5篇
您的检索式：作者名="Weining Luo"
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| 1 | TRDMT1 exhibited protective effects against LPS-induced inflammation in rats through TLR4-NF-κB/MAPK-TNF-αpathway显示文摘Background:Inflammation is a complex physiological and pathological process.Although many types of inflammation are well characterized,their physiological func-tions are largely unknown.tRNA aspartic acid methyltransferase 1(TRDMT1)has been implicated as a stress-related protein,but its intrinsic biological role is unclear.Methods:We constructed a Trdmt1 knockout rat and adopted the LPS-induced sepsis model.Survival curve,histopathological examination,expression of inflammatory fac-tors,and protein level of TLR4 pathway were analyzed.Results:Trdmt1 deletion had no obvious impact on development and growth.Trdmt1 de-letion slightly increased the mortality during aging.Our data showed that Trdmt1 strongly responded in LPS-treated rats,and Trdmt1 knockout rats were vulnerable to LPS treat-ment with declined survival rate.We also observed more aggravated tissue damage and more cumulative functional cell degeneration in LPS-treated knockout rats compared with control rats.Further studies showed upregulated TNF-αlevel in liver,spleen,lung,and serum tissues,which may be explained by enhanced p65 and p38 phosphorylation.Conclusions:Our data demonstrated that Trdmt1 plays a protective role in inflamma-tion by regulating the TLR4-NF-κB/MAPK-TNF-αpathway.This work provides useful information to understand the TRDMT1 function in inflammation. | Zhengguang Li Xiaolong Qi Xu Zhang Lei Yu Lijuan Gao Weining Kong Wei Chen Wei Dong Lijun Luo Dan Lu Lianfeng Zhang Yuanwu Ma | 2022 | Animal Models and Experimental Medicine2022，5，2： | 5 |
| 2 | Dithiol treatments enhancing the efficiency of hybrid solar cells based on PTB7 and CdSe nanorods显示文摘We report the fabrication of polymer/inorganic hybrid solar cells (HSCs) based on CdSe nanorods (NRs) and the semiconducting polymer PTB7. The power conversion efficiency of HSCs can be significantly enhanced by engineering the polymer/nanocrystal interface with ethanedithiol (EDT) and 1,4-benzenedithiol (1,4-BDT) treatments and reached 2.58% and 2.79%, respectively. These results were preferable to that of a pyridine-coated NR-based device (1.75%). This improvement was attributed to the thiol groups of EDT and 1,4-BDT, which can tightly coordinate the Cd ions to form Cd-thialate on CdSe NR surfaces, thereby effectively passivating the NR surface and reducing the active layer defects. Therefore, the rate of exciton generation and dissociation was enhanced and led to the improvement of the device performance. | Weining Luo Tonggang Jiu Chaoyang Kuang Bairu Li Fushen Lu Junfeng Fang | 2015 | Nano Research2015，8，9： | 2 |
| 3 | Control of citrus postharvest green and blue mold and sour rot by tea saponin combined with imazalil and prochloraz显示文摘 | Weining Hao Meiying Hu Jianjun Luo | 2010 | Postharvest Biology and Technology2010，56，1： | 1 |
| 4 | Control of citrus postharvest green and blue mold and sour rot by tea saponin combined with imazalil and prochloraz显示文摘 | Weining Hao Guohua Zhong Meiying Hu Jianjun Luo Qunfang Weng Muhammad Rizwan-ul-Haq | 2009 | Postharvest Biology and Technology2009，，1： | 1 |
| 5 | Implementation of le- arning path in process control model 显示文摘 | Luo Junzhou Kong Weining Ge Liang | 2010 | The Computer Jour- nal2010，53，2： | 1 |
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