|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 血管周围脂肪组织中的Bmal1通过血管紧张素原转录调控管理静息期血压显示文摘血管周围脂肪组织(perivascular adipose tissue,PVAT)围绕血管,构成了在生理条件下保持血管张力所需的脉管系统的独特的功能整体层。然而,关于PVAT与血压调节之间的关系的资料很少,包括其对昼夜血压变化的潜在作用。 | Chang L Xiong W Zhao X Fan Y Guo Y Garcia-Barrio M Zhang J Jiang Z Lin JD Chen YE 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，2： | 23 |
| 2 | 桑叶多糖对早期断奶仔猪生长性能、腹泻、血液指标和肠道菌群的影响显示文摘研究旨在探讨日粮补充桑叶多糖(MLPs)对早期断奶仔猪生长性能、腹泻、血液生化指标和肠道菌群的影响。共选取(28±2)日龄、体重为(9.18±0.46)kg的'杜洛克×长白×约克夏'杂交断奶仔猪150头,随机分成5个处理组,每组6个重复,每个重复5头猪。饮食处理如下:对照组(CT):基础日粮(BD);低剂量桑叶多糖组(LT):0.3 g·kg-1MLPs+BD;中剂量桑叶多糖组(MT):0.6 g·kg-1MLPs+BD;高剂量桑叶多糖组(HT):0.9 g·kg-1MLPs+BD;抗生素处理组(AT):0.15 g·kg-1金霉素+BD。分别在第0、10、21天的早晨,每头猪空腹测量体重并记录采食量,这些数据用来计算平均日增重(ADG)、平均日采食量(ADFI)和料重比(F/G)。每天两次(上午和下午)对每头仔猪的腹泻状况进行检查并记录。在试验结束时,收集血液样本用于生化分析,并收集盲肠、结肠和直肠内容物进行识别和量化相关的肠道菌群。研究结果表明,MLPs处理组间的日增重、平均日采食量和料重比无显著差异(P>0.05),但低剂量组(LT)、中剂量组(MT)、高剂量组(HT)的平均日采食量高于对照组(CT)和抗生素组(AT)。并且,LT、MT和HT组的料重比低于CT和AT组。与CT和AT组相比,LT、MT和HT组仔猪的腹泻发病率也显著降低(P<0.05)。生化分析表明,MLPs各处理组仔猪的血糖(GLU)水平均显著低于CT或AT组(P<0.05)。MT和HT组血液尿素氮(BUN)水平与CT和AT组存在显著差异(P<0.05),HT组T3水平显著高于CT和AT组(P<0.05)。虽然MLPs各处理组的T4水平与AT组并没有显著差异(P>0.05),但MT组的胰岛素样生长因子Ⅰ(IGF-Ⅰ)和生长激素(GH)水平较CT或AT组均显著升高(P<0.05)。LT、MT和HT 3组在抑制肠道大肠杆菌生长和促进肠道乳酸杆菌和双歧杆菌生长的整体效果上均优于CT和AT组。值得注意的是,与CT和AT组相比,HT组(0.9 g·kg-1MLPs)对抑制肠道大肠杆菌以及促进肠道有益菌群具有更显著效果(P<0.05)。结果表明,日粮添加桑叶多糖可以改善早期断奶仔猪肠道菌群的生态环境,降低腹泻率,提高整体生长性能。 | Zhao X J Lin L Luo Q L Ye M Q Luo G Q Kuang Z S | 2015 | 饲料博览2015，0，7： | 7 |
| 3 | Age and menopausal status are important factors influencing the serum human epididymis secretory protein 4 level:a prospective cross-sectional study in healthy Chinese people显示文摘Background::Human epididymis secretory protein 4(HE4)is a new ovarian cancer biomarker.The factors influencing HE4 levels are not clear,and the reference data in China are limited.Here,we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chinese people.Methods::A total of 2493 healthy females aged 40 years or older were recruited from March 2013 to March 2017 with the cooperation of four medical institutions across Beijing,China.The serum levels of HE4 and cancer antigen 125(CA125)were measured by enzyme-linked immunosorbent assay.The Wilcoxon rank-sum test of variance and a stratified analysis were used to analyze the relationships among age,menopausal status,and levels of HE4 or CA125.Confidence intervals(5%-95%)were determined for reference ranges in different populations.Results::There was a statistically significant difference in median HE4 levels between the post-menopausal(n=2168)and premenopausal groups(n=325)(36.46 vs.24.04 pmol/L,Z=-14.41,P<0.001).HE4 increased significantly with age in the post-menopausal groups(H=408.18,P<0.001)but not in the pre-menopausal subjects(Z=-0.43,P=0.67).The upper 95th percentile of HE4 levels were 44.63 pmol/L for pre-menopausal women,78.17 pmol/L for post-menopausal women,and 73.3 pmol/L for all women.In the post-menopausal population,the HE4 reference ranges were 13.15 to 47.31,14.31 to 58.04,17.06 to 73.51,24.50 to 115.25,and 35.71 to 212.37 pmol/L for different age groups from forty divided by decade.The CA125 level was affected mainly by menopausal status and not age.Conclusions::Menopausal status and age were both important factors influencing the level of HE4,and age affected HE4 levels mainly in post-menopausal women.The HE4 level was higher in the post-menopausal population than in the pre-menopausal population and increased with age. | Hong-Yan Cheng Lin Zeng Xue Ye Rui-Qiong M a Zhi-Jian Tang Hong-Ling Chu Yi-M ing Zhao Li-Rong Zhu Yu-Nong Gao Xiao-Hong Chang Heng Cui | 2020 | Chinese Medical Journal2020，，11： | 6 |
| 4 | Predicting hepatitis B viruspositive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning显示文摘 | Ye QH Qin LX F orgues M | 2003 | Nat Med2003，9，4： | 3 |
