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| 1 | Current Controversies and the State of the Art in Endovascular Treatment of Vascular Malformations显示文摘Vascular anomalies constitute some of the most difficult diagnostic and therapeutic enigmas that can be encountered in the practice of medicine. The clinical presentations are extremely protean and can range from an asymptomatic birthmark to fulminant。 | Wayne Yakes Alexis Yakes Fiona Rohlffs Krasnodar Ivancev | 2018 | Journal of Interventional Medicine2018，1，2： | 12 |
| 2 | Diagnosis and management of venous malformations: An overview显示文摘Venous malformations pose some of the most difficult challenges in the practice of medicine today. Clinical manifestations of these lesions are extremely protean. Because of the rarity of these lesions, most clinicians have limited experience in their diagnosis and management, which augments the enormity of the problem and can lead to misdiagnoses, inadequate treatment, high complication rates, and poor patient outcomes. Vascular malformations are best treated in medical centers where patients with these maladies are seen regularly and the team approach is used. The occasional embolizer will never gain enough experience to treat these problematic lesions adequately. More importantly, when complications do occur, the morbidity of that complication is worsened because of this lack of experience and the absence of an experienced team of physicians. All too frequently, the patient ultimately pays for a physician's initial enthusiasm, inexperience, folly, and lack of necessary clinician backup. A cavalier approach to the management of venous malformations will always lead to significant complications and dismal patient outcomes. These patients should be referred to centers that regularly treat vascular malformations, appropriately manage complications in a timely manner, and routinely deal with the dilemmas they present. Only in this fashion can significant experience be gained, improved judgment in managing these lesions develop, and definitive appropriate statements in the treatment of vascular anomalies evolve. | Wayne F. Yakes | 2008 | 中国口腔颌面外科杂志2008，6，1： | 7 |
| 3 | Phytochrome B interacts with SWC6 and ARP6 to regulate H2A.Z deposition and photomorphogensis in Arabidopsis显示文摘Light serves as a crucial environmental cue which modulates plant growth and development, and which is controlled by multiple photoreceptors including the primary red light photoreceptor,phytochrome B(phyB). The signaling mechanism of phyB involves direct interactions with a group of basic helix-loop-helix(bHLH) transcription factors, PHYTOCHROME-INTERACTING FACTORS(PIFs), and the negative regulators of photomorphogenesis, COP1 and SPAs. H2 A.Z is an evolutionarily conserved H2 A variant which plays essential roles in transcriptional regulation. The replacement of H2 A with H2 A.Z is catalyzed by the SWR1 complex. Here, we show that the Pfr form of phyB physically interacts with the SWR1 complex subunits SWC6 and ARP6. phyB and ARP6 coregulate numerous genes in the same direction,some of which are associated with auxin biosynthesis and response including YUC9, which encodes a rate-limiting enzyme in the tryptophandependent auxin biosynthesis pathway. Moreover,phyB and HY5/HYH act to inhibit hypocotyl elongation partially through repression of auxin biosynthesis. Based on our findings and previous studies, we propose that phyB promotes H2 A.Z deposition at YUC9 to inhibit its expression through direct phyB-SWC6/ARP6 interactions,leading to repression of auxin biosynthesis, and thus inhibition of hypocotyl elongation in red light. | Xuxu Wei Wanting Wang Peng Xu Wenxiu Wang Tongtong Guo Shuang Kou Minqing Liu Yake Niu Hong-Quan Yang Zhilei Mao | 2021 | Journal of Integrative Plant Biology2021，63，6： | 6 |
| 4 | Enhancement of strength-ductility balance of heavy Ti and Al alloyed FeCoNiCr high-entropy alloys via boron doping显示文摘As one of the most effective mechanisms,precipitation-hardening is widely used to strengthen high-entropy alloys.Yet,heavy precipitation-hardened high-entropy alloys usually exhibit serious embrittlement.How to effectively achieve ultra-high strength and maintain reliable ductility remains a challenge.Here,we report a study of doping extremely little boron to meet this target.We found that adding of 30 ppm boron into the heavy Ti and Al alloyed FCC FeCoNiCr high-entropy,(FeCoNiCr)_(88) Ti_(6) Al_(6) HEA(at.%)which is strengthened mainly by both coarse BCC-based(Ni,Co)_(2) TiAl Heusler and fine L12-type FCC-based(Ni,Co)_(3) TiAl precipitates and shows ultrahigh strength but poor ductility,could significantly change the original microstructure and consequently improve mechanical performance,owing to the well-known effect of boron on reducing the energy of grain boundaries.The boron addition can(1)eliminate microcavities formed at Heusler precipitate-matrix interfaces;(2)suppress the formation and segregation of coarse BCC Heusler precipitates;(3)promote the formation of L12 nanoparticles.This changes of microstructure substantially improve the tensile ductility more than by~86%and retain comparable or even better ultimate tensile strength.These findings may provide a simple and costless solution to produce heavy precipitation-strengthened HEAs with ultrahigh strength and prevent accidental brittleness. | Yongliang Qi Tinghui Cao Hongxiang Zong Yake Wu Lin He Xiangdong Ding Feng Jiang Shenbao Jin Gang Sha Jun Sun | 2021 | Journal of Materials Science & Technology2021，，16： | 2 |
