stem cells expressing BMP-7显示文摘 | Ma QJ Dang GT | 2005 | Cytotherapy2005，7，3： | 1 |
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