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| 1 | 雷暴冲击风模拟及其荷载的风洞试验研究显示文摘为了研究在突变气流作用下结构的空气动力特性,介绍了利用主动控制风洞模拟突变气流的试验研究。首先通过该风洞模拟出了雷暴冲击风阵风剖面;然后,采用'阶跃流法'模拟了风速突变的时程;最后将高层结构模型置于该突变气流中,观测在特殊气流中结构表面风压以及结构空气动力学参数的变化特征。试验结果表明,利用主动控制风洞模拟出的雷暴冲击风阵风剖面同理论的相似性达到90%以上,突变气流会使高层结构整体产生较大的非定常升力,并且在结构表面产生较大的非定常风压。 | 赵杨 曹曙阳 Yukio Tamura 段忠东 S. Ozono | 2009 | 振动与冲击2009，28，4： | 24 |
| 2 | Novel 3-dimensional virtual hepatectomy simulation combined with real-time deformation显示文摘AIM:To develop a novel 3-dimensional(3D) virtual hepatectomy simulation software,Liversim,to visualize the real-time deformation of the liver.METHODS:We developed a novel real-time virtual hepatectomy simulation software program called Liversim. The software provides 4 basic functions:viewing 3D models from arbitrary directions,changing the colors and opacities of the models,deforming the models based on user interaction,and incising the liver parenchyma and intrahepatic vessels based on user operations. From April 2010 through 2013,99 patients underwent virtual hepatectomies that used the conventional software program SYNAPSE VINCENT preoperatively. Between April 2012 and October 2013,11 patients received virtual hepatectomies using the novel software program Liversim; these hepatectomies were performed both preoperatively and at the same that the actual hepatectomy was performed in an operating room. The perioperative outcomes were analyzed between the patients for whom SYNAPSE VINCENT was used and those for whom Liversim wasused. Furthermore,medical students and surgical residents were asked to complete questionnaires regarding the new software.RESULTS:There were no obvious discrepancies(i.e.,the emergence of branches in the portal vein or hepatic vein or the depth and direction of the resection line) between our simulation and the actual surgery during the resection process. The median operating time was 304 min(range,110 to 846) in the VINCENT group and 397 min(range,232 to 497) in the Liversim group(P = 0.30). The median amount of intraoperative bleeding was 510 m L(range,18 to 5120) in the VINCENT group and 470 m L(range,130 to 1600) in the Liversim group(P = 0.44). The median postoperative stay was 12 d(range,6 to 100) in the VINCENT group and 13 d(range,9 to 21) in the Liversim group(P = 0.36). There were no significant differences in the preoperative outcomes between the two groups. Liversim was not found to be clinically inferior to SYNAPSE VINCENT. Both students and surgical residents reported that the Liversim image was almost the same as the actual hepatectomy.CONCLUSION:Virtual hepatectomy with real-time deformation of the liver using Liversim is useful for the safe performance of hepatectomies and for surgical education. | Yukio Oshiro Hiroaki Yano Jun Mitani Sangtae Kim Jaejeong Kim Kiyoshi Fukunaga Nobuhiro Ohkohchi | 2015 | World Journal of Gastroenterology2015，21，34： | 23 |
| 3 | Pancreatic neuroendocrine tumor and solid-pseudopapillary neoplasm: Key immunohistochemical profiles for differential diagnosis显示文摘AIM To reveal better diagnostic markers for differentiating neuroendocrine tumor(NET) from solid-pseudopapillary neoplasm(SPN), focusing primarily on immunohistochemical analysis.METHODS We reviewed 30 pancreatic surgical specimens of NET(24 cases) and SPN(6 cases). We carried out comprehensive immunohistochemical profiling using 9 markers: Synaptophysin, chromogranin A, pancytokeratin, E-cadherin, progesterone receptor,vimentin, α-1-antitrypsin, CD10, and β-catenin.RESULTS E-cadherin staining in NETs, and nuclear labeling of β-catenin in SPNs were the most sensitive and specific markers. Dot-like staining of chromogranin A might indicate the