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| 1 | Status of hyperhomocysteinemia in China: results from the China Stroke High-risk Population Screening Program, 2018显示文摘A nationwide survey was conducted from October 2018 to September 2019 to assess the prevalence of hyperhomocysteinemia(Hhcy)and its influencing factors in China.A standardized questionnaire was used to collect information.Hhcy was defined as the level of serum homocysteine(HCY)≥15.0µmol/L.The H-type hypertension(HHYP)was defined as hypertension with an elevated serum HCY(≥15.0µmol/L).Finally,110551 residents≥40 years of age from 31 provinces in the mainland of China were included.Overall,the median serum HCY level was 10.9µmol/L(interquartile range 7.9–15.1).A total of 28633 participants(25.9%)were defined as Hhcy.The Hhcy prevalence ranged from 7.9%in Shanghai to 56.8%in Tianjin.The data showed that serum HCY levels were associated with age,male gender,cigarette smoking,hypertension,diabetes,ethnicity,endurance in exercise(inverse),and fruit and vegetable intake(inverse).In addition,15486 participants were defined as HHYP,and the rate was 14.0%.HHYP was an independent predictor of stroke with an adjusted odds ratio of 1.752(95%CI 1.338–2.105).The geographical distribution pattern of the Hhcy epidemic reflects dynamic differences,and national strategies should be carried out to further improve the care of patients with Hhcy across China. | Wenjun Tu Feng Yan Baohua Chao Xunming Ji Longde Wang | 2021 | Frontiers of Medicine2021，15，6： | 12 |
| 2 | Soft measurement of wood defects based on LDA feature fusion and compressed sensor images显示文摘We proposed a detection method for wood defects based on linear discriminant analysis(LDA) and the use of compressed sensor images. Wood surface images were captured, using a camera Oscar F810C IRF camera,and then the image segmentation was performed, and the defect features were extracted from wood board images. To reduce the processing time, LDA algorithm was used to integrate these features and reduce their dimensions. Features after fusion were used to construct a data dictionary and a compressed sensor was designed to recognize the wood defects types. Of the three major defect types, 50 images live knots, dead knots, and cracks were used to test the effects of this method. The average time for feature fusion and classification was 0.446 ms with the classification accuracy of 94%. | Chao Li Yizhuo Zhang Wenjun Tu Cao Jun Hao Liang Huiling Yu | 2017 | Journal of Forestry Research2017，28，6： | 6 |
| 3 | Low Ca diet leads to increased Ca retention by changing the gut flora and ileal pH value in laying hens显示文摘Osteoporosis is a common degenerative metabolic bone disease in caged laying hens.Intensive egg production mobilizing large amounts of Ca from bone for eggshell formation,consequently leading to Ca deficiency,has been recognized as a critical factor causing osteoporosis in commercial laying hens.The aim of this study was to examine the effect of Ca deficiency on the function of the gut microbiotaebone axis and related egg production traits and bone health in laying hens.Twenty-four 48-week-old laying hens were fed a control diet(Control,3.72%)or a low Ca diet(LC,2.04%)for 60 d(n=12).Compared to the Control hens,the LC hens had higher levels of alkaline phosphatase and tartrate resistant acid phosphatase(P<0.05)with lower bone strength,eggshell thickness,and eggshell strength(P<0.05).In addition,the LC hens had higher plasma estradiol concentrations,while having lower concentrations of interleukin-1(IL-1)and IL-6.The LC hens also had a lower pH value in the ileum with an increased Ca retention.The principal co-ordinates analysis showed significantly separate cecal microbiota populations between the Control and LC hens.The Prevotellaceae_UCG-001,Subdoligranulum,Peptococcus,and Eubacterium_hallii_group(P<0.05)were higher,while the CHKC1001 and Sutterella(P<0.05)were lower at the genus level in the LC hens.In addition,Prevotellaceae_UCG-001,Subdoligranulum and Eubacter-ium_hallii_group had a negative correlation,while Sutterella was positively correlated with ileal pH values.The transcriptome analysis revealed that the low Ca diet caused 20 and 31 genes to be signifi-cantly up-and down-regulated,respectively.The gene expressions of cystic fibrosis transmembrane conductance regulator,solute carrier family 26 member 3 of the anion exchangers,and mitogen-activated protein kinase 12 of pro-inflammatory factors were lower in the LC birds,which was corre-lated with the lower ileal pH values.These results suggest that the hens with low Ca diet-induced osteoporosis have an increased intestinal Ca retention with a decreased ileal pH value,correlated with the changes in Prevotellaceae_UCG-001,Subdoligranulum,and Eubacterium_hallii_group of beneficial genera.The results provide insights for further understanding and preventing osteoporosis in laying hens. | Sha Jiang Xinyu Zou Miao Mao Mi Zhang Wenjun Tu Meilan Jin | 2023 | Animal Nutrition2023，，2： | 1 |
| 4 | Psychological Effects of False-Positive Results in Expanded Newborn Screening in China显示文摘 | WENJUN TU JIAN HE HUI CHEN | 2012 | Plos one2012，7，4： | 1 |
| 5 | Application of Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) in Screening of High Risk Children with Inherited Metabolic Diseases in Northern China显示文摘 | Wenjun Tu Xiaotao Song Fang Dai James Jian Ho | 2010 | Journal of Pediatric Endocrinology and Metabolism2010，，12： | 1 |
| 6 | Enhancing the Intermolecular Interactions of Ladder-Type Heteroheptacene-Based Nonfullerene Acceptors for Efficient Polymer Solar Cells by Incorporating Asymmetric Side Chains显示文摘Asymmetric nonfullerene acceptors(NFAs)possess larger dipole moments and stronger intermolecular bonding energy than their symmetric counterparts thereby making them promising candidates for high-performance polymer solar cells(PSCs).Herein,we report twoefficient acceptor–donor–acceptor(A–D–A)type NFAs(M14 and M18)with asymmetric side chains that show enhanced intermolecular interactions compared with their corresponding counterparts(M17 and M19)based on symmetric side chains.Furthermore,M14 and M18 exhibit elevated lowest unoccupiedmolecular orbitals and smallerπ–πstacking distances in comparison with M17 and M19,respectively.In combination with the benchmark polymer donor of PM6,the PM6:M14 blend affords superior charge transport properties,and more importantly,an increased power conversion efficiency(PCE)of 15.49%in comparison with the M17-based counterpart(13.01%PCE).Similarly,the asymmetric M18-based blend also shows a higher PCE of 13.00%than the M19-based blend(11.55%).Through further interface engineering,the bestperforming M14-based device delivers an enhanced PCE of 16.46%,which represents a record value among all asymmetric A–D–A type NFAs.Our results provide new insights into the design of asymmetric NFAs with enhanced intermolecular interactions for highperformance PSCs. | Qisheng Tu Wenjun Zheng Yunlong Ma Ming Zhang Zhijian Li Dongdong Cai Pan Yin Jinyun Wang Shan-Ci Chen Feng Liu Qingdong Zheng | 2023 | CCS Chemistry2023，5，2： | 0 |
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