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107篇 您的检索式：作者名="Weigmann"

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	题名	作者	年代	出处	被引量
1	Regulation of the intestinal immune system by flavonoids and its utility in chronic inflammatory bowel disease显示文摘Flavonoids are phytochemicals which can regulate the activity of the intestinal immune system. In patients with chronic inflammatory bowel disease(IBD) there is an overexpression and imbalance of the components of the inflammatory immune reactions which are chronically activated. Suppression of inflammation can be achieved by anti-inflammatory drugs which are used in clinical medicine but these can cause serious side effects. Flavonoids can have natural immunosuppressive properties and inhibit the activation of immune cells and its effectors(chemokines, TNF-, cytokines). Phytochemicals such as flavonoids bind to the nuclear Ah(aryl hydrocarbon)-receptor thereby stimulating protective enzyme activities. As shown by clinical evidence in patients and by experimental work some flavonoids(apigenin, epigallocatechin gallate) were effective in the inhibition of inflammation. Instead of or additionally to anti-inflammatory drugs flavonoids can be used in IBD patients to treat the over-reactive immunologic system. This is accomplished by upregulation of the Ah-receptor. Flavonoids interact with toll-like receptors expressing on the surface of immune cells, then they were internalized to the cytosol and transferred into the nucleus, where they were attached to the Ah-receptor. The Ah-receptor binds to the Ah-R nuclear translocator and via Ah response element beneficial protective enzymes and cytokines are induced, leading to upregulation of the anti-inflammatory system.	Harald Peter Hoensch Benno Weigmann	2018	World Journal of Gastroenterology2018，24，8：	10
2	The role of cationic conditioning compounds in reinforcement of the cuticula显示文摘	Sigrid B R Kamath Y K Weigmann H D	2003	J Cosmet Sci2003，54，：	1
3	显示文摘	Neurath MF Weigmann B Finotto S	2002	J Exp Med2002，195，9：	1
4	The in situ polymerization of vinyl monomers in polyester yarns显示文摘	YAIR Avny REBENFELD L WEIGMANN H-D	1978	Journal of Applied Polymer Science1978，22，1：	1
5	Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases显示文摘	H. Ali B. Weigmann M.F. Neurath E.M. Collnot M. Windbergs C.-M. Lehr	2014	Journal of Controlled Release2014，，：	1
6	The Role of Surfactant Concentration on the Aqueous Stability of a MonoAzo Disperse Dye显示文摘	Weigmann H D	1976	Textile Research Journal1976，4，：	1
7	The Bantam gene regulates Drosophila growth 显示文摘	Hipfner D R Weigmann K Cohen S M	2002	Genetics2002，161，：	1
8	Chemically induced mouse models of intestinal inflammation显示文摘	Wirtz S Neu Weigmann B	2007	Nature proto- cols2007，2，：	1
9	The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn' s disease 显示文摘	Neurath MF Weigmann B Finotto S	2002	J Exp Med2002，195，9：	1
10	Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory diseases显示文摘	Mudter J Weigmann B Bartsch B	2005	Am J Gastroenterol2005，100，1：	1
11	Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice 显示文摘	Lademann J Weigmann H Rickmeyer C	1999	Skin Pharmacol Appl Skin Physiol1999，12，5：	1
12	Detection of p53 autoantibodys in sera of gastric cancer patients and prognostic relevance 显示文摘	Wtarl P Weigmann F Meye A	1997	Scand J Gastroentrol1997，32，11：	1
13	Automated determination of amisulpride by liquid chromatography with column switching and spectrophotometric detection显示文摘	Sachse J Hartter S Weigmann H	2003	J Chromatogr B Analyt Technol Biomed Life Sci2003，784，2：	1
14	The Role of Surfaetant Concentration on the Aqueous Stability of a MonoAzo Disperse Dye显示文摘	Knox B H Weigmann H D	1976	Textile Research Journal1976，46，4：	1
15	Prominin, a novel mi-cro villi-specific polytopic membrane protein of the apical surface ofepithelial cells,is targeted toplasmalemmal protrusions of non-epi-thelial cells 显示文摘	Weigmann A Corbeil D Hellwig A	1997	Proc Natl Acad Sci USA1997，94，12：	1
16	Comparison of transepidermal water loss and spectroscopic absorbance to quantify changes of the stratum corneum after tape stripping显示文摘	Weigmann HJ Ulrich J Schanzer S	2005	Skin Pharmacol Physiol2005，18，4：	1
17	IL-28A is a key regulator of T-cell-mediated liver injury via the T-box transcription factor T-bet显示文摘	Siebler J Wirtz S Weigmann B	2007	Gastroenterology2007，132，1：	1
18	Comparison of transepidermalwater loss and spectroscopic absorbance to quantify changes of thestratum corneum after tape stripping 显示文摘	Weigmann HJ Ulrich J Schanzer S	2005	Skin Pharmacol Physiol2005，18，4：	1
19	The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease显示文摘	Neurath MF Weigmann B Finotto S	2002	J Exp Med2002，195，9：	1
20	AC133 hematopoietic stem cell antigen:human homologue of mouse kidney prominin or distinct member of a novel protein family?显示文摘	Per K Weigmann A	1998	Blood1998，91，7：	1

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