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| 1 | Screening and breeding of high taxol producing fungi by genome shuffling显示文摘To apply the fundamental principles of genome shuffling in breeding of taxol-producing fungi, Nodulisporium sylviform was used as starting strain in this work. The procedures of protoplast fusion and genome shuffling were studied. Three hereditarily stable strains with high taxol production were obtained by four cycles of genome shuffling. The qualitative and quantitative analysis of taxol produced was confirmed using thin-layer chromatography (TLC), high performance liquid chromatography (HPLC) and LC-MS. A high taxol producing fungus, Nodulisporium sylviform F4-26, was obtained, which produced 516.37 μg/L taxol. This value is 64.41% higher than that of the starting strain NCEU-1 and 31.52%―44.72% higher than that of the parent strains. | ZHAO Kai, PING WenXiang, ZHANG LiNa, LIU Jun, LIN Yan, JIN Tao & ZHOU DongPo Laboratory of Microbiology, College of Life Science, Heilongjiang University, Harbin 150080, China | 2008 | Science China(Life Sciences)2008，51，3： | 25 |
| 2 | Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B/pyrin domain-containing protein 3 pathway显示文摘OBJECTIVE: To evaluate the effectiveness of Sini powder for the treatment of non-alcoholic fatty liver disease(NAFLD) in rats and the molecular mechanisms involved.METHODS: A rat model of stress-induced NAFLD was established by a combination of long-term tethering and feeding of a high-fat, high-calorie diet. These rats were then intragastrically administered with either simvastatin, Sini powder, or vehicle for 1 week. The body mass and field test scores for each group were recorded weekly. Serum aspartate aminotransferase and alanine aminotransferase activities, and triglyceride, total cholesterol,and free fatty acid concentrations were measured.Liver tissue histopathology was examined on hematoxylin and eosin-stained paraffin sections and oil red O-stained frozen sections. The hepatic m RNA expression of nuclear factor kappa-B(NF-κB),NOD-, LRR-, and pyrin domain-containing protein 3(NLRP3), apoptosis-associated speck-like protein containing CARD(ASC), and caspase-1 were measured by reverse transcription-polymerase chain reaction(RT-PCR). The hepatic protein concentrations of NF-κB and NLRP3, ASC, caspase-1, interleukin-1β(IL-1β), interleukin-6(IL-6), and the serum concentrations of IL-1β and IL-6 were measured by enzyme-linked immunosorbent assay.RESULTS: Compared with the Blank group, rats in the Compound model group showed significant pathologic manifestations of NAFLD, and the expression of NF-κB, NLRP3, ASC, caspase-1, IL-1βand IL-6 were significantly higher(all P < 0.01). Both simvastatin and Sini powder significantly ameliorated the NAFLD pathology and the abnormal expression of NF-κB, NLRP3, ASC, caspase-1, IL-1β, and IL-6(all P < 0.01).CONCLUSION: Sini powder inhibits the inflamma-tory response in rats with NAFLD, which is mediated by NF-κB/NLRP3, IL-1β, and IL-6, reduces the effects of psychological stress, and improves lipid metabolism. Therefore, Sini powder may be effective for the treatment of stress-related NAFLD through multiple mechanisms. | Mu Jie Cheng Fafeng Wang Qingguo Wang Xueqian Zhu Wenxiang Ma Chongyang Yin Xiangjun Ren Beida Lian Yajun Du Xin Zhang Haixia Liu Shuling Zhang Shuang | 2020 | Journal of Traditional Chinese Medicine2020，40，2： | 9 |
| 3 | Altered expression of mitochondrial related genes in the native Tibetan placents by mitochondrial cDNA array analysis显示文摘Objective: To explore the mechanism of native Tibetan fetuses adaptation to hypoxia, we tried to find the different expression genes about mitochondrial function in the native Tibetan placents. Methods: In this study, the placents of native Tibetan and the high-altitude Han (ha-Han) were collected. After the total RNA extraction, the finally synthesized cDNAs were hybridized to mitochondrial array to find the altered expression genes between them. Then, the cytochrome c oxidase 17 (Cox17), dynactin 2 (DCTN2, also known as p50), and vascular endothelial growth factor receptor (VEGFR, also known as