| 2 | Developing and Testing the Acceptability of Therapeutic Food for the Management of Severely Malnourished Children显示文摘Therapeutic foods for the treatment of malnutrition in children under age 5 years are mostly imported from developed countries by developing countries like Ghana. This comes with huge cost and puts pressure on health authorities when these supplies are limited. The objective of this study was therefore to develop and evaluate therapeutic food made from locally agricultural produce (banana, coconut water, soybean, sugar and vegetable oil) for the management of severely acute malnutrition in children under age 5 years. The proximate, mineral and microbial analyses were conducted on the developed product to ensure the standard falls within the requirement of WHO Protocol for the treatment of malnutrition in children. Sensory analysis was also done on the product using children under five years as the target group. The chemical analysis of product revealed energy and protein content of 95.96 kcal and 1.61 g per 100 g respectively, and percentage concentration of Calcium (0.74), Magnesium (1.09), Potassium (4.79), Sodium (0.17), Phosphorus (0.28), Iron (0.0080), Copper (0.0064), Manganese (0.0089) and Zinc (0.0174). The microbiological examination indicated aerobic plate count (20 cfu/mL), yeast count (8.5 cfu/mL), coliform count (3 cfu/mL) and zero count for both mould and E. Coli. This shows that, the developed product has the potential of treating malnutrition effectively in children under five years old. | Michael Wiafe Akenteng Reginald Adjetey Annan Herman Erick Lutterodt Victoria Pearl Dzogbefia Charles Apprey | 2017 | Journal of Food Science and Engineering2017，7，2： | 0 |
| 3 | Therapeutic Benefits of Vernonia amygdalina in the Treatment of Inflammation and Its Associated Diseases显示文摘Background:In the presence of a stimulus that disrupts homeostasis,the body elicits a response known as in-flammation.The inflammatory response is expected to restore the normal functioning of the body and initiate healing where necessary.However,the persistent activity of acute inflammation results in chronic inflammation which causes adverse consequences associated with diseases such as diabetes and arthritis.In traditional medical practice,Vernonia amygdalina is used to treat several ailments such as malaria,fever,diabetes,and inflammatory conditions such as those related to pain and swelling.Objective:This review seeks to explore and discuss the therapeutic benefits of V.amygdalina in the treatment of inflammation and its associated diseases.Methods:We reviewed the scientific literature indexed in PubMed,ScienceDirect and Springer,and discussed the reported anti-inflammatory properties of V.amygdalina and its curative activity in inflammation-associated diseases.Results:A total of 30 published articles were identified describing the therapeutic effect of V.amygdalina in predominately experimental models.The anti-inflammatory properties of V.amygdalina have been linked to the presence of bioactive phytoconstituents predominantly present in the leaves of the plant.Conclusions:Multiple studies have demonstrated that the aqueous and ethanolic extracts of V.amygdalina can inhibit the production of proinflammatory cytokines and enzymes in inflammatory cells,reducing inflammation and its associated complications.We critically appraise the current evidence,and discuss the potential use of this medicinal plant in the treatment of inflammatory conditions. | Du-Bois Asante Gideon Akuamoah Wiafe Korantema Mawuena Tsegah Nelson Kwabla Domey | 2024 | Clinical Complementary Medicine and Pharmacology2024，4，1： | 0 |
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