|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevalence of Autism Spectrum Disorder in China:A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years显示文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children. | Hao Zhou Xiu Xu Weili Yan Xiaobing Zou Lijie Wu Xuerong Luo Tingyu Li Yi Huang Hongyan Guan Xiang Chen Meng Mao Kun Xia Lan Zhang Erzhen Li Xiaoling Ge Lili Zhang Chunpei Li Xudong Zhang Yuanfeng Zhou Ding Ding Andy Shih Eric Fombonne Yi Zheng Jisheng Han Zhongsheng Sun Yong-hui Jiang Yi Wang LATENT-NHC Study Team | 2020 | Neuroscience Bulletin2020，36，9： | 158 |
| 2 | Analysis of status and countermeasures of cancer incidence and mortality in China显示文摘Cancer is the leading cause of human deaths in the world and produces serious economic burdens. On September 12, 2018, the academic journal A Cancer Journal for Clinicians published an article about the latest statistics of cancers worldwide, which provided a status report on the global burden of 36 cancers in 185 countries worldwide. Cancer has also become a serious public health problem in China and caused more and more attention of the government and people in recent years. This review analyzes the incidence, mortality and prevalent trend of cancers in China, discusses the reasons behind this status, and reviews the potential countermeasures for cancer prevention and control in China. | Chunchun Wu Mengna Li Hanbing Meng Yukun Liu Weihong Niu Yao Zhou Ran Zhao Yumei Duan Zhaoyang Zeng Xiaoling Li Guiyuan Li Wei Xiong Ming Zhou | 2019 | Science China(Life Sciences)2019，62，5： | 175 |
| 3 | Adaptive block dynamic surface control for integrated missile guidance and autopilot显示文摘A novel integrated guidance and autopilot design method is proposed for homing missiles based on the adaptive block dynamic surface control approach. The fully integrated guidance and autopilot model is established by combining the nonlinear missile dynamics with the nonlinear dynamics describing the pursuit situation of a missile and a target in the three-dimensional space. The integrated guidance and autopilot design problem is further converted to a state regulation problem of a time-varying nonlinear system with matched and unmatched uncertainties. A new and simple adaptive block dynamic surface control algorithm is proposed to address such a state regulation problem. The stability of the closed-loop system is proven based on the Lyapunov theory. The six degrees of freedom (6DOF) nonlinear numerical simulation results show that the proposed integrated guidance and autopilot algorithm can ensure the accuracy of target interception and the robust stability of the closed-loop system with respect to the uncertainties in the missile dynamics. | Hou Mingzhe Liang Xiaoling Duan Guangren | 2013 | Chinese Journal of Aeronautics2013，26，3： | 56 |
| 4 | Trends of foodborne diseases in China: lessons from laboratory- based surveillance since 2011显示文摘Foodborne 疾病是世界范围的最重要的公共健康问题之一。中国在食物链的所有方面面对各种各样、崭新的挑战。从从 2013 ~ 2016 的基于实验室的 foodborne 疾病监视系统的数据,以及不同区域和年龄,能在与多样的特征检测的病原体的模式与差别一起被发现。Vibrio parahaemolyticus 是在中国的传染腹泻的领先的原因,特别在在沿海的区域的成年人之中。沙门氏菌是为实质的社会经济的负担负责的严肃、广泛地分布式的病原体。Shigella 主要在 5 年下面在孩子之中与开发更少的区域在西北中国和内陆省(河南省) 被识别。从从 2011 ~ 2016 报导系统的 foodborne 疾病爆发的数据证明有毒的动物和为大多数死亡负责的植物因素在在西南区域的遥远的区域是有毒的蘑菇(54.7%) 。引起了报导的大多数案例(42.3%) 的生物危险被归因于 V。parahaemolyticus, foodborne 爆发的领先的原因。在这评论,我们在中国总结最近的监视途径到 foodborne 疾病并且在发达国家把结果与那些作比较。 | Jikai Liu Li Bai Weiwei Li Haihong Han Ping Fu Xiaochen Ma Zhenwang Bi Xiaorong Yang Xiuli Zhang Shiqi Zhen Xiaoling Deng Xiumei Liu Yunchang Guo | 2018 | Frontiers of Medicine2018，12，1： | 55 |