KDR) were chosen from the altered expression genes to further verify the array results using the SYBR Green real-time PCR. Because the altered expression genes (such as Cybb and Cox17) in the array results related to the activities of COXI and COXIV, the placental mitochondria activities of COXI and COXIV were measured to find their changes in the hypoxia. Results: By a standard of ≥1.5 or ≤0.67, there were 24 different expressed genes between the native Tibetan and the ha-Han placents, including 3 up-regulated genes and 21 down-regulated genes. These genes were related to energy metabolism, signal transduction, cell proliferation, electron transport, cell adhesion, nucleotide-excision repair. The array results of Cox17, DCTN2 and KDR were further verified by the real-time RT-PCR. Through the mitochondria respiration measurements, the activity of COXI in the native Tibetan placents were higher than that of ha-Han, there was no difference in COXIV activity between them. Conclusion: The altered mitochondrial related genes in the native Tibetan placents may have a role in the high altitude adaptation for fetuses through changing the activity of mitochondrial COX. | Luo Yongjun Gao Wenxiang Zhao Xiuxin SUO Lang Chen Li Liu Fuyu Song Tonglin Chen Jian Gao Yuqi | 2009 | Journal of Medical Colleges of PLA(China)2009，24，1： | 7 |
| 4 | High-speed silicon photonic Mach–Zehnder modulator at 2 μm显示文摘Recently,2-μm wave band has gained increasing interest due to its potential application for next-generation optical communication.But the development of 2-μm optical communications is substantially hampered by the modulation speed due to the device bandwidth constraints.Thus,a high-speed modulator is highly demanded at 2μm.Motivated by this prospect,we demonstrate a high-speed silicon Mach–Zehnder modulator for a 2-μm wave band.The device is configured as a single-ended push–pull structure with waveguide electrorefraction via the free carrier plasma effect.The modulator was fabricated via a multiproject wafer shuttle run at a commercial silicon photonic foundry.The modulation efficiency of a single arm is measured to be 1.6 V·cm.The high-speed characterization is also performed,and the modulation speed can reach 80 Gbit/s with 4-level pulse amplitude modulation(PAM-4)formats. | Xi Wang Weihong Shen Wenxiang Li Yingjie Liu Yong Yao Jiangbing Du Qinghai Song Ke Xu | 2021 | Photonics Research2021，9，4： | 7 |
| 5 | Effects of cerium incorporation on the catalytic oxidation of benzene over flame-made perovskite La_(1-x)Ce_xMnO_3 catalysts显示文摘Perovskite-type La_(1-x)Ce_xMnO_3(x = 0-10%) catalysts were prepared by flame spray pyrolysis and their activities during the catalytic oxidation of benzene were examined over the temperature range of100-450℃.The structural properties and reducibility of these materials were also characterized by X-ray diffraction(XRD),N_2 adsorption/desorption,H_2 temperature-programmed reduction(H_2-TPR) and X-ray photoelectron spectroscopy(XPS).The incorporation of Ce was found to improve the benzene oxidation activity,and the perovskite in which x was 0.1 exhibited the highest activity.Phase composition and surface elemental analyses indicated that non-stoichiometric compounds were present.The incorporation of Ce had a negligible effect on the specific surface area of the perovskites and hence this factor has little impact on the catalytic activity.Introduction of Ce4^(4+) resulted in modification of the chemical states of both B-site ions and oxygen species and facilitated the reducibility of the perovskite.The surface Mn^(4+)/Mn^(3+)ratio was increased as a result of Ce^(4+) substitution,while a decrease in the surface-adsorbed O/lattice O(O_(ads)/O_(latt)) ratio was observed.The relationship between the surface elemental ratios and catalytic activity was established to allow a better understanding of the process by which benzene is oxidized over perovskites. | Gang Liu Jiaqi Li Kun Yang Wenxiang Tang Haidi Liu Jun Yang Renliang Yue Yunfa Chen | 2015 | Particuology2015，13，2： | 6 |
