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| 1 | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines显示文摘SARS-CoV-2 variants could induce immune escape by mutations on the receptor-binding domain(RBD)and N-terminal domain(NTD).Here we report the humoral immune response to circulating SARS-CoV-2 variants,such as 501Y.V2(B.1.351),of the plasma and neutralizing antibodies(NAbs)elicited by CoronaVac(inactivated vaccine),ZF2001(RBD-subunit vaccine)and natural infection.Among 86 potent NAbs identified by high-throughput single-cell VDJ sequencing of peripheral blood mononuclear cells from vaccinees and convalescents,near half anti-RBD NAbs showed major neutralization reductions against the K417N/E484K/N501Y mutation combination,with E484K being the dominant cause.VH3-53/VH3-66 recurrent antibodies respond differently to RBD variants,and K417N compromises the majority of neutralizing activity through reduced polar contacts with complementarity determining regions.In contrast,the 242–244 deletion(242–244Δ)would abolish most neutralization activity of anti-NTD NAbs by interrupting the conformation of NTD antigenic supersite,indicating a much less diversity of anti-NTD NAbs than anti-RBD NAbs.Plasma of convalescents and CoronaVac vaccinees displayed comparable neutralization reductions against pseudo-and authentic 501Y.V2 variants,mainly caused by E484K/N501Y and 242–244Δ,with the effects being additive.Importantly,RBD-subunit vaccinees exhibit markedly higher tolerance to 501Y.V2 than convalescents,since the elicited anti-RBD NAbs display a high diversity and are unaffected by NTD mutations.Moreover,an extended gap between the third and second doses of ZF2001 leads to better neutralizing activity and tolerance to 501Y.V2 than the standard three-dose administration.Together,these results suggest that the deployment of RBD-vaccines,through a third-dose boost,may be ideal for combating SARS-CoV-2 variants when necessary,especially for those carrying mutations that disrupt the NTD supersite. | Yunlong Cao Ayijiang Yisimayi Yali Bai Weijin Huang Xiaofeng Li Zhiying Zhang Tianjiao Yuan Ran An Jing Wang Tianhe Xiao Shuo Du Wenping Ma Liyang Song Yongzheng Li Xiang Li Weiliang Song Jiajing Wu Shuo Liu Xuemei Li Yonghong Zhang Bin Su Xianghua Guo Yangyang Wei Chuanping Gao Nana Zhang Yifei Zhang Yang Dou Xiaoyu Xu Rui Shi Bai Lu Ronghua Jin Yingmin Ma Chengfeng Qin Youchun Wang Yingmei Feng Junyu Xiao Xiaoliang Sunney Xie | 2021 | Cell Research2021，31，7： | 12 |
| 2 | Epigenetic Modifications of mRNA and DNA in Plants显示文摘Advances in the detection and mapping of messenger RNA(mRNA)N^6-methyladenosine(m 6A)and 5-methylcytosine(m 5C),and DNA N^6-methyldeoxyadenosine(6mA)redefined our understanding of these modifications as additional tiers of epigenetic regulation.In plants,the most prevalent internal mRNA modifications,m^6A and m^5C,play crucial and dynamic roles in many processes,including embryo development,stem cell fate determination,trichome branching,leaf morphogenesis,floral transition,stress responses,fruit ripening,and root development.The newly identified and widespread epigenetic marker 6mA DNA methylation is associated with gene expression,plant development,and stress responses.Here,we review the latest research progress on mRNA and DNA epigenetic modifications,including the detection,dynamics,distribution,functions,regulatory proteins,and evolution,with a focus on m^6A,m^5C,and 6mA.We also provide some perspectives on future research of the newly identified and unknown epigenetic modifications of mRNA and DNA in plants. | Zhe Liang Adeel Riaz Sadaruddin Chachar Yike Ding Hai Du Xiaofeng Gu | 2020 | Molecular Plant2020，13，1： | 12 |
| 3 | Application of joint elastic impedance inversion in the GD Oilfield显示文摘为对 GD 油矿的复杂水库描述, P 波浪和 S 波浪有弹性的阻抗倒置被执行用预先叠精确地识别水库的岩性学的地震数据。联合倒置用三被执行或克服不能满足复杂水库描述的要求的栈以后的地震倒置的奇特并且避免倒置结果的不稳定性的更偏爱的栈在预先叠集合由低信号噪音比率引起了。prestack 橡皮阻抗倒置的基本理论简短在这篇论文被描述,用 GD 油矿的真实数据,钥匙角度集合小浪抽取,地平线刻度, S 波浪速度预言,和有弹性的参数抽取走被分析并且学习。从日志分析决定的多重有弹性的参数的全面解释是改进 prestack 的效果的关键地震倒置。 | Dai Xiaofeng Gan Lideng Du Wenhui Wang Ping | 2006 | Applied Geophysics2006，3，1： | 11 |