possibility of SPNs rather than NETs. The other six markers were not useful because their expression overlapped widely between NETs and SPNs. Moreover, two cases that had been initially diagnosed as NETs on the basis of their morphological features, demonstrated SPN-like immunohistochemical profiles. Careful diagnosis is crucial as we actually found two confusing cases showing disagreement between the tumor morphology and immunohistochemical profiles.CONCLUSION E-cadherin, chromogranin A, and β-catenin were the most useful markers which should be employed for differentiating between NET and SPN. | Yusuke Ohara Tatsuya Oda Shinji Hashimoto Yoshimasa Akashi Ryoichi Miyamoto Tsuyoshi Enomoto Kaishi Satomi Yukio Morishita Nobuhiro Ohkohchi | 2016 | World Journal of Gastroenterology2016，22，38： | 19 |
| 4 | 柱面壳体表面风压分布特性风洞试验研究显示文摘基于刚性模型的风洞试验,在不同风攻角及场地条件下,对考虑不同长跨比的柱面壳体表面风压分布进行了同步测量.根据测量结果对壳体表面风压场特性进行了分析,包括风压系数、整体风力系数、脉动风压自功率谱及互功率谱、风压场本征正交分解特性、雷诺数对壳体表面风压分布的影响等.结果表明,此类曲面模型表面风压分布受雷诺数影响明显,且模型曲面特性使得风场本征正交分解的前几阶特征模态对整个风压分布的贡献增大. | 李元齐 Tamura Yukio 沈祖炎 | 2006 | 同济大学学报(自然科学版)2006，34，11： | 18 |
| 5 | Selection of appropriate endoscopic therapies for duodenal tumors: An open-label study, single-center experience显示文摘AIM:To determine an appropriate compartmentalization of endoscopic submucosal dissection(ESD)or endoscopic mucosal resection(EMR)for duodenal tumors.METHODS:Forty-six duodenal lesions(excluding papillary lesions)from 44 patients with duodenal tumors treated endoscopically between 2005 and 2013 were divided into the ESD and EMR groups for retrospective comparison and analysis.RESULTS:The mean age was 65±9 years(35-79years).There were 24 lesions from men and 22 from women.The lesions consisted of 6 early cancers,31adenomas and 9 neuroendocrine tumors.Lesion location was the duodenal bulb in 15 cases and the descending part of the duodenum in 31 cases.The most common macroscopic morphology was elevated type in 21 cases(45.6%).Mean tumor diameter was 11.9±9.7 mm(3-60 mm).Treatment procedure was ESD(15 cases)vs EMR(31 cases).The examined parameters in the ESD vs EMR groups were as follows:mean tumor diameter,12.9±14.3 mm(3-60 mm)vs 11.4 ±6.7 mm(4-25 mm);en bloc resection rate,86.7%vs 83.9%;complete resection rate,86.7%vs 74.2%;procedure time,86.5±63.1 min(15-217 min)vs 13.2±17.0 min(2-89 min)(P<0.0001);intraprocedural perforation,3 cases vs none(P=0.0300);delayed perforation,none in either group;postprocedural bleeding,1 case vs none;mean postoperative length of hospitalization,8.2±2.9 d(5-16 d)vs 6.1±2.0 d(2-12 d)(P=0.0067);recurrence,none vs 1 case(occurring at 7 mo postoperatively).CONCLUSION:ESD was associated with a longer procedure time and a higher incidence of intraprocedural perforation;EMR was associated with a lower rate of complete resection. | Satohiro Matsumoto Yukio Yoshida | 2014 | World Journal of Gastroenterology2014，20，26： | 17 |
| 6 | Branched-chain amino acid treatment before transcatheter arterial chemoembolization for hepatocellular carcinoma显示文摘AIM:To examine the significance of branched-chain amino acid (BCAA) treatment before transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).METHODS:This study included 99 patients who underwent TACE therapy for HCC at our hospital and were followed up without treatment for at least 6 mo between January 2004 and January 2010.They were divided into 2 groups:those receiving BCAA granules (n=40) or regular diet (n=59,control).Data obtained were retrospectively analyzed (prior to TACE,and 1 wk,1,3,and 6 mo after TACE) in terms of nutritional condition and clinical laboratory parameters (serum albumin level and Child-Pugh score),both of which are determinants of hepatic functional