| 6 | Design Bistatic Interferometric DEM Generation Algorithm and Its Theoretical Accuracy Analysis for LuTan-1 Satellites显示文摘LuTan-1(LT-1)is a constellation with two full-polarization L-band radar satellites designed by China,and the first satellite was scheduled to be launched in December 2021 and the second one in January 2022.The LT-1 will be operated for deformation monitoring in repeat-pass mode,and for DEM generation in bistatic mode,improving self-sufficiency of SAR data for the field of geology,earthquake,disaster reduction,geomatics,forestry and so on.In this paper,we focused on designing an algorithm for interferometric DEM generation using LT-1 bistatic satellites.The basic principle,main error sources and errors control of the DEM generation algorithm of LT-1 were systematically analyzed.The experiment results demonstrated that:①The implemented algorithm had rigorous resolution with a theoretic accuracy better than 0.03 m for DEM generation.②The errors in satellite velocity and Doppler centroid had no obvious effect on DEM accuracy and they could be neglected.While the errors in position,baseline,slant range and interferometric phase had a significant effect on DEM accuracy.And the DEM error caused by baseline error was dominated,followed by the slant range error,interferometric phase error and satellite position error.③To obtain an expected DEM accuracy of 2 m,the baseline error must be strictly controlled and its accuracy shall be 1.0 mm or better for Cross-Track and Normal-Direction component,respectively.And the slant range error and interferometric phase error shall be reasonably controlled.The research results were of great significance for accurately grasping the accuracy of LT-1 data products and their errors control,and could provide a scientific auxiliary basis for LT-1 in promoting global SAR technology progress and the generation of high-precision basic geographic data. | Bing XU Liqun LIU Zhiwei LI Yan ZHU Jingxin HOU Wenxiang MAO | 2022 | Journal of Geodesy and Geoinformation Science2022，5，1： | 6 |
| 7 | Toward emerging gallium oxide semiconductors:A roadmap显示文摘Owing to the advantages of ultra-wide bandgap and rich material systems,gallium oxide(Ga_(2)O_(3))has emerged as a highly viable semiconductor material for new researches.This article mainly focuses on the growth processes,material characteristics,and applications of Ga_(2)O_(3).Compared with single crystals and the epitaxial growth of other wide-bandgap semiconductors,large-size and high-quality��-Ga_(2)O_(3) single crystals can be efficiently grown with a low cost,making them highly competitive.Thanks to the availability of high-quality single crystals,epi-taxial films,and rich material systems,high-performance semiconductor devices based on Ga_(2)O_(3) go through a booming development in recent years.The defects and interfaces of Ga_(2)O_(3) are comprehensively analyzed owing to their significant influence on practical applications.In this study,the two most common applications of Ga_(2)O_(3) materials are introduced.The high breakdown electric field,high working temperature,and excellent Baliga’s figure-of-merit of Ga_(2)O_(3) represent an inspiring prospect for power electronic devices.In addition,the excellent absorption in deep-ultraviolet band provides new ideas for optoelectronic detectors and ensures the dramatic progress.Finally,the summary,challenges,and prospects of the Ga_(2)O_(3) materials and devices are presented and discussed. | Yuan Yuan Weibing Hao Wenxiang Mu Zhengpeng Wang Xuanhu Chen Qi Liu Guangwei Xu Chenlu Wang Hong Zhou Yanni Zou Xiaolong Zhao Zhitai Jia Jiandong Ye Jincheng Zhang Shibing Long Xutang Tao Rong Zhang Yue Hao | 2021 | Fundamental Research2021，1，6： | 5 |
