|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy显示文摘BACKGROUND:The major issue with intraoperative cholangiography (IOC) is whether its diagnostic accuracy for common bile duct (CBD) stones matches that of other diagnostic procedures,and thus,whether it will become a routine diagnostic procedure.The current study aimed to address the main determinants of CBD stone diagnosis in IOC among an Iranian population.METHODS:In a retrospective review database-based study conducted in Taleghani Hospital in Tehran between 2006 and 2008,baseline data and perioperative information of 2060 patients (male to female ratio 542:1518,mean age 53.7 years) who were candidates for cholecystectomy and underwent concomitant IOC for confirming CBD stones were reviewed.The predictive power of this procedure for diagnosis of abnormal biliary ducts with the focus on biliary stones was determined.RESULTS:Overall mortality and morbidity following cholecystectomy in the study population were 0.6% and 2.6%,respectively.Both early mortality and morbidity due to cholecystectomy were higher in male than female.The prevalence of CBD stones in IOC was 3.4% (5.2% in male and 2.8% in female,P=0.008).Among those without gallstones,8.7% had CBD stones and only 3.1% had concomitant gallstones and CBD stones.The main predictors of stone appearance as an abnormal feature of IOC during cholecystectomy were:advanced age (OR=1.022,P=0.001),male gender (OR=1.498,P=0.050),history of abdominal surgery (OR=1.543,P=0.040) and preoperative endoscopic retrograde cholangiopancreatography (OR=5.400,P<0.001).CONCLUSIONS:IOC is a safe and accurate method for the assessment of bile duct anatomy and stones.Therefore,the routine use of IOC within cholecystectomy seems reasonable and is recommended. | Shahram Yousefpour Azary Heshmat Kalbasi Ali Setayesh Mirhadi Mousavi Asad Hashemi Mahsa Khodadoostan Mohammad Reza Zali Amir Houshang Mohammad Alizadeh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 11 |
| 2 | Effect of ultrasonic irradiation on rheological properties of asphaltenic crude oils显示文摘In this work, the rheological changes of several crude oil samples exposed to ultrasonic waves for different time intervals in addition to the effect of temperature on viscosity behavior of heavy crude oils were investigated using a series of steady shear flow and oscillatory tests. The colloidal structural evolutions of flocs in oil samples were illustrated by analysis of the size distribution of flocculated asphaltene particles (confocal microscopy tests). The rheological investigations indicate that the ultrasonic irradiation dissolved heavy components in crude oil. After ultrasonic treatment, the Kouh-e-Mond crude oil was found to be pseudoplastic. In addition, confocal microscopy confirms that there was an optimum duration for ultrasonic irradiation, at which the viscosity and flocculation rate of asphaltenic crude oils reduced to the minimum values. The optimum was found to be approximately 40 min for the Kouh-e-Mond crude oil. Experimental results illustrate that the ultrasonic irradiation could disaggregate heavy colloid components in crude oil, and breakdown of asphaltene molecules would only occur in a specific time interval of irradiation. Also according to the temperature sweep test, the oil temperature rise caused by ultrasonic irradiation was not the main reason for rheological changes of the crude oil and this alteration may be due to physical and chemical phenomena induced by sonication in crude oil. | MOUSAVI Seyed Mohammadreza RAMAZANI Ahmad NAJAFI Iman DAVACHI Seyed Mohammad | 2012 | Petroleum Science2012，9，1： | 10 |
