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	题名	作者	年代	出处	被引量
1	Anti-encystment and amoebicidal activity of Lonicera japonica Thunb. and its major constituent Chlorogenic acid in vitro显示文摘Objective:To examine the acanthamoebicidal effects of ethyl acetate,aqueous and butanol fractions of dried flower buds of Lonicera japonica(L.japonica) Thunb.(Flos Lonicerae) in vitro.Methods:Acanthamoeba triangularis isolates were obtained from environmental water samples and identified by PCR.They were exposed to ethyl acetate,water and butanol fractions of L.japonica Thunb.at concentrations ranging from 0.5 mg/m L to 1.5 mg/m L.The extracts were evaluated for growth inhibition at 24,48 and 72 h,respectively.Chlorogenic acid at a concentration of 1 mg/mL was examined for inhibition of encystment.Results:Ethyl acetate fraction at a concentration of 1.5 mg/mL evoked a significant reduction of trophozoite viability by 48.9% after 24 h,49.2% after 48 h and 33.7% after 72 h Chlorogenic acid,the major active constituent of L.japonica Thunb.at the concentration of 1 mg/mL reduced the cysts/trophozoite ratio by 100% after 24 h,84.0% after 48 h and 72.3% after 72 h.This phenolic compound at concentration of 1 mg/mL concurrent with 0.6% hydrogen peroxide inhibited hydrogen peroxide-induced encystment by 92.8% at 72 h.Conclusions:Results obtained from this study show that ethyl acetate fraction at 1.5 mg/m L is the most potent fraction of L.japonica Thunb.and its major constituent chlorogenic acid showed the remarkable inhibition of encystment at a concentration of 1 mg/mL.	Tooba Mahboob Abdul-Majid Azlan Tian-Chye Tan Chandramathi Samudi Shamala Devi Sekaran Veeranoot Nissapatorn Christophe Wiart	2016	Asian Pacific Journal of Tropical Medicine2016，9，9：	2
2	Post-cerebrovascular stroke depression (review)显示文摘	Wiart L	1997	Encephale1997，3，：	1
3	Kinetics of Pb and Pb-Ag anodes for zinc electrowinning显示文摘	Cachet C Rerolle C Wiart R	1996	Electrochem Acta1996，41，1：	1
4	Antiviral properties of ent-labdene diterpenes of Andrographis paniculata nees,inhibitors of herpes simplex virus type 1 显示文摘	Wiart C Kumar K Yusof M Y Hamimah H Fauzi Z M Sulaiman M	2005	Phytother Res2005，19，：	1
5	Assessment of baseline hemodynamic parameters within infarct progression areas in acute stroke patients using perfusion-weighted MRI显示文摘	Ritzenthaler T Cho TH Wiart M		0，，：	1
6	Fluoxetine in early poststroke depression:A double-blind plaeebocontrolled study显示文摘	Petit H Joseph P	2000	Stroke2000，31，：	1
7	MRI monitoring of neurinflammation in mouse focal ischemia显示文摘	Marlene Wiart Nathalie Davoust Jean-Baptiste Pialat	2007	Ameri- can Heart Association2007，38，1：	1
8	Epitaxial growth and electrode impedance of copper electrodeposits 显示文摘	CHASSAING E WIART R	1984	Electrochemical Aeta1984，29，5：	1
9	Fluoxetine in early post-stroke depression: A double-blind placebo-controlled study 显示文摘	Wiart L Petit H Joseph PA	2000	Stroke2000，31，：	1
10	A randomised double blind placebo controlled trial of botulinum toxin in the treatment of spastic foot in hemiparetic patients 显示文摘	Wiart L Bubos JL	1996	J Neurol Neurosurg Psychiatry1996，61，：	1
11	Fluoxetine in early poststroke depression:A double-blind placebo-controlled study显示文摘	Wiart L Petit H Joseph PA	2000	Stroke2000，31，：	1
12	Capsaicin and neurogenic detrusor hyperreflexia:a double-blind placebo-controlled study in 20 patients with spinal cord lesions 显示文摘	De Seze M Wiart L Joseph PA	1998	Neurourol Urodyn1998，17，5：	1
13	Pharmacological therapy of spinal cord injury during the acute phase显示文摘	Pointillart V Petitjean ME Wiart L	2000	Spinal Cord2000，38，2：	1
14	显示文摘		1997	Encephale1997，23，3：	1
15	Fluxetine in early post-stroke depression:A double-blind placebo controlled study显示文摘	Wiart L Petit H Joseph PA	2000	Stroke2000，31，：	1
16	Fluxetine in early post-stroke depression: A double-blind plaeebo- contwlled study 显示文摘	WIART L PEITR H JOSEPH P	2000	STROKE2000，31，8：	1
17	Characterization of hepatocellular carcinoma and coloreclal liver metastasis by means of perfusion MRI 显示文摘	Abdullah SS Pialat JB Wiart M	2008	J Magn Reson Imag2008，28，2：	1
18	Fluoxetine in early poststroke depression:a double-blind placebo-controlled study显示文摘	Petit H Joseph PA	2000	Stroke2000，31，8：	1
19	Pharma- cological therapy of spinal cord injury during the acute phase显示文摘	Pointillart V Petitjean ME Wiart L	2000	Spinal Cord2000，38，2：	1
20	Potential instabilities of lead-silver alloy anodes in acidic sulfate electrolyte 显示文摘	Cachet C Rerolle C Wiart R	1998	Journal of applied electrochemistry1998，28，2：	1

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