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1Finding of ancient materials in Cathaysia and implication for the formation of Precambrian crust显示文摘在 Nanxiongarea 从帕拉片麻岩为 56 由岩屑形成的锆石标明日期的 U-Pb,北广东省,显示在 Cathaysiahinterland 的最近的 Neoproterozoic 沉积由众多的 Grenvillian 和 Neoarchaean 组成碎屑状的材料,以及 someMesoproterozoic 岩屑。次要的 Paleoarchaean (3.76 Ga ) 和 Mesoarchaean (3.0—3.2 Ga ) 锆石,是在华南的最旧的锆石,第一也在沉积被发现,建议卡赛西亚·布洛克可以包含很旧的材料。thirty-sevenzircons 的 Hf 同位素作文表明这些碎屑状的材料有不同起源。次要的锆石从产生从的岩浆结晶相对少年外壳,当大多数锆石的父母岩浆从古老的外壳被导出时。U-Pb 标明日期和这些锆石的 Hf 同位素分析的集成建议在 Cathaysia 块的少年外壳的产生主要发生在 2.5 点—2.6Ga。Mesoarchaean (3.0—3.3 Ga ) ,迟了的 Paleoproterozoic (~ 1 .8 Ga ) 和 Paleoarchaean (~ 3 .7 Ga ) 可以也是外壳的生长的重要事件。Grenvillian magmatism 是极其强烈的,但是它主要涉及与少年外壳的很少形成古老的外壳的部件再循环。~ 2 .1 Ga Hf 模型年龄的 Themarked 存在和有结晶化的锆石的缺席在~ 2 .1 Ga 变老建议许多锆石的父母岩浆可能从由 Neoarchaean 和迟了的 Paleoproterozoic 材料组成的混合来源被导出。YU JinHai Y S O'REILLY WANG LiJuan W L GRIFFIN JIANG ShaoYong WANG RuCheng XU XiSheng 2007Chinese Science Bulletin2007,52,1:47
2Screening and analysis of the multiple absorbed bioactive components and metabolites of Dangguibuxue decoction by the metabolic fingerprinting technique and liquid chromatography/diode-array detection mass spectrometry显示文摘Wang, P Liang, YZ Zhou, N Chen, BM Yi, LZ Yu, Y Yi, ZB 2007中国生物学文摘2007,21,11:31
3Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X 2010南京医科大学学报(自然科学版)2010,30,8:25
4体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B 2020中华高血压杂志2020,28,3:22
5Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway.显示文摘Chert J Tang XQ Zhi JL Cui Y Yu HM Tang EH Sun SN Feng JQ Chen PX Chen J 2006中国生物学文摘2006,20,10:16
6Mutation analysis of the FOXL2 gene in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome显示文摘Tang SJ Wang XK Lin LX Sun Y Wang YL Yu HB 2006中国生物学文摘2006,20,4:15
7CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma显示文摘Xu Y Stamenkovic I Yu Q. 2010中国神经肿瘤杂志2010,8,1:14
8Factors predicting survival in patients with proximal gastric carcinoma involving the esophagus显示文摘AIM:To investigate the clinicopathologic features which predict surgical overall survival in patients with proximal gastric carcinoma involving the esophagus (PGCE).METHODS:Electronic pathology database established in the Department of Pathology of the Nanjing Drum Tower Hospital was searched for consecutive resection cases of proximal gastric carcinoma over the period from May 2004 through July 2009.Each retrieved pathology report was reviewed and the cases with tumors crossing the gastroesophageal junction line were selected as PGCE.Each tumor was re-staged,following the guidelines on esophageal adenocarcinoma,according to the 7th edition of the American Joint Commission on Cancer Staging Manual.All histology slides were studied along with the pathology report for a retrospective analysis of 13 clinicopathologic features,i.e.,age,gender,Helicobacter pylori (H.pylori ) infection,surgical modality,Siewert type,tumor Bormann's type,size,differentiation,histology