| 3 | Ultrasound-assistant preparation of Cu-SAPO-34 nanocatalyst for selective catalytic reduction of NO by NH_3显示文摘The influence of the various preparation methods of Cu-SAPO-34 nanocatalysts on the selective catalytic reduction of NO with NH3 under excess oxygen was studied. Cu-SAPO-34 nanocatalysts were prepared by using four techniques: conventional impregnation(IM),ultrasound-enhanced impregnation(UIM), conventional deposition precipitation(DP) using Na OH and homogeneous deposition precipitation(HDP) using urea. These catalysts were characterized in detail by various techniques such as N2-sorption, XRD, TEM, H2-TPR,NH3-TPD and XPS to understand the catalyst structure, the nature and the dispersed state of the copper species, and the acid sites for NH3 adsorption. All of the nanocatalysts showed high activities for NO removal. However, the activities were different and followed the sequence of Cu-SAPO-34(UIM) > Cu-SAPO-34(HDP) > Cu-SAPO-34(IM) > Cu-SAPO-34(DP).Based on the obtained results, it was concluded that the NO conversion on Cu-SAPO-34 nanocatalysts was mainly related to the high reducibility of the isolated Cu2+ions and Cu O species, the number of the acid sites and the dispersion of Cu O species on SAPO-34. | Parvaneh Nakhostin Panahi Ali Niaei Darush Salari Seyed Mahdi Mousavi Gérard Delahay | 2015 | Journal of Environmental Sciences2015，27，9： | 7 |
| 4 | 镍−铝−青铜合金表面类金刚石涂层的腐蚀性能和摩擦学行为显示文摘研究阴极电弧沉积制备的类金刚石(DLC)涂层对镍−铝−青铜(NAB)合金力学性能、摩擦学行为和腐蚀性能的影响。纳米硬度测试显示,与NAB合金相比,DLC涂层具有更大的硬度。销盘摩擦测试显示,摩擦因数由NAB合金的0.2降低为DLC涂层的0.13。动电位极化和电化学阻抗谱结果表明,在3.5%(质量分数)的NaCl溶液中,腐蚀电流密度由NAB合金的2.5μA/cm2降低到DLC涂层的0.14μA/cm2。此外,基体−电解质界面的电荷转移电阻由NAB合金的3.3 kΩ·cm2提高到DLC涂层的120.8 kΩ·cm2,表明DLC涂层能提高合金的耐腐蚀性能。 | Seyed Elias MOUSAVI Nastaran NAGHSHEHKESH Mohabbat AMIRNEJAD Hossein SHAMMAKHI Ali SONBOLI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，2： | 6 |
| 5 | Wettability alteration and oil recovery by spontaneous imbibition of smart water and surfactants into carbonates显示文摘Naturally fractured carbonate reservoirs have very low oil recovery efficiency owing to their wettability and tightness of matrix.However,smart water can enhance oil recovery by changing the wettability of the carbonate rock surface from oilwet to water-wet,and the addition of surfactants can also change surface wettability.In the present study,the effects of a solution of modified seawater with some surfactants,namely C12 TAB,SDS,and TritonX-100(TX-100),on the wettability of carbonate rock were investigated through contact angle measurements.Oil recovery was studied using spontaneous imbibition tests at 25,70,and 90°C,followed by thermal gravity analysis to measure the amount of adsorbed material on the carbonate surface.The results indicated that Ca2+,Mg2+,and SO42-.ions may alter the carbonate rock wettability from oil-wet to water-wet,with further water wettability obtained at higher concentrations of the ions in modified seawater.Removal of NaCl from the imbibing fluid resulted in a reduced contact angle and significantly enhanced oil recovery.Low oil recoveries were obtained with modified seawater at 25 and 70°C,but once the temperature was increased to 90°C,the oil recovery in the spontaneous imbibition experiment increased dramatically.Application of smart water with C12 TAB surfactant at 0.1 wt%changed the contact angle from 161°to 52°and enhanced oil recovery to 72%,while the presence of the anionic surfactant SDS at 0.1 wt%in the smart water increased oil recovery to 64.5%.The TGA analysis results indicated that the adsorbed materials on the carbonate surface were minimal for the solution containing seawater with C12 TAB at 0.1 wt%(SW+CTAB(0.1 wt%)).Based on the experimental results,a mechanism was proposed for wettability alteration of carbonate rocks using smart water with SDS and C12 TAB surfactants. | Saeb Ahmadi Mostafa Hosseini Ebrahim Tangestani Seyyed Ebrahim Mousavi Mohammad Niazi | 2020 | Petroleum Science2020，17，3： | 6 |
