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186篇 您的检索式：作者名="Weichselbaum"

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	题名	作者	年代	出处	被引量
1	Type 3 innate lymphoid cell-derived lymphotoxin prevents microbiota-dependent inflammation显示文摘Splenomegaly is a well-known phenomenon typically associated with inflammation.However,the underlying cause of this phenotype has not been well characterized.Furthermore,the splenomegaly phenotype seen in lymphotoxin(LT)signaling-deficient mice is characterized by increased numbers of splenocytes and splenic neutrophils.Splenomegaly,as well as the related phenotype of increased lymphocyte counts in non-lymphoid tissues,is thought to result from the absence of secondary lymphoid tissues in LT-deficient mice.We now present evidence that mice deficient in LTα1β2 or LTβR develop splenomegaly and increased numbers of lymphocytes in non-lymphoid tissues in a microbiota-dependent manner.Antibiotic administration to LTα1β2-or LTβR-deficient mice reduces splenomegaly.Furthermore,re-derived germ-free Ltbr−/−mice do not exhibit splenomegaly or increased inflammation in non-lymphoid tissues compared to specific pathogen-free Ltbr−/−mice.By using various LTβ-and LTβR-conditional knockout mice,we demonstrate that retinoic acid-related orphan receptorγT-positive type 3 innate lymphoid cells provide the required active LT signaling to prevent the development of splenomegaly.Thus,this study demonstrates the importance of LT-mediated immune responses for the prevention of splenomegaly and systemic inflammation induced by microbiota.	Yuan Zhang Tae-Jin Kim Joanna A Wroblewska Vera Tesic Vaibhav Upadhyay Ralph R Weichselbaum Alexei V Tumanov Hong Tang Xiaohuan Guo Haidong Tang Yang-Xin Fu	2018	Cellular & Molecular Immunology2018，15，7：	3
2	Nasopharyngeal carcinoma显示文摘	Vokes EE Liebowitz DN Weichselbaum RR	1997	Lancet1997，350，：	3
3	Radiogenetic therapy: on the interaction of viral therapy and ionizing radiation for improving local control of tumors显示文摘	Advani S Chmura S J Weichselbaum R R	1997	Semin Oncol1997，24，6：	2
4	Gene therapy targeting by ionizing radiation 显示文摘	Weichselbaum RR Hallahan DE Sukhatme VP	1992	Int J Radiat Oncol Biol Phys1992，24，3：	1
5	Concomitant chemoradiotherapy: rationale and chnical experience in patients with solid tumors显示文摘	Vokes E E Weichselbaum R R	1990	Journal of Clinical Oncology1990，8，5：	1
6	Molecular targeting of gene therapy and radiotherapy 显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
7	Molecular targeting of gene therapy and radio therapy 显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
8	Molecular targeting of gene therapy and radiotherapy显示文摘	Weichselbaum RR Kufe DW Advani SJ	2001	Acta Oncol2001，40，6：	1
9	A reaction rate method for ammonia and blood urea nitrogen utilizing a pentacyanonitrosyloferrate catalyzed Berthelot reaction显示文摘	Weichselbaum T.E J.C. Hagerty H.B. Mark Jr		0，，：	1
10	Oncomitant chemotherapy rational and chnical experience in patients with solid tumors显示文摘	Vokes EE Weichselbaum RR		0，，05：	1
11	Radiation as an immune modulator显示文摘	Burnette B Weichselbaum RR	2013	Semin Radiat Oncol2013，23，4：	1
12	Concomitant chemotherapy:rational and clinical experience in patients with solid tumors显示文摘	Vokes EE Weichselbaum RR		0，，05：	1
13	Gene therapy targeted by ionizing radiation显示文摘	Weichselbaum RR Halahan DE Sukhatme VP	1992	Int J Radiat Oncol Biol Phys1992，24，3：	1
14	Head and neck cancer显示文摘	Vokes EE Weichselbaum RR Lippman SM	1993	N Engl J Med1993，328，3：	1
15	Rediobiologicalcharacterization of 53 human tumor cell lines 显示文摘	Weichselbaum RR Rotmensch j Ahmed - swan S	1989	Int J Rediat Biol1989，56，：	1
16	Gene therapy: the challenges of translating laboratory research into clinical practice 显示文摘	Connell PP Weichselbaum RR	2003	J Clin Oncol2003，21，12：	1
17	Gene therapy targeted by radiation preferentially radiosensitizes tumor cells显示文摘	Weichselbaum RR Hallahan DE Beckett MA	1994	Cancer Res1994，54，16：	1
18	Radiation-induced tumour necrosis factor-α expression:clinical application of transcriptional and physical targeting of gene therapy显示文摘	Weichselbaum RR Kufe DW Hellman S	2002	Lancet Oncol2002，3，11：	1
19	European nutri- tion and health report 2004 显示文摘	Elmadfa I Weichselbaum E Konig J	2005	Forum Nutr2005，58，：	1
20	Gene therapy targeted by radiation preferentially radio- sensitizes tumor cells显示文摘	Weichselbaum RR Hallahan DE Beckett MA	1994	Cancer Res1994，54，16：	1

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