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| 1 | Telephone screening tests for functionally impaired hearing: current use in seven countries and development of a US version 显示文摘 | Watson CS WKidd GR Miller JD | 2012 | J Am Acad Audiol2012，23，10： | 1 |
| 2 | Low vision in the geriatric population:rehabilitation andmanagement显示文摘 | Watson GR | 2001 | J Am Geriatr Soc2001，49，3： | 1 |
| 3 | Effects and safety of natriuretic peptides as treatment of cirrhotic ascites:A systematic review and meta-analysis显示文摘BACKGROUND Natriuretic peptides are involved in the cascade of pathophysiological events occurring in liver cirrhosis,counterbalancing vasoconstriction and anti-natriuretic factors.The effects of natriuretic peptides as treatment of cirrhotic ascites have been investigated only in small studies,and definitive results are lacking.AIM To examine the effects and safety of natriuretic peptides in cirrhosis patients with ascites.METHODS We searched MEDLINE,Web of Science,Scopus,Cochrane Library and Embase for all available studies applying intravenous administration of any natriuretic peptide to patients suffering from cirrhotic ascites.Inclusion was not limited by treatment duration or dose,or by follow-up duration.Both randomised controlled trials and non-randomised studies were eligible for inclusion.The primary outcome was change in renal sodium excretion.Secondary outcomes included safety measures and changes in renal water excretion,plasma aldosterone concentration,and plasma renin activity.RESULTS Twenty-two studies were included.Atrial natriuretic peptide(ANP)was the only intensively studied treatment.Sodium excretion increased in response to continuous ANP infusion and was more pronounced when infusion rates of>30 ng/kg/min were administered compared with≤30 ng/kg/min(P<0.01).Moreover,natriuresis was significantly higher in study subgroups with mild/moderate ascites compared with moderate/severe and refractory ascites(P<0.01).ANP infusions increased renal water excretion,although without reaching a statistically significant dose-response gradient.Plasma aldosterone concentration and plasma renin activity were significantly lower at baseline in study subgroups achieving a negative sodium balance in response to an ANP administration compared with treatment non-responders(P<0.01).Blood pressure decreases occurred less frequently when ANP doses≤30 ng/kg/min were applied.The quality of evidence for a natriuretic response to ANP was low,mainly due to small sample sizes and considerable between-study heterogeneity.Data were sparse for the other natriuretic peptides;B-type natriuretic peptide and urodilatin.CONCLUSION Intravenous ANP infusions increase sodium excretion in patients with cirrhotic ascites.Continuous infusion rates>30 ng/kg/min are the most effective.However,safety increases with infusion rates≤30 ng/kg/min. | Rasmus Hvidbjerg Gantzel Mikkel Breinholt Kjær Peter Jepsen Niels Kristian Aagaard Hugh Watson Lise Lotte Gluud Henning Grønbæk | 2022 | World Journal of Hepatology2022，14，4： | 1 |
| 4 | The partial molar enthalpies in aqueous solution of some amino acids with polar and non-polar side chains显示文摘 | Humphrey RS Hedwig GR Watson ID | 1980 | J Chem Thermodyn1980，12，： | 1 |
| 5 | Medical student ap praisal of interactive computer assisted learning programs embedded in a general pathology course显示文摘 | Reid WA Harvey J Watson GR | 2000 | J Pathol2000，191，4： | 1 |
| 6 | Medical student appraisal of interactive computer-assisted learning programs embedded in a general pathology course 显示文摘 | Reid WA Harvey J Watson GR | 2000 | J Pathol2000，191，： | 1 |
| 7 | Medical student appraisal of interactive computer-assisted learning programs embedded in a general pathology course显示文摘 | Reid WA Harvey J Watson GR | 2000 | J Pathol2000，191，4： | 1 |
| 8 | Hyperpnoea during and immediately after exercise in man: evidence for motor cortical involvement 显示文摘 | Fink GR Adams L Watson JD | 1995 | J Physiol1995，489，3： | 1 |
| 9 | Medical student appraisal of interactive computer-assisted learning programs embedded in a general pathology course显示文摘 | Harvey J Watson GR | 2000 | J Pathol2000，191，4： | 1 |
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