| 6 | Contribution of tuned liquid column gas dampers to the performance of offshore wind turbines under wind, wave, and seismic excitations显示文摘The main intention of the present study is to reduce wind, wave, and seismic induced vibrations of jackettype offshore wind turbines(JOWTs) through a newly developed vibration absorber, called tuned liquid column gas damper(TLCGD). Using a Simulink-based model, an analytical model is developed to simulate global behavior of JOWTs under different dynamic excitations. The study is followed by a parametric study to explore efficiency of the TLCGD in terms of nacelle acceleration reduction under wind, wave, and earthquake loads. Study results indicate that optimum frequency of the TLCGD is rather insensitive to excitation type. In addition, while the gain in vibration control from TLCGDs with higher mass ratios is generally more pronounced, heavy TLCGDs are more sensitive to their tuned frequency such that ill-regulated TLCGD with high mass ratio can lead to destructive results. It is revealed that a well regulated TLCGD has noticeable contribution to the dynamic response of the JOWT under any excitation. | Khosrow Bargi Reza Dezvareh Seyed Amin Mousavi | 2016 | Earthquake Engineering and Engineering Vibration2016，15，3： | 6 |
| 7 | Novel ternary g-C_3N_4/Fe_3O_4/MnWO_4 nanocomposites: Synthesis,characterization, and visible-light photocatalytic performance for environmental purposes显示文摘The g-C_3 N_4/Fe_3 O_4/MnWO_4 nanocomposites were prepared by a refluxing-calcination procedure. Visiblelight-induced photocatalytic experiments showed that the g-C_3 N_4/Fe_3 O_4/MnWO_4(10%) nanocomposite has excellent ability to degrade a range of contaminants including rhodamine B, methylene blue, methyl orange, and fuchsine, which is about 7, 10, 25, and 31 times of the g-C_3 N_4 photocatalyst, respectively.Reactive species trapping experiments revealed that superoxide anion radicals play major role in the photodegradation reaction of rhodamine B(RhB). After the treatment process, the utilized photocatalyst was magnetically recovered and reused with negligible loss in the photocatalytic activity, which is vital in the photocatalytic processes. Finally, a mechanism was proposed for the enhanced interfacial carrier separation and transfer and the improved photocatalytic performance. | Mitra Mousavi Aziz Habibi-Yangjeh Davod Seifzadeh | 2018 | Journal of Materials Science & Technology2018，34，9： | 6 |
| 8 | Cadmium nanoclusters in a protein matrix: Synthesis, characterization, and application in targeted drug delivery and cellular imaging显示文摘Biotemplated 金属 nanoclusters 在 biosensing, bioimaging,催化作用,和 nanomedicine 由于他们潜在的应用的宽范围积累了许多注意。这里,我们报导马厩的合成, biocompatible,水溶性、高度荧光灯的牛的浆液白朊模板镉 nanoclusters (Cd 通过一个灵巧的一个壶绿色方法的 NC ) 。我们 covalently 结合了玻尿的酸(哈) 到 Cd 形成的 NC 一 pH 应答,有为 doxorubicin (纪录影片) 的持续版本侧面的 tumortargeting theranostic nanocarrier,模型 anticancer 药。nanocarrier 显示出大约 75.6% 的纪录影片封装效率。纪录影片版本侧面表明 74% 纪录影片在 pH 被释放 5.3,当不到 26% 纪录影片在 pH 被释放时 7.4 在一样的 24-h 时期以内。nanocarrier 有选择地认出了表示 CD44 的 MCF-7 乳癌房间,房间表面受体为哈,而没有如此的识别被观察与哈受体否定的 HEK293 房间。nanocarrier 的 Biocompatibility 与 HEK293 和 MCF-7 房间通过 cytotoxicity 试金被评估。展出的 nanocarrier 对没有 cytotoxicity 很低,而装载纪录影片的 nanocarrier 显示出可观的细胞的举起并且提高了 MCF-7 乳癌杀死房间的能力。我们也证实了使用的可行性高度荧光灯为 MCF-7 和 HeLa 房间的 bioimaging 的 nanoconjugate。优异的指向的药交货功效,细胞的成像能力,和低 cytotoxicity 用有希望的生物医学的应用作为令人激动的新 nanoplatform 放这 nanoconjugate。 | Morteza Sarparast Abolhassan Noori Hoda Ilkhani S. Zahra Bathaie Maher F. EI-Kady Lisa J. Wang Huong Pham Kristofer L. Marsh Richard B. Kaner Mir F. Mousavi | 2016 | Nano Research2016，9，11： | 5 |
