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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines 显示文摘 | MAEDA M MURAKAMI Y WATARI K | 2015 | Lung Cancer2015，87，3： | 1 |
| 3 | Twin roll casting of aluminum alloy strips 显示文摘 | HAGA T TKAHASHI K IKAWAAND M WATARI H | 2004 | Journal of Materials Processing Technology2004，153，4： | 1 |
| 4 | Rapid, sensitive and simple detectiota methods for koi herpesvirus using loop-mediated isothermal amplification 显示文摘 | Yoshino M Watari H Kojima T | 2009 | Microbiol Immunol2009，53，7： | 1 |
| 5 | MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1显示文摘 | Dong P Kaneuchi M Watari H | 2011 | Mol Cancer2011，10，： | 1 |
| 6 | Construction of flocculation yeast cells (Saccharomyces cerevisiae) by mating or protoplast fusion using a yeast cell containing the flocculation gene FLO5显示文摘 | Watari J Kudo N Kamimura M | | Agricultural and Biological Chemistry0，54，： | 1 |
| 7 | Cerebral tissue oxygen saturation during percutaneous cardiopulmonary support in a canine model of respiratory failure 显示文摘 | Wada H Watari M Sueda T | 2000 | Artif Organ2000，24，8： | 1 |
| 8 | Physics of nanomechanical biosensing on cantilever arrays 显示文摘 | Sushko M L Harding J H Shluger A L Mckendry R A Watari M | 2008 | Advanced Materials2008，20，： | 1 |
| 9 | GRK6 phosphorylates IκBα atSer (32)//Ser (36)andenhancesTNF-α-induced inflammation 显示文摘 | Ohba Y Nakaya M Watari K | 2015 | Biochem Biophys Res Commun2015，461，2： | 1 |
| 10 | Breeding of brewer* syeast by hybridization between a top-fermenting yeastSaccharomyces cerevisiae and a cryophilic yeastSaccharomyces bayanus显示文摘 | Sato M Kishimoto M Watari J | 2002 | J Biosci Bioeng2002，，5： | 1 |
| 11 | The extra domain A of fibronectin activates Toll-like receptor 4显示文摘 | Okamura Y Watari M Jerud ES | 2001 | J Biol Chem2001，276，10： | 1 |
| 12 | The extra domain A of fibronectin activates Toll-like receptor 4 显示文摘 | Okamura Y Watari M Jerud ES | 2001 | J Biol Chem2001，276，10： | 1 |
| 13 | An advanced aged case of in- trapulmonary metastasis of non-small cell lung cancer sue- cessfully controlled with S-1 capsule therapy alone for an extended period 显示文摘 | Katayama T Watari M | 2007 | Gan To Kagaku Ryoho2007，34，5： | 1 |
| 14 | Carbon nanotubes functionalized with fibroblast growth factor accelerate proliferation of bone marrow-derived stromal cells and bone formation显示文摘 | Eri Hirata Cécilia Ménard-Moyon Enrica Venturelli Hiroko Takita Fumio Watari Alberto Bianco Atsuro Yokoyama | 2013 | Nanotechnology2013，，43： | 1 |
| 15 | Urodynamic study on postsurgical bladder function in cervical cancer treated with systematic nerve-sparing radical hysterectomy 显示文摘 | Todo Y Kuwabara M Watari H | 2006 | Int J Gynecol Cancer2006，16，1： | 1 |
| 16 | Densification and thermal conductivity of AlN doped with Y2O3, CaO and Li2O 显示文摘 | Watari K Valecillos M C Brito M E | 1996 | J Am Ceram Soc1996，79，12： | 1 |
| 17 | Multi-functional gene ASY/Nogo/RTN-X/RTN4: apoptosis, tumor suppression, and inhibition of neuronal regeneration显示文摘 | Watari A Yulsudo M | 2003 | Apoptosis2003，8，1： | 1 |
| 18 | Uredynamic study on posts-urgical bladder function in cervical cancer treated with systematic nerve-sparing radical hysterectomy显示文摘 | Todo Y Kuwabara M Watari H | 2006 | Int J Gynecol Cancer2006，16，1： | 1 |
| 19 | Urodynamic study on postsurgical bladder function in cervical cancer treated with systematic nerve-sparing radical hysterectomy显示文摘 | Todo Y Kuwabara M Watari H | | 0，，01： | 1 |
| 20 | Effective sintering aids for low-temperature sintering of AlN ceramics 显示文摘 | Watari K Hwang H J Toriyama M | 1999 | J Mater Res1999，14，4： | 1 |
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