| 8 | Mitochondrial localization of ORF346 causes pollen abortion in alloplasmic male sterility显示文摘The Nsa cytoplasmic male sterility(CMS) system confers stable male sterility and offers great potential for production of hybrid seeds in oilseed rape. However, genes responsible for male sterility in Nsa CMS have not been identified. By mitochondrial genome sequencing of Nsa CMS and its maintainer line,we identified in an Nsa CMS line several chimeric genes encoding hypothetical proteins harboring transmembrane domains. One novel chimeric gene orf346 showed high identity with cox1 at the 50 terminal region and was co-transcribed with nad3 and rps12 genes. Transgenic plants of orf346 fused with or without mitochondrial targeting peptide conferred complete male sterility in Arabidopsis. ORF346 was mitochondrion-localized. Expression of orf346 in Escherichia coli inhibited bacterial growth, with excessive accumulation of reactive oxygen species and decreased ATP content. These results reveal a link between the newly identified mitochondrial gene orf346 and the abortion of Nsa CMS. Inadequate energy supply and excessive accumulation of reactive oxygen species may account for pollen abortion in Nsa CMS plants. | Shifei Sang Hongtao Cheng Mengyu Hao Bingli Ding Desheng Mei Hui Wang Wenxiang Wang Jia Liu Li Fu Kede Liu Qiong Hu | 2021 | The Crop Journal2021，9，6： | 5 |
| 9 | A new unequal-weighted triple-frequency first order ionosphere correction algorithm and its application in COMPASS显示文摘As the introduction of triple-frequency signals in GNSS,the multi-frequency ionosphere correction technology has been fast developing.References indicate that the triple-frequency second order ionosphere correction is worse than the dual-frequency first order ionosphere correction because of the larger noise amplification factor.On the assumption that the variances of three frequency pseudoranges were equal,other references presented the triple-frequency first order ionosphere correction,which proved worse or better than the dual-frequency first order correction in different situations.In practice,the PN code rate,carrier-to-noise ratio,parameters of DLL and multipath effect of each frequency are not the same,so three frequency pseudorange variances are unequal.Under this consideration,a new unequal-weighted triple-frequency first order ionosphere correction algorithm,which minimizes the variance of the pseudorange ionosphere-free combination,is proposed in this paper.It is found that conventional dual-frequency first-order correction algorithms and the equal-weighted triple-frequency first order correction algorithm are special cases of the new algorithm.A new pseudorange variance estimation method based on the three carrier combination is also introduced.Theoretical analysis shows that the new algorithm is optimal.The experiment with COMPASS G3 satellite observations demonstrates that the ionosphere-free pseudorange combination variance of the new algorithm is smaller than traditional multi-frequency correction algorithms. | WenXiang Liu WeiHua Mou FeiXue Wang | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，3： | 5 |
| 10 | Large-scale synthesis of hierarchical MnO_2 for benzene catalytic oxidation显示文摘Hierarchical sea-urchin-shaped manganese oxide microspheres were synthesized via a tacile metnoa based on the reaction between KMnO_4 and MnSO_4 in HNO_3 solution at 50 C.The average diameter of the microspheres is ~850 nm.The microspheres consist of a core of diameter of ~800 nm and nanorods of width ~50 nm.The nanorods exist at the edge of the core.The Brunauer-Emmett-Teller surface area of the sea-urchin-shaped microspheres is 259.4 m^2/g.A possible formation mechanism of the hierarchical sea-urchin-shaped microspheres is proposed.The temperature for 90%conversion of benzene(T_(90)%) on the hierarchical urchin-shaped MnO_2 microspheres is about 218℃. | Dongyan Li Genli Shen Wenxiang Tang Haidi Liu Yunfa Chen | 2014 | Particuology2014，12，3： | 4 |
| 11 | Algorithm of Micro-Grooving and Imaging Processing for the Generation of High-Resolution Structural Color Images显示文摘The use of submicron structures for structural coloration of surfaces has broad applications for color filters,projection displays,virtual reality,and anti-counterfeiting.Currently,structural color images lack high resolution due to low manufacturing accuracy.In this study,the axial-feed fly cutting(AFC)method is proposed to fabricate submicron grooves for the diffraction of visible light to create structural color images.We establish the relationship between the color information in the pixels of the original image and the parameters of the array units