| 9 | Accumulation of heavy metal in Platanus orientalis, Robinia pseudoacacia and Fraxinus rotundifolia显示文摘Plants are capable of reducing environmental pollutions through uptaking contaminants in their tissues. In the study site, twenty one-year-old leaves and shoots as well as twenty soil samples were sampled and analyzed by Inductively Coupled Plasma (ICP). We investigated the uptaking ability of lead (Pb) and cadmium (Cd) by the leaves and shoots of Platanus orientalis, Robinia pseudoacacia and Fraxinus rotundifolia in Karaj city, the western Tehran, Iran. We also evaluated the total metal accumulation capacity by using metal accumulation index (MAI). Results indicated that there was no significant difference in uptaking contents of Cd and Pb in the leaves among the trees. However accumulation of Cd in shoots of F. rotundifolia and R. pseudoacacia was significantly higher than that of P. orientalis. The accumulation of Pb in shoots of R. pseudoacacia was significantly higher than the other species. The amount of Pb in the soil of the study area was significantly higher than Cd. Concentrations of Cd and Pb in leaves of the three species are in the ranges of 2.4 2.7 mg Kg-1 and 7.1 14.4 mg Kg-1 , respectively. R. pseudoacacia had the highest MAI value for leaves (2.21) and F. rotundifolia had the highest MAI value for shoots (2.4). | Sajjad Hosseinzadeh Monfared Mohammad Matinizadeh Anoushirvan Shirvany Ghavamedin Zahedi Amiri Reza Mousavi Fard Fariba Rostami | 2013 | Journal of Forestry Research2013，24，2： | 5 |
| 10 | Optimum geometry of tuned liquid column-gas damper for control of offshore jacket platform vibrations under seismic excitation显示文摘In this study, the effectiveness of a tuned liquid column-gas damper, TLCGD, on the suppression of seismic-induced vibrations of steel jacket platforms is evaluated. TLCGD is an interesting choice in the case of jacket platforms because it is possible to use the structural elements as the horizontal column of the TLCGD. The objective here is to find the optimum geometric parameters, namely orientation and configuration of vertical columns, length ratio, and area ratio of the TLCGD, considering nonlinear damping of the TLCGD and water-structure interaction between the jacket platform and sea water. The effects of different characteristics of ground motion such as PGA and frequency content on the optimum geometry are also investigated and it is observed that these features have some influence on the optimum area ratio. Finally it is observed that pulse arrangement of ground acceleration is one of the most important parameters affecting the efficiency of a TLCGD. In other words, it is found that the TLCGD's capability to reduce the RMS responses depends only on the frequency content of the ground acceleration, but its capability to reduce the maximum responses depends on both the frequency content and the pulse arrangement of the ground acceleration. | Seyed Amin Mousavi Seyed Mehdi Zahrai Khosrow Bargi | 2012 | Earthquake Engineering and Engineering Vibration2012，11，4： | 4 |
