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| 1 | Recent advances in developing small-molecule inhibitors against SARS-CoV-2显示文摘The COVID-19 pandemic caused by the novel SARS-CoV-2 virus has caused havoc across the entire world.Even though several COVID-19 vaccines are currently in distribution worldwide,with others in the pipeline,treatment modalities lag behind.Accordingly,researchers have been working hard to understand the nature of the virus,its mutant strains,and the pathogenesis of the disease in order to uncover possible drug targets and effective therapeutic agents.As the research continues,we now know the genome structure,epidemiological and clinical features,and pathogenic mechanism of SARS-CoV-2.Here,we summarized the potential therapeutic targets involved in the life cycle of the virus.On the basis of these targets,small-molecule prophylactic and therapeutic agents have been or are being developed for prevention and treatment of SARS-CoV-2 infection. | Rong Xiang Zhengsen Yu Yang Wang Lili Wang Shanshan Huo Yanbai Li Ruiying Liang Qinghong Hao Tianlei Ying Yaning Gao Fei Yu Shibo Jiang | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 3 |
| 2 | Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2显示文摘The outbreaks of severe acute respiratory syndrome(SARS)and Coronavirus Disease 2019(COVID-19)caused by SARS-CoV and SARS-CoV-2,respectively,have posed severe threats to global public health and the economy.Treatment and prevention of these viral diseases call for the research and development of human neutralizing monoclonal antibodies(NMAbs).Scientists have screened neutralizing antibodies using the virus receptor-binding domain(RBD)as an antigen,indicating that RBD contains multiple conformational neutralizing epitopes,which are the main structural domains for inducing neutralizing antibodies and T-cell immune responses.This review summarizes the structure and function of RBD and RBD-specific NMAbs against SARS-CoV and SARS-CoV-2 currently under development. | Fei Yu Rong Xiang Xiaoqian Deng Lili Wang Zhengsen Yu Shijun Tian Ruiying Liang Yanbai Li Tianlei Ying Shibo Jiang | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 3 |
| 3 | Particulate flow modelling in a spiral separator by using the Eulerian multi-fluid VOF approach显示文摘The Euler-Euler model is less effective in capturing the free surface of flow film in the spiral separator,and thus a Eulerian multi-fluid volume of fluid(VOF)model was first proposed to describe the particulate flow in spiral separators.In order to improve the applicability of the model in the high solid concentration system,the Bagnold effect was incorporated into the modelling framework.The capability of the proposed model in terms of predicting the flow film shape in a LD9 spiral separator was evaluated via comparison with measured flow film thicknesses reported in literature.Results showed that sharp air–water and air-pulp interfaces can be obtained using the proposed model,and the shapes of the predicted flow films before and after particle addition were reasonably consistent with the observations reported in literature.Furthermore,the experimental and numerical simulation of the separation of quartz and hematite were performed in a laboratory-scale spiral separator.When the Bagnold lift force model was considered,predictions of the grade of iron and solid concentration by mass for different trough lengths were more consistent with experimental data.In the initial development stage,the quartz particles at the bottom of the flow layer were more possible to be lifted due to the Bagnold force.Thus,a better predicted vertical stratification between quartz and hematite particles was obtained,which provided favorable conditions for subsequent radial segregation. | Lingguo Meng Shuling Gao Dezhou Wei Qiang Zhao Baoyu Cui Yanbai Shen Zhenguo Song | 2023 | International Journal of Mining Science and Technology2023，33，2： | 2 |
| 4 | A new UV curable waterborne polyurethane: Effect of C=C content on the film properties 显示文摘 | CHEN Yanbai ZHANG Xingyuan DAI Jiabing | 2006 | Progress in Organic Coatings2006，55，3： | 1 |
