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| 1 | Use of exclusive enteral nutrition in adults with Crohn's disease: A review显示文摘Exclusive enteral nutrition(EEN)is well-established as a first line therapy instead of corticosteroid(CS)therapy to treat active Crohn’s disease(CD)in children.It also has been shown to have benefits over and above induction of disease remission in paediatric populations.However,other than in Japanese populations,this intervention is not routinely utilised in adults.To investigate potential reasons for variation in response between adult studies of EEN and CS therapy.The Ovid database was searched over a 6-mo period.Articles directly comparing EEN and CS therapy in adults were included.Eleven articles were identified.EEN therapy remission rates varied considerably.Poor compliance with EEN therapy due to unpalatable formula was an issue in half of the studies.Remission rates of studies that only included patients with previously untreated/new CD were higher than studies including patients with both existing and new disease.There was limited evidence to determine if disease location,duration of disease or age of diagnosis affected EEN therapy outcomes.There is some evidence to support the use of EEN as a treatment option for a select group of adults,namely those motivated to adhere to an EEN regimen and possibly those newly diagnosed with CD.In addition,the use of more palatable formulas could improve treatment compliance. | Catherine L Wall Andrew S Day Richard B Gearry | 2013 | World Journal of Gastroenterology2013，19，43： | 15 |
| 2 | Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease:A definitive diagnostic test?显示文摘AIM: To investigate the utility of scintigraphic studies in predicting response to laparoscopic fundoplication(LF) for chronic laryngopharyngeal reflux symptoms.METHODS: Patients with upper aero-digestive symptoms that remained undiagnosed after a period of 2 mo were studied with conventional p H and manometric studies. Patients mainly complained of cough, sore throat, dysphonia and globus. These patients were imaged after ingestion of 99m-technetium diethylene triamine pentaacetic acid. Studies were quantified with time activity curves over the pharynx, upper and lower oesophagus and background. Late studies of the lungs were obtained for aspiration. Patients underwent LF with post-operative review at 3 mo after surgery.RESULTS: Thirty four patients(20 F, 14 M) with an average age of 57 years and average duration of symptoms of 4.8 years were studied. Twenty four hour p H and manometry studies were abnormal in all patients. On scintigraphy, 27/34 patients demonstrated pharyngeal contamination and a rising or flat pharyngeal curve. Lung aspiration was evident in 50% of patients. There was evidence of pulmonary aspiration in 17 of 34 patients in the delayed study(50%). Pharyngeal contamination was found in 27 patients. All patients with aspiration showed pharyngeal contamination. In the 17 patients with aspiration, graphical time activity curve showed rising activity in the pharynx in 9 patients and a flat curve in 8 patients. In those 17 patients without pulmonary aspiration, 29%(5 patients) had either a rising or flat pharyngeal graph. A rising or flat curve predicted aspiration with a positive predictive value of 77% and a negative predictive valueof 100%. Over 90% of patients reported a satisfactory symptomatic response to LF with an acceptable sideeffect profile. CONCLUSION: Scintigraphic reflux studies offer a good screening tool for pharyngeal contamination and aspiration in patients with gastroesophageal reflux disease. | Gregory L Falk John Beattie Alvin Ing SE Falk Michael Magee Leticia Burton Hans Van der Wall | 2015 | World Journal of Gastroenterology2015，21，12： | 2 |
| 3 | Characterization of frequency stability in precision frequency sources显示文摘 | RUTMAN J WALLS F L | 1991 | Proceedings of IEEE1991，79，6： | 1 |
| 4 | Effect of implanted Cl^- and deposited oxides on pitting behavior of aluminum显示文摘 | Sema L M Johnson C M Wall F D | 2005 | Journal of the Electrochemical Society2005，152，7： | 1 |
| 5 | Fragmentation Behavior of Pyrite and Calcite During High-Temperature Processing and Mathematical Simulation 显示文摘 | Yan L Gupta R P Wall T F | 2001 | Energy and Fuels2001，15，2： | 1 |
| 6 | Differences in reactivity of pulverised coal in air (Oz/Nz) and oxy- fuel (Oz/CO2) conditions 显示文摘 | Rathnam R K Elliott L K Wall T F Liu Y Moghtaderi B | 2009 | Fuel ProcessingTechnology2009，90，6： | 1 |
| 7 | Both physical fitness and acute exercise regulate nitric oxide formation in healthy humans 显示文摘 | Jungersten L Ambring A Wall B | 1997 | J Appl Physiol1997，82，3： | 1 |
| 8 | Difference in reactivity of pulverized coal in (OJN~) and oxy-fuel(O~/CO2) conditions 显示文摘 | Rathnam R K Elliott L K Wall T F | 2009 | Fuel Processing Technology2009，90，： | 1 |
| 9 | Silverleaf whitefly in- duces salicylic acid defenses and suppresses effectual jasmonic acid defenses 显示文摘 | Zarate S I Kempema L A Walling L L | 2007 | Plant Physiology2007，143，： | 1 |
| 10 | Does caregiver burden medi- ate the effects of behavioral disturbances on nursing home admissions 显示文摘 | Gaugler J E Wall M M Kane R L | 2011 | Am J Geriatr Psychiatry2011，19，6： | 1 |
| 11 | Spatial and temporal variability in sediment denitrification within an agriculturally influenced reservoir 显示文摘 | Wall L (3 Tank J L Royer T V | 2005 | Biogeochemistry2005，76，1： | 1 |
| 12 | Optimization model for planning radial distribution networks显示文摘 | Wall D L Tompson G L Northcote-Green J E D | 1979 | IEEE Trans on Power Apparatus and Systems1979，98，3： | 1 |
| 13 | HMGBl release by in-flammasomes显示文摘 | Vande Walle L Kanncganti TD Lamkanfi M | 2011 | Virulence2011，2，2： | 1 |
| 14 | A quick, direct method for the determination of activation energy from thermogravimetric data 显示文摘 | Wall L A | 1966 | J Polym Sci Part B1966，4，5： | 1 |
| 15 | Storage of sediment-associated nutrients and contaminants in river channel and floodplain systems显示文摘 | Walling D E Owens P N Carter J Leeks G J L Lewis S Meharg A A and Wright J | 2003 | Applied Geochemistry2003，18，： | 1 |
| 16 | Developing depleted uranium and gold cocktail hohlraums for the National Ignition Facility显示文摘 | WILKENS H L NIKROO A WALL D R | 2007 | [JP2]Phys Plasmas2007，14，05： | 1 |
| 17 | The depolymerization of polymethylene and po- lyethylene 显示文摘 | Wall L A Madorsky S I Brown D W | 1954 | J Am Chem Soc1954，76，： | 1 |
| 18 | Consumer Attitudes toward Canadian Made-in Versus Imported Products显示文摘 | WALL M HESWP L | 1986 | Journal of the Academy of Marketing Science1986，14，2： | 1 |
| 19 | The isolation and structure of taxol,a novel antileukemic and antitumor agent from taxus brevifolia显示文摘 | Wani M C Tayor H L Wall M E | 1971 | Journal of American Chemistry1971，27，7： | 1 |
| 20 | Oxy-fuel combustion technology for coal-fired power generation显示文摘 | BUHRE B J P ELLIOTT L K SHENG C D GUPTA R P WALL T F | 2005 | Prog Energy Combust2005，31，4： | 1 |
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