type,surgical margin,lymphovascular and perineural invasion,and pathologic stage in relation to survival after surgical resection.Prognostic factors for overall survival were assessed with uniand multi-variate analyses.RESULTS:Patients' mean age was 65 years (range:47-90 years).The male:female ratio was 3.3.The 1-,3and 5-year overall survival rates were 87%,61% and 32%,respectively.By univariate analysis,age,male gender,H.pylori ,tumor Bormann's type,size,histology type,surgical modality,positive surgical margin,lymphovascular invasion,and pT stage were not predictive for overall survival;in contrast,perineural invasion (P = 0.003),poor differentiation (P = 0.0003),> 15 total lymph nodes retrieved (P = 0.008),positive lymph nodes (P = 0.001),and distant metastasis (P = 0.005) predicted poor post-operative overall survival.Celiac axis nodal metastasis was associated with significantly worse overall survival (P = 0.007).By multivariate analysis,≥ 16 positive nodes (P = 0.018),lymph node ratio > 0.2 (P = 0.003),and overall pathologic stage (P = 0.002) were independent predictors for poor overall survival after resection.CONCLUSION:Patients with PGCE showed worse overall survival in elderly,high nodal burden and advanced pathologic stage.This cancer may be more accurately staged as gastric,than esophageal,cancer.Yi-Fen Zhang Jiong Shi Hui-Ping Yu An-Ning Feng Xiang-Shan Fan Gregory Y Lauwers Hiroshi Mashimo Jason S Gold Gang Chen Qin Huang 2012World Journal of Gastroenterology2012,18,27:12
9Paleoproterozoic basement beneath the southern Jiangxi Province:Evidence from U-Pb ages and Lu-Hf isotopes in zircons from the Doushui lamprophyre显示文摘这篇论文论述侵入的煌斑岩的 geochemical 分析在 Shangyou 县的古苏格兰的 Doushui 花岗石身体,南部的江西省。U-Pb 标明日期和 Hf 同位素分析特别从它为锆石被执行。Petrological 和 geochemical 特征证明煌斑岩属于 high-K,弱碱的辉石黑云母煌斑岩。它被 Mg #(0.74 ) , Ni (253 μg/g ) 和 Cr (893 μg/g ) 满足的高度描绘,并且也在不兼容的元素充实,例如 REE, Rb, Sr, Ba 和 K。它的原语融化,这被建议可能由 non-crust-derived 源于充实的披风 metasomatized 代理人。在煌斑岩标明日期锆石的结果的形态学和 LAM-ICPMS 显示他们是从深外壳的岩石捕获的 xenocrysts。在 ∼1.86 Ga 形成的大多数 xenocrystic 锆石,和在不同 Phanerozoic 时期的一些。Paleoproterozoic 锆石具有 magmatic 起源并且有类似的 176Hf/177 Hf 和 176Lu/177 Hf 比率,显示他们可能从一样的火的地下室岩石。年龄和从这地下室岩石的锆石的 Hf 同位素作文类似于在南部的浙江省的 Paleoproterozoic Danzhu 花岗石的那些,但是极其与 Nanling 地下室区分开来,建议学习区域可能是一向西在东方卡赛西亚·布洛克的 Paleoproterozoic Wuyishan 岩层的延期部分。这些 Paleoproterozoic 锆石有低 Hf 同位素作文,外壳的来源特征。这些锆石的 Hf 模型年龄和在他们以内的更旧的继承核心的存在,结合了可得到的其它数据由以前的研究报导了,建议 Paleoproterozoic 岩浆的来源是 Neoarchaean 外壳,在 Wuyishan 岩层暗示更旧的地下室的存在。U-Pb 年龄和五 Phanerozoic 锆石的 Hf 同位素显示那个 Paleoproterozoic 地下室经历了多重做的发生在古苏格兰, Indosinian 和早 Yanshanian 分别地。古苏格兰的 magmatism 也涉及少年外壳重做。YU JinHai WANG LiJuan O'REILLY S Y SHU LiangShu SUN Tao 2009Chinese Science Bulletin2009,54,9:10
10Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined.Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu 2022Stroke & Vascular Neurology2022,7,1:7