reserve.RESULTS:The BCAA group comprised 27 males and 13 females with a mean age of 69.9 ± 8.8 years.The patients of the BCAA group were classified as follows:Child-Pugh A/B/C in 22/15/3 patients,and Stage Ⅱ/Ⅲ /ⅣA HCC in 12/23/5 patients,respectively.The controlgroup comprised 32 males and 27 females with a mean age of 73.2 ± 10.1 years.In the control group,9 patients had chronic hepatitis,Child-Pugh A/B/C in 39/10/1 patients,and StageⅠ/Ⅱ/Ⅲ/ⅣA HCC in 1/11/35/12 patients,respectively.Overall,both serum albumin level and Child-Pugh score improved significantly in the BCAA group as compared with the control 3 and 6 mo after TACE (P < 0.05).Further analysis was performed by the following categorization:(1) child-Pugh classification;(2) liver cirrhosis subgroup with a serum albumin level > 3.5 g/dL;and (3) epirubicin dose.A similar trend indicating a significant improvement of all variables in the BCAA group was noted (P < 0.05).CONCLUSION:Treatment with BCAA granules in patients who have undergone TACE for HCC is considered useful to maintain their hepatic functional reserve. | Hiroki Nishikawa Yukio Osaki Tadashi Inuzuka Haruhiko Takeda Jun Nakajima Fumihiro Matsuda Shinichiro Henmi Azusa Sakamoto Tetsuro Ishikawa Sumio Saito Ryuichi Kita Toru Kimura | 2012 | World Journal of Gastroenterology2012，18，12： | 16 |
| 7 | Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies显示文摘Dear Editor,Mutations in the β-globin gene,the essential component of adult hemoglobin(HbA;a2p2),results in either a production of aberrant sickle hemoglobin(HbS)leading to sickle cell disease(SCD)or an insufficient β-globin synthesis leading to β-thalassemia.These two major forms of β-hemoglobinopathies cause impaired erythropoiesis and life-threatening anemia.Clinical evidence has suggested that reaaivation of fetal γ-globin(HBG)gene expression which is normally silenced after birth by certain genetic mutations can ameliorate the clinical course of β-hemoglobinopathies. | Liren Wang Linxi Li Yanlin Ma Handan Hu Qi Li Yang Yang Wenbang Liu Shuming Yin Wei Li Bin Fu Ryo Kurita Yukio Nakamura Mingyao Liu Yongrong Lai Dali Li | 2020 | Cell Research2020，30，3： | 14 |
| 8 | Vitamin D and calcium are required at the time of denosumab administration during osteoporosis treatment显示文摘To evaluate the differences in outcomes of treatment with denosumab alone or denosumab combined with vitamin D and calcium supplementation in patients with primary osteoporosis. Patients were split into a denosumab monotherapy group(18 cases) or a denosumab plus vitamin D supplementation group(combination group; 23 cases). We measured serum bone alkaline phosphatase(BAP), tartrate-resistant acid phosphatase(TRACP)-5 b and urinary N-terminal telopeptide of type-I collagen(NTX) at baseline, 1 week, as well as at 1 month and 2, 4, 8 and 12 months. We also measured bone mineral density(BMD) of L1–4 lumbar vertebrae(L)-BMD and bilateral hips(H)-BMD at baseline and at 4, 8 and 12 months. There was no significant difference in patient background. TRACP-5 b and urinary NTX were significantly suppressed in both groups from 1 week to 12 months(except at 12 months for NTX). In the combination group, TRACP-5 b was significantly decreased compared with the denosumab monotherapy group at 2 and 4 months(P < 0.05).BAP was significantly suppressed in both groups at 2–12 months. L-BMD significantly increased at 8 and12 months(8.9%) in the combination group and at 4, 8 and 12 months(6.0%) in the denosumab monotherapy group, compared with those before treatment. H-BMD was significantly increased in the combination group(3.6%) compared with the denosumab group(1.2%) at 12 months(P < 0.05). Compared with denosumab monotherapy, combination therapy of denosumab with vitamin D and calcium stopped the decrease in calcium caused by denosumab, inhibited bone metabolism to a greater extent, and increased BMD(especially at the hips). | Yukio Nakamura Takako Suzuki Mikio Kamimura Kohei Murakami Shota Ikegami Shigeharu Uchiyama Hiroyuki Kato | 2017 | Bone Research2017，5，4： | 11 |