| 4 | Low-mature gases and typical low-mature gas fields in China显示文摘No natural gas pool of industrial importance could be formed at the low-evolution stage of organic matter. In the 1980s, on the basis of the development in exploration practice, the hypotheses of bio-thermo-catalytic transitional zone gases and early thermogenic gases were proposed. The lower-limit Ro values for the formation and accumulation of natural gases of industrial importance have been expanded to 0.3%―0.4%. In the light of the two-stage model established on the basis of carbon isotope fractionation in coal-type natural gases, the upper-limit Ro values have been set at 0.8%―1.0%. In terms of the geological practice in the low-mature gas zones and China's main coal-type gas fields, it is feasible and proper to set the upper-limit Ro value of low-mature gases at 0.8%. Supper-large gas fields such as the Urengoy gas field in western Siberian Basin should belong to low-mature gas fields, of which the natural gas reserves account for more than 20% of the global proven reserves, providing strong evidence for the significance of such a type of resources. The proven natural gas reserves in the Turpan-Hami Basin of China have almost reached 1000 × 108 m3. The main source rocks in this area are the Jurassic Xishanyao Formation, which occurs as a suite of coal series strata. The corresponding thermal evolution indices (Ro ) are mainly within the range of about 0.4%―0.8%, the δ 13C1 values of methane vary between-44‰ and-39‰ (correspondingly Ro =0.6%―0.8%), and those of ethane are within the range of-29‰―-26‰, indicating that natural gases in the Turpan-Hami Basin should be designated to coal-type low-mature gases. The light hydrocarbon evolution indices of natural gases also fall within the area of low evolution while the precursor type of light hydrocarbons also shows the characteristics of the coal-type. The geological background, carbon isotopic composition and light hydrocarbon index all provide strong evidence suggesting that the proven natural gases in the Turpan-Hami Basin are low-mature gases. In China a gas field with the gas reserves reaching 300 ×108 m3 can be defined as a large gas field, and thus the proven low-mature gases in the Turpan-Hami Basin are equivalent to the reserves of three large gas fields. Its existence is of great significance in research on and exploration of low-mature gases in China. | XU YongChang WANG ZhiYong WANG XiaoFeng ZHENG JianJing DU HongYu | 2008 | Science China Earth Sciences2008，51，2： | 11 |
| 5 | Transcriptional landscape of rice roots at the single-cell resolution显示文摘There are two main types of root systems in flowering plants,namely taproot systems of dicots and fibrous root systems found in monocots.Despite this fundamental split,our current knowledge of cellular and molecular mechanism driving root development is mainly based on studies of the dicot model Arabidopsis.However,the world major crops are monocots and little is known about the transcriptional programs underlying cell-type specification in this clade.Here,we report the transcriptomes of more than 20000 single cells derived from root tips of two agronomically important rice cultivars.Using combined computational and experimental analyses we were able to robustly identify most of the major cell types and define novel cell-type-specific marker genes for both cultivars.Importantly,we found divergent cell types associated with specific regulatory programs,including phytohormone biosynthesis,signaling,and response,which were well conserved between the two rice cultivars.In addition,we detected substantial differences between the cell-type transcript profiles of Arabidopsis and rice.These species-specific features emphasize the importance of analyzing tissues across diverse model species,including rice.Taken together,our study provides insight into the transcriptomic landscape of major cell types of rice root tip at single-cell resolution and opens new avenues to study cell-type specification,function,and evolution in plants. | Qing Liu Zhe Liang Dan Feng Sanjie Jiang Yifan Wang Zhuoying Du Ruoxi Li Guihua Hu Pingxian Zhang Yanfei Ma Jan ULohmann Xiaofeng Gu | 2021 | Molecular Plant2021，14，3： | 9 |