11中国成人糖尿病、血糖与结直肠癌发病率:针对50万人的前瞻性研究显示文摘背景糖尿病可致结直肠癌(CRC)的发病风险升高。糖尿病病程和非糖尿病患者的血糖与CRC发病风险之间的相关性仍不清楚。方法2004至2008年前瞻性中国Kadoofe Biobank研究从10个不同地区纳入了512 713名受试者。在10年随访期间,在基线无癌症史的510 136名受试者中共记录有3 024例新发CRC病例(1 745例结肠癌,1 716例直肠癌)。应用Cox回归分析对糖尿病(入组前诊断或筛查发现的)或无糖尿病病史者随机血糖(RPG)水平与CRC发病相关性的校正风险比(HR)进行估计。结果基线时,共有5.8%的受试者患有糖尿病。糖尿病患者发生CRC的校正HR为1.18(95%可信区间1.04~1.33),且发生结肠癌与直肠癌的风险相当[1.19(1.01~1.39)比1.14(0.96~1135)]。这些患者发生CRC的HR随糖尿病病程的延长而下降(趋势P值为0.03)。在入组前无糖尿病的受试者中,其RPG水平与CRC发病呈正相关,基线RPG每升高1 mmol/L其发生CRC的校正HR为1.04(1.02~1.05),且发生结肠癌与直肠癌的风险亦相当[1.03(1.01~1.05)比1.04(1.02~1.06)]。在男性中,糖尿病和RPG与CRC发病风险的相关性高于女性,但其差异无统计学意义(异质性检验的P值分别为0.3和0.2)。讨论在中国成年人中,未诊断糖尿病者其糖尿病和升高的血糖水平与CRC发病风险升高相关。Yuanjie Pang Christiana Kartsonak yu Guo Yiping Chen Ling Yang Zheng Bian Fiona Bragg Iona Y Millwood Leijia Shen Songgen Zhou Jiben Liu Junshi Chen Liming Li Michael V Holmes Zhengming Ghen 霍永丰(译) 2019英国医学杂志中文版2019,22,1:6
12肠系膜下动脉根部淋巴结清扫联合血管低位或高位结扎治疗直肠癌的效果观察显示文摘目的:在结直肠癌手术中,与肠系膜下动脉高位结扎相比,保留左结肠动脉的低位结扎在淋巴结清扫、吻合口漏和肿瘤学结果方面仍存在争议。本研究通过回顾性病例分析探讨腹腔镜直肠癌前切除术中肠系膜下动脉高位结扎或低位结扎对患者近期和远期疗效的影响。方法:回顾性分析2013年至2016年在仁济医院行腹腔镜直肠癌前切除术的614例患者的临床资料,比较低位结扎组和高位结扎组的临床人口学特征、手术时间、IMA根部淋巴结清扫数目、围手术期并发症、术后3年和术后5年的总生存率和无病生存率。两组之间比较采用t检验或χ^(2)检验,生存率采用Kaplan-Meier生存曲线以及Log-rank检验分析。以P<0.05为差异有统计学意义。孙凌宇 俞旻皓 骆洋 LUO Y YU M H HUANG Y Z 2021结直肠肛门外科2021,27,4:6
13Role of stem cell therapies in treating chronic wounds:A systematic review显示文摘BACKGROUND The impairment of cutaneous wound healing results in chronic,non-healing wounds that are caused by altered wound environment oxygenation,tissue injury,and permissive microbial growth.Current modalities for the treatment of these wounds inadequately address the complex changes involved in chronic wound pathogenesis.Consequently,stem cell therapies have emerged as a potential therapeutic modality to promote cutaneous regeneration through trophic and paracrine activity.AIM To investigate current literature regarding use of stem cell therapies for the clinical treatment of chronic,non-healing wounds.METHODS PubMed,EMBASE,Cochrane Library,Web of Science,and Scopus were queried with combinations of the search terms“mesenchymal stem cells,”“adult stem cells,”“embryonic stem cells,”“erythroid precursor cells,”“stem cell therapies,”and“chronic wounds”in order to find relevant articles published between the years of 2000 and 2019 to review a 20-year experience.Reference lists from the articles were reviewed to identify additional pertinent articles.Retrieved manuscripts(reviews,case reports/series,retrospective/prospective studies,and clinical trials)were evaluated by the authors for their depiction of clinical stem cell therapy use.Data were extracted from the articles using a standardized collection tool.RESULTS A total of 43 articles describing the use of stem cell therapies for the treatment of chronic wounds were included in this review.While stem cell therapies have been explored in in vitro and in vivo applications in the past,recent efforts are geared towards assessing their clinical role.A review of the literature revealed that adipose-derived stem