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| 1 | Current approaches in treatment of triple-negative breast cancer显示文摘Triple-negative breast cancer(TNBC) is diagnosed more frequently in younger and premenopausal women and is highly prevalent in African American women. TNBC is a term derived from tumors that are characterized by the absence of ER, Pg R, and HER2. So patients with TNBC do not benefit from hormonal or trastuzumab-based therapies. TNBCs are biologically aggressive, although some reports suggest that they respond to chemotherapy better than other types of breast cancer, prognosis remains poor. This is due to: shortened disease-free interval in the adjuvant and neoadjuvant setting and a more aggressive course in the metastatic setting. | Hanan Ahmed Wahba Hend Ahmed El-Hadaad | 2015 | Cancer Biology & Medicine2015，12，2： | 20 |
| 2 | Smoothing noisy data with spline functions显示文摘 | Peter Craven Grace Wahba | 1978 | Numerische Mathematik1978，，4： | 3 |
| 3 | Adjuvant Pelvic Radiotherapy vs.Sequential Chemoradiotherapy for High-Risk StageⅠ-ⅡEndometrial Carcinoma显示文摘Objective To explore if the addition of adjuvant chemotherapy with paclitaxel and carboplatin to radiotherapy confers an advantage for overall survival(OAS),and progression free survival(PFS);to assess the incidence of relapses over standard pelvic radiotherapy; and to evaluate the related toxicity in high-risk stageⅠ-Ⅱendometrial carcinoma Methods Medical records were reviewed to identify high-risk stageⅠ-Ⅱendometrial carcinoma cases treated in the Clinical Oncology and Nuclear Medicine department between 2002 and 2008 with adjuvant radiotherapy alone(armⅠ)(57 patients) or with sequential carboplatin(AUC5-6) and paclitaxel(135-175 mg/m^2) with radiotherapy(armⅡ)(51 patients).Radiotherapy was performed through the four-field box technique at doses of 45-50 Gy(1.8 Gy/day×5 days/week). Results The toxicity was manageable and predominantly hematologic with a grade 3 neutropenia and thrombocytopenia in 9.8% and 6% of the patients in armⅠand armⅡ,respectively,without febrile neutropenia.All patients experienced hair loss. Chemoradiotherapy arm was associated with a lower incidence rate of relapse(9.8% vs.22.7% ).After a median follow-up period of 48 months,the 5-year OAS and PFS rates for chemoradiotherapy-treated patients were significantly more favorable than those who did not receive chemotherapy(P=0.02 and 0.03,respectively).In armⅠ,the OAS and PFS rates were 73.7% and 66.7% compared with those in armⅡ,whose rates were 90.2% and 84.3% . Conclusions Adjuvant chemoradiation with paclitaxel and carboplatin improved the survival rates and decreased the recurrence rates in patients with high-risk stageⅠ-Ⅱendometrial carcinoma.Chemotherapy was associated with an acceptable rate of toxicity. However,a prospective study with a larger number of patients is needed to define a standard adjuvant treatment for high-risk stageⅠ-Ⅱendometrial carcinoma. | Hend Ahmed El-Hadaad Hanan Ahmed Wahba Anas Mohamed Gamal Tamer Dawod | 2012 | Clinical oncology and cancer resexreh2012，9，3： | 3 |
| 4 | A 15 Gbps-NRZ, 30 Gbps-PAM4, 120 mA laser diode driver implemented in 0.15-μm GaAs E-mode pHEMT technology显示文摘This paper presents the design and testing of a 15 Gbps non-return-to-zero(NRZ),30 Gbps 4-level pulse amplitude modulation(PAM4)configurable laser diode driver(LDD)implemented in 0.15-μm GaAs E-mode pHEMT technology.The driver bandwidth is enhanced by utilizing cross-coupled neutralization capacitors across the output stage.The output transmission-line back-termination,which absorbs signal reflections from the imperfectly matched load,is