| 6 | Development and validation of an ocean wave retrieval algorithm for VV-polarization Sentinel-1 SAR data显示文摘The purpose is to study the accuracy of ocean wave parameters retrieved from C-band VV-polarization Sentinel-1Synthetic Aperture Radar(SAR) images, including both significant wave height(SWH) and mean wave period(MWP), which are both calculated from a SAR-derived wave spectrum. The wind direction from in situ buoys is used and then the wind speed is retrieved by using a new C-band geophysical model function(GMF) model,denoted as C-SARMOD. Continuously, an algorithm parameterized first-guess spectra method(PFSM) is employed to retrieve the SWH and the MWP by using the SAR-derived wind speed. Forty–five VV-polarization Sentinel-1 SAR images are collected, which cover the in situ buoys around US coastal waters. A total of 52 subscenes are selected from those images. The retrieval results are compared with the measurements from in situ buoys. The comparison performs good for a wind retrieval, showing a 1.6 m/s standard deviation(STD) of the wind speed, while a 0.54 m STD of the SWH and a 2.14 s STD of the MWP are exhibited with an acceptable error.Additional 50 images taken in China's seas were also implemented by using the algorithm PFSM, showing a 0.67 m STD of the SWH and a 2.21 s STD of the MWP compared with European Centre for Medium-range Weather Forecasts(ECMWF) reanalysis grids wave data. The results indicate that the algorithm PFSM works for the wave retrieval from VV-polarization Sentinel-1 SAR image through SAR-derived wind speed by using the new GMF C-SARMOD. | LIN Bo SHAO Weizeng LI Xiaofeng LI Huan DU Xiaoqing JI Qiyan CAI Lina | 2017 | Acta Oceanologica Sinica2017，36，7： | 7 |
| 7 | Optical observations of LIGO source GW 170817 by the Antarctic Survey Telescopes at Dome A,Antarctica显示文摘The LIGO detection of gravitational waves(GW) from merging black holes in 2015 marked the beginning of a new era in observational astronomy. The detection of an electromagnetic signal from a GW source is the critical next step to explore in detail the physics involved. The Antarctic Survey Telescopes(AST3),located at Dome A, Antarctica, is uniquely situated for rapid response time-domain astronomy with its continuous night-time coverage during the austral winter. We report optical observations of the GW source(GW 170817) in the nearby galaxy NGC 4993 using AST3. The data show a rapidly fading transient at around 1 day after the GW trigger, with the i-band magnitude declining from 17:23 ± 0:13 magnitude to 17:72 ± 0:09 magnitude in ~1:8 h. The brightness and time evolution of the optical transient associated with GW 170817 are broadly consistent with the predictions of models involving merging binary neutron stars. We infer from our data that the merging process ejected about ~10^(-2) solar mass of radioactive material at a speed of up to 30% the speed of light. | lei hu xuefeng wu igor andreoni michael c.b.ashley jeff cooke xiangqun cui fujia du zigao dai bozhong gu yi hu haiping lu xiaoyan li zhengyang li ensi liang liangduan liu bin ma zhaohui shang tianrui sun n.b.suntzeff charling tao syed a.uddin lifan wang xiaofeng wang haikun wen di xiao jin xu ji yang shihai yang xiangyan yuan hongyan zhou hui zhang jilin zhou zonghong zhu | 2017 | Science Bulletin2017，62，21： | 6 |
| 8 | Multiple effects of nitrate amendment on the transport, transformation and bioavailability of antimony in a paddy soil-rice plant system显示文摘Nitrate(NO3^(-))is known to be actively involved in the processes of mineralization and heavy metal transformation;however,it is unclear whether and how it affects the bioavailability of antimony(Sb)in paddy soils and subsequent Sb accumulation in rice.Here,the effects of NO3^(-)on Sb transformation in soil-rice system were investigated with pot experiments over the entire growth period.Results demonstrated that NO3^(-)reduced Sb accumulation in brown rice by 15.6%compared to that in the control.After amendment with NO3^(-),the Sb content in rice plants increased initially and then gradually decreased(in roots by 46.1%).During the first 15 