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| 1 | Expression of MRP14 gene is frequently down-regulated in Chinese human esophageal cancer显示文摘Migration inhibitory factor-related protein 14 (MRP 14) is one of calcium-binding proteins,referred as S 100A9. The heterodimeric molecule formed by MRP 14 with its partner MRP8 (S 100A8) is the major fatty acid carrier in neutrophils.The MRP8/14 complex has been also implicated in the intracellular transport of arachidonic acid and its precursors in keratinocytes. We show here the involvement of MRP14 in human esophageal cancer. In an initial study,mRNA differential display - reverse transcription polymerase chain reaction (DD-PCR) was performed with two esophageal carcinomas,one esophageal adenocarcinoma and matched normal adjacent mucosa. DD-PCR with the arbitrary primer OPA3 showed that one cDNA band was highly expressed in normal tissues,but disappeared or substantially decreased in tumor counterparts. It was later identified to be the 3'-end of migration inhibitory factor-related protein 14 (MRP14).Northern blotting,RT-PCR and Western blotting corroborated the down-regulation of MRP14 in 58/64 squamous cell carcinomas and 2/2 adenocarcinomas as compared with adjacent normal epithelia of the esophagus. MRP14 was undetectable in 3/3 esophageal-carcinoma cell lines. Immunochemistry demonstrated that expression of MRP14 was restricted to normal esophageal epithelia. No mutation was found in the genomic DNA of the MRP14 gene by PCR and directed DNA sequencing. Our finding suggested that the reduction of MRP14 expression is a frequent event in Chinese human esophageal cancer. | JieWANG YanCAI HaoXU JunZHAO XinXU YaLingHAN ZhiXiongXU BaoShengCHEN HaiHU MinWU MingRongWANG | 2004 | Cell Research2004，14，1： | 17 |
| 2 | Residential Energy Scheduling for Variable Weather Solar Energy Based on Adaptive Dynamic Programming显示文摘The residential energy scheduling of solar energy is an important research area of smart grid. On the demand side, factors such as household loads, storage batteries, the outside public utility grid and renewable energy resources, are combined together as a nonlinear, time-varying, indefinite and complex system, which is difficult to manage or optimize. Many nations have already applied the residential real-time pricing to balance the burden on their grid. In order to enhance electricity efficiency of the residential micro grid, this paper presents an action dependent heuristic dynamic programming(ADHDP) method to solve the residential energy scheduling problem. The highlights of this paper are listed below. First,the weather-type classification is adopted to establish three types of programming models based on the features of the solar energy. In addition, the priorities of different energy resources are set to reduce the loss of electrical energy transmissions.Second, three ADHDP-based neural networks, which can update themselves during applications, are designed to manage the flows of electricity. Third, simulation results show that the proposed scheduling method has effectively reduced the total electricity cost and improved load balancing process. The comparison with the particle swarm optimization algorithm further proves that the present method has a promising effect on energy management to save cost. | Derong Liu Yancai Xu Qinglai Wei Xinliang Liu | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，1： | 13 |
| 3 | Activity and hydrothermal stability of CeO_2–ZrO_2–WO_3 for the selective catalytic reduction of NO_x with NH_3显示文摘A series of CeO_2–ZrO_2–WO_3(CZW)catalysts prepared by a hydrothermal synthesis method showed excellent catalytic activity for selective catalytic reduction(SCR)of NO with NH_3 over a wide temperature of 150–550°C.The effect of hydrothermal treatment of CZW catalysts on SCR activity was investigated in the presence of 10% H_2O.The fresh catalyst showed above 90% NO_x conversion at 201–459°C,which is applicable to diesel exhaust NO_x purification(200–440°C).The SCR activity results indicated that hydrothermal aging decreased the SCR activity of CZW at low temperatures(below 300°C),while the activity was notably enhanced at high temperature(above 450°C).The aged CZW catalyst(hydrothermal aging at 700°C for 8 hr)showed almost 80% NO_x conversion at 229–550°C,while the V_2O_5–WO_3/TiO_2 catalyst presented above 80% NO_x conversion at 308–370°C.The effect of structural changes,acidity,and redox properties of CZW on the SCR activity was investigated.The results indicated that the excellent hydrothermal stability of CZW was mainly due to the CeO_2–ZrO_2 solid solution,amorphous WO_3 phase and optimal acidity.In addition,the formation of WO_3 clusters increased in size as the hydrothermal aging temperature increased,resulting in the collapse of structure,which could further affect the acidity and redox properties. | Zhongxian Song Ping Ning Qiulin Zhang Hao Li Jinhui Zhang Yancai Wang Xin Liu Zhenzhen Huang | 2016 | Journal of Environmental Sciences2016，28，4： | 7 |