cells,bone marrow-derived stem cells,bone marrowderived mononuclear cells,epidermally-derived mesenchymal stem cells,fibroblast stem cells,keratinocyte stem cells,placental mesenchymal stem cells,and umbilical cord mesenchymal stem cells have all been employed in the treatment of chronic wounds of various etiologies.Most recently,embryonic stem cells have emerged as a novel stem cell therapy with the capacity for multifaceted germ cell layer differentiation.With the capacity for self-renewal and differentiation,stem cells can enrich existing cell populations in chronic wounds in order to overcome barriers impeding the progression of wound healing.Further,stem cell therapies can be utilized to augment cell engraftment,signaling and activity,and resultant patient outcomes.CONCLUSION Assessing observed clinical outcomes,potential for stem cell use,and relevant therapeutic challenges allows wound care stakeholders to make informed decisions regarding optimal treatment approaches for their patients’chronic wounds.Anjali C Raghuram Roy P Yu Andrea Y Lo Cynthia J Sung Melissa Bircan Holly J Thompson Alex K Wong 2020World Journal of Stem Cells2020,12,7:5
14Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation显示文摘The objectives of this study were to(1) determine the distribution and synthesis of pericellular matrix(PCM) molecules(collagen VI, collagen IV and laminin) in rat temporomandibular joint(TMJ) and(2) investigate the effects of PCM molecules on chondrocytes against inflammation in osteoarthritis. Four zones(fibrous, proliferating, mature and hypertrophic) of condylar cartilage and three bands(anterior, intermediate and posterior) of disc were analysed by immunohistochemistry for the presence of PCM molecules in rat TMJs. Isolated chondrocytes were pre-treated with PCM molecules before being subjected to interleukin(IL)-1β treatment to stimulate inflammation. The responses of the chondrocytes were analysed using gene expression, nitric oxide release and matrix metalloproteinase(MMP)-13 production measures. Histomorphometric analyses revealed that the highest areal deposition of collagen VI(67.4%), collagen IV(45.7%) and laminin(52.4%) was in the proliferating zone of TMJ condylar cartilage. No significant difference in the distribution of PCM molecules was noted among the three bands of the TMJ disc. All three PCM molecules were expressed intracellularly by chondrocytes cultured in the monolayer. Among the PCM molecules, pre-treatment with collagen VI enhanced cellular proliferation, ameliorated IL-1β-induced MMP-3, MMP-9, MMP-13 and inducible nitric oxide synthase gene expression, and attenuated the downregulation of cartilage matrix genes, including collagen I, aggrecan and cartilage oligomeric matrix protein(COMP). Concurrently, collagen VI pretreatment inhibited nitric oxide and MMP-13 production. Our study demonstrates for the first time the distribution and role of PCM molecules, particularly collagen VI, in the protection of chondrocytes against inflammation.Wern Cui Chu Shipin Zhang Timothy J Sng Yu Jie Ong Wen-Li Tan Vivien Y Ang Casper B Foldager Wei Seong Toh 2017International Journal of Oral Science2017,9,1:5