days,the soil p H increased,the oxidation of Sb(Ⅲ)and sulfides was promoted,but the reduction of iron oxide minerals was inhibited,resulting in the release of adsorbed and organic-bound Sb from soil.The microbial arsenite-oxidizing marker gene aox B played an important role in Sb(Ⅲ)oxidation.From days 15 to 45,after NO3^(-)was partially consumed,the soil p H decreased,and the reductive dissolution of Fe(Ⅲ)-bearing minerals was enhanced;consequently,iron oxide-bound Sb was transformed into adsorbed and dissolved Sb species.After day 45,NO3^(-)was completely reduced,Sb(V)was evidently reduced to Sb(Ⅲ),and green rust was generated gradually.Thus,the available Sb decreased due to its enhanced affinity for iron oxides.Moreover,NO3^(-)inhibited the reductive dissolution of iron minerals,which ultimately caused low Sb availability.Therefore,NO3^(-)can chemically and biologically reduce the Sb availability in paddy soils and alleviate Sb accumulation inrice.This study provides a potential strategy for decreasing Sb accumulation in rice in the Sb-contaminated sites. | Xiaofeng Zhang Tongxu Liu Fangbai Li Xiaomin Li Yanhong Du Huanyun Yu Xiangqin Wang Chuanpin Liu MiFeng Bing Liao | 2021 | Journal of Environmental Sciences2021，33，2： | 6 |
| 9 | Numerical Investigation of an Oscillating Airfoil using Immersed Boundary Method显示文摘Based on the immersed boundary method,a numerical simulation for an oscillating airfoil is established and a preliminary analysis of the oscillating airfoil is presented with an emphasis on the physical understanding of fluid-structure interaction.In order to validate the method,two simulation cases:oscillating circular cylinder at low K-C number and two degrees of freedom oscillating cylinder are carried out first and the results are in good agreement with the previous researches.In the oscillating airfoil simulation,it is found that the reduced velocity U* is a very sensitive factor and especially U*~2.8 is the critical stable boundary in the present work.The method shows the predominance of time saving in computational process for such a complicated fluid-structure interaction problem. | Guohua Zhong Lin Du Xiaofeng Sun | 2011 | Journal of Thermal Science2011，20，5： | 5 |
| 10 | Engineering nerve guidance conduits with three-dimenisonal bioprinting technology for long gap peripheral nerve regeneration显示文摘Nerve guidance conduits (NGCs) are tubular structures that are used to bridge the gap of a severed nerve, thereby acting as a guide and protective micro-environment for the regenerating axons and as a barrier against the in-growth of scar-forming tissue. In the last few decades, the concept of NGCs has evolved from a research tool to investigate nerve regeneration into a translational product that is now being used clinically as an alternative for autologous nerve graft repair, due to their availability and ease of fabrication. | Jian Du Xiaofeng Jia | 2019 | Neural Regeneration Research2019，14，12： | 4 |
| 11 | Petrology,Geochemistry,and Sr-Nd-S Isotopic Compositions of the Ore-Hosting Biotite Monzodiorite in the Luanjiahe Gold Deposit,Jiaodong Peninsula,China显示文摘The Jiaodong Peninsula is one of the most important Au ore provinces in China.There is an ongoing debate on the correlation between ore formation and magmatism in this province,because few intrusive rocks exhibit a clear association with ore deposits.A mineralized biotite monzodiorite(BM)stock,with disseminated ore,pervasive phyllic alteration,and no deformation,was found in a borehole in the footwall of the Zhaoping fault within the Luanjiahe Au deposit,which may shed light on this debate.The biotite monzodiorite contains explosion breccias,miarolitic cavities,skeletal and den-dritic quartz,and late-stage evolved aplite dikes,and the in-situδ34S values of the disseminated pyrite which is associated with Au mineralization are-1.7‰ to 7.3‰(mean=3.5‰),indicative of a magmatic-hydrothermal system.These findings,combined with the reported age of 123 Ma,show that the intru-sion has close spatial,temporal,and geochemical relationships with Au mineralization in the area.The biotite monzodiorite is metaluminous,high-K calc-alkaline and shoshonitic,with enrichment in light rare earth elements(REEs)and large-ion lithophile elements(LILEs),depletion in high-field-strength elements(HFSEs),and enriched Sr-Nd isotopic compositions.The intrusion may be the product of par-tial melting of enriched lithospheric mantle with a small lower crustal component.The hydrous,Au-bearing,enriched mantle source,and the strongly oxidized magma that was generated,created fa-vorable conditions for Au mineralization. | Xiaofeng Yao Zhizhong Cheng Zezhong Du Zhenshan Pang Yuquan Yang Kun Liu | 2021 | Journal of Earth Science2021，32，1： | 4 |