| 4 | Effect of cholecystokinin on experimental neuronal aging显示文摘AIM: To observe the effect of cholecystokinin (CCK) on lipofusin value, neuronal dendrite and spine ultrastructure, and total cellular protein during the process of experimental neuronal aging.METHODS: Experimental neuronal aging study model was established by NBA2cellular serum-free culture method. By using single irtracellular lipofusin value from microspectrophotometry,morphology of neuronal dendrites and spines from the scanner electron microscopy, and total cellular protein as the indexes of experimental neuronal aging, we observed the effect of CCK8 on the process of experimental neuronal aging.RESULTS: Under the condition of serum-free culture,intracellular fluorescence value (%) increased with the extension of culture time (1 d 8.51±3.43; 5 d 10.12±3.03;10 d 20.54±10.3; 15 d 36.88±10.49; bP<0.01). When CCK was added to serum-free culture medium, intracellular lipofusin value (%) decreased remarkably after consecutive CCK reaction for 10 and 15 d (control 36.88±10.49; 5 d 32.03±10.01; 10 d 14.37±5.55; 15 d 17.31±4.80; bP<0.01).As the time of serum-free culturing was prolonged, the number of neuronal dendrite and spine cells decreased.The later increased in number when CCK8 was added. CCK8 could improve the total cellular protein in the process of experimental neuronal aging.CONCLUSION: CCK8 may prolong the process of experimental neuronal aging by maintaining the structure and the number of neuronal dendrite and spine cells and changing the total cellular protein. | Xiao-JiangSun Qin-ChiLu YanCai | 2005 | World Journal of Gastroenterology2005，11，4： | 5 |
| 5 | D-band frontier: A new hydrogen evolution reaction activity descriptor of Pt single-atom catalysts显示文摘Hydrogen evolution reaction(HER) is crucial for achieving sustainable development and carbon neutrality, and thus demands efficient catalysts, which necessitates fundamental theory to relieve trial-and-error experiment. To fast screen HER candidates, most studies focus on d-band center(ε)associated with the Gibbs energy of H* adsorption(ΔG). Unfortunately, εrule is not applicable to Pt single atoms on transition metal disulfides(Pt_(1)/TMDs) because of the additional contributions from p states of S atom. Here, we propose a new HER descriptor — d-band frontier(d) by defining the weight of d-band in the energy range of [-1.0 eV, 1.0 eV] of Pt single atoms. This dis exactly correlated with the ΔGof Pt_(1)/TMDs, and thus perfectly describes the structure–activity relationship, as validated by systematical experimental evidences. Moreover, this ddescriptor can be extended to Pt single atoms anchored on other supports(e.g., CN, C, MoO, and CoO), indicating its promising generality. | Guangming Zhan Yancai Yao Fengjiao Quan Huayu Gu Xiao Liu Lizhi Zhang | 2022 | Journal of Energy Chemistry2022，31，9： | 1 |
| 6 | Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis显示文摘Aim: Correlation of cytochrome P450 (CYPs) with preneoplastic changes in the early stage of hepatocarcinogenesis is still unclear. To detect the expression of carcinogen-metabolizing related microsomal P450 enzymes, namely the CYP1A1,CYP1A2, CYP2B 1/2, CYP2E1, and CYP3A, we performed the medium-term bioassay of Ito's model in Sprague-Dawley rats. Methods: The amount and activity of CYP were assessed by biochemical and immunohistochemical methods in week 8.The correlation between CYP expression and microsomal oxidative stress was investigated by comparing the generation of microsomal lipid peroxidation in the presence or absence of specific CYP inhibitor. Results: In the DEN-2-AAF and 2-AAF alone groups, the expression of CYP1A1 and CYP2E1 were up-regulated and the expression of CYP2B 1/2 and CYP1 A2 were quite the contrary. Strong staining of CYP2E1 and CYP2BI/2 was found around the centrolobular vein and weak staining in the altered hepatic foci revealed by immunohistochemical procedure.There was no significant change in the activity of CYP3A among the 4 groups.Altered hepatic tissue bore more microsomal NADPH (nicotinamide adenine dimucleotide phosphate,reduced form)-dependent lipid peroxidation than normal tissue. And the difference among the 4 groups disappeared when CYP2E1 was inhibited. More microsomal lipid peroxidation was generated when incubated with CYP1A inhibitor α-naphthoflavone. Conclusion: CYP altered their expression levels and these alterations can play important roles in the alteration of cell redox status of preneoplastic tissue in the early stage of hepatocarcinogenesis. | Lin-linLIU Li-kunGONG Xin-mingQI YanCAI HuiWANG Xiong-feiWU YingXIAO JinREN | 2005 | Acta Pharmacologica Sinica2005，26，6： | 1 |