corresponding to the pixels.An algorithm to determine groove spacing and the tool path is established,and array units with the desired groove spacing are machined to reproduce the structural color images.The submicron grooves fabricated by AFC have high quality and good consistency.Due to the excellent diffraction performance of the machined grooves,images with high saturation and resolution can be reproduced.It is verified that images with various colors can be efficiently fabricated using the proposed method and algorithm. | Tianfeng Zhou Yupeng He Tianxing Wang Xiaobin Dong Peng Liu Wenxiang Zhao Yao Hu Jiwang Yan | 2020 | Nanomanufacturing and Metrology2020，3，3： | 4 |
| 12 | Design and synthesis of porous non-noble metal oxides for catalytic removal of VOCs显示文摘The design and synthesis of highly active non-noble metal oxide catalysts, such as transition- and rare-earth-metal oxides, have attracted significant attention because of their high efficiency and low cost and the resultant potential applications for the degradation of volatile organic compounds(VOCs). The structure-activity relationships have been well-studied and used to facilitate design of the structure and composition of highly active catalysts. Recently, non-noble metal oxides with porous structures have been used as catalysts for deep oxidation of VOCs, such as aromatic hydrocarbons, aliphatic compounds, aldehydes, and alcohols, with comparable activities to their noble metal counterparts. This review summarizes the growing literature regarding the use of porous metal oxides for the catalytic removal of VOCs, with emphasis on design of the composition and structure and typical synthetic technologies. | Wenxiang Tang Gang Liu Dongyan Li Haidi Liu Xiaofeng Wu Ning Han Yunfa Chen | 2015 | Science China Chemistry2015，58，9： | 4 |
| 13 | Determination of structure-activity relationships between fentanyl analogs and human μ-opioid receptors based on active binding site models显示文摘Fentanyl is a potent and widely used clinical narcotic analgesic,as well as a highly selective μ-opioid agonist.The present study established a homologous model of the human μ-opioid receptor;an intercomparison of three types of μ-opioid receptor protein sequence homologous rates was made.The secondary receptor structure was predicted,the model reliability was assessed and verified using the Ramachandran plot and ProTab analysis.The predictive ability of the CoMFA model was further validated using an external test set.Using the Surflex-Dock program,a series of fentanyl analog molecules were docked to the receptor,the calculation results from Biopolymer/SiteID showed that the receptor had a deep binding area situated in the extracellular side of the transmembrane domains(TM) among TM3,TM5,TM6,and TM7.Results suggested that there might be 5 active areas in the receptor.The important residues were Asp147,Tyr148,and Tyr149 in TM3,Trp293,and His297 in TM6,and Trp318,His319,Ile322,and Tyr326 in TM7,which were located at the 5 active areas.The best fentanyl docking orientation position was the piperidine ring,which was nearly perpendicular to the membrane surface in the 7 TM domains.Molecular dynamic simulations were applied to evaluate potential relationships between ligand conformation and fentanyl substitution. | Ming Liu Xiaoli Liu Ping Wan Qiangsan Wu Wenxiang Hu | 2011 | Neural Regeneration Research2011，6，4： | 3 |
| 14 | Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing显示文摘Gastric cancer(GC) is a highly heterogeneous disease with multiple cellular types and poor prognosis.However, the cellular evolution and molecular basis of GC at the individual intra-tumor level has not been well demonstrated. We performed single-cell whole exome sequencing to detect somatic singlenucleotide variants(SNVs) and significantly mutated genes(SMGs) among 34 tumor cells and 9 normal cells from a patient with GC. The Complete Prediction for Protein Conformation(CPPC) approach directly predicting the folding conformation of the protein 3D structure with Protein Folding Shape Code, combined with functional experiments were used to confirm the characterization of mutated SMGs in