| 5 | Mid-term outcomes after intramedullary fixation of peritrochanteric femoral fractures using the new proximal femoral nail antirotation (PFNA)显示文摘 | Yake Liu Ran Tao Fan Liu Youhua Wang Zhenyu Zhou Yi Cao Hong Wang | 2010 | Injury2010，，8： | 2 |
| 6 | Synthesis characterization and improved electrochemical performance of Li2FeSiO4/C as cathode for lithium-ion battery by metal doping显示文摘In this paper, Li2FeSi0.98M0.02O4/C(M = Mg, Zn, Co, Mn, Ni) was synthesized as cathode material for lithium ion battery by solid-state method. The results show that the materials doped with Mg and Zn at the Si-sites have good initial discharge capacity. Then Li2FeSi1-xMxO4/C(M = Mg, Zn;x = 0.01, 0.02, 0.03, 0.05) were also synthesized via solid-state method. It is concluded that Li2FeSi0.99Mg0.01O4/C and Li2FeSi0.98Zn0.02O4/C have better initial discharge capacity which is 125 mAh/g and 166.2 mAh/g, respectively. The capacity of Li2Fe0.98Zn0.02SiO4/C is 157.3 m Ah/g after 10 cycles at 0.1 C, and the capacity retention rate is 94.6%. The Li^+ diffusion coefficient of Li2FeSi0.98Zn0.02O4/C is higher than that of pure phase materials by one order of magnitude. The Li2FeSi0.99Mg0.01O4/C and Li2FeSi0.98Zn0.02O4/C were tested by XRD and SEM. XRD patterns indicate that the crystal structure of Li2FeSiO4 is not changed after being doped with metal ion at the Si-site. The SEM image indicates that no obvious agglomeration is detected in these materials. Li2FeSi0.98Zn0.02O4/C processes better electrochemical performance analyzed by EDS、XPS and FT-IR spectra. The data prove that Si4+ is successfully replaced by Zn^2+ in the crystal structure of Li2FeSiO4. | Ling Li Enshan Han Shunpan Qiao Hui Liu Yake Shi Weiliang Yuan | 2019 | Progress in Natural Science:Materials International2019，29，2： | 2 |
| 7 | Can amino-functionalized carbon nanotubes carry functional nerve growth factor?显示文摘Carbon nanotubes can carry protein into cells to induce biological effects. Amino-functionalized carbon nanotubes are soluble and biocompatible, have high reactivity and low toxicity, and can help promote nerve cell growth. In this study, amino-functionalized ethylenediamine-treated multi-walled carbon nanotubes were used to prepare carbon nanotubes-nerve growth factor complexes by non-covalent grafting. The physicochemical properties, cytotoxicity to PC12 and chick embryo dorsal root ganglion, and biological activity of the carbon nanotubes-nerve growth factor complexes were investigated. The results showed that amino functionalization improved carbon nanotubes-nerve growth factor complex dispersibility, reduced their toxicity to PC12 cells, and promoted PC12 cell differentiation and chick embryo dorsal root ganglion. | Wen Chen Qing Xiong Quanxia Ren Yake Guo Gao Li | 2014 | Neural Regeneration Research2014，9，3： | 2 |
| 8 | Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27,cyclin D1,and antitumor action显示文摘 | Yakes FM Chinratanalab W Ritter CA | 2002 | Cancer Res2002，62，14： | 1 |
| 9 | Herceptininduced inhibition of Phosphatidylinositol-3 Kinase and Akt is required for antibody-mediated effects on p27, Cyclin D1, and antitumor action显示文摘 | Yakes FM Chinratanalab W Ritter CA | 2002 | Cancer Res2002，62，14： | 1 |
| 10 | Arteriovenous malformation management 显示文摘 | Yakes WF Rossi P Odink H | 1996 | Cardiovasc Interv Radiol1996，19，2： | 1 |
| 11 | Herceptin-induced inhibition of Phosphatidylinositol-3 Kinase and Akt is required for antibody-mediated effects on p27^Kip1, CyclinDl, and Antitumor action显示文摘 | FMichael Yakes Wichai Chinratalab Christoph ARitter | 2002 | Cancer Res2002，62，15： | 1 |
| 12 | Management of arteriovenous malformations: a multidisciplinary approach显示文摘 | Lee BB Do YS Yakes W | 2004 | J Vasc Surg2004，39，： | 1 |
| 13 | Motochodrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells follwing oxidative stress显示文摘 | Yakes FM Vonhouten B | 1997 | Proc natl Acad Sci USA1997，94，2： | 1 |
| 14 | Lmaging of Symplomalic peripheal vascular malformations显示文摘 | Rak KM Yakes WF Ray RL | 1992 | AJR AMJ Roentgeno11992，159，2： | 1 |
| 15 | Segmental stenosis of the renal artery:pattern recognition of tardus and parvus abnormalities with duplex sonography显示文摘 | Stavros AT Parker SH Yakes WF | | 0，，02： | 1 |
| 16 | Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth显示文摘 | Yakes FM Chen J Tan J | 2011 | Mol Cancer Ther2011，10，12： | 1 |
| 17 | PKB/Akt mediates cellcycle progression by phosphorylation of P27 at threonine 157 and modulation of its cellular localization 显示文摘 | Shin I Yakes FM Rojo F | 2002 | Nature Med2002，8，10： | 1 |
| 18 | Image-directed pereutaneous biopsies with a biopsy gun 显示文摘 | Parker S H Hopper K D Yakes W F | 1989 | Radiology1989，171，3： | 1 |
| 19 | Safe preparation and purification ofsodium tetrakis(3,5-trifluoromethyl)phenyllborate(NaBArF24)-relliable and sensitive analysis of water in solutions of fluorinatedtetraarylborates显示文摘 | Yakelis N A Bergman R G | 2005 | Organometallics2005，24，14： | 1 |
| 20 | Herceptin-induced inhibition of Phosphatidytinositol-3 Kinase and Akt is required for antibody-mediated effects on p27, Cyclin Dl and antitumor action 显示文摘 | Yakes FM Chinratanalab W Ritter CA | 2002 | Cancer Res2002，62，14： | 1 |
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