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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Evolving concepts in bone infection: redefining “biofilm”,“acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy”显示文摘Osteomyelitis is a devastating disease caused by microbial infection of bone. While the frequency of infection following elective orthopedic surgery is low, rates of reinfection are disturbingly high. Staphylococcus aureus is responsible for the majority of chronic osteomyelitis cases and is often considered to be incurable due to bacterial persistence deep within bone. Unfortunately, there is no consensus on clinical classifications of osteomyelitis and the ensuing treatment algorithm. Given the high patient morbidity,mortality, and economic burden caused by osteomyelitis, it is important to elucidate mechanisms of bone infection to inform novel strategies for prevention and curative treatment. Recent discoveries in this field have identified three distinct reservoirs of bacterial biofilm including: Staphylococcal abscess communities in the local soft tissue and bone marrow, glycocalyx formation on implant hardware and necrotic tissue, and colonization of the osteocyte-lacuno canalicular network(OLCN) of cortical bone. In contrast, S.aureus intracellular persistence in bone cells has not been substantiated in vivo, which challenges this mode of chronic osteomyelitis. There have also been major advances in our understanding of the immune proteome against S. aureus, from clinical studies of serum antibodies and media enriched for newly synthesized antibodies(MENSA), which may provide new opportunities for osteomyelitis diagnosis, prognosis, and vaccine development. Finally, novel therapies such as antimicrobial implant coatings and antibiotic impregnated 3D-printed scaffolds represent promising strategies for preventing and managing this devastating disease. Here, we review these recent advances and highlight translational opportunities towards a cure. | Elysia A. Masters Ryan P. Trombetta Karen L. de Mesy Bentley Brendan F Boyce Ann Lindley Gill Steven R. Gill Kohei Nishitani Masahiro Ishikawa Yugo Morita Hiromu Ito Sheila N. Bello-Irizarry Mark Ninomiya James D. Brodell Jr. Charles C. Lee Stephanie P. Hao Irvin Oh Chao Xie Hani A. Awad John L. Daiss John R. Owen Stephen L. Kates Edward M. Schwarz Gowrishankar Muthukrishnan | 2019 | Bone Research2019，7，3： | 19 |
| 3 | Optimizing Parameters of CSM-CERES-Maize Model to Improve Simulation Performance of Maize Growth and Nitrogen Uptake in Northeast China显示文摘Crop models can be useful tools for optimizing fertilizer management for a targeted crop yield while minimizing nutrient losses.In this paper,the parameters of the decision support system for agrotechnology transfer(DSSAT)-CERES-Maize were optimized using a new method to provide a better simulation of maize(Zea mays L.) growth and N uptake in response to different nitrogen application rates.Field data were collected from a 5 yr field experiment(2006-2010) on a Black soil(Typic hapludoll) in Gongzhuling,Jilin Province,Northeast China.After cultivar calibration,the CERES-Maize model was able to simulate aboveground biomass and crop yield of in the evaluation data set(n-RMSE=5.0-14.6%),but the model still over-estimated aboveground N uptake(i.e.,with E values from-4.4 to-21.3 kg N ha-1).By analyzing DSSAT equation,N stress coefficient for changes in concentration with growth stage(CTCNP2) is related to N uptake.Further sensitivity analysis of the CTCNP2 showed that the DSSAT model simulated maize nitrogen uptake more precisely after the CTCNP2 coefficient was adjusted to the field site condition.The results indicated that in addition to calibrating 6 coefficients of maize cultivars,radiation use efficiency(RUE),growing degree days for emergence(GDDE),N stress coefficient,CTCNP2,and soil fertility factor(SLPF) also need to be calibrated in order to simulate aboveground biomass,yield and N uptake correctly.Independent validation was conducted using 2008-2010 experiments and the good agreement between the simulated and the measured results indicates that the DSSAT CERES-Maize model could be a useful tool for predicting maize production in Northeast China. | LIU Hai-long YANG Jing-yi HE Ping BAI You-lu JIN Ji-yun Craig F Drury ZHU Ye-ping YANGXue-ming LI Wen-juan XIE Jia-gui YANG Jing-min Gerrit Hoogenboom | 2012 | Journal of Integrative Agriculture2012，11，11： | 13 |