performed passively with on-chip 50-Ωresistors.The proposed 30 Gbps PAM4 LDD is implemented by combining two 15 Gbps-NRZ LDDs,as the high and low amplification paths,to generate PAM4 output current signal with levels of 0,40,80,and 120 mA when driving 25-Ωlasers.The high and low amplification paths can be used separately or simultaneously as a 15 Gbps-NRZ LDD.The measurement results show clear output eye diagrams at speeds of up to 15 and 30 Gbps for the NRZ and PAM4 drivers,respectively.At a maximum output current of 120 mA,the driver consumes 1.228 W from a single supply voltage of-5.2 V.The proposed driver shows a high current driving capability with a better output power to power dissipation ratio,which makes it suitable for driving high current distributed feedback(DFB)lasers.The chip occupies a total area of 0.7×1.3 mm^(2). | Ahmed Wahba Lin Cheng Fujiang Lin | 2021 | Journal of Semiconductors2021，42，7： | 2 |
| 5 | Radiotherapy in Non-Functioning Pituitary Macroadenoma: Mansoura Experience显示文摘 | Hanan Ahmed Wahba Hend Ahmed EI-Hadaad Eman Hamza EI-Zahaf Mohammacl ADu-Hegazy | 2011 | Clinical oncology and cancer resexreh2011，8，4： | 2 |
| 6 | Optimal convergence properties of variable knot, kernel, anti orthogonal series methods for density estimation显示文摘 | Wahba G | 1975 | Annals of Statistics1975，3，： | 1 |
| 7 | GPRS Security as a QoS in the Telecommunication Industry Case of Vodafone Egypt显示文摘 | Kamel S Wahba K | 2004 | International Journal of Information Management2004，24，1： | 1 |
| 8 | A least squares estimate of spacecraft attitude显示文摘 | Wahba G | 1965 | Problem 65-1 SIAM Review1965，7，3： | 1 |
| 9 | Autonomic nervous system dysfunction in Parkinson' s disease 显示文摘 | Zesiewicz TA Baker MJ Wahba M el al | 2003 | Curr Treat Options Neurol2003，5，2： | 1 |
| 10 | A note on gen- eralized cross-validation with replicates 显示文摘 | Chong Gu Nancy Heckman Grace Wahba | 1992 | Statistics Probability Letters1992，14，4： | 1 |
| 11 | Generalized cross- validation as a method for choosing a good ridge pa- rameter显示文摘 | Golub G H Heath M Wahba G | 1979 | Technometrics1979，21，2： | 1 |
| 12 | A method for automatic design error location and correction in combinational logic circuits显示文摘 | WAHBA A M BORRIONE D | 1996 | Journal of Electronic Testing:Theory and Applications1996，18，2： | 1 |
| 13 | Support vector machines for classification in nonstandard situations显示文摘 | Lin Y Lee Y Wahba G | 2002 | Machine Learning2002，46，： | 1 |
| 14 | Density,Social Networks and Job Search Methods:Theory and Application to Egypt显示文摘 | Jackline Wahba Yves Zenou | | 0，，11： | 1 |
| 15 | Perioperative functional residual capacity显示文摘 | Wahba RW | 1991 | Can J Anesth1991，38，11： | 1 |
| 16 | Generalized cross validation as a method for choosing a good ridge parameter 显示文摘 | Golub G H Heath M Wahba G | 1979 | Technometrics1979，21，2： | 1 |
| 17 | Smoothing noisy data with spline functions:estimating the correct degree of smoothing by the method of generalized cross-validation 显示文摘 | Craven P Wahba G | 1979 | Numerisehe Mathematik1979，31，： | 1 |
| 18 | Proinflammatorycytokines in Egyptian elderly with chronic obstructive pul-monary disease显示文摘 | Amer MS Wahba HM Ashmawi SS | 2010 | Lung India2010，27，4： | 1 |
| 19 | Smoothing Noisy Data with Spline Functions:Estimating the Correct Degree of Smoothing by the Method of Generalized Cross-Validation显示文摘 | Craven P Wahba G | 1979 | Numerische Mathematik1979，31，： | 1 |
| 20 | Gcvpak-routines for generalized cross validation 显示文摘 | Bates D M Lindstrom M J Wahba G | 1987 | Communications in Statistics-Simulation and Computation1987，16，1： | 1 |
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