GC cells. We identified 201 somatic SNVs, including 117 non-synonymous mutations in GC cells. Further analysis identified 24 significant mutated genes(SMGs) in single cells, for which a single amino acid change might affect protein conformation. Among them, two genes(CDC27 and FLG) that were mutated only in single cells but not in the corresponding tumor tissue, were recurrently present in another GC tissue cohort, and may play a potential role to promote carcinogenesis, as confirmed by functional characterization. Our findings showed a mutational landscape of GC at intra-tumor level for the first time and provided opportunities for understanding the heterogeneity and individualized target therapy for this disease. | Lihua Peng Rui Xing Dongbing Liu Li Bao Wenxiang Cheng Hongyi Wang Yuan Yu Xiaofeng Liu Lu Jiang Yan Wu Zhongxue An Qiaoyi Liang Ryong Nam Kim Young Kee Shin Huanming Yang Jian Wang Jun Yu Xiuqing Zhang Xun Xu Jiaan Yang Kui Wu Shida Zhu Youyong Lu | 2019 | Science Bulletin2019，64，4： | 3 |
| 15 | Selection and Characterization of a Novel Photoperiod-Sensitive Male Sterile Line in Upland Cotton显示文摘高地棉花(Gossypium hirsutum L.) 显示出强壮的杂种优势。然而,杂种优势广泛地没由于混合种子生产的高费用被利用。一根光周期敏感的基因男无菌的线的创造能实质地在高地棉花减少混合种子生产的费用。有带绿色的标记的如此的异种被空间变化在接近地球的轨道发现,它的特点在 4 年在 Anyang 和 Sanya 的选择以后是稳定的,中国。当温度比 21.5 敶高时,这异种与一个 1112.5h 光周期是肥沃的吗? | Jianhui Ma Hengling Wei Ji Liu Meizhen Song Chaoyou Pang Long Wang Wenxiang Zhang Shuli Fan Shuxun Yu | 2013 | Journal of Integrative Plant Biology2013，55，7： | 3 |
| 16 | A review of the techniques for the mold manufacturing of micro/nanostructures for precision glass molding显示文摘Micro/nanostructured components play an important role in micro-optics and optical engineering,tribology and surface engineering,and biological and biomedical engineering,among other fields.Precision glass molding technology is the most efficient method of manufacturing micro/nanostructured glass components,the premise of which is meld manufacturing with complementary micro/nanostructures.Numerous mold manufacturing methods have been developed to fabricate extremely small and high-quality micro/nanostructures to satisfy the demands of functional micro/nanostructured glass components for various applications.Moreover,the service performance of the mold should also be carefully considered.This paper reviews a variety of technologies for manufacturing micro/nanostructured molds.The authors begin with an introduction of the extreme requirements of mold materials.The following section provides a detailed survey of the existing micro/nanostructured mold manufacturing techniques and their corresponding mold materials,including nonmechanical and mechanical methods.This paper concludes with a detailed discussion of the authors recent research on nickel-phosphorus(Ni-P)mold manufacturing and its service performance. | Tianfeng Zhou Yupeng He Tianxing Wang Zhanchen Zhu Ruzhen Xu Qian Yu Bin Zhao Wenxiang Zhao Peng Liu Xibin Wang | 2021 | International Journal of Extreme Manufacturing2021，3，4： | 3 |
| 17 | Multi-objective Optimization Design of Inset-surface Permanent Magnet Machine Considering Deterministic and Robust Performances显示文摘The inset-surface permanent magnet(ISPM)machine can achieve the desired electromagnetic performance according to the traditional deterministic design.However,the reliability and quality of the machine may be affected by the essential manufacturing tolerances and unavoidable noise factors in mass production.To address this weakness,a comprehensive multi-objective optimization design method is proposed,in which robust optimization is performed after the deterministic design.The response surface method is first adopted to establish the optimization objective equation.Afterward,the sample points are obtained via Monte Carlo simulation considering the design-variable uncertainty.The Design for Six Sigma approach is adopted to ensure the robustness of the design model.Furthermore,the barebones multi-objective particle swarm optimization algorithm is used to obtain a compromise solution.A prototype is manufactured to evaluate the effectiveness of the proposed method.According to the finite-element analysis and experimental tests,the electromagnetic performance and reliability of the machine are significantly enhanced with the proposed method. | Gaohong Xu Zexin Jia Wenxiang Zhao Qian Chen Guohai Liu | 2021 | Chinese Journal of Electrical Engineering2021，7，3： | 2 |