| 4 | Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes显示文摘 | Lou JD Xie F Zhang WW | 2001 | British J Pharmacol2001，132，1： | 2 |
| 5 | Secondary structural formation of alpha-synuclein amyloids as revealed by g-factor of solid-state circular dichroism.显示文摘 | Lin XJ Zhang F Xie YY Bao WJ He JH Hu HY | 2006 | 中国生物学文摘2006，20，9： | 2 |
| 6 | COI1:An Arabidopsis gene required for jasmonate-regulated defense and fertility显示文摘 | Xie D X Feys B F James S | 1998 | Science1998，280，： | 2 |
| 7 | On Congruence on Ordered Semigroups 显示文摘 | Xie X Y Wa M F | 1997 | Math Japorica1997，45，： | 2 |
| 8 | STATISTICALLY FRACTAL STRENGTH THEORY FOR BRITTLE MATERIALS显示文摘Based on the hypothesis of the fractal distribution of crack sizes in brittle materials andthe weakest link principle,the relationship between the fractal dimension of the size-frequency distri-bution of cracks and the Weibull Modulus is derived,which reveals the geometrical nature of theWeibull Modulus.The influences of the size distribution and the orientation distribution of cracks aswell as the irregularity of the crack propagation on the strength are all taken into account.Finally,ageneral expression for the statistical strength of brittle materials in complex tensile stress state is ob-tained. | Gao, F Xie, HP | 1996 | Acta Mechanica Solida Sinica1996，9，1： | 2 |
| 9 | The Multi-staged Formation Process of Titanium Oxide Nanotubes and its Thermal Stability 显示文摘 | Li W Fu T Xie F | 2007 | Materials Letters2007，61，： | 1 |
| 10 | RTE1 is a Golgi-assoeiated and ETR1 -dependent negative regulator of ethylene responses 显示文摘 | Zhou X Liu Q Xie F | 2007 | Plant Physiol2007，145，1： | 1 |
| 11 | 2-Aminopyrimidine-4,6-diol as an efficient ligand for solvent-free copper-catalyzed N-arylations of imidazoles with aryl and heteroaryl halides显示文摘 | XIE Y X PI S F WANG J | 2006 | J Org Chem2006，71，： | 1 |
| 12 | Volatile flavor constituents in roasted pork of mini-pig显示文摘 | XIE J C SUN B G ZHENG F P | 2008 | Food Chemistry2008，109，： | 1 |
| 13 | Interaction of white spot syndrome virus VP26 protein with actin显示文摘 | Xie X X Yang F | 2005 | Virology2005，336，： | 1 |
| 14 | Temperature-compen- sating multiple fiber bragg grating strain sensors with a metrological grating显示文摘 | Xie F Zhang S L Li Y | 2004 | Optics and Lasers in Engi- neering2004，41，1： | 1 |
| 15 | Correlation betw een myopia and major biometric parameters of the eye:a retrospective clinical study显示文摘 | Xie R Zhou XT Lu F Chen M Xue A Chen S | 2009 | Optom Vis Sci2009，86，5： | 1 |
| 16 | Agency problems at dual- class companies 显示文摘 | Masulis R W Wang C Xie F | 2009 | Journal of Finance2009，64，4： | 1 |
| 17 | Complete Genome Sequence of Lymphocystis Disease Virus (LCDV-C) Isolated from China显示文摘 | Zhang Q Y xiao F Xie J | 2004 | J Virol2004，78，： | 1 |
| 18 | 2D FEM Estimate of Tool Wear in Turning Operation显示文摘 | L-J Xie J Schmidt C Schmidt F Biesinger | 2005 | Wear2005，258，： | 1 |
| 19 | A 35 GHz low-voltage third-harmonic gyrotron with a permanent magnet system显示文摘 | Li H F Xie Z L Wang W X | 2003 | IEEE Trans on Plasma Sci2003，31，2： | 1 |
| 20 | A survey of mobility management in next-generation ali-IP-based wireless systems显示文摘 | AKYILDIZ I F XIE J MOHANTY S | 2004 | IEEE Wireless Communications2004，4，11： | 1 |
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