| 11 | Characteristics of a multi-component MgO-based bioceramic coating synthesized in-situ by plasma electrolytic oxidation显示文摘Plasma electrolytic oxidation(PEO)has held great potential for the advancement of biodegradable implants,as it helps in developing porous bioceramic coatings on the surface of magnesium alloys.In this research work,MgO-based bioceramic coatings containing the Si,P,Ca,Na,and F elements have been successfully fabricated on an AZ31 magnesium alloy plate utilizing the PEO method.The characteristic current-voltage behavior of the samples during the process was surveyed in an electrolyte containing Ca(H_(2)PO_(4))_(2),Na_(2)SiO_(3)·9H_(2)O,Na_(3)PO_(4)·12H_(2)O,NaF,and KOH with a pH of 12.5 and electrical conductivity of 20 mS/cm^(-1).The results revealed that applying a voltage of 350-400 V(that is 50-100 V higher than the breakdown limit)could greatly facilitate the synthesis of a PEO ceramic coating with fewer defects and more uniform morphology.The resulting coating was a compositionally graded bioceramic layer with a thickness in the range of 3.5±0.4 to 6.0±0.7µm,comprising the above-mentioned elements as promising bioactive agents.The synthesized ceramic features were investigated in terms of the elemental distribution of components through the thickness,which indicated a gradual rise in the Si and P contents and,conversely,a decline in the F content towards the outer surface.The growth mechanism of the PEO coating has been discussed accordingly. | Nasrinsadat Azarian Seyed Mohammad Mousavi Khoei | 2021 | Journal of Magnesium and Alloys2021，9，5： | 4 |
| 12 | Reconstruction based approach to sensor fault diagnosis using auto-associative neural networks显示文摘Fault diagnostics is an important research area including different techniques.Principal component analysis(PCA)is a linear technique which has been widely used.For nonlinear processes,however,the nonlinear principal component analysis(NLPCA)should be applied.In this work,NLPCA based on auto-associative neural network(AANN)was applied to model a chemical process using historical data.First,the residuals generated by the AANN were used for fault detection and then a reconstruction based approach called enhanced AANN(E-AANN)was presented to isolate and reconstruct the faulty sensor simultaneously.The proposed method was implemented on a continuous stirred tank heater(CSTH)and used to detect and isolate two types of faults(drift and offset)for a sensor.The results show that the proposed method can detect,isolate and reconstruct the occurred fault properly. | Mousavi Hamidreza Shahbazian Mehdi Jazayeri-Rad Hooshang Nekounam Aliakbar | 2014 | Journal of Central South University2014，21，6： | 4 |
| 13 | Azithromycin in one week quadruple therapy for H pylori eradication in Iran显示文摘瞄准:调查根除率,耐心的依从和 1-wk 的 toler 能力基于 Azithromycin 的四倍的治疗对 2-wk 常规治疗。方法: 129 个 H pylori积极的病人的一个总数被使随机化到任何一个 omeprazole 20 mg ,铋潜水艇柠檬酸盐 240 mg , azithromycin 250 mg ,和灭滴灵 500 mg ,为 1-wk ( B-OAzM )两次每日的所有或 omeprazole 20 mg ,铋潜水艇柠檬酸盐 240 mg , amoxicillin 1 g ,并且灭滴灵 500 mg 为 2-wk (B操作维护管理)两次每日的所有。H pylori 感染被组织学和快速的 urease 在入口定义,感染的痊愈被否定的脲呼吸测试决定。结果:B-OAzM 和 B 操作维护管理生产的 H pylori 根除率基于一个意愿分别地是 74.1% 和 70.4% 对待分析,并且 78.1% 对 75.7% 分别地基于每协议分析。,差的依从的发生更低不显著地那么,比为 B 操作维护管理(3.5% 对 4.3%) 在病人使随机化到 B-OAzM,但是难耐在二个组(35% 对 33.3%) 是类似的。结论:基于的四倍的政体完成的 1-wk azithromycin 比得上标准 2-wk 的 H pylori 根除率四倍的治疗,并且与可比较的耐心的依从和复杂并发症被联系。 | Shahrokh Mousavi Jafar Toussy Siamak Yaghmaie Mehrdad Zahmatkesh | 2006 | World Journal of Gastroenterology2006，12，28： | 3 |
| 14 | Optimum placement and characteristics of velocity-dependent dampers under seismic excitation显示文摘In this study,through novel drift-based equations of motion in the frequency domain,optimum placement and characteristics of linear velocity-dependent dampers are investigated.In this study,the sum of the square of the absolute values of transfer matrix elements for interstory drifts is considered as the optimization index.Optimum placement and characteristics of dampers are simultaneously obtained by minimizing the optimization index through an incremental procedure.In each step of the procedure,a predefined value is considered as the damper