|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Changes in myocardial protein expression in pacing-induced canine heart failure显示文摘 | Heinke MY Wheeler CH Yan JX | 1999 | Electrophoresis1999，20，： | 1 |
| 2 | Hypomethylation of perforin regulatory elements in CIM + T cells from rat spleens contributes to the development of autoimmune emphysema 显示文摘 | Zhang C Yan MY Lu P | 2014 | Respirology2014，19，： | 1 |
| 3 | Hypomethylation of perforin regulatory elements in CD4 + T ceils from rat spleens contributes to the development of autoimmune emphysema 显示文摘 | Zhang C Yan MY Lu P | 2014 | Respirology2014，19，3： | 1 |
| 4 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
| 5 | Acute cardiovascular effects of insulin-like growth factor I in patients with chronic heart failure显示文摘 | Donath MY Sutsch G Yan XW | 1998 | J Clin Endocrinol Metab1998，83，9： | 1 |
| 6 | Theconcentra: tion distribution of heavy metals under different incin- eration operation conditions显示文摘 | WEI MY SUJ L YAN M H etal | 1998 | The Science of the To- tal Environment1998，212，： | 1 |
| 7 | Physicochemical proper- ties of gelatin gels from walleye pollock(Theragra chalco- gamma) skin cross-linked by gallic acid and rutin显示文摘 | Yan MY Li BF Zhao X | 2011 | Food Hydrocolloids2011，25，5： | 1 |
| 8 | Comparison of acellular dermal graft and palatal autograft in the reconstruction of keratinized gingiva around dental implants:a case report显示文摘 | Tsai AY Wong MY | 2006 | Int J Periodontics Restorative Dent2006，26，3： | 1 |
| 9 | Immediate percutaneous drainage compared with surgical drainage of renal abscess显示文摘 | Hung CH Liou JD Yan MY | 2007 | Int Urol Neph-rol2007，39，1： | 1 |
| 10 | Characterization of acid-soluble collagen fromthe skin of walleye Pollock ( Theragra chalcogramma) 显示文摘 | YAN MY LI B F ZHAO X | 2008 | Food Chemistry2008，107，： | 1 |
| 11 | Clinical Monitoring and Characteristicsof Patients with OSAHS显示文摘 | Cheng W Yang MY Yan K | 2007 | Progress in Modem Biomedicine2007，7，12： | 1 |
| 12 | Development of a chromatographic fingerprint for the chlorofin'm extracts of C, tLnoderma hwidum by HPLC and LC - MS 显示文摘 | Chen Y Yan Y Xie MY | 2008 | J Phann Biomed Analy2008，47，3： | 1 |
| 13 | Hypomethylation of perforin regulatory element in CD4+cells from rat spleens contributes to the development of autoimmune emphysema 显示文摘 | Zhang C Yan MY Lu P | 2014 | Respirology2014，4，1： | 1 |
| 14 | Serum β-2 microglobulin levels predict mortality in dialysis patients: results of the HEMO study显示文摘 | CheungAK Rocco MY Yan 6 | 2006 | J Am Soc Nephrol2006，17，： | 1 |
| 15 | Changes in myocardial protein expression in pacing-induced canine heart failure显示文摘 | Heinke MY Wheeler CH Yan JX | 1999 | Electrophoresis1999，20，10： | 1 |
| 16 | Sann-Joong-Kuey-Jian-Tanginhibits hepatocellular carcinoma Hep-G2 cell proliferation byincreasing TNF-a, Caspase-8, Caspase-3 and Bax but bydecreasing TCTP and Mcl-1 expression in vitro 显示文摘 | ChenYL Yan MY Chien SY | 2013 | Mol Med Rep2013，7，5： | 1 |
| 17 | 显示文摘 | Donath MY Sutsch G Yan XW | 1998 | J Clin Endocrinol Metab1998，83，9： | 1 |
| 18 | SARS-CoV infection in a restaurant from palm civet显示文摘 | Wang M Yan MY Xu HF | 2005 | Emerging Infectious Diseases2005，11，12： | 1 |
| 19 | Comparison of acellular dermal graft and palatal autograft in the reconstruction of keratinized gingiva around dental implants: A case report显示文摘 | Yan J J Tsai AY Wong MY | 2006 | Int J Periodontics Restorative Dent2006，26，3： | 1 |
| 20 | Discrimination of Gano- derma lucidum according to geographical origin with near infrared diffuse reflectance spectroscopy and pattern recog- nition techniques 显示文摘 | Chen Y Xie MY Yan Y | 2008 | Analytica ehimica acta2008，618，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员