| 18 | Pharmacophore Screening on Piperidinecarboxamides Derivatives Based on GALAHAD and CoMFA Models显示文摘以便发现新奇 anticonvulsant 药, anticonvulsant 禁止者屏蔽的 pharmacophore 被强制。有为数据集(GALAHAD ) 和分析(CoMFA ) 学习的比较的分子的地的 Hypermolecular 排列的线性赋值的基因算法被联合实现我们的研究。第一,多重模型基于高活跃的分子用 GALAHAG 被产生。第二,他们中的几个用 CoMFA 学习被验证。最后,一从从测试集合训练集合和有希望的预兆的力量的 q2 的好价值 simutaneously 基于一个模型被获得。一个模型作为最合理的 pharmacophore 模型被选择了。CoMFA 学习的结果基于模型, 1 建议位、静电的相互作用起了重要作用。 | Liu, Ming Wu, Qiangsan Hu, Wenxiang | 2011 | Chinese Journal of Chemistry2011，29，6： | 2 |
| 19 | High dynamic output feedback robust control of cascaded extended state observer显示文摘High dynamic tracking performance is a key technical index of hydraulic flight motion simulator(HFMS).However,the strong nonlinearities,various model uncertainties and measurement noise in hydraulic actuation systems limit the high dynamic performance improvement.In this paper,the outer axis frame of a HFMS is taken as a case study and its nonlinear dynamic model with consideration of strong nonlinearities,matched and mismatched uncertainties is established.A novel cascaded extended state observer(ESO)is proposed to estimate the unavailable system states to avoid the adverse effect of measurement noise on control performance.Meanwhile,the designed cascaded ESO also produces estimates of matched and mismatched uncertainties.Then,an output feedback robust controller(OFRC)is proposed by integrating the cascaded ESO with a robust integral of the sign of the error(RISE)feedback based on the backstepping framework.The proposed controller achieves compensation of both matched and mismatched model uncertainties in an output feedback form.Theoretical analysis indicates that the proposed OFRC ensures the boundedness of all closed-loop system signals in the presence of matched and mismatched timevarying model uncertainties.Excellent asymptotic tracking performance can also be obtained when the model uncertainties are time-invariant.Comparative experimental results show that the proposed OFRC achieves significant performance improvement compared with the extensively employed PI control with velocity feedforward(VFPI). | Wenxiang DENG Jianyong YAO Zongxia JIAO Xiaochao LIU | 2022 | Chinese Journal of Aeronautics2022，35，7： | 2 |
| 20 | Alleviating the crosstalk effect via a fine-moulded light-blocking matrix for colour-converted micro-LED display with a 122% NTSC gamut显示文摘One of the major challenges when fabricating high gamut colour-converted micro-light-emitting diodes(LEDs)displays is severe crosstalk effect among adjacent pixels because of the wide view-angle feature of micro-LED chips.In this study,potential factors that contribute to the crosstalk effect were systematically simulated.We observed that precisely filling the space between each micro-LED chip with a light blocking matrix(LBM)can be a promising solution to alleviate this risk.After careful investigations,a press-assisted moulding technique was demonstrated to be an effective approach of fabricating the LBM.Nevertheless,experimental observations further revealed that residual black LBM on the surface of micro-LEDs severely reduces the brightness,thereby compromising the display performance.This problem was successfully addressed by employing a plasma etching technique to efficiently extract the trapped light.Eventually,a top-emitting blue micro-LED-based backlight fine-moulded with a black LBM was developed and combined with red and green quantum dot colour-conversion layers for full-colour display.The colour gamut of our manufactured display prototype can cover as high as 122%that of the National Television Standards Committee. | Yongming Yin Zhiping Hu Muhammad Umair Ali Miao Duan Yongwei Wu Ming Liu Wenxiang Peng Jun Hou Dongze Li Xin Zhang Hong Meng | 2022 | Light(Advanced Manufacturing)2022，3，3： | 2 |
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