| 5 | Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients显示文摘Pathogenic human coronavirus infections,such as severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERS-CoV),cause high morbidity and mortality[1,2].Recently,a severe pneumonia-associated respiratory syndrome caused by a new coronavirus(SARS-CoV-2)was reported in December 2019 in the city of Wuhan,Hubei province,China[3-5],which was also named as pneumonia-associated respiratory syndrome(PARS)[6]and can cause coronavirus disease 2019(COVID-19)to seriously endanger human health. | Yonggang Zhou Binqing Fu Xiaohu Zheng Dongsheng Wang Changcheng Zhao Yingjie Qi Rui Sun Zhigang Tian Xiaoling Xu Haiming Wei | 2020 | National Science Review2020，7，6： | 54 |
| 6 | Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways显示文摘Acute lung injury(ALI) or acute respiratory distress syndrome(ARDS) is a severe, lifethreatening medical condition characterized by widespread inflammation in the lungs, and is a significant source of morbidity and mortality in the patient population. New therapies for the treatment of ALI are desperately needed. In the present study, we examined the effect of andrographolide sulfonate, a water-soluble form of andrographolide(trade name: Xi-Yan-Ping Injection), on lipopolysaccharide(LPS)-induced ALI and inflammation. Andrographolide sulfonate was administered by intraperitoneal injection to mice with LPS-induced ALI. LPS-induced airway inflammatory cell recruitment and lung histological alterations were significantly ameliorated by andrographolide sulfonate. Protein levels of pro-inflammatory cytokines in bronchoalveolar lavage fluid(BALF) and serum were reduced by andrographolide sulfonate administration. m RNA levels of pro-inflammatory cytokines in lung tissue were also suppressed. Moreover, andrographolide sulfonate markedly suppressed the activation of mitogen-activated protein kinase(MAPK) as well as p65 subunit of nuclear factor-κB(NF-κB). In summary, these results suggest that andrographolide sulfonate ameliorated LPS-induced ALI in mice by inhibiting NF-κB and MAPK-mediated inflammatory responses. Our study shows that water-soluble andrographolide sulfonate may represent a new therapeutic approach for treating inflammatory lung disorders. | Shuang Peng Nan Hang Wen Liu Wenjie Guo Chunhong Jiang Xiaoling Yang Qiang Xu Yang Sun | 2016 | Acta Pharmaceutica Sinica B2016，6，3： | 38 |
| 7 | Hygroscopic growth of aerosol scattering coefficient:A comparative analysis between urban and suburban sites at winter in Beijing显示文摘A humidity controlled inlet system was developed to measure the hygroscopic growth of aerosol scattering coefficient in conjunction with nephelometry at an urban site of Chinese Academy of Meteorological Sciences (CAMS) in Beijing and a rural site at Shangdianzi Regional Background Air Pollution Monitoring Station (SDZ) outside Beijing during winter, from December 2005 to January 2006. Measurements were carried out at a wavelength of 525 nm with an Ecotech M9003 nephelometer. The hygroscopic growth function (or factor) of the aerosol scattering coefficient f(RH) increased continuously with increasing relative humidity (RH) and showed no obvious 'step-like' deliquescent behavior at both sites during the experiment. The average growth factor f(RH) at the SDZ site could reach 1.5 when RH increased from less than 40% to 92%, and to 2.1 at the CAMS site when RH increased from less than 40% to 93%. The average hygroscopic growth factor at a relative humidity of 80%, f(RH = 80 ± 1%), was found to be about 1.26 ± 0.15 at CAMS and 1.24 ± 0.11 at SDZ. Further analysis indicated that under relatively polluted conditions, the average hygroscopic growth factor was higher at the CAMS site than that at the SDZ site. However, under relatively clean air conditions, the difference between the two sites was small, showing a hygroscopic growth behavior similar to those of burning biomass or blowing dust. These results reflected the different characteristics of aerosol types at the two sites. | Peng Yan Xiaole Pan Jie Tang Xiuji Zhou Renjian Zhang Limin Zeng | 2009 | Particuology2009，7，1： | 30 |
