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5篇 您的检索式:作者名="Xueman Liu"
    题名 作者 年代 出处 被引量
1New language outcome measures for Mandarin speaking children with hearing loss显示文摘Objective:The paper discusses recent evidence on the assessment of language outcomes in children with hearing loss acquiring oral language.Methods:Research emphasizes that language tests must be specific enough to capture subtle deficits in vocabulary and grammar learning at different developmental ages.The Diagnostic Receptive and Expressive Assessment of Mandarin(DREAM) was carefully designed to be a comprehensive standardized Mandarin assessment normed in China's Mainland.Objective:The paper discusses recent evidence on the assessment of language outcomes in children with hearing loss acquiring oral language.Methods:Research emphasizes that language tests must be specific enough to capture subtle deficits in vocabulary and grammar learning at different developmental ages.The Diagnostic Receptive and Expressive Assessment of Mandarin(DREAM)was carefully designed to be a comprehensive standardized Mandarin assessment normed in China's Mainland.Results:This paper summarizes the evidence-based item design process and validity and reliability results of DREAM.A pilot study reported here shows that DREAM provided detailed information about hearing impaired children's language abilities and can be used to aid intervention planning to maximize progress.Conclusion:DREAM represents an example of translational science,transferring methods from empirical studies of language acquisition in research environments into applied domains such as assessment and intervention.Research on outcomes in China will advance significantly with the availability of evidence-based comprehensive language tests that measure a sufficient age range of skills,are normed on Mandarin speaking children in China's Mainland,and are designed to capture features central to Mandarin language acquisition.Xueman Liu Jill de Villiers Wendy Lee Chunyan Ning Eric Rolfhus Teresa Hutchings Fan Jiang Yiwen Zhang 2016Journal of Otology2016,11,1:4
2Design of a 3-DOF PKM module for large structural component machining显示文摘Li Yonggang Liu Haitao Zhao Xueman 2010Mechanism and Machine Theory2010,45,6:1
3Current trends in outcome studies for children with hearing loss and the need to establish a comprehensive framework of measuring outcomes in children with hearing loss in China显示文摘Since the 1970 s, outcome studies for children with hearing loss expanded from focusing on assessing auditory awareness and speech perception skills to evaluating language and speech development. Since the early 2000 s, the multi-center large scale research systematically studied outcomes in the areas of auditory awareness, speech-perception, language development, speech development, educational achievements,cognitive development, and psychosocial development. These studies advocated the establishment of baseline and regular follow-up evaluations with a comprehensive framework centered on language development. Recent research interests also include understanding the vast differences in outcomes for children with hearing loss, understanding the relationships between neurocognitive development and language acquisition in children with hearing loss, and using outcome studies to guide evidence-based clinical practice. After the establishment of standardized Mandarin language assessments, outcomes research in China's Mainland has the potential to expand beyond auditory awareness and speech perception studies.Xueman Liu 2016Journal of Otology2016,11,2:1
4Designof a 3-DOF PKM module for large structural componentmachining显示文摘Li Yonggang Liu Haitao Zhao Xueman 2010Mechanism and Machine Theory2010,45,6:1
5Mammary stem cells:angels or demons in mammary gland?显示文摘A highly dynamic development process exits within the epithelia of mammary gland,featuring morphogenetic variation during puberty,pregnancy,lactation,and regression.The identification of mammary stem cells(MaSCs)via lineage-tracing studies has substantiated a hierarchical organization of the mammary epithelia.A single MaSC is capable of reconstituting the entirely functional mammary gland upon orthotopic transplantation.Although different mammary cell subpopulations can be candidate cells-of-origin for distinct breast tumor subtypes,it still lacks experimental proofs whether MaSCs,the most primitive cells,are the‘seeds’of malignant transformation during most,if not all,tumorigenesis in the breast.Here,we review current knowledge of mammary epithelial hierarchy,highlighting the roles of mammary stem/progenitor cells and breast cancer stem cells(BCSCs)along with their key molecular regulators in organ development and cancer evolution.Clarifying these issues will pave the way for developing novel interventions toward stem/progenitor cells in either prevention or treatment of breast cancer(BrCa).Xueman Chen Qiang Liu Erwei Song 2017Signal Transduction and Targeted Therapy2017,2,1:0
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