| 5 | Entrepreneurs innovation bringing job satisfaction,work-family balance,and life satisfaction:In China and around the world显示文摘Entrepreneurs work such,as innovation,may bring financial benefits and non-pecuniary benefits,such as well-being.Entrepreneurial innovation expectedly benefits an individuals job satisfaction,balance between work and family,and life satisfaction.This is tested for entrepreneurs in China and around the world,with a globally representative sample of 33,519 entrepreneurs,including 786 in China.Among entrepreneurs around the world,innovation benefits job satisfaction,the balance between work and family,and life satisfaction.In China,specifically,entrepreneurs innovation also benefits their satisfaction with the balance between work and family and with life. | Kent Wickstrøm Jensen Ye Liu Thomas Schøtt | 2017 | International Journal of Innovation Studies2017，1，4： | 2 |
| 6 | Histone H3 lysine 4 monomethylation modulates long- range chromatin interactions at enhancers显示文摘在 enhancers 和倡导者之间的远程的染色质相互作用为在哺乳动物和另外的 metazoans 的许多发展地控制的基因的抄写是必要的。当前,把远侧的 enhancers 连接到他们的特定的目标倡导者的准确机制尚待充分被阐明。这里,我们证明 4 monomethylation (H3K4me1 )(MLL3/4 ) 和 histone methyltransferases MLL3 和 MLL4 玩的提高特定的 histone H3 离氨酸在这个过程的一个活跃角色。我们在区分老鼠表明那胚胎的干细胞,在 enhancers 的 H3K4me1 的 MLL3/4-dependent 免职与染色质相互作用的增加的层次相关,而这 histone 修正的损失在区别期间在基因激活导致染色质相互作用和缺点的减少的层次。H3K4me1 便于 Cohesin 建筑群的招募,染色质组织的一个已知的管理者到在 vitro 并且在 vivo 的染色质,提供潜在的机制让 MLL3/4 支持在 enhancers 和倡导者之间的染色质相互作用。一起拿,我们的结果在在哺乳动物的房间在 enhancers 安排远程的染色质相互作用为 MLL3/4-dependent H3K4me1 支持一个角色。 | Jian Yan Shi-An A Chen Andrea Local Tristin Liu Yunjiang Qiu Kristel M Dorighi Sebastian Preissl Chloe M Rivera Chaochen Wang Zhen Ye Kai Ge Ming Hu Joanna Wysocka Bing Ren | 2018 | Cell Research2018，28，2： | 2 |
| 7 | Synthesis and crystal structure of K4H2·18H2O显示文摘 | Ye SR Shan Y K He M Y | 2002 | Zeitschrift fur Kristallographie NCS2002，217，： | 2 |
| 8 | Valuation of Loss Firms In a Knowledge-based Economy 显示文摘 | DARROUGH M YE J | 2007 | Review of Accounting Studies2007，，12： | 1 |
| 9 | Type Ⅺ collagen-induced arthritis in the Lewis rat:characterization of cellular and humoral responsen to native Ⅺ,Ⅴ and Ⅱ collage and constituent a-chains显示文摘 | Ye X Terato K | 1994 | J Immunol1994，153，2： | 1 |
| 10 | 显示文摘 | Jagtoyen M Oksefjell T | 1991 | Mater Sci Forum1991，，： | 1 |
| 11 | Analysis of phenolic compounds in Rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry显示文摘 | Han J Chen HB | 2006 | J Am Soc Mass Spectrom2006，，： | 1 |
| 12 | Soil-surface CO2 efflux and its spatial and temporal variation in a young ponderosa pine plantation in northern California显示文摘 | Ye Q | 2001 | Glob Change Biol2001，7，： | 1 |
| 13 | Fluorescent microsphere-based readout technology for multiplexed human single nueleotide polymorphism analysis and bacterial identification 显示文摘 | Ye F Li M S Taylor J D | 2001 | Hum Murat2001，17，4： | 1 |
| 14 | Metal-organic molecular architectures with 2,2′-bipyridyl-like and carboxylate ligands显示文摘 | Ye B H Tong M L Chen X M | 2005 | Coord Chem Rev2005，249，： | 1 |
| 15 | A Unified Formulation for Hollow and Solid Concrete-Filled Steel Tube Columns Under Axial Compression显示文摘 | Yu M Zha X X Ye J | 2010 | Engineering Structures2010，32，： | 1 |
| 16 | Construction and co-expression of a polycistronic plasmid encoding carbonyl reductase and glucose dehydrogenase for production of ethyl (S)-4-chloro- 3-hydroxybutanoate显示文摘 | Ye Q Cao H Yan M | 2010 | Bioresour Technol2010，101，17： | 1 |
| 17 | Novel cytotoxic bufadienolides derived from bufalin by microbial hydroxylation and their structure-activity relationships 显示文摘 | Ye M Qu G Guo H | 2004 | J Steroid Biochem Mol Biol2004，91，12： | 1 |
| 18 | An energy efficient clustering scheme in wireless sensor networks显示文摘 | M Ye C F Li G H Chen J Wu | 2007 | International Journal of Ad Hoc & Sensor Wireless Networks2007，3，2： | 1 |
| 19 | Efficient production of vitamin B12 from propionic acid bacteria under periodic variation of dissolved oxygen concentration显示文摘 | Ye K Ship M Jin S | 1996 | J Ferment Bioeng1996，82，5： | 1 |
| 20 | Study on microhardness of bulk nanocrystalline copper 显示文摘 | YANG M C YE F SUN X K | 1997 | Nanostruetured Materials1997，9，48： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员