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| 1 | Effects of tumor necrosis factor,endothelin and nitric oxide on hyperdynamic circulation of rats with acute and chronic portal hypertension显示文摘AIM:To evaluate the effect of tumor necrosis factor (TNF),endothelin (ET) and nitric oxide (NO) on hyperdynamic circulation (HC) of rats with acute and chronic portal hypertension (PHT).METHODS: Chronic portal hypertension was induced in Wistar rats by injection of carbon tetrachloride. After two weeks of cirrhosis formation, L-NMMA (25mg/kg) was injected into one group of cirrhotic rats via femoral vein and the experiment was begun immediately. Another group of cirrhotic rats was injected with anti-rat TNFα (300mg/kg) via abdominal cavity twice within 48h and the experiment was performed 24h after the second injection. The blood concentrations of TNFα, ET-1 and NO in portal vein and the nitric oxide synthase (NOS) activity in hepatic tissue were determined pre-and post-injection of anti-rat TNFα or LNMMA. Stroke volume (SV), cardiac output (CO), portal pressure (PP), superior mesenteric artery blood flow (SMA flow) and lilac artery blood flow (IAflow) were measured simultaneously. Acute portal hypertension was established in Wistar rats by partial portal-vein ligation (PVL). The parameters mentioned above were determined at 0.5h,24h, 48h, 72h and 120h after PVL. After the formation of stable PHT, the PVL rats were injected with anti-rat TNFα or L-NMMA according to different groups, the parameters mentioned above were also determined.RESULTS:In cirrhotic rats, the blood levels of TNFα, NO in portal vein and the liver NOS activity were significantly increased (P<0.05) while the blood level of ET-1 was not statistically different (P>0.05) from the control animals(477.67±83.81pg/mL vs 48.87±32.79pg/mL, 278.41±20.11μmol/L vs 113.28±14.51μmol/L, 1.81±0.06μ/mg.prot vs 0.87±0.03μ/mg.prot and 14.33±4.42pg/mL vs8.72±0.79pg/mL, respectively). After injection of anti-rat TNFα,the blood level of TNFα was lower than that in controls (15.17±18.79pg/mL vs 48.87±32.79pg/mL). The blood level of NO and the liver NOS activity were significantly decreased, but still higher than those of the controls. The blood level of ET-1 was not significantly changed. PP,SV,CO, SMAflow and IAflow were ameliorated. After injection of L-NMMA, the blood level of NO and the liver NOS activity were recovered to those of the controls. PP and CO were also recovered to those of the controls. SV, SMAflow and IAflow were ameliorated. In PVL rats, the blood levels of TNFα NO in portal vein and the liver NOS activity were gradually increased and reached the highest levels at 48h after PVL. The blood level of ET-1 among different staged animals was not significantly different from the control animals. PP among different staged animals (2.4±0.18kPa at 0.5h, 1.56±0.08kPa at 24h, 1.74±0.1kPa at 48h,2.38±0.05 kPa at 72h, 2.39±0.16 kPa at 120h) was significantly higher than that in controls (0.9±0.16kPa). After injection of anti-rat TNFα in 72h PVL rats, the blood level of TNFα was lower than that in controls (14±14pg/mL vs 48.87±32.79pg/mL). The blood level of NO and the liver NOS activity were significantly decreased, but still higher than those of the controls. The blood level of ET-1 was not significantly changed. PP was decreased from 2.38±0.05kPa to 1.68±0.12kPa, but significantly higher than that in controls. SV, CO, SMAflow and IAflow were ameliorated.After injection of L-NMMA in 72h PVL rats, the blood level of NO and the liver NOS activity were recovered to those of the controls. PP, SV, CO, SMAflow and IAflow were also recovered to those of the controls.CONCLUSION:NO plays a critical role in the development and maintenance of HC in acute PHT and is a key factor for maintenance of HC in chronic PHT. TNFα may not participate in the hemodynamic changes of HC directly, while play an indirect role by inducing the production of NO through activating NOS. No evidence that circulating ET-1 plays a role in both models of portal hypertension has been found. | Ji-JianWang Gen-WuGao Ren-ZhongGao Chang-AnLiu XiongDing Zhen-XiangYao | 2004 | World Journal of Gastroenterology2004，10，5： | 14 |
| 2 | Research on the conversion relationships between the river and groundwater in the Yellow River drainage area显示文摘Conversion relationships between the river and groundwater in the Yellow River drainage area are studied in this paper based on the geologic and physiognomy conditions and the data of the groundwater regime, isotope, groundwater flow field and field survey. Then eight recharge and discharge modes on the relationships are put forward and the hydraulic characteristics of the modes are analysed, which provides a scientific basis for quantitatively simulating and assessing the conversion relationships, maintenance mechanism of the Yellow River and the regeneration ability of the groundwater in the area. | WANG Wenke KONG Jinling DUAN Lei WANG Yanlin MA Xiongde | 2004 | Science China(Technological Sciences)2004，47，z1： | 5 |