| 12 | Tensile, creep behavior and microstructure evolution of an as-cast Ni-based K417G polycrystalline superalloy显示文摘The Ni-based K417 G superalloy is extensively applied as aeroengine components for its low cost and good mid-temperature(600–900?C) properties. Since used in as-cast state, the comprehensive understanding on its mechanical properties and microstructure evolution is necessary. In the present research,the tensile, creep behavior and microstructure evolution of the as-cast K417 G superalloy under different conditions were investigated. The results exhibit that tensile cracks tend to initiate at MC carbide and γ/γ' eutectic structure and then propagate along grain boundary. As the temperature for tensile tests increases from 21?C to 700?C, the yield strength and ultimate tensile strength of K417 G superalloy decreases slightly, while the elongation to failure decreases greatly because of the intermediate temperature embrittlement. When the temperature rises to 900?C, the yield strength and ultimate tensile strength would decrease significantly. The creep deformation mechanism varies under different testing conditions. At 760?C/645 MPa, the creep cracks initiate at MC carbides and γ/γ' eutectic structures,and propagate transgranularly. While at 900?C/315 MPa and 950?C/235 MPa, the creep cracks initiate at grain boundary and propagate intergranularly. As the creep condition changes from 760?C/645 MPa to 900?C/315 MPa and 950?C/235 MPa, the ? phase starts to raft, which reduces the creep deformation resistance and increases the steady-state deformation rate. | Beining Du Ziyang Hu Liyuan Sheng Chuanyong Cui Jinxia Yang Yufeng Zheng Xiaofeng Sun | 2018 | Journal of Materials Science & Technology2018，34，10： | 4 |
| 13 | Correlations of PCBs, DIOXIN, and PBDE with TSH in Children's Blood in Areas of Computer E-waste Recycling显示文摘Objective To study correlations of polychlorinated biphenyls (PCBs), DIOXIN, and polybrominated diphenyl ethers (PBDE) with thyroid stimulating hormone(TSH) in children, and assess the impact on children's health. Methods Three hundred and sixty nine children aged from 6 to 8, including 195 from Luqiao, the computer E‐waste recycling area, and 174 from Longyou, the control area, were selected for this investigation to elucidate the correlation of PCBs, DIOXIN, and PBDE with TSH in children's blood samples. The children had a physical examination and their blood levels of PCBs, DIOXIN, PBDE, and TSH were detected after sample collection. Results In the E‐waste recycling area, the contents of PCBs, PBDE, DIOXIN, and TSH in the blood samples of children were 484.00±84.86 ng·g ‐1 lipid weight, 664.28±262.38 ng·g ‐1 lipid weight, 26.00±19.58 ng·g ‐1 lipid weight and 1.88±0.42 μIU/mL (serum) respectively, while in the control area, the PCBs, PBDE, DIOXIN, and TSH contents were 255.38±95 ng·g ‐1 lipid weight, 375.81±262.43 ng·g ‐1 lipid weight, 39.64±31.86 ng·g ‐1 lipid weight, and 3.31±1.04 μIU/mL respectively. Conclusion The health status of children in the control area are better than that in the contaminated area. Among children who are exposed to persistent organic pollutants, the pollutant content increases significantly in their serum, and the distribution of TSH levels in their bodies are also affected. | HAN GuanGen DING GangQiang LOU XiaoMing WANG XiaoFeng HAN JianLong SHEN HaiTao ZHOU Yu DU LeYan | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 14 | Human ZCCHC12 activates AP-1 and CREB signaling as a transcriptional co-activator显示文摘包含 12 基因(ZCCHC12 ) 的老鼠锌手指 CCHC 领域作为骨头的 transcriptional 激活剂被识别了发信号的形态基因的蛋白质(BMP ) ,和人的 ZCCHC12 被报导与 non-syndromic X 连接智力迟钝(NS-XLMR ) 有关。