| 8 | Differences in lithospheric structures between two sides of Taihang Mountain obtained from the Zhucheng-Yichuan deep seismic sounding profile显示文摘A 2-D model of lithospheric velocity structures in the southern part of the North China Craton was obtained using data from the Zhucheng-Yichuan deep seismic sounding profile.Results show that there are great differences in lithospheric structures between two sides of Taihang Mountain.In the eastern region,the lithosphere is thinner,with a thickness of about 70-80 km,while in the western region,the thickness is 85-120 km.There is a jump of the lithospheric thickness across Taihang Mountain gravity anomaly belt with a magnitude of about 30 km.P wave velocities of the lithospheric mantle and lower crust are lower in the eastern region and higher in the western region.In the eastern region,there are low velocity bodies in the middle and lower crust,while none were found in the western region.These differences indicate that the Taihang Mountain gravity anomaly belt is a belt with a abrupt change of lithospheric thickness and lithological composition.According to the Pm waveform,it can be deduced that the Moho in the eastern region is not a sharp discontinuity,but a complex transitional zone.From a preliminary analysis,it is found that the geothermal mechanical-chemical erosion could be the main mechanism causing the thinning and destruction of the lithosphere beneath the eastern side of Taihang Mountain.In addition,subduction of the Pacific Plate is an important factor which changes the properties of the lithospheric mantle of the North China Craton. | LI SongLin LAI XiaoLing LIU BaoFeng WANG ZhiSuo HE JiaYong SUN Yi | 2011 | Science China Earth Sciences2011，54，6： | 27 |
| 9 | Tracking shallow marine red beds through geological time as exemplified by the lower Telychian (Silurian) in the Upper Yangtze Region,South China显示文摘Marine red beds occur frequently in China through geological time.Despite their complex environments,the red beds are found in three depositional settings:1) oceanic,deep water,as in the Upper Cretaceous of southern Tibet;2) outer shelf,deeper water,as in the Lower-Middle Ordovician of South China;and 3) inner shelf,shallow water,as in the Silurian and Triassic in South China.The Silurian marine red beds are recurrent in the lower Telychian,upper Telychian,and upper Ludlow.This paper is to document the marine nature of the lower Telychian red beds (LRBs) in the Upper Yangtze Region and to discuss the spatial and temporal distribution of the LRBs and their depositional environments.The LRBs are best developed on the north side of the Cathaysian Oldland,which can be interpreted as the source area.It is inferred that they were deposited during a marine regression,characterized by the lack of upwelling,low nutrition and organic productivity with a decrease of biodiversity and a high rate of sedimentation.The iron-rich sediments may have been transported by rivers on the oldland into the Upper Yangtze Sea,as rates of deposition were rapid enough to counteract normal reducing effect around sediment-water interface.The LRBs are different from the off-shore,deeper water red beds of lower Telychian in Avalonia and Baltica and further from the oceanic,deep water red beds of Upper Cretaceous in southern Tibet chiefly in palaeogeographic settings,biotic assemblages and marine environments. | RONG JiaYu WANG Yi ZHANG XiaoLe | 2012 | Science China Earth Sciences2012，55，5： | 25 |