| 9 | 生活方式与血压关系的研究显示文摘目的 探讨生活方式与血压之间的关系。方法 采用流行病学现况研究的方法 ,对重庆市某厂 5个车间所有 45~ 5 5岁的男性进行调查。结果 该人群平均年龄 5 1岁 ,平均收缩压 (SBP)与舒张压 (DBP)分别为 12 0 2 1mmHg( 15 99kPa) ,79 89mmHg( 10 6 3kPa)。高血压现患率为 2 0 3%,高胆固醇血症现患率为 16 7%,超重率为2 3 4%。单因素分析显示 ,体重指数 (BMI)与SBP和DBP均呈正相关 (r=0 33 ,r=0 41,P <0 0 1)。超重的人 (BMI≥ 2 5kg/m2 )其SBP、DBP、血清总胆固醇 (TC)、TC/HDL值均较体重指数正常者高。Logistic回归分析显示 ,超重是高血压患病的危险因素 ,OR值为 4 92 ( 2 43~ 9 95 )。 2 4h尿钠排出量与血压呈弱的相关 (r =0 2 3 ,r =0 2 2 ,P <0 0 5 ) ,钠 /钾均值为 6 77,钠 /钾高于建议值范围 (比值 <3)的比例占 98 5 5 %。文化程度高 (受教育年数≥ 10年 )有低的高血压现患 ( 5 6 5 %) ,其血压水平、尿钠排出量、钠 /钾均较中、低文化程度的低。结论 超重、膳食高盐为重庆地区抽样人群高血压患病的危险因素 ,教育在中国人群血压控制中扮演着重要的角色。 | 牟李红 卢仙娥 刘隆健 赵禾 彭佑群 Yukio Yamori 胡志琼 许红 唐晓君 | 2003 | 中国公共卫生2003，19，5： | 11 |
| 10 | Risk factors for postoperative bleeding after gastric endoscopic submucosal dissection in patients under antithrombotics显示文摘AIM: To evaluate the risk factors for postoperative bleeding after gastric endoscopic submucosal dissection(ESD) based on the latest guidelines.METHODS: A total of 262 gastric neoplasms were treated by ESD at our center during a 2-year period from October 2012. We analyzed the data of these cases retrospectively to identify the risk factors for postESD bleeding.RESULTS: Of the 48(18.3%) cases on antithrombotic treatment, 10 were still receiving antiplatelet drugs perioperatively, 13 were on heparin replacement after oral anticoagulant withdrawal, and the antithrombotic therapy was discontinued perioperatively in 25 cases. Postoperative bleeding occurred in 23 cases(8.8%). The postoperative bleeding rate in the heparin replacement group was 61.5%, significantly higher than that in the non-antithrombotic therapy group(6.1%). Univariate analysis identified history of antithrombotic drug use, heparin replacement, hemodialysis, cardiovascular disease, diabetes mellitus, elevated prothrombin timeinternational normalized ratio, and low hemoglobin level on admission as risk factors for post ESD bleeding. Multivariate analysis identified only heparin replacement(OR = 13.7, 95%CI: 1.2-151.3, P = 0.0329) as a significant risk factor for post-ESD bleeding.CONCLUSION: Continued administration of antiplatelet agents, based on the guidelines, was not a risk factor for postoperative bleeding after gastric ESD; however, heparin replacement, which is recommended after withdrawal of oral anticoagulants, was identified as a significant risk factor. | Yuji Shindo Satohiro Matsumoto Hiroyuki Miyatani Yukio Yoshida Hirosato Mashima | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，7： | 10 |
| 11 | Acute effects of physical exercise in type 2 diabetes: A review显示文摘The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort. | Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José Fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes | 2014 | World Journal of Diabetes2014，5，5： | 8 |
| 12 | 多国荷载规范中阵风荷载因子的比较研究显示文摘将我国的《建筑结构荷载规范》(GB5009-2001)与美国(ASCE7-98)、日本(RLB-AIJ2004)、加拿大(NBC1990)和澳大利亚(AS1170.2)几国规范进行了比较研究.首先总结了各国规范所采用的Davenport提出的经典抗风设计方法——阵风荷载因子法(GLF),然后对包括平均风速剖面、湍流强度、脉动风速谱类型进行了比较.美日加澳都将GLF取为一个恒量,相当于'位移风振系数',中国规范中的风振系数却是随高度变化的量,相当于'惯性力风振系数'. | 赵杨 段忠东 Yukio Tamura 武岳 | 2010 | 哈尔滨工程大学学报2010，31，11： | 8 |
| 13 | 日本的泡沫经济与土地利用变化(英文)显示文摘自1981年起日本经历了长达10年的泡沫经济时期,经济过热的现象于1991年12月突然终止。这一时期对日本的土地和经济造成了许多长远的影响,这是一个无论从经济学视角还是土地利用视角都非常严肃却在学术上又非常有趣的现象。来自地方的土地利用变化趋势调查报告(1980—2005)揭示了政府政策以及地方权力机构的意图是如何影响土地利用的,不同类型的土地利用是如何响应泡沫经济的,而泡沫经济又对土地产生了怎样影响。本研究揭示了在泡沫经济下人类活动影响土地的一些明显的规律。这些规律非常值得其他国家、特别是亚洲的发展中国家借鉴,以减轻或回避经济过热对土地和环境带来的灾难性后果。 | Yukio Himiyama | 2006 | 地球科学进展2006，21，2： | 8 |