然而,的细节人的 ZCCHC12 在 NS-XLMR 包含仍然保持不清楚。在这研究,我们在为原子本地化负责的人的 ZCCHC12 蛋白质的中间识别了一个新奇原子本地化信号(NLS ) 。多重织物的北污点分析显示 ZCCHC12 高度在人的大脑被表示。而且,在 situ,杂交证明 ZCCHC12 明确地在老鼠 E10.5 胚胎的前脑,中脑,和间脑区域的 neuroepithelium 被表示。酶记者试金证明 ZCCHC12 作为激活剂提高了使活跃之物蛋白质 1 的 transcriptional 活动(AP-1 ) 和营地反应元素绑定蛋白质(CREB ) 。在结论,我们在 ZCCHC12 识别了新 NLS 并且弄明白 ZCCHC12 作为 AP-1 和 CREB 的 transcriptional 激活剂工作。 | Hong Li Qian Liu Xiang Hu Du Feng Shuanglin Xiang Zhicheng He Xingwang Hu Jianlin Zhou Xiaofeng Ding Chang Zhou Jian Zhang | 2009 | Acta Biochimica et Biophysica Sinica2009，41，7： | 3 |
| 15 | Effect of solution cooling rate on the microstructure and creep deformation mechanism of a rhenium-free second-generation single crystal superalloy显示文摘Various cooling scenarios(water,oil,air and furnace)were employed to study the impacts of the solution cooling rate(SCR)on the microstructure and creep behavior of a novel single-crystal(SX)superalloy.The results showed that the cubic degree and size of theγphases were inversely proportional to the SCR.The creep life first increased and then dropped dramatically with a reduction in the SCR.The creep life of the sample cooled with air cooling(AC)was the highest,up to 144.90 h at 800℃/750 MPa and160.15 h at 1100℃/137 MPa.During creep at 800℃/750 MPa,the improved creep life of the AC sample was mainly attributed to the fine cubicγphases,which decreased the rate ofγ-phase coarsening and favoured plastic deformation by promoting the active movement of dislocations.The AC helped theγphases become rich in Al,Ti and Ta while depleted in Co and Cr,which enhanced its stacking fault energy,thus promoting the formation of dislocation locks.Meanwhile,the largest negative lattice misfit caused by AC induced denserγ/γinterface dislocation networks at 1100℃/137 MPa,which efficiently reduced the minimum creep rate.The calculated average dislocation spacing results indicated that the smallest density of excess dislocations corresponded to the AC sample,proving its greatest creep resistance.Interestingly,the size of the secondaryγphases first decreased and then increased sharply with decreasing SCR during creep at 1100℃/137 MPa,when fine secondaryγphases had a positive role in the blockage of dislocation movement in the matrix.Eventually,the comprehensive SCR effect was explored to provide more guidance in the design of Re-free SX superalloys. | Xipeng Tao Yunling Du Xinguang Wang Jie Meng Yizhou Zhou Jinguo Li Xiaofeng Sun | 2022 | Journal of Materials Science & Technology2022，，36： | 3 |
| 16 | Effect of Cu content on microstructure and properties of Fe-16Cr-2.5Mo damping alloy显示文摘Five Fe-16 Cr-2.5 Mo damping alloys with different Cu contents(0%,0.25%,0.5%,1.0% and 2.0%) were prepared.The microstructure was observed by scanning transmission electron microscopy(STEM) and the damping behavior was measured by using a dynamic mechanical analyzer(DMA).The results show that the grain size of experimental alloy with(0.25–1.0%) Cu was refined compared with the 0 Cu alloy.The Cu element is fully dissolved in the matrix and there are no Cu precipitates and carbides observed.Although the internal stress increases because of Cu addition,the damping capacity of the 0.5 Cu and1.0 Cu alloys has been significantly improved.The reason of damping improvement is that the magnetic domain structure is strongly modified.Meanwhile,the strength was improved gradually due to the Cu solid solution strengthening and grain refining.In the 2.0 Cu alloy,lots of Cu-riched particles appeared in the matrix.These Cu precipitates with 10–15 nm in size are spherical and homogeneously distributed,which strongly induce strength improvement through precipitation strengthening.On the contrary,the elongation and impact energy of the 2.0 Cu alloy decrease sharply.In addition,lots of Cu precipitates will significantly decrease the damping capacity by hindering the mobility of domain walls. | Xiaofeng Hu Yubin Du Desheng Yan Lijian Rong | 2018 | Journal of Materials Science & Technology2018，34，5： | 2 |