| 10 | Three-dimensional hydrodynamic and water quality model for TMDL development of Lake Fuxian,China显示文摘Lake Fuxian is the largest deep freshwater lake in China.Although its average water quality meets Class I of the China National Water Quality Standard(CNWQS),i.e.,GB3838-2002,monitoring data indicate that the water quality approaches the Class II threshold in some areas.Thus it is urgent to reduce the watershed load through the total maximum daily load(TMDL) program.A three-dimensional hydrodynamic and water quality model was developed for Lake Fuxian,simulating flow circulation and pollutant fate and transport.The model development process consists of several steps,including grid generation,initial and boundary condition configurations,and model calibration processes.The model accurately reproduced the observed water surface elevation,spatiotemporal variations in temperature,and total nitrogen(TN),total phosphorus(TP),and chemical oxygen demand(COD) concentrations,suggesting a reasonable numerical representation of the prototype system for further TMDL analyses.The TMDL was calculated using two interpretations of the water quality standards for Class I of the CNWQS based on the maximum instantaneous surface and annual average surface water concentrations.Analysis of the first scenario indicated that the TN,TP and COD loads should be reduced by 66%,68% and 57%,respectively.Water quality was the highest priority;however,local economic development and cost feasibility for load reduction can pose significant issues.In the second interpretation,the model results showed that,under the existing conditions,the average water quality meets the Class I standard and therefore load reduction is unnecessary.Future studies are needed to conduct risk and cost assessments for realistic decision-making. | Lei Zhao Xiaoling Zhang Yong Liu Bin He Xiang Zhu Rui Zou Yuanguan Zhu | 2012 | Journal of Environmental Sciences2012，24，8： | 25 |
| 11 | Homocysteine-mediated cholesterol efflux via ABCA1 and ACAT1 DNA methylation in THP-1 monocyte-derived foam cells显示文摘Homocysteine (Hcy ) 为心血管的事件作为一个流行风险因素被认出了。装载胆固醇的泡沫房间是动脉粥样硬化患者损害的一个中央部件。ATP 有约束力的盒子 transporter A1 (ABCA1 ) 它调停细胞的胆固醇和 phospholipids 的流出,是在类脂化合物的限制率的步新陈代谢。酰辅酶 A:cholesterol acyltransferase-1 (ACAT1 ) 在巨噬细胞支持胆固醇酉旨的累积,从而导致泡沫房间形成,在动脉粥样硬化的早舞台的一个特点。在这研究,有教养的导出单核白血球的泡沫房间为 24 h 与 Hcy 的临床的相关集中被孵化。胆固醇的房间和累积被发现的泡沫的两个都增加的数字,和 ABCA1 的 mRNA 和蛋白质表示层次被减少,当 ACAT1 表示面对 Hcy 被增加时。而且,而 ACAT1 DNA methylation 被使用 Hcy 的不同集中减少, ABCA1 基因的 DNA methylation 水平被增加。而且,我们的结果显示出那项 DNA methyltransferase (DNMT ) 活动和 DNA methyltransferase 1 (DNMT1 ) mRNA 表示被 Hcy 增加。DNA methylation 有功能经由 DNMT 调整 ABCA1 和 ACAT1 的表示,这被显示。在结论,这些结果建议 Hcy 导致的 ABCA1 和 ACAT1 DNA methylation 可以在导出单核白血球的泡沫房间在 ABCA1 和 ACAT1 表示和胆固醇的累积起一个潜在的作用。 | Yu Liang Xiaoling Yang Linna Ma Xin Cai Lei Wang Cheng Yang Guizhong Li Minghao Zhang Weiwei Sun Yideng Jiang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，3： | 26 |
| 12 | Neuronal apoptosis in cerebral ischemia/reperfusion area following electrical stimulation of fastigial nucleus显示文摘Previous studies have indicated that electrical stimulation of the cerebellar fastigial nucleus in rats may reduce brain infarct size, increase the expression of Ku70 in cerebral ischemia/ reperfusion area, and decrease the number of apoptotic neurons. However, the anti-apoptotic mechanism of Ku70 remains unclear. In this study, fastigial nucleus stimulation was given to rats 24, 48, and 72 hours before cerebral ischemia/reperfusion injury. Results from the electrical stimulation group revealed that rats exhibited a reduction in brain infarct size, a significant increase in the expression of Ku70 in cerebral ischemia/reperfusion regions, and a decreased number of terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)-positive cells. Double immunofluorescence staining revealed no co-localization of Ku70 with TUNEL-positive cells. However, Ku70 partly co-localized with Bax protein in the cytoplasm of rats with cerebral ischemia/reperfusion injury. These findings suggest an involvement of Ku70 with Bax in the cytoplasm of rats exposed to electrical stimulation of the cerebellar fastigial nucleus, and may thus provide an understanding into the anti-apoptotic activity of Ku70 in cerebral ischemia/reperfusion injury. | Jingli Liu Jinpin Li Yi Yang Xiaoling Wang Zhaoxia Zhang Lei Zhang | 2014 | Neural Regeneration Research2014，9，7： | 26 |