| 7 | Decreased expression of Beclin 1 correlates with a metastatic phenotypic feature and adverse prognosis of gastric carcinomas显示文摘 | Ying‐BoChen Jing‐HuiHou Xing‐YuFeng ShiChen Zhi‐WeiZhou Xiao‐ShiZhang Mu‐YanCai | 2012 | J. Surg. Oncol2012，，： | 1 |
| 8 | Monte Carlo calculation method on low energy electronscattering in polybasic medium显示文摘A novel Monte Carlo method of simulating low energy electron (LEE) scattering in polybasic medium is presented. The Mott cross section is adopted to describe the elastic scattering of LEE, and a mean cross section idea is proposed instead of usual determination of the scattering center. The Joy’’s modified Bethe equation is used to calculate energy loss of LEE. The scattering processes of LEE in bulk PMMA have been simulated. And the electron backscattering coefficients, the electron interaction range and energy dissipation distribution of LEE in bulk PMMA have been calculated and compared with those calculated by the method of determining scattering center. | TAN Zhenyu 1 and HE Yancai 2 1. College of Electric Power, Shandong University of Technology, Jinan 250061, China 2. Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China | 1998 | Chinese Science Bulletin1998，43，2： | 1 |
| 9 | CURRENT STATUS OF ENDOSCOPIC RESECTION IN CHINA显示文摘 | MING‐YANCAI PING‐HONGZHOU LI‐QINGYAO | 2012 | Digestive Endoscopy2012，，： | 1 |
| 10 | Preparation and Certification of a New Salvianolic Acid A Reference Material for Food and Drug Research显示文摘Salvianolic acid A(Sal A),a water-soluble ingredient in Danshen,has various biological activities.Sal A and its impurities have similar physical and chemical properties,as well as strong reducibility;therefore,they are difficult to prepare and purify.In this study,high-purity Sal A was obtained by purification of sephadex chromatography and preparative chromatography.Furthermore,HPLC-DAD tandem ECD and HPLC-DAD tandem MS methods were used for non-volatile organic impurity analysis,ICP-MS method was used for non-volatile inorganic impurities and mass balance method and quantitative nuclear magnetic resonance were employed to certify the product.The structures of Sal A and its relative impurities were validated by nuclear magnetic resonance spectroscopy and mass spectrometry,and their contents were quantified as well.Following the principles of ISO Guides 34:2009 and 35:2005,a Sal A reference material was certified,covering homogeneity studies,stability studies,characterization,and uncertainty estimations. | Dezhi Yang Bin Su Yancai Bi Li Zhang Baoxi Zhang Junke Song Yang Lu Guanhua Du | 2020 | Natural Products and Bioprospecting2020，10，2： | 1 |
| 11 | Cardiac Shock Wave Therapy Reduces Angina and Improves Myocardial Function in Patients With Refractory Coronary Artery Disease显示文摘 | YuWang TaoGuo Hong‐YanCai Tie‐KunMa Si‐MingTao ShuaiSun Ming‐QingChen YunGu Jia‐HuaPang Jian‐MingXiao Xi‐YunYang ChaoYang | 2010 | Clin Cardiol2010，，： | 1 |
| 12 | Atomic level engineering of noble metal nanocrystals for energy conversion catalysis显示文摘It is commonly known that the performance of electrocatalysts is largely influenced by the size,morphology,composition,and crystalline phase of noble metal nanocrystals.However,the limited reserves and high cost of noble metals largely restrict their industrial applications.Along with the development of characterization techniques,theoretical calculations,and advanced material synthesis methods,modulating the electrocatalytic properties of noble metal nanocrystals at the atomic scale(e.g.,monolayer/sub-monolayer,single-atom alloy,ultrafine structure)has been flooding out.Engineering noble metal nanocrystals at the atomic level could not only immensely improve the noble metal atom utilization efficiency and lower the cost,but also boost the catalytic performance.In this review,we summarize the recent advanced progresses of regulating the noble metal nanocrystals at the atomic scale towards energy conversion application.Then,the challenges and perspectives of designing noble metal nanocrystals at the atomic scale in the future are discussed and considered.It is expected that this review will inspire scientists to further study precious metal-based materials for energy-oriented catalysis. | Yancai Yao Shiqi Wang Zhijun Li Yuen Wua | 2021 | Journal of Energy Chemistry2021，30，12： | 1 |
