|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | A simple method for inducing nonalcoholic steatohepatitis with fibrosis显示文摘Background: Nonalcoholic fatty liver disease(NAFLD) is increasingly occurring in sedentary people, and may progress to NASH and hepatocellular carcinoma. It is essential to design affordable animal models for the study of various diseases, including fatty liver, which was the aim of the study. In this study, a high-fat diet was devised that triggers NASH’s animal model quickly and easily. High-fat diet(HFD) was used both with intra-mouth oral gavage and in combination with animal pellets.Methods: Twenty-four male C57 BL/6 J mice were divided into HFD and ND groups, which received a high-fat diet and a normal diet, respectively. At the end of the experiment(fourth week of treatment), body and liver weights, biochemical parameters, PPAR-α gene expression and histopathologic characteristics of the liver were evaluated.Results: During 4 weeks, body weight of mice did not show a significant increase in the HFD group compared to the ND group, while weight gain of the liver was significant. Histological assessment of the HFD group’s liver confirmed NASH symptoms. In the HFD group, HDL-c, SOD, catalase, FRAP, adiponectin, and PPAR-α decreased significantly, and lipid profiles, hepatic enzymes, MDA, leptin, and TNF-α showed a significant increase compared to the ND group.Conclusion: Our high-fat diet has successfully induced all aspects of NASH with fibrosis in 4 weeks, and with low cost. | Leyla Yahaghi Azadeh Ebrahim-Habibi Nasim Hayati-Roodbari Shiva Irani Parichehreh Yaghmaei | 2019 | Animal Models and Experimental Medicine2019，2，4： | 2 |
| 2 | Heavy metal tolerance of fungi 显示文摘 | Anahid S Yaghmaei S Ghobadinejad Z | 2011 | Sci Iran2011，18，3： | 1 |
| 3 | Comparison of bioleaching ability of two native mesophilic and thermophilic bacteria on copper recovery from ehalcopyrite concentrate in an airlift bioreaetor显示文摘 | MOUSAVI S YAGHMAEI S VOSSOUGHI M JAFARI A HOSEINI S | 2005 | Hydrometallurgy2005，80，1： | 1 |
| 4 | Investigation on the effect oflemon peel essential oil in blood level lipids number of differentialleukocytes of Wistar rats 显示文摘 | P Yaghmaei K Parivar M Haft Savar | 2009 | Journal of the Neurological Sciences2009，283，12： | 1 |
| 5 | Polymorphisms of glutathione S-transferase M1, T1, and P1 in patients with HBV-related liver cirrhosis, chronic hepatitis, and normal carriers显示文摘 | Ghobadloo S M Yaghmaei B Allameh A | 2006 | Clin Biochem2006，39，： | 1 |
| 6 | Comparison of bioleaching ability of two native mesophilic and thermophilic bacteria on copper recovery from chalcopyrite concentrate in an airlift bioreactor显示文摘 | MOUSAVI S M YAGHMAEI S VOSSOUGHI M JAFARI A HOSEINI S A | | 0，，： | 1 |
| 7 | Heavy metal tolerance of fungi显示文摘 | S Anahid S Yaghmaei Z Ghobadinejad | 2011 | Scientia Iranica2011，18，3： | 1 |
| 8 | Silymarin effect on amyloid-beta plaque accumulation and gene expression of APP in an Alzheimer's disease rat model 显示文摘 | Yaghmaei P Azarfar K Dezfulian M | 2014 | Daru2014，22，1： | 1 |
| 9 | Computer simulation of fluid motion in a porous bed using a volume of fluid method:Application in heap leaching显示文摘 | MOUSAVI S M JAFARI A YAGHMAEI S VOSSOUGHI M SARKOMAA P | 2006 | Minerals Engineering2006，19，10： | 1 |
| 10 | Bayesian Estimation of Generalized Half Logistic Distribution under Progres-sive Type-II Censored显示文摘 | Reza Azimi Farhad Yaghmaei Manoochehr Babanezhad | 2012 | Applied Mathematical Sciences2012，，106： | 1 |
| 11 | Computer simulation of fluid motion in a porous bed using a volume of fluid method: Application in heap leaching显示文摘 | S.M. Mousavi A. Jafari S. Yaghmaei M. Vossoughi P. Sarkomaa | 2006 | Minerals Engineering2006，，10： | 1 |
| 12 | 氢的燃烧反应对乙烷在固定床催化膜反应器中脱氢反应的影响(英文)显示文摘A two-dimensional non-isothermal mathematical model has been developed for the ethane dehydrogenation reaction in a fixed-bed catalytic membrane reactor. Since ethane dehydrogenation is an equilibrium reaction,removal of produced hydrogen by the membrane shifts the thermodynamic equilibrium to ethylene production.For further displacement of the dehydrogenation reaction, oxidative dehydrogenation method has been used.Since ethane dehydrogenation is an endothermic reaction, the energy produced by the oxidative dehydrogenation method is consumed by the dehydrogenation reaction. The results show that the oxidative dehydrogenation method generated a substantial improvement in the reactor performance in terms of high conversions and signi ficant energy saving. It was also established that the sweep gas velocity in the shell side of the reactor is one of the most important factors in the effectiveness of the reactor. | Masoud Hasany Mohammad Malakootikhah Vahid Rahmanian Soheila Yaghmaei | 2015 | Chinese Journal of Chemical Engineering2015，23，8： | 1 |
| 13 | Heavy metal tolerance of fungi 显示文摘 | Anahid S Yaghmaei S Ghobadinejad Z | 2011 | Scientia lranica2011，18，3： | 1 |
| 14 | Comparison of bioleaching ability of two native mesophilic and thermophilic bacteria on copper recovery from chalcopyrite concentrate in an airlift bioreactor 显示文摘 | MOUSAVI S M YAGHMAEI S VOSSOUGHI M JAFARI A HOSEINI S A | 2005 | Hydrometallurgy2005，80，1： | 1 |
| 15 | Compari son of Bioleaehing Ability of Two Native Mesophilic and Thermophilic Bacteria on Copper Recovery From Chal- copyrite Concentrate in An Airlift Bioreactor显示文摘 | Mousavi S M Yaghmaei S Vossoughi M | 2005 | Hydro- metallurgy2005，80，12： | 1 |
| 16 | A molecular description of ligand binding to the two overlapping bind- ing pockets of the nuclear vitamin D receptor (VDR) : structure-function implications显示文摘 | Mizwicki MT Menegaz D Yaghmaei S | 2010 | J Steroid Biochem Mol Biol2010，121，12： | 1 |
| 17 | Comparison of bioleaching ability of two native mesophilic and thermophilic bacte- ria on copper recovery from chalcopyrite concen- trate in an airlift bioreactor显示文摘 | MOUSAVI S M YAGHMAEI S VOSSOU- GHI M | 2005 | Hydrometallur- gy2005，80，12： | 1 |
| 18 | Use of amni-on as a graft material in Vestibuloplasty : a preliminary report显示文摘 | Samandari MH Yaghmaei M Ejlali M | 2004 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2004，97，5： | 1 |
| 19 | Bacterial leaching of low- grade ZnS concentrate using indigenous mesophilic and thermophilic strains显示文摘 | Mousavi SM Yaghmaei S Vossoughi M | 2007 | Hydrometallurgy2007，85，8： | 1 |
| 20 | Computer simulation of fluid motion in a porous bed using a volume of fluid method: Application in heap leaching 显示文摘 | Mousavi S M Jafari A Yaghmaei S | 2006 | Minerals Engineering2006，19，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员