characteristic.The optimum story for this increment is selected such that it leads to a minimum value for the optimization index.The procedure is repeated for the next increments until the optimization index meets its target value,which is obtained according to the desired damping ratio for the overall structure.In other words,the desired overall damping ratio is the input to the proposed procedure,and the optimal placement and characteristics of the dampers are its output.It is observed that the optimal placement of a velocitydependent damper depends on the damping coefficient of the added damper,frequency of the excitation,and distribution of the mass,stiffness,and inherent damping of the main structure. | Seyed Amin Mousavi Amir K.Ghorbani-Tanha | 2012 | Earthquake Engineering and Engineering Vibration2012，11，3： | 3 |
| 15 | 搅拌摩擦焊接工艺参数和搅拌头外形尺寸对3003-H18铝合金和低碳钢焊接性能的影响(英文)显示文摘采用搅拌摩擦焊工艺对3mm厚3003-H18铝合金和低碳钢板进行焊接,获得了无缺陷的对接焊接头。对一个适用于同种金属搅拌摩擦焊的热量输入模型进行简化,以用来研究异种金属搅拌摩擦焊接速度、旋转速度和搅拌头轴肩直径对焊接组织和性能的影响。对焊接组织、金属间化合物和接头强度的比较表明,实验结果与通过简化模型计算得到的热量输入因子(HIF)吻合较好。当HIF值介于0.2~0.4之间时,焊接接头强度受Al/Fe界面的控制;当HIF值介于0.4~0.8之间时,其强度受铝热力学影响区强度的控制;当HIF〉0.8时,其强度受金属间化合物或缺陷的控制。 | M.DEHGHANI S.A.A.AKBARI MOUSAVI A.AMADEH | 2013 | Transactions of Nonferrous Metals Society of China2013，23，7： | 3 |
| 16 | Effects of rhubarb(Rheum ribes L.)syrup on dysenteric diarrhea in children:a randomized,double-blind,placebo-controlled trial显示文摘BACKGROUND:Rheum ribes L.is a plant native to China,Iran,Turkey,India,and a few other countries.Antidiarrheal activity is considered to be one of its important properties according to various systems of traditional medicine.An increasing rate of bacterial resistance to antibiotics has led to treatment failure in some cases of shigellosis in children,and underlines a need for safe,efficient and valid options.OBJECTIVE:The purpose of this study is to evaluate the efficacy of R.ribes syrup as a complementary medicine for treatment of shigellosis in children.DESIGN,SETTING,PARTICIPANTS AND INTERVENTIONS:This randomized,doubleblind,placebocontrolled trial started with a group of 150 children aged between 12–72 months with suspected Shigella dysentery.R.ribes syrup or placebo syrup was administered to the intervention and control groups,respectively for 5 days.In addition,the standard antibiotic treatment(ceftriaxone for the first 3 days and cefixime syrup for 2 further days)was administered to both groups.MAIN OUTCOME MEASURES:Body temperature,abdominal pain,need for antipyretics,defecation frequency,stool volume and consistency and microscopic stool examination were recorded as outcome measures.Any observed adverse effects were also recorded.RESULTS:Mean duration of fever and diarrhea in the R.ribes group was significantly lower than that in the placebo group(P=0.016 and 0.001,respectively).In addition,patients in the R.ribes group showed shorter duration of need for antipyretics and shorter duration of abdominal pain(P=0.012 and 0.001,respectively).However,there were no significant differences between the two groups regarding the microscopic stool analyses.Furthermore,no adverse effect was reported.CONCLUSION:R.ribes syrup can be recommended as a complementary treatment for children with Shigella dysentery. | Ali Khiveh Mohammad Hashem Hashempur Mehrdad Shakiba Mohammad Hassan Lotfi Afsaneh Shakeri Seid Kazem Kazemeini Zohre Mousavi Marzie Jabbari Mohammad Kamalinejad Majid Emtiazy | 2017 | Journal of Integrative Medicine2017，15，5： | 3 |