| 13 | Amperometric nitrite sensor based on hemoglobin/colloidal gold nanoparticles immobilized on a glassy carbon electrode by a titania sol-gel film显示文摘 | YANG Weiwei BAI Yu LI Yancai | 2005 | Anal Bioanal Chem2005，382，： | 1 |
| 14 | A highly accessible copper single-atom catalyst for wound antibacterial application显示文摘Bacterial infection arised from multipathogenic bacteria is a tricky issue that attracts worldwide attentions.In this paper,a highly accessible copper single-atom catalyst(Cu SAC)supported by biocompatible N-doped mesoporous carbon nanospheres was synthesized with the emulsion-template method.The tightly anchored copper single-atom of the catalyst could effectively transform O_(2) into O_(2)−•under ambient conditions by the ultra-large pore size(~23.80 nm)and small particle size(~97.71 nm).Due to multiple synergistically oxidative damages to biomolecules,the Cu SAC could be employed to eliminate different bacteria in vitro without the generation of multidrug resistance(MDR).Moreover,the Cu SAC could also promote wound healing in vivo by eradicating the propagation of bacteria at wound.It is envisioned that the Cu SAC with superior antibacterial performance could be applied in the treatment of related bacterial infection in future. | Yue Zhao Yunpeng Yu Feng Gao Zhiyuan Wang Wenxing Chen Cai Chen Jia Yang Yancai Yao Junyi Du Chao Zhao Yuen Wu | 2021 | Nano Research2021，14，12： | 1 |
| 15 | CURRENT STATUS OF ENDOSCOPIC RESECTION IN CHINA显示文摘 | MING‐YANCAI PING‐HONGZHOU LI‐QINGYAO | 2012 | Digestive Endoscopy2012，，： | 1 |
| 16 | The Research on the Assessment of Sustainable Development of County Economy显示文摘 | Yuan Peng Chen Guosheng Ruan Yancai | 2011 | Energy Procedia2011，，： | 1 |
| 17 | Effect of Bonding Temperature on the Microstructures and Strengths of C/C Composite/GH3044 Alloy Joints by Partial Transient Liquid-Phase(PTLP) Bonding with Multiple Interlayers显示文摘With the use of Ti/Ni/Cu/Ni multiple foils as interlayer,carbon/carbon(C/C) composite was bonded to Nibased superalloy GH3044 by partial transient liquid-phase bonding technique.The effect of bonding temperature on the microstructures and strengths of the joints was investigated.The results showed that gradient structural multiple interlayers composed of ‘‘C–Ti reaction layer/Ti–Ni intermetallic compound layer/Ni–Cu sosoloid/residual Cu layer/Ni-GH3044 diffusion layer'' were formed between C/C composite and GH3044.The shear strength of the C/C composite/GH3044 joint reached the highest value of 26.1 MPa when the bonding temperature was 1,030 °C.In addition,the fracture morphology showed that the fracture mode changed with the increase of bonding temperature. | Xin Zhang Xiaohong Shi Jie Wang Hejun Li Kezhi Li Yancai Ren | 2014 | Acta Metallurgica Sinica(English Letters)2014，27，4： | 1 |
| 18 | Analysis of Private Higher Education in China显示文摘 | Yongxiao Cheng Yancai Zheng | 2005 | 美中教育评论2005，2，11： | 0 |
| 19 | Bounds of the Signed Edge Domination Number of Complete Multipartite Graphs显示文摘A function f:E(G)→{−1,1}is called a signed edge dominating function(SEDF for short)of G if f[e]=f(N[e])=Σ_( e′∈N[e])f(e′)≥1,for every edge e∈E(G).w(f)=Σ_(e∈E) f(e)is called the weight of f.The signed edge domination numberγs′(G)of G is the minimum weight among all signed edge dominating functions of G.In this paper,we initiate the study of this parameter for G a complete multipartite graph.We provide the lower and upper bounds ofγs′(G)for G a complete r-partite graph with r even and all parts equal. | Yancai ZHAO | 2023 | Journal of Mathematical Research with Applications2023，43，2： | 0 |
| 20 | A Linear-Time Algorithm for 2-Step Domination in Block Graphs显示文摘The 2-step domination problem is to find a minimum vertex set D of a graph such that every vertex of the graph is either in D or at distance two from some vertex of D.In the present paper,by using a labeling method,we provide an O(m) time algorithm to solve the2-step domination problem on block graphs,a superclass of trees. | Yancai ZHAO Lianying MIAO Zuhua LIAO | 2015 | Journal of Mathematical Research with Applications2015，35，3： | 0 |
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