| 5 | Microstructure and enhanced H 2 S sensing properties of Pt-loaded WO 3 thin films显示文摘 | Yanbai Shen Baoqing Zhang Xianmin Cao Dezhou Wei Jiawei Ma Lijun Jia Shuling Gao Baoyu Cui Yongcheng Jin | 2014 | Chemical2014，，： | 1 |
| 6 | Influence of effective surface area on gas sensing properties of WO 3 sputtered thin films显示文摘 | Yanbai Shen Toshinari Yamazaki Zhifu Liu Dan Meng Toshio Kikuta Noriyuki Nakatani | 2008 | Thin Solid Films2008，，6： | 1 |
| 7 | Influence of annealing on microstructure and NO 2 -sensing properties of sputtered WO 3 thin films显示文摘 | Zhifu Liu Toshinai Yamazaki Yanbai Shen Toshio Kikuta Noriyuki Nakatani | 2007 | Chemical2007，，1： | 1 |
| 8 | Porous SnO2 Sputtered Films with High H2 Sensitivity at Low Operation Temperature显示文摘 | Yanbai Shen Toshinari Yamazaki Zhifu Liu | 2008 | Thin Solid Films2008，516，15： | 1 |
| 9 | 2- ((1S,3S) - 3 - acetyl - 2, 2 - dimethylcyclobutyl) - N - (2,6 - difluorophenyl ) acetamide显示文摘 | Yin Yanbai Hart Chunrui Song Zhanqian | 2007 | Acta Crystallographica Section E: Structure Reports Online2007，63，04： | 1 |
| 10 | 2 - - N - (m - tolyl) - acetamide显示文摘 | Yin Yanbai Song Zhanqian Wang Zongde | 2008 | Acta Crystallographica Section E: Structure Reports Online2008，64，： | 1 |
| 11 | Novel polyhydroxy cationic collector N-(2,3-propanediol)-Ndodecylamine: Synthesis and flotation performance to hematite and quartz显示文摘To enhance the performance of traditional cationic collector,a novel polyhydroxy amine collector N-(2,3-Propanediol)-N-dodecylamine(PDDA)was designed by introducing one propylene glycol group into dodecylamine(DDA).It was prepared by a nucleophilic substitution reaction,which showed better solubility and hydrophobicity than DDA and was firstly employed as the collector for the separation of hematite and quartz.Flotation tests showed that PDDA had an excellent flotation performance and significantly better selectivity than DDA.In addition,the flotation performance and adsorption mechanism of PDDA on hematite and quartz surfaces were studied using Fourier transform infrared spectroscopy(FTIR),zeta potential and X-ray photoelectron spectroscopy(XPS)tests.These results demonstrated that the interaction between PDDA and the minerals’surfaces was mainly electrostatic adsorption and hydrogen bond,while PDDA tended to adsorb on the surfaces of quartz more than that of hematite.Performance optimization of amine collectors by introducing hydroxyl was also verified,which was of great meaning to the design,development,and application of the polyhydroxy cationic collector.In conclusion,PDDA could be used as a potential collector in the flotation separation of quartz and hematite. | Wenbao Liu Xiangyu Peng Wengang Liu Kelin Tong Yanbai Shen Qiang Zhao Sikai Zhao Wenhan Sun | 2023 | International Journal of Mining Science and Technology2023，33，1： | 1 |
| 12 | High magnetic energy product in isotropic nanocomposite powders with high percent of soft phase towards ultrastrong magnets显示文摘Nanostructure of magnetically hard and soft materials is fascinating for exploring next-generation ul-trastrong permanent magnets with less expensive rare-earth elements.However,the resulting hard/soft nanocomposites often exhibit a low remanence/energy product due to the challenge in obtaining ideal phase components and appropriate soft phase fraction.In this work,a novel microstructure of multiple phases consisting of 1:5 phase and 1:3 phase as main hard phase,and a high ratio of Fe(Co)(27 wt.%-48 wt.%)as soft phase was obtained in Sm-Co(Fe)/Fe nanocomposite magnet.The grain size of both hard and soft phases below 15 nm was observed.The optimal energy product for Sm-Co(Fe)/Fe(Co)nanocom-posite is 2.1 times(an increment of 107%)of the corresponding single-hard-phase powders without soft phase.It reports that the isotropic nanocomposite powders exhibit a record of magnetic energy product larger than 25 MGOe(the highest value is 28.6 MGOe).The high performance and the microstructure achieved in this work for the isotropic powders will shed light on and provide a good premise for syn-thesizing high performance anisotropic bulk nanocomposite magnets. | Longfei Ma Wei Quan Jinkui Fan Yanbai Chen Qiang Zheng Baoru Bian Jian Zhang Juan Du | 2023 | Journal of Materials Science & Technology2023，，13： | 0 |
