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| 1 | The complete reference genome for grapevine (Vitis vinifera L.) genetics and breeding显示文摘Grapevine is one of the most economically important crops worldwide.However,the previous versions of the grapevine reference genome tipically consist of thousands of fragments with missing centromeres and telomeres,limiting the accessibility of the repetitive sequences,the centromeric and telomeric regions,and the study of inheritance of important agronomic traits in these regions.Here,we assembled a telomere-to-telomere(T2T)gap-free reference genome for the cultivar PN40024 using PacBio HiFi long reads.The T2T reference genome(PN_T2T)is 69 Mb longer with 9018 more genes identified than the 12X.v0 version.We annotated 67%repetitive sequences,19 centromeres and 36 telomeres,and incorporated gene annotations of previous versions into the PN_T2T assembly.We detected a total of 377 gene clusters,which showed associations with complex traits,such as aroma and disease resistance.Even though PN40024 derives from nine generations of selfing,we still found nine genomic hotspots of heterozygous sites associated with biological processes,such as the oxidation–reduction process and protein phosphorylation.The fully annotated complete reference genome therefore constitutes an important resource for grapevine genetic studies and breeding programs. | Xiaoya Shi Shuo Cao Xu Wang Siyang Huang Yue Wang Zhongjie Liu Wenwen Liu Xiangpeng Leng Yanling Peng Nan Wang Yiwen Wang Zhiyao Ma Xiaodong Xu Fan Zhang Hui Xue Haixia Zhong Yi Wang Kekun Zhang Amandine Velt Komlan Avia Daniela Holtgräwe Jérôme Grimplet JoséTomás Matus Doreen Ware Xinyu Wu Haibo Wang Chonghuai Liu Yuling Fang Camille Rustenholz Zongming Cheng Hua Xiao Yongfeng Zhou | 2023 | Horticulture Research2023，10，5： | 3 |
| 2 | Peptide lipid interactions of the betahairpin antimicrobial peptide tachyplesin and its linear derivatives from solid state NMR显示文摘 | Doherty T Waring A J Hong M | 2006 | Bioehim Biophys Aeta2006，1758，9： | 1 |
| 3 | The MOS 36-Item Short-Form Health Survey (SF-36) : Ⅲ : Tests of data quality, scaling assumptions and reliability across diverse patient groups显示文摘 | Mcklorney C A Ware J E Lu J F R | 1994 | Med Care1994，32，1： | 1 |
| 4 | Conflict Reduction in MapGeneralization Using Iterative Improvement 显示文摘 | WARE J M JONES C B | 1998 | Geoln-formatica1998，2，4： | 1 |
| 5 | A controlled, three - part trial to investigate the barrier function and skin hydration properties of six skin protectants 显示文摘 | Hoggarth A Waring M Alexander J | 2005 | Ostomy Wound Manage2005，51，12： | 1 |
| 6 | Membrane thinning effect of the betasheet antimicrobial protegrin显示文摘 | Heller W T Waring A J Lehrer R I | 2000 | Biochemistry2000，39，： | 1 |
| 7 | Hepcidin, a urinary antimierobial peptide synthesized in the liver 显示文摘 | Park CH Valore EV Waring A J | 2001 | J Biol Chem2001，276，： | 1 |
| 8 | LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator显示文摘 | Davide N Mauri Reinhard Ebner Rebecca I Montgomery Kristine D Kochel Timothy C Cheung Guo-Liang Yu Steve Ruben Marianne Murphy Roselyn J Eisenberg Gary H Cohen Patricia G Spear Carl F Ware | 1998 | Immunity1998，，： | 1 |
| 9 | A procedure for automatically correction invalid fat triangles occurring in triangulated contour data显示文摘 | | 1998 | Computers & Geosciences1998，24，2： | 1 |
| 10 | Evaluating translations of health status questionnaires显示文摘 | Ware J E Keller S D Gandek B | 1995 | Int J Technol Assess in Health Care1995，11，3： | 1 |
| 11 | Predicting fine root production and turnover by monitoring root starch and soil temperature显示文摘 | Marashall J D Waring R H | 1985 | Can J For Res1985，15，： | 1 |
| 12 | Gliotoxin and related epipolythiodiox- opiperazines 显示文摘 | Waring P Beaver J | 1996 | Gen Pharmacol1996，27，8： | 1 |
| 13 | Conflict Reduction in Map Generalization Using Iterative Improvement显示文摘 | WARE J M JONES C B | 1998 | Geoinformatica1998，2，4： | 1 |
| 14 | Reflections of the self:how self-esteem determines decision framing and increases risk taking显示文摘 | McElroy T Seta J J Waring D A | 2007 | Journal of Behavioral Decision Making2007，，20： | 1 |
| 15 | Hepcidin, a urinary antimicrobial peptide synthesized in the liver显示文摘 | Park C H Valore E V Waring A J | 2001 | J Biol Chem2001，276，11： | 1 |
| 16 | Comparison of methods of estimating leaf-area index in old-growth Douglas-fir显示文摘 | Marshall J D Waring R H | 1986 | Ecology1986，67，： | 1 |
| 17 | Analysis and control of transient overvoltages on UHV transmission systems 显示文摘 | FAKHERI A J BHATT N B WARE B J | 1983 | IEEE T-PAS1983，102，10： | 1 |
| 18 | Antithrombotic strategies in patients with acute coronary syndromes undergoing early invasive management: one-year results from the ACUITY trial显示文摘 | STONE G W WARE J H BERTRAND M E | 2007 | JAMA2007，298，21： | 1 |
| 19 | Rate-limiting process in photosynthesis at saturating light intensities 显示文摘 | Wareing P F Khalifa M M Treharne K J | 1968 | Nature1968，220，： | 1 |
| 20 | Hydrophobic surfactant proteins and their analogues显示文摘 | Walther F J Waring A J Sherman MA | 2007 | Neonatology2007，91，4： | 1 |
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