15婴幼儿血管瘤的位置是消退后体积后遗症的预测因子显示文摘尽管婴幼儿血管瘤(IH)能够自行消退,但有些血管瘤的体积后遗症比其他的更多。确定这种后遗症的预测因子将为IH病变提供治疗参考,并有助于获得有利的疗效。本研究旨在探讨IH消退后剩余的体积残留与其位置之间的相关性,并确定其他潜在的结果预测因子。回顾2008-2011年治疗的所有IH患者,通过比较随访照片和最大尺寸病变的照片,获得消退后的体积残留程度和后遗症的量化指标。发现对于初次就诊的儿童,面部周围区域的病变比面部中央(P<0.0001)和胸部区域(P=0.0002)的病变消退更加显著。初次就诊年龄和病变类型一致时,面部周围病变的美学评分显著高于面部中央区域(P<0.0001)、胸部(P<0.0001)和躯干/四肢(P=0.0226)。本研究表明,初次就诊时的病变部位和年龄是造成体积后遗症和复发后病变美学的因素。本研究的结果为指导治疗决策提供了参考。赵泽亮 Chang SJ Yu W Gu Y 2019中国口腔颌面外科杂志2019,17,3:4
16Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC.Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. 2011World Journal of Gastroenterology2011,17,34:3
17Links among Slope Morphology, Canyon Types and Tectonics on Passive and Active Margins in the Northernmost South China Sea显示文摘We examine slope profile types and variations in slope gradient and slope relief with depth for both passive and active margins in the northern most South China Sea. The passive South China margin is characterized by an exponential slope profile, mainly associated with clustered slope-confined canyons. The active Taiwan margin shows a linear-like shape with great variations along the lower slope. Fewer canyons occur on the Taiwan margin, and hence the influence of canyon incision on slope morphology is relatively less significant. Quantitative analyses of slope curvature, slope gradi-ent and square root of relief variance are useful statistical parameters to explain characteristics and variability of morphology of the slope of the South China margin, but not for the Kaoping slope on the Taiwan side. On the active Taiwan margin, tectonic activities are dominant over sediment deposition and surface erosion, producing a slope profile quite different from those of passive margins of the Mid-dle Atlantic, KwaZulu-Natal, South Africa where failure on slope and accompanying canyon incision are the dominant processes shaping the slope morphology.Ho-Shing Yu Emmy T Y Chang 2009Journal of China University of Geosciences2009,20,1:3
18The genetic heterozygosity and fitness of tetraploid embryos and embryonic stem cells are crucial parameters influencing survival of mice derived from embryonic stem cells by tetraploid embryo aggregation显示文摘Li X Wei W Yong J Jia Q Yu Y Di K 2006中国生物学文摘2006,20,7:3
19Three-dimensional finite element simulation of curing of polymer composites显示文摘A Cheung Y Yu K Pochiraju 2003Finite Elements in Analysis & Design2003,,8:3
20不同支架中浓缩生长因子的细胞因子释放动力学显示文摘目的:浓缩生长因子(CGF)表现出更好的牙周组织再生潜力,然而,关于CGF随时间的释放模式知之甚少。本研究旨在研究脱蛋白牛骨矿物质(DBBM)和纤维内矿化胶原蛋白(IMC)中CGF生长因子和细胞因子的体外释放模式。材料与方法:将CGF、CGF与DBBM(CGF-DBBM)混合物,CGF与IMC(CGF-IMC)混合物体外培养28d,分别于24h、72h以及7、14、21、28d后收集培养基上清液。Yu M Wang X Liu Y 赵泽亮 2018中国口腔颌面外科杂志2018,16,5:3
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