| 14 | Long-term prognostic impact of circulating tumour cells in gastric cancer patients显示文摘AIM To analyse the long-term prognostic impact of circulating tumour cells(CTCs) in gastric cancer patients who underwent surgery. METHODS A 7.5-m L peripheral vein blood sample was obtained from each patient with treatment-negative gastric adenocarcinoma before surgery. OBP-401, a telomerasespecific, replication-selective, oncolytic adenoviral agent carrying the green fluorescent protein gene, was used to label CTCs. Correlations between the number of CTCs and clinical end points were evaluated. RESULTS The median follow-up period of the surviving patients with gastric cancer was 60 mo. The CTC number tended to increase concomitantly with disease progression. The overall survival of patients with more than five CTCs in 7.5-m L of peripheral blood was lower than that of patients with five or less CTCs, although the difference was not significant(P = 0.183). A significant difference in relapse-free survival was found between patients with more than five and those with five or less CTCs(P = 0.034).CONCLUSION A lower number of CTCs was correlated with higher relapse-free survival rates in patients. Detection of CTCs using OBP-401 may be useful for predicting prognosis in gastric cancer. | Hiroaki Ito Jun Sato Yukio Tsujino Noriko Yamaguchi Satoshi Kimura Keigo Gohda Katsuhiro Murakami Manabu Onimaru Tohru Ohmori Fumihiro Ishikawa Haruhiro Inoue | 2016 | World Journal of Gastroenterology2016，22，46： | 8 |
| 15 | 利用HHT方法对非平稳风力的时频分析显示文摘非平稳信号的分析方法是信号分析领域中的一个重要问题。以风洞试验获得的非平稳风压信号和升力系数信号为研究对象,采用HHT方法对信号进行时频分析。HHT(Hilbert-Huang transform)方法可以获得有意义的瞬时频率,从而给出频率随时间变化的精确表达;信号最终被表示为时频平面上的能量分布,成为Hilbert谱;该方法适用于分析生活中普遍存在的大量频率随时间变化的非线性、非平稳信号,可将复杂的信号直接分离成从高频到低频的若干阶固有模态函数。分析结果虽然没有表现出明显的频谱分布特性,但与以往HHT分析结果提取的固有模态函数不同,如果对该试验获得的非平稳信号提取的固有模态是低频部分的残余信号,忽略其他高频信号,则风压时程和升力系数时程的残余信号曲线就可以分别回归为一个线性函数和一个正弦函数。这也说明,该非平稳信号的主成分仍然是由平稳信号组成的,可以用分析平稳信号的方法进行时程分析。 | 赵杨 武岳 曹曙阳 段忠东 Yukio Tamura S. Ozono | 2011 | 振动与冲击2011，30，2： | 7 |
| 16 | Genotype-phenotype relationship in hereditary amyotrophic lateral sclerosis显示文摘Amyotrophic lateral sclerosis(ALS)is the most common adult-onset motor neuron disease.It is characterized by neuronal loss and degeneration of the upper motor neurons(UMNs)and lower motor neurons(LMNs),and is usually fatal due to respiratory failure within 3–5 years of onset.Although approximately 5–10%of patients with ALS have an inherited form of the disease,the distinction between hereditary and apparently sporadic ALS(SALS)seems to be artificial.Thus,genetic factors play a role in all types of ALS,to a greater or lesser extent.During the decade of upheaval,the evolution of molecular genetics technology has rapidly advanced our genetic knowledge about the causes of ALS,and the relationship between the genetic subtypes and clinical phenotype.In this review,we will focus on the possible genotype-phenotype correlation in hereditary ALS.Uncovering the identity of the genetic factors in ALS will not only improve the accuracy of ALS diagnosis,but may also provide new approaches for preventing and treating the disease. | Satoshi Yamashita Yukio Ando | 2015 | Translational Neurodegeneration2015，4，1： | 7 |
| 17 | 几种非平稳分析方法对非平稳风力时程的比较分析显示文摘非平稳信号的分析方法是信号分析领域中的一个重要问题。本文以风洞试验获得的非平稳风压信号和升力系数信号为研究对象,分别采用短时傅里叶变换、Wigner-Ville分布,小波变换方法和Hilbert-Huang变换(HHT)方法对信号进行时频分析。分析结果表明,由于短时傅里叶变换、Wigner-Ville分布,小波变换方法都是基于傅里叶变换,因此,得到的频谱特性都大致相同,只是在分析的精细程度上有所差异;HHT方法可以获得有意义的瞬时频率,从而给出频率随时间变化的精确表达,信号最终被表示为时频平面上的能量分布,成为Hilbert谱,该方法适用于分析生活中普遍存在的大量频率随时间变化的非线性、非平稳信号,可将复杂的信号直接分离成从高频到低频的若干阶固有模态函数。另一方面,无论用哪一种分析方法都可以看出,风速和风压信号的能量大多分布在低频部分,高频部分所占比例很少,而升力信号的能量大多分布在高频部分,低频部分所占比例很少。本文采用HHT方法提取起控制作用的信号主成分。 | 赵杨 曹曙阳 武岳 Tamura Yukio 段忠东 Ozono S. | 2011 | 土木工程学报2011，44，9： | 7 |
