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| 1 | SHRIMP U-Pb dating for a K-bentonite bed in the Tieling Formation,North China显示文摘A SHRIMP U-Pb zircon age of 1437±21 Ma was obtained for a recently discovered K-bentonite bed in the Tieling Formation,situated northeast of Beijing at the boundary between Liaoning and Hebei provinces,on the northern margin of the North China Craton(NCC).The SHRIMP U-Pb age places Tieling Formation near the end of the Calymmian Period of the early Mesoproterozoic Era.In addition,a SHRIMP U-Pb zircon date of 1372±18 Ma was acquired for K-bentonite beds in the overlying,dark-shale-dominated Xiamaling Formation from the same location northeast of Beijing.This date assigns a similar Mid-Mesoproterozoic(Ectasian Period) age for the Xiamaling Formation,as have previously determined dates from other sections northwest of Beijing.These dates indicate that the Tieling and Xiamaling formations,as well as the related succession in the eastern part of the Yanshan Mountains,represented by the well-known Meso-to Neoproterozoic standard section in Jixian,can be correlated well with sections northwest of Beijing in the western part of the Yanshan Mountains.In other words,the boundary between the Calymmian and Ectasian periods in the northern parts of the NCC is marked by the unconformity between the Tieling and Xiamaling formations in the northern NCC.This boundary was previously ascribed to the 'Qinyu Orogeny' and thought to be of Grenville age.In this regard,the conventional 'Qinyu Orogeny' should now be regarded as a short-lived regional uplift during Early Mesoproterozoic time,rather than a result from the Grenvillian assembly of the NCC to the Rodinia Supercontinent(~1.0 Ga). | SU WenBo LI HuaiKun HUFF W D ETTENSOHN F R ZHANG ShiHong ZHOU HongYing WAN YuSheng | 2010 | Chinese Science Bulletin2010，55，29： | 30 |
| 2 | Mechanosignaling activation of TGFβmaintains intervertebral disc homeostasis显示文摘Intervertebral disc(IVD) degeneration is the leading cause of disability with no disease-modifying treatment.IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal(NC) cells to maintain IVD homeostasis. Here we report that mechanical stress can result in excessive integrin α_vβ_6-mediated activation of transforming growth factor beta(TGFβ), decreased NC cell vacuoles, and increased matrix proteoglycan production, and results in degenerative disc disease(DDD). Knockout of TGFβ type II receptor(TβRII) or integrin α_v in the NC cells inhibited functional activity of postnatal NC cells and also resulted in DDD under mechanical loading.Administration of RGD peptide, TGFβ, and α_vβ_6-neutralizing antibodies attenuated IVD degeneration. Thus,integrin-mediated activation of TGFβ plays a critical role in mechanical signaling transduction to regulate IVD cell function and homeostasis. Manipulation of this signaling pathway may be a potential therapeutic target to modify DDD. | Qin Bian Lei Ma Amit Jain Janet L Crane Khaled Kebaish Mei Wan Zhengdong Zhang X Edward Guo Paul D Sponseller Cheryle A Seguin Lee H Riley Yongjun Wang Xu Cao | 2017 | Bone Research2017，5，1： | 9 |
| 3 | Liver transplantation:Fifty years of experience显示文摘Since 1963,when the first human liver transplantation(LT)was performed by Thomas Starzl,the world has witnessed 50 years of development in surgical techniques,immunosuppression,organ allocation,donor selection,and the indications and contraindications for LT.This has led to the mainstream,wellestablished procedure that has saved innumerable lives worldwide.Today,there are hundreds of liver transplant centres in over 80 countries.This review aims to describe the main aspects of LT regarding the progressive changes that have occurred over the years.We herein review historical aspects since the first experimental studies and the first attempts at human transplantation.We also provide an overview of immunosuppressive agents and their potential side effects,the evolution of the indications and contraindications of LT,the evolution of survival according to different time periods,and the evolution of methods of organ allocation. | Alice Tung Wan Song Vivian Iida Avelino-Silva Rafael Antonio Arruda Pecora Vincenzo Pugliese Luiz Augusto Carneiro D'Albuquerque Edson Abdala | 2014 | World Journal of Gastroenterology2014，20，18： | 8 |
