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87篇 您的检索式:作者名="WINTER S E"
    题名 作者 年代 出处 被引量
1Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels 2010World Journal of Gastroenterology2010,16,6:11
2Assessing Forest Naturalness显示文摘Mcroberts R E Winter S Chirici G 2012Forest Science2012,58,3:1
3Photochemical generation of nitrenium ions from protonated 1,1- diarylhydrazines 显示文摘Winter A H Thomas S L Falvey D E 2004Org Lett2004,6,25:1
4Adjusting ath- letes~body mass index to better reflect adiposity in epidemio- logical research显示文摘NEVILL A M WINTER E M WATTS A S 2010J Sports Sci2010,28,:1
5Spatial scale, species diversity, and habitat structure: Smallmammals in Australian tropi- cal rain forest显示文摘Williams S E Marsh H Winter J 2002Ecology2002,83,5:1
6Inhibin - B levels in healthy young adult men and prepubertal boys: Is obesity the cause for the contemporary decline in sperm count because of fewer Sertoli cells 显示文摘Winters S J Wang C Abdelrahaman E 2006Androl2006,27,4:1
7Immunoglobulin class response to canine distemper virus in gnotobiotic dogs显示文摘Winters K A Mathes L E Krakowka S 1983Vet Immunol Immunopathol1983,5,2:1
8Gut inflammation provides a respiratory electron acceptor for Salmenella显示文摘WINTER S E THIENNIMITR P WINTER M G 2010Nature2010,467,:1
9Untangling dynamic and operational capabilities: Strategy for the (N) ever-changing world 显示文摘Helfat C E and Winter S G 2011Strategie Management Journal2011,32,11:1
10Prognostic significance of BCL-6 protein expression in DLBCL treated with CHOP or R-CHOP:a prospective correlative study显示文摘Winter J N Weller E A Horning S J 2006Blood2006,107,11:1
11Balance recovery from medio-lateral perturbations of the upper body during standing 显示文摘Rietdyk S Patla A E Winter D A 1999J of Biomechanics1999,32,:1
12Randomized comparation of vinorelbine and melphalan in anthracycline-refractory advanced breast cancer显示文摘Jones S Winter E Vogel C 1995J Clin Oncol1995,13,8:1
13Hospitalized Patients with Novel Influenza A (H1N1) Virus Infection - California, April-May, 2009显示文摘Louie J Winter K Harriman K Vugia D Glaser C Matyas B Schnurr D Guevara H Pan C Y Saguar E Berumen R Hunley E Messenger S Preas C Hatch D Chavez G Kriner P Lopez K Sunega D Rexin D Roach S Kempf J Gonzalez R Morgan L Barnes N Berm 2009MMWR Morbidity and Mortality Weekly Report2009,,19:1
14Antibodies specific for the Hia adhesion proteins of nontypeable Haemophilus influenzae mediate opsonophagocytic activity显示文摘Winter L E Barenkamp S J 2009Clin Vaccine Immunol2009,16,:1
15Recent developments, status and prospects of molluscan aquaculture on the pacific coast of South America显示文摘Winter J E Tom J E Navarro G S 1984Aquaculture1984,39,:1
16Efficient mechanisms for multiple public goods 显示文摘MUTUSWAMI S WINTER E 2004Journal of Public Economics2004,88,34:1
17Antibodies specific for the Hia adhesion proteins of nontypeable Haemophilus influenzae mediate opsonophagocytic activity 显示文摘Winter L E Barenkamp S J 2009Clin Vaccine Immunol2009,16,7:1
18Assessment of balance control in humans 显示文摘Winter D A Patla A E Frank J S 1990Medi Prog Thro Tech1990,16,:1
19Assessment of balance control in humans 显示文摘 Patla A E Frank J S 1990Medi Prog Through Tech1990,16,:1
20The effect of acetate and other short-chain carbon compounds on the kinetics of biological nutrient removal 显示文摘GERBER A MOSTERT E S WINTER C T 1986Water SA1986,12,20:1
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