| 3 | A review on investigation of water-preserved coal mining in western China显示文摘Yushenfu mining area is located in an ecological fragile area in western China, the coal seam of which is the Jurassic Ysn'an Foirnalion. The Jurassic Yan'an Formation con tains five minable coal seams, the top layer of which is thick, covered by shallow overburden and located under aquifers. Therefore, the mining induced water flowing fractured zone can easily extend to the aquifers of both the Quaternary Sarahu and Jurassic Zhiluo Formation. This would result in a series of negative hydrological and ecological effects, including groundwater leakage, groundwater lowering, furtherly causing surface vegetation withering and dying, surface water body reduction, spring drying out, and water flow of river being decreased substantially. To solve these environmental problems, several technologies have been carried out by Chinese scientists, one of which is water-preserved coal mining. This paper presents a review of the origin, definition and development of water-preserved coal mining, and its applications in Yushenfu mining area. The applicable conditions, research contents, research methodology, and technical foundation of water-preserved coal mining are addressed in this paper. The future research focuses regarding water-preserved coal mining in China are also discussed in this paper. Its results serve as a guide for selecting the methods to be preferred for mining in case the geological conditions, roof overburden structure and coal mining process are similar to Yushenfu mining area. | Limin Fan Xiongde Ma | 2018 | International Journal of Coal Science & Technology2018，5，4： | 2 |
| 4 | Effect of Agand CeO2 on Friction and Wear Properties of Ni-base Composite at High Temperature显示文摘 | LIJ XIONGD HUANGZ | 2009 | Wear2009，267，： | 1 |
| 5 | Effect of surface laser texture on friction properties of nickelbased composite 显示文摘 | LIJL XIONGDS DAIJ H etal | 2010 | Tribology International2010，43，56： | 1 |
| 6 | 土地利用方式对黄河漫滩土壤微生物群落结构和多样性的影响显示文摘土壤微生物群落及其多样性是土壤碳和养分循环的重要生物指标。土地利用变化是影响漫滩生态系统土壤微生物群落组成的主要决定因素。然而,土壤微生物群落的结构和多样性如何响应土地利用变化,以及这些变化的主要驱动因素是什么,仍不清楚。本研究在黄河漫滩进行,以检验土地利用变化对土壤微生物群落的影响。选取了4种土地利用类型(灌丛、农田、草地和森林),其中以灌木地为对照,用磷脂脂肪酸测量了土壤微生物组成和多样性。研究结果表明,土地利用变化显著影响了总细菌、真菌和革兰氏阳性/阴性细菌。与灌丛相比,农田的总磷脂脂肪酸和细菌较高,森林的真菌较高。土壤pH值和全磷是微生物组成的最佳预测因子,分别解释了37%和26%的变异性。土壤全氮和硝态氮是影响微生物多样性的主要因素。花生农田的土壤碳含量、土壤碳储量、磷脂脂肪酸总量和微生物多样性最高,表明漫滩具有巨大的碳汇潜力。这些研究结果表明,黄河漫滩的农田对于维持土壤微生物群落和土壤碳固存至关重要。 | Xiongde Dong Leyun Yang Laura Sofie Harbo Xinyu Yan Ji Chen Cancan Zhao Yutong Xiao Hao Liu Shilin Wang Yuan Miao Dong Wang Shijie Han | 2023 | Journal of Plant Ecology2023，16，1： | 0 |
| 7 | Comparative analysis of plastomes in Oxalidaceae:Phylogenetic relationships and potential molecular markers显示文摘The wood sorrel family,Oxalidaceae,is mainly composed of annual or perennial herbs,a few shrubs,and trees distributed from temperate to tropical zones.Members of Oxalidaceae are of high medicinal,ornamental,and economic value.Despite the rich diversity and value of Oxalidaceae,few molecular markers or plastomes are available for phylogenetic analysis of the family.Here,we reported four new whole plastomes of Oxalidaceae and compared them with plastomes of three species in the family,as well as the plastome of Rourea microphylla in the closely related family Connaraceae.The eight plastomes ranged in length from 150,673 bp(Biophytum sensitivum)to 156,609 bp(R.microphylla).Genome annotations revealed a total of 129e131 genes,including 83e84 protein-coding genes,eight rRNA genes,37 tRNA genes,and two to three pseudogenes.Comparative analyses showed that the plastomes of these species have minor variations at the gene level.The smaller plastomes of herbs B.sensitivum and three Oxalis species are associated with variations in IR region sizes,intergenic region variation,and gene or intron loss.We identified sequences with high variation that may serve as molecular markers in taxonomic studies of Oxalidaceae.The phylogenetic trees of selected superrosid representatives based on 76 protein-coding genes corroborated the Oxalidaceae position in Oxalidales and supported it as a sister to Connaraceae.Our research also supported the monophyly of the COM(Celastrales,Oxalidales,and Malpighiales)clade. | Xiaoping Li Yamei Zhao Xiongde Tu Chengru Li Yating Zhu Hui Zhong Zhong-Jian Liu Shasha Wu Junwen Zhai | 2021 | Plant Diversity2021，43，4： | 0 |
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