| 4 | Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010显示文摘 | Gonghuan Yang Yu Wang Yixin Zeng George F Gao Xiaofeng Liang Maigeng Zhou Xia Wan Shicheng Yu Yuhong Jiang Mohsen Naghavi Theo Vos Haidong Wang Alan D Lopez Christopher JL Murray | 2013 | The Lancet . 2013 (9882)2013，，9882： | 4 |
| 5 | Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010显示文摘 | Gonghuan Yang Yu Wang Yixin Zeng George F Gao Xiaofeng Liang Maigeng Zhou Xia Wan Shicheng Yu Yuhong Jiang Mohsen Naghavi Theo Vos Haidong Wang Alan D Lopez Christopher JL Murray | 2013 | The Lancet2013，，9882： | 3 |
| 6 | Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010显示文摘 | Gonghuan Yang Yu Wang Yixin Zeng George F Gao Xiaofeng Liang Maigeng Zhou Xia Wan Shicheng Yu Yuhong Jiang Mohsen Naghavi Theo Vos Haidong Wang Alan D Lopez Christopher JL Murray | 2013 | 2013 (9882)2013，，9882： | 3 |
| 7 | Genetic transformation of wheat mediated by Agrobacterium tumefaciens显示文摘 | Cheng M Fry J E Pang S Zhou H Hironaka C M Duncan D R Conner T W Wan Y | 1997 | Plant Physiol1997，，： | 2 |
| 8 | 新生儿继发于筛窦炎的眼眶脓肿(英文)显示文摘骨膜下脓肿是眼眶蜂窝织炎的一种,以脓和渗出液汇集在眼眶内骨膜下为特点。对于新生儿,眼眶脓肿非常罕见。我们报告1例年龄为26d的右眼患有严重眼眶蜂窝织炎的女患儿。眼眶和副鼻窦CT扫描显示右眼眶蜂窝织炎并内侧骨膜下和眼眶后部脓肿。眼分泌物培养见葡萄球菌生长,经用先锋霉素和甲硝唑静脉注射和经内窥镜鼻窦手术行急诊脓肿引流,恢复良好。通过内窥镜的鼻窦引流手术是预防更严重的并发症的首选治疗。 | C D Che Mahiran K Wan Mariny J Alagaratnam W H Wan Hazabbah | 2008 | 国际眼科杂志2008，8，4： | 2 |
| 9 | Preparation and characterization of gelatin gel with a gradient structure 显示文摘 | Wang Y L Cheng G X Yao K D | 2000 | Polymer Int2000，49，12： | 1 |
| 10 | Clinical measures of disease severity and outcome in psoriasis:a critical appraisal of their quality显示文摘 | ASHCROFT D M WAN PO A L WILLIAMS H C | 1999 | Br J Dermatol1999，141，2： | 1 |
| 11 | Development of the East Asian mon- soon: Mineralogical and sedimentologic records in the northern South China Sea since 20 Ma 显示文摘 | Wan S Li A Clift P D | 2007 | Palaeogeography Palaeoclimatology Palaeoecology2007，254，： | 1 |
| 12 | Acclimatization of soil respiration to warming in a tall grass prairie显示文摘 | Luo Y Wan S H ui D | 2001 | Nature2001，413，： | 1 |
| 13 | Risk based voltage security assessment显示文摘 | Hua Wan McCalley J D Vittal V | 2000 | IEEE Transactions on Power Systems2000，15，4： | 1 |
| 14 | Telangiectatic osteosarcoma:radiologic-pathologic comparison显示文摘 | Mark D M Suphanee wan Jaovisidha H Thomas T | 2003 | Radiology2003，229，： | 1 |
| 15 | Automated detection of malignant features in confocal microscopy on superficial spreading melanoma versus nevi显示文摘 | GAREAU D HENNESSY R WAN E | 2010 | Journal of Biomedical Optics2010，15，6： | 1 |
| 16 | Silicon isotope fractionation in bamboo and its significance to the biogeochemical cycle of silicon显示文摘 | DING T P ZHOU J X WAN D F | 2008 | Geochimica et Cosmochimica Acta2008，72，5： | 1 |
| 17 | An amplified fragment length poly- morphism map of the silkworm 显示文摘 | Tan Y D Wan C L Lu C | 2001 | Genetics2001，157，3： | 1 |
| 18 | Effect of drip irrigation with saline water on tomato ( Lycopersicon esculentum Mill) yield and water use in semi-humid area显示文摘 | Wan S Q Kang Y H Wang D | 2007 | Agricultural Water Management2007，90，： | 1 |
| 19 | Study of a combined sulfur autotrophic with proton-exchange membraneelectrodialyticdeni- trification technology: Sulfate control and pH balance显示文摘 | Wan D J Liu H J Liu R P | 2011 | Bioresource Technology2011，102，10： | 1 |
| 20 | BnC15 and BnATA20,the different putative components,control anther development in Brassica napus 显示文摘 | Wan L L Hu Q Hong D F | 2012 | Gene2012，507，1： | 1 |
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