| 13 | Long non-coding RNAs in cancer显示文摘Long non-coding RNAs (lncRNAs) are a group of RNA transcripts that exceed 200 nt in length, yet lack significant open reading frames (ORFs) [1–4]. In contrast | GONG ZhaoJian ZHANG ShanShan ZHANG WenLing HUANG HongBin LI Qiao DENG Hao MA Jian ZHOU Ming XIANG Juan Juan WU MingHua LI XiaYu XIONG Wei LI XiaoLing LI Yong ZENG ZhaoYang LI GuiYuan | 2012 | Science China(Life Sciences)2012，55，12： | 22 |
| 14 | SIRT1 and energy metabolism显示文摘Sirtuin 1 (SIRT1 ) 是在各种各样的新陈代谢的纸巾作为一个关键新陈代谢的传感器出现了的大多数保存哺乳动物的 NAD+ 依赖的蛋白质 deacetylase。响应不同环境刺激, SIRT1 直接连接细胞的新陈代谢的地位到染色质结构和基因表示的规定,从而 modulating 许多细胞的过程象精力那样新陈代谢和压力反应。最近的研究证明了 SIRT1 在肝控制葡萄糖和类脂化合物新陈代谢,支持胖动员并且刺激在白脂肪质的组织的白脂肪改变的褐,在胰的控制胰岛素分泌物,在视下丘的感觉营养素可获得性,在巨噬细胞影响导致肥胖的发炎,并且在新陈代谢的纸巾调制生理节奏的钟的活动。这评论在在不同新陈代谢的纸巾调整精力新陈代谢集中于 SIRT1 的角色。 | Xiaoling Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，1： | 23 |
| 15 | Vitamin D receptor and its protective role in diabetic nephropathy显示文摘 | Guan Xiaoling Yang Huajie Zhang Wei Wang Huanjun Liao Lin | 2014 | Chinese Medical Journal2014，，2： | 22 |
| 16 | Changes of protein oxidation,lipid oxidation and lipolysis in Chinese dry sausage with different sodium chloride curing salt content显示文摘The effect of sodium chloride(NaCl)curing salt content on protein oxidation,lipid oxidation and lipolysis of Chinese dry sausage was investigated.Two groups Chinese dry sausages with 2%and 4%(m/m)salt content were studied.The degree of protein oxidation increased during the processes in two groups sausages,while the content of phospholipids decreased,neutral lipids and free fatty acids increased.The degree of protein oxidation,lipid oxidation and lipolysis in 4%NaCl content group was higher than those in 2%NaCl content group,while 4%NaCl content group has higher lipase activity.In conclusion,4%NaCl may facilitate the protein oxidation,lipid hydrolysis and oxidation in Chinese dry sausage,and the protein oxidation had strong correlation with lipid oxidation and lipolysis.The results could provide a basis for improving the technology of industrial production. | Bing Zhao Huimin Zhou Shunliang Zhang Xiaoqian Pan Su Li Ning Zhu Qianrong Wu Shouwei Wang Xiaoling Qiao Wenhua Chen | 2020 | Food Science and Human Wellness2020，9，4： | 22 |
| 17 | Time-dependent categorization of volatile aroma compound formation in stewed Chinese spicy beef using electron nose profile coupled with thermal desorption GC–MS detection显示文摘In the present study,flavor profiles of Chinese spiced beef in the cooking process were comparatively analyzed by electronic nose,gas chromatography–mass spectrometry(GC–MS)with a thermal desorption system(TDS),and solid-phase microextraction(SPME).A total of 82 volatile compounds were identified,and 3-methyl-butanal,pentanal,hexanal,-xylene,heptanal,limonene,terpinene,octanal,linalool,4-terpinenol,-terpineol,and(E)-anethole were identified as the characteristic flavor compounds in Chinese spiced beef.Variation in the content of volatile components produced by different cooking processes was observed.In general,a cooking time of 4 h resulted in optimal flavor quality and stability.Results indicated that the electronic nose could profile and rapidly distinguish variation among different cooking time.The volatile profiling by TDS-GC–MS and responses from the electronic nose,in combination with multivariate statistical analysis,are a promising tool for control the cooking process of spiced beef. | Hui Gong Zhen Yang Meng Liu Zhijia Shi Jiapeng Li Wenhua Chen Xiaoling Qiao | 2017 | Food Science and Human Wellness2017，6，3： | 21 |