| 17 | Microstructural analyses of aluminum–magnesium–silicon alloys welded by pulsed Nd: YAG laser welding显示文摘Revealing grains and very fine dendrites in a solidified weld metal of aluminum–magnesium–silicon alloys is difficult and thus,there is no evidence to validate the micro-and meso-scale physical models for hot cracks. In this research, the effect of preheating on the microstructure and hot crack creation in the pulsed laser welding of AA 6061 was investigated by an optical microscope and field emission electron microscopy. Etching was carried out in the gas phase using fresh Keller’s reagent for 600 s. The results showed that the grain size of the weld metal was proportional to the grain size of the base metal and was independent of the preheating temperature. Hot cracks passed the grain boundaries of the weld and the base metal. Lower solidification rates in the preheated samples led to coarser arm spacing;therefore, a lower cooling rate. Despite the results predicted by the micro and meso-scale models, lower cooling rates resulted in increased hot cracks. The cracks could grow in the weld metal after solidification;therefore, hot cracks were larger than predicted by the hot crack prediction models. | Hossain Ebrahimzadeh Hassan Farhangi Seyed Ali Asghar Akbari Mousavi Arman Ghahramani | 2020 | International Journal of Minerals,Metallurgy and Materials2020，27，5： | 3 |
| 18 | Metformin alleviates cholestasis-associated nephropathy through regulating oxidative stress and mitochondrial function显示文摘Background and aim:Cholestasis-associated renal injury or cholemic nephropathy(CN)is a serious clinical problem.Previous studies mentioned that oxidative stress and mitochondrial impairment play a role in CN.There is no specific pharmacological intervention for CN.Metformin is an anti-diabetic drug administered for decades.On the other hand,novel pharmacological properties have emerged for this drug.The effect of metformin on oxidative stress parameters has been well-recognized in different experimental models.It has also been found that metformin positively affected mitochondrial function.The current study aimed to evaluate the effects of metformin in an animal model of CN.Methods:Rats underwent bile duct ligation(BDL)and were treated with metformin(250 and 500 mg/kg)for 14 consecutive days.Two weeks after the BDL operations,urine,serum,and kidney samples were collected and analyzed.Results:Markers of oxidative stress,including reactive oxygen species(ROS)formation,lipid peroxida-tion,protein carbonylation,depleted antioxidant capacity,and decreased glutathione(GSH)levels were detected in BDL animals.Moreover,mitochondrial indices,including adenosine triphosphate(ATP)level,dehydrogenase activity,mitochondrial membrane potential,and mitochondrial permeability,were impaired in the kidney of cholestatic rats.Renal histopathological alterations in cholestatic animals included tubular degeneration and interstitial inflammation,cast formation,and fibrosis.It was found that metformin significantly alleviated oxidative stress and improved mitochondrial indices in the kidney of cholestatic rats.Tissue histopathological alterations were also mitigated in metformin-treated groups.Conclusions:Metformin could be a candidate for managing CN.The nephroprotective role of metformin is primarily associated with its effects on oxidative stress parameters and mitochondrial function. | Mohammad Mehdi Ommati Hamidreza Mohammadi Khadijeh Mousavi Negar Azarpira Omid Farshad Reyhaneh Dehghani Asma Najibi Sedigheh Kamran Hossein Niknahad Reza Heidari | 2021 | Liver Research2021，5，3： | 3 |