| 18 | 回廊 laparoscopic 胆囊炎: 在在日本的一所社区医院的天大小写对一夜的外科的审计显示文摘 AIM: To evaluate the applicability and safety of ambulatory laparoscopic cholecystectomy (LC) and to compare day case and overnight stay LC. METHODS: Data were collected retrospectively and consecutively for day case and overnight stay LC patients from July 1, 2009 to April 30, 2011. Outcomes were analyzed for patient demographics, operation time, blood loss during operation and frequency and reasons for unexpected or prolonged hospitalization in each group. RESULTS: There was no hospital mortality and no patient was readmitted with serious morbidity after discharge. 50 patients received a day case LC and 19 had an overnight stay LC. There was a significant difference in age between both groups (P<0.02). There were no significant differences between the day case LC performed (n=41) and failed (n=9) groups and between the day case LC performed and the one night stay LC (n=12) groups. There was a significant difference in age between the one night stay and more nights stay LC groups (P<0.05). Thus, elderly patients showed a tendency to like to stay in hospital rather than being a day case. The proportion of unexpected or prolonged hospitalization was not significantly different between the day case and overnight stay LC groups, when the patient’s request was excluded. CONCLUSION: Day case LC can be performed with a low rate of complications. In overnight stay patients, there are many who could be performed safely as a day case. Moreover, we need to take special care to treat elderly patients. | Atsushi Sato Yukio Terashita Yoichiro Mori Tomotaka Okubo | 2012 | World Journal of Gastrointestinal Surgery2012，4，12： | 7 |
| 19 | Three-dimensional imaging identified the accessory bile duct in a patient with cholangiocarcinoma显示文摘The development of diagnostic imaging technology, such as multidetector computed tomography(MDCT) and magnetic resonance cholangiopancreatography(MRCP), has made it possible to obtain detailed images of the bile duct. Recent reports have indicated that a 3-dimensional(3D) reconstructed imaging system would be useful for understanding the liver anatomy before surgery. We have investigated a novel method that fuses MDCT and MRCP images. This novel system easily made it possible to detect the anatomical relationship between the vessels and bile duct in the portal hepatis. In this report, we describe a very rare case of extrahepatic cholangiocarcinoma associated with an accessory bile duct from the caudate lobe connecting with the intrapancreatic bile duct. We were unable to preoperatively detect this accessory bile duct using MDCT and MRCP. However, prior to the second operation, we were able to clearly visualise the injured accessory bile duct using our novel 3D imaging modality. In thisreport, we suggest that this imaging technique can be considered a novel and useful modality for understanding the anatomy of the portal hepatis, including the hilar bile duct. | Ryoichi Miyamoto Yukio Oshiro Shinji Hashimoto Keisuke Kohno Kiyoshi Fukunaga Tatsuya Oda Nobuhiro Ohkohchi | 2014 | World Journal of Gastroenterology2014，20，32： | 6 |
| 20 | 近红外漫射光层析成像实验研究显示文摘实验验证了所建立的时间分辨光学层析成像测量系统的光学参量预测能力、多个测量通道的一致性,表明了本测量系统具有层析成像的潜力.研究了采用特征数据量(平均飞行时间、广义脉冲谱技术为基础的用数据类型R)及全时间分辨数据的图像重建算法在光学参量重建准确度、重建出的对象尺寸、空间分辨率等方面的各自优势. | 赵会娟 姜颖婷 缪辉 高峰 YUKARI Tanikawa YUKIO Yamada | 2007 | 光子学报2007，36，6： | 6 |
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