| 13 | Enhanced detection of ppb-level NO_(2)by uniform Pt-doped ZnSnO_(3)nanocubes显示文摘ZnSnO_(3) nanocubes(ZSNCs)with various Pt concentrations(i.e.,1 at%,2 at%,and 5 at%)were synthesized by a simple one-pot hydrothermal method.The microstructures of pure and Pt-doped ZSNCs were characterized by X-ray diffractometry,scanning electron microscopy,transmission electron microscopy,energy-dispersive X-ray spectroscopy,and X-ray photoelectron spectroscopy.Results showed that the pure ZSNCs have a perovskite structure with a side length of approximately 600 nm;this length was reduced to 400 nm after Pt doping.Following doping,PtO_(x)(PtO and PtO_(2)) nanoparticles with a diameter of approximately 5 nm were uniformly coated on the surface of the ZSNCs.Systematic investigation of the gas-sensing abilities of the nanocubes showed that the Pt-doped ZSNCs have excellent sensing properties toward nitrogen dioxide(NO_(2)) gas in the operating temperature range of 75-175℃.Among the sensors prepared,that based on 1 at%Pt-doped ZSNCs exhibited the best response of 16.0 toward 500 ppb NO_(2) at 125℃;this response is over 11 times higher compared with that of pure ZSNCs.The enhanced NO_(2) sensing mechanism of the Pt-doped ZSNCs may be attributed to the synergistic effects of catalytic activity and chemical sensitization by Pt doping. | Yaoyu Yin Yanbai Shen Sikai Zhao Ang Li Rui Lu Cong Han Baoyu Cui Dezhou Wei | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，6： | 0 |
| 14 | Synthesis and in-situ noble metal modification of WO3·0.33H2O nanorods from a tungsten-containing mineral for enhancing NH3 sensing performance显示文摘Ag-and Pt-doped WO3-0.33 H2O nanorods with high response and selectivity to NH3 were synthesized from a tungsten-containing mine ral of scheelite concentrate by a simple combined process,namely by a high pressure leaching method to obtain tungstate ions-containing leaching solution and followed by a hydrothermal method to prepare corresponding nanorods.The microstructure and NH3 sensing perfo rmance of the final products were investigated systematically.The microstructure characte rization showed that the as-prepared WO3-0.33 H2 O nanorods had a hexagonal crystal structure,and Ag and Pt nanoparticles were uniformly distributed in the WO3-0.33 H2O nano rods.Gas sensing measurements indicated that Ag and Pt nanopa rticles not only could obviously enhance NH3 sensing properties in terms of response,selectivity as well as response/recovery time,but also could reduce the optimal operating temperature at which the highest response was achieved.The highest responses of 22.4 and 47.6 for Agand Pt-doped WO3-0.33 H2O nanorods to 1000 ppm NH3 were obtained at 225 and 175℃,respectively,which were about four and eight folds higher than that of pure one at 250℃.The superior NH3 sensing properties are mainly ascribed to the catalytic activities of noble metals and the different work functions between noble metals and WO3-0.33 H2 O. | Tingting Li Yanbai Shen Sikai Zhao Pengfei Zhou Xiangxi Zhong Shuling Gao Dezhou Wei Fanli Meng | 2020 | Chinese Chemical Letters2020，31，8： | 0 |
| 15 | In-situ growth of V2O5 flower-like structures on ceramic tubes and their trimethylamine sensing properties显示文摘V2O5 flower-like structures assembled by thin nanosheets were in-situ growth on ceramic tubes by hydrothermal process.The structural characterization indicates that V2O5 flower-like structures is orthogonal diamond phase,which entirely covered on the surface of ceramic tubes.TMA sensing measured results revealed that the sensor based on V2O5 flower-like structures exhibited fast reversible and response,good selectivity to TMA and good stability at 200℃.The good sensing performance may be ascribed to flower-like structure s and directly growth sensing film on the ceramic tube without structure damage.Our works give a simple in-situ growth flower-like structures route on sensing device,which exhibits potential application for detecting trace amounts of TMA gas. | Dan Meng Jianpeng Si Mingyue Wang Guosheng Wang Yanbai Shen Xiaoguang San Fanli Meng | 2020 | Chinese Chemical Letters2020，31，8： | 0 |
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