| 17 | Prediction of sorghum miRNAs and their targets with computational methods显示文摘microRNAs 是 21-nt 的一个班在 post-transcriptional 起关键作用的长、非编码、最新识别的 RNA 基因规定。他们的目标涉及各种各样的生物过程,包括开发,新陈代谢,和压力反应。尽管很多 miRNAs 在许多种类被报导了,在蜀黍的 miRNAs 的报告是有限的。基于 genomic 调查顺序(GSS ) 和 microRNA (miRNA ) 使用相同搜索第二等的结构, 17 新 miRNAs 的一个总数在这个工作被识别。他们被发现在 11 个 miRNA 家庭之中不均匀的分布式。一些 miRNA 基因在多重地点并且在超过一 genomic 上下文被发现。大多数 miRNAs 在一样的王国以内被保存,但是我们在蜀黍发现 sbi-miR127 和 sbi-miR466 与 H 显示出保存。现代人并且 M。musculus 分别地。经由联机软件 miRU 的那些 17 新 miRNAs 的分析证明他们可能调整 64 目标基因,其大多数涉及 RNA 处理,新陈代谢,房间周期,蛋白质降级,压力反应和交通。11 个 miRNA 家庭中的至少 7 个指向在新陈代谢和压力反应是必要的蛋白质,包括 NADPH 细胞色素 P450 reductase, nucleoside diphosphate kinase 和 superoxide dismutase,建议 miRNAs 起在生物过程的一个必要作用。 | DU JiangFeng WU YongJun FANG XiaoFeng CAO JunXia ZHAO Liang TAO ShiHeng | 2010 | Chinese Science Bulletin2010，55，13： | 2 |
| 18 | Computational prediction and experimental verification of miRNAs in Panicum miliaceum L.显示文摘MicroRNAs (miRNAs) are a class of non-coding RNAs that play critical roles in post-transcriptional regulation. Their target genes are involved in a variety of biological processes such as development, metabolism, and stress response. Panicum miliaceum L. (Panicum) is an important grain crop, but, until now, no miRNAs have been identified in this plant. Using a homology search based on expressed sequence tag (EST) analysis and miRNA precursor secondary structure, a total of 43 new miRNAs were identified. The miRNAs were found to be unevenly distributed among 11 miRNA families. Target analysis using the plant small RNA target analysis server psRNATarget showed that the newly identified miRNAs can potentially regulate 68 target genes. Ten of the 11 miRNA families were annotated as involved in RNA regulation, suggesting they may play an essential role in post-transcriptional regulation in Panicum. Selected miRNAs representing eight of the families were verified by northern blotting, indicating that the prediction method that we used to identify the miRNAs was effective. | WU YongJun DU JiangFeng WANG XiaoLong FANG XiaoFeng SHAN WeiXing LIANG ZongSuo | 2012 | Science China(Life Sciences)2012，55，9： | 2 |
| 19 | M5B3 Boride at the Grain Boundary of a Nickel-based Superalloy显示文摘The grain boundary microstructures of a heat-treated Ni-based cast superalloy IN792 were investigated. The results show that M_5B_3 boride precipitates at the grain boundary. A special orientation relationship between M_5B_3 phase and the matrix at one side of the grain boundary is found. At the same time, two M_5B_3 borides with different orientations could co-exist in a single M_5B_3 particle as an intergrowth besides existing alone, thus forming orientation relationship between the two M_5B_3 phases and matrix. This phenomenon could be attributed to the special orientation relationship between M_5B_3 phase and the matrix. | Beining Du Zhiwu Shi Jinxia Yang Zhaokuang Chu Chuanyong Cui Xiaofeng Sun Liyuan Sheng Yufeng Zheng | 2016 | Journal of Materials Science & Technology2016，32，3： | 2 |
| 20 | Term-Based Pooling in Convolutional Neural Networks for Text Classification显示文摘To achieve good results in convolutional neural networks(CNN) for text classification task, term-based pooling operation in CNNs is proposed. Firstly, the convolution results of several convolution kernels are combined by this method, and then the results after combination are made pooling operation, three sorts of CNN models(we named TBCNN, MCT-CNN and MMCT-CNN respectively) are constructed and then corresponding algorithmic thought are detailed on this basis. Secondly, relevant experiments and analyses are respectively designed to show the effects of three key parameters(convolution kernel, combination kernel number and word embedding) on three kinds of CNN models and to further demonstrate the effect of the models proposed. The experimental results show that compared with the traditional method of text classification in CNNs, term-based pooling method is addressed that not only the availability of the way is proved, but also the performance shows good superiority. | Shuifei Zeng Yan Ma Xiaoyan Zhang Xiaofeng Du | 2020 | China Communications2020，17，4： | 2 |
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