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| 1 | Neu/c─erbB─2癌基因在颊粘膜上皮良性及恶性病变中的表达及其定量研究显示文摘目的:观察Neu/c-erbB-2癌基因在颊粘膜上皮良性、癌前以及癌变状态下的表达,并确立图像分析系统定量的方法.方法:用三种抗Neu抗体,通过微波暴露抗原,进行标准化的EliteABC染色,并通过半定量及图像分析系统确立Neu基因在不同标本病变中的表达.结果:Neu基因在恶变组有高表达(63.5%),以转移和复发的病变反应强度最高.此外,在癌前病变中也有较高的表达(56.3%).结论:本研究建立的免疫组化定量方法检测Neu基因表达的系统精确、可靠、重复性好,选取的指标可充分反映Neu基因表达的量以及细胞的阳性表达率.结果证实了Neu基因与口腔鳞癌的癌变关系密切,在癌变的早期以及转移和复发的病变中有较高的表达. | 金岩 杨连甲 Tipoe GL Prinz J White FH | 1996 | 第四军医大学学报1996，17，6： | 3 |
| 2 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 3 | Congenital cytomegalovirus infection and brain clefting显示文摘 | White AL Hedlund GL Bale JF Jr | 2014 | Pediatr Neurol2014，50，3： | 1 |
| 4 | Tuberculosis: a health education imperative returns显示文摘 | White GL Henthorne BH Barnes SE | 1995 | J Community Health1995，20，1： | 1 |
| 5 | Eosinophilic fasciitis with pulmonary and pleural involvement显示文摘 | Killen JW Swift GL White RJ | 2000 | Postgrad Med J2000，76，： | 1 |
| 6 | Cardiac tumors :diagnosis and management显示文摘 | Salcedo EE Cohen GL White RD | 1992 | Curr Probl Cardiol1992，17，2： | 1 |
| 7 | Mohs micrographic surger3' 显示文摘 | Bowen GM White GL J ' Gerwels JW | 2005 | AIn Faro Physician2005，72，5： | 1 |
| 8 | Mohs′micrographic surgery显示文摘 | Bowen GM White GL Jr Gerwels JW | 2005 | Am Fam Physician2005，72，5： | 1 |
| 9 | Antihypertensive efficacy of hydrochlorothiazide versus chlorthalidone combined with zzilsar- tan medoxomil显示文摘 | Bakris GL Sica D White WB | 2012 | Am JMed2012，125，12： | 1 |
| 10 | Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice显示文摘 | Chapman PF White GL Jones MW | 1999 | Nat Neurosci1999，2，3： | 1 |
| 11 | New angiotensin II recep- tor blocker azilsartan medoxomil coadministered with ehlorthali- done provides potent blood pressure reduction in stage 2 hyperten-sion显示文摘 | Sica D Bakris GL White WB | 2010 | J Clin Hypertens2010，12，1： | 1 |
| 12 | Relationship between total bilirubin and endothelial function, inflammation and oxidative stress in HIV ‐infected adults on stable antiretroviral therapy显示文摘 | CO Hileman CT Longenecker TL Carman GL Milne DE Labbato NJ Storer CA White GA McComsey | 2012 | HIV Med2012，，10： | 1 |
| 13 | Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice显示文摘 | CHAPMAN PF WHITE GL JONES MW | 1999 | Nat Neurosci1999，2，3： | 1 |
| 14 | Azilsartan medox- omil plus chlorthalidone reduces blood pressure more effectively than olmesartan plus hydrochlorothiazide in stage 2 systolic hyper- tension 显示文摘 | Cushman WC Bakris GL White WB | 2012 | Hypertension2012，60，2： | 1 |
| 15 | Proliferative activity as detected by immunostaining with Ki-67 and proliferating cell nuclear antigen in benign and malignant epithelial lesions of the human parotid gland 显示文摘 | Zhu Q Tipoe GL White FH | 1999 | Anan Quant Cytol Histol1999，21，4： | 1 |
| 16 | Impact of tumor Epstein- Barr virus status on presenting features and outcome in age-defined subgroups of patients with classic Hodgkin lymphoma: a population-based study 显示文摘 | Jarrett RF Stark GL White J | 2005 | Blood2005，106，7： | 1 |
| 17 | Telmisartan/Hydrochlorothiazide : a review of its use as fixed-dose combinations in essntial hypertension 显示文摘 | Plosker GL White WB | 2008 | Drugs2008，68，： | 1 |
| 18 | Restoration of longitudinalforearm stability using a suture button construct显示文摘 | Drake ML Farber GL White KL | 2010 | J Hand SurgAm2010，12，： | 1 |
| 19 | Proliferative activity as detected by immunostaining with Ki67 and proliferating cell nuclear antigen in benign and malignant epithelial lesions of the human parotid gland显示文摘 | Zhu Q Tipoe GL White FH | 1999 | Anal Quant Cytol Histol1999，21，4： | 1 |
| 20 | Hypothermia: threat to military operations显示文摘 | Herr RD White GL | 1991 | Mil Med1991，156，3： | 1 |
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