| 19 | Imperialistic Competitive Algorithm:A metaheuristic algorithm for locating the critical slip surface in 2-Dimensional soil slopes显示文摘In this study, Imperialistic Competitive Algorithm(ICA) is utilized for locating the critical failure surface and computing the factor of safety(FOS) in a slope stability analysis based on the limit equilibrium approach. The factor of safety relating to each trial slip surface is calculated using a simplified algorithm of the Morgenstern-Price method, which satisfies both the force and the moment equilibriums. General slip surface is considered non-circular in this study that is constituted by linking random straight lines.To explore the performance of the proposed algorithm, four benchmark test problems are analyzed. The results demonstrate that the present techniques can provide reliable, accurate and efficient solutions for locating the critical failure surface and relating FOS. Moreover, in contrast with previous studies the present algorithm could reach the lower value of FOS and reached more exact solutions. | Ali Reza Kashani Amir Hossein Gandomi Mehdi Mousavi | 2016 | Geoscience Frontiers2016，7，1： | 3 |
| 20 | Endoscopic retrograde cholangiopancreatography outcome from a single referral center in Iran显示文摘BACKGROUND: Endoscopic retrograde cholangiopancreato- graphy (ERCP) is the first choice for diagnostic evaluation of the pancreatic and biliary tree and can be accompanied by a high diagnostic sensitivity and a poor therapeutic outcome. In the current study, we described our experiences in the indications, findings, and technical success of ERCP in a sample of the Iranian population admitted to a referral center in Iran. METHODS: In a retrospective review database-based study, 780 patients (393 males and 387 females; mean age 57.5 years) who had undergone diagnostic and therapeutic ERCP with the primary diagnosis of hepatobiliary disorder between 2006 and 2008 at Taleghani Hospital in Tehran were reviewed. The key data were demographic characteristics, clinical information, laboratory parameters, as well as post-ERCP complications. RESULTS: A history of cholecystectomy was found in about one-third (36.3%) of participants and 80 (10.3%) out of 780 patients had a previous history of biliary stone. A minority (1.4%) of the patients suffered from hepatobiliary carcinomas, and 11 patients had cirrhosis. The most common clinical manifestations in the patients undergoing diagnostic ERCP were icterus (47.3%), weight loss (31.2%), and dark urine (26.9%). Selective biliary cannulation was technically successful in 87.0% of the patients; however, cannulation failed in 13.0%. The most frequent final diagnosis of ERCP was common bile duct stone that was detected in 40.1% of the patients. The ERCP results in 11.0% of the patients were normal. Regarding appropriate treatment, successful stenting was performed in 43 patients (15.2%). Among post-ERCP complications, pancreatitis was the most adverse event withan incidence rate of 3.3%. Other complications including local bleeding, cholangitis and gastrointestinal perforation, rarely occurred. Post-ERCP pancreatitis was reported in 1.8% of men and 3.6% of women (P=0.120). Pancreatitis was more common in women below 70 years than in those who were older than 70 years (3.6% versus 0.5%; OR: 8.216, P=0.015). This might be due to the more functionally active pancreas in younger women than in the older ones. However, other complications were similar in the two age groups. CONCLUSIONS: Based on our experience, ERCP indications, final diagnosis and related complications are comparatively consistent with those reported in other countries. The most common post-ERCP complication is pancreatitis that is more often observed in younger patients. | Amir H Mohammad Alizadeh Esmaeil S Afzali Mirhadi Mousavi Yaghoub Moaddab Mohammad R Zali | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，4： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员