| 18 | CMIP6 Evaluation and Projection of Temperature and Precipitation over China显示文摘This article evaluates the performance of 20 Coupled Model Intercomparison Project phase 6(CMIP6)models in simulating temperature and precipitation over China through comparisons with gridded observation data for the period of 1995–2014,with a focus on spatial patterns and interannual variability.The evaluations show that the CMIP6 models perform well in reproducing the climatological spatial distribution of temperature and precipitation,with better performance for temperature than for precipitation.Their interannual variability can also be reasonably captured by most models,however,poor performance is noted regarding the interannual variability of winter precipitation.Based on the comprehensive performance for the above two factors,the“highest-ranked”models are selected as an ensemble(BMME).The BMME outperforms the ensemble of all models(AMME)in simulating annual and winter temperature and precipitation,particularly for those subregions with complex terrain but it shows little improvement for summer temperature and precipitation.The AMME and BMME projections indicate annual increases for both temperature and precipitation across China by the end of the 21st century,with larger increases under the scenario of the Shared Socioeconomic Pathway 5/Representative Concentration Pathway 8.5(SSP585)than under scenario of the Shared Socioeconomic Pathway 2/Representative Concentration Pathway 4.5(SSP245).The greatest increases of annual temperature are projected for higher latitudes and higher elevations and the largest percentage-based increases in annual precipitation are projected to occur in northern and western China,especially under SSP585.However,the BMME,which generally performs better in these regions,projects lower changes in annual temperature and larger variations in annual precipitation when compared to the AMME projections. | Xiaoling YANG Botao ZHOU Ying XU Zhenyu HAN | 2021 | Advances in Atmospheric Sciences2021，38，5： | 21 |
| 19 | The fate of medications evaluated for ischemic stroke pharmacotherapy over the period 1995–2015显示文摘Stroke is a brain damage caused by a loss of blood supply to a portion of the brain, which requires prompt and effective treatment. The current pharmacotherapy for ischemic stroke primarily relies on thrombolysis using recombinant tissue plasminogen activators(rt-PAs) to breakdown blood clots. Neuroprotective agents that inhibit excitatory neurotransmitters are also used to treat ischemic stroke but have failed to translate into clinical benefits. This poses a major challenge in biomedical research to understand what causes the progressive brain cell death after stroke and how to develop an effective pharmacotherapy for stroke. This brief review analyzes the fate of about 430 potentially useful stroke medications over the period 1995–2015and describes in detail those that successfully reached the market. Hopefully, the information from this analysis will shed light on how future stroke research can improve stroke drug discovery. | Xiaoling Chen Kewei Wang | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 18 |
| 20 | Younger age of onset and multiple primary lesions associated with esophageal squamous cell carcinoma cases with a positive family history of the cancer suggests genetic predisposition显示文摘 | Jia Nan Wen Xiaoduo Zhang Nan YangYi Zhang Liwei Wang Xiaoling Wang Na Wen Denggui | 2014 | Chinese Medical Journal2014，，15： | 16 |
您所在的机构暂未开通此部分的功能，请联系管理员