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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Iatrogenic postatic urethral stric ture:classification and endoscopic treament显示文摘 | Vit P Paolo E | 1999 | Urology1999，53，： | 1 |
| 3 | Red Ceramic Pigments of Terbium-doped Ceria Prepared Through Classical and Non- conventional Coprecipitation Routes显示文摘 | Llusar M Vit/tskovfi L gulcovfi P | 2010 | Journal of the European Ceramic Society2010，30，1： | 1 |
| 4 | Composition of Venezuelan honeys from stingless bees (Apidae:Meliponinae) and Apis mellifera显示文摘 | VIT P BOGDANOV S KILCHENMANN V | 1994 | Apidologie1994，25，： | 1 |
| 5 | Gliopathic pain:when satellite glial cells go bad显示文摘 | Ohara P T Vit J P Bhargava A | 2009 | The Neuroscientist2009，15，5： | 1 |
| 6 | Antioxidant enzymes responses to cadmium in radish tissues显示文摘 | Vitó ria A P Lea P J Azevedo R A | 2001 | Phytochemistry2001，57，： | 1 |
| 7 | Tissue factor, its inhibitor, and the thrombogenicity of two new synthetic membranes 显示文摘 | Zemanova P Opatrny K Vit L | 2005 | Artif Organs2005，29，8： | 1 |
| 8 | Antioxidant enzymes responses to cadmium in radish tissues显示文摘 | Vitória Angela P Peter J Lea | 2001 | Phytochemistry2001，57，5： | 1 |
| 9 | Cortical modulation of pain显示文摘 | Ohara P T Vit J P Jasmin L | 2005 | Cell Mol Life Sci2005，62，1： | 1 |
| 10 | Is robotic surgery appropriate for vascular procedures? Report of 100 aortoiliac cases显示文摘 | Stádler P Dvorácek L Vitásek P | 2008 | Eur J Vasc Endovasc Surg2008，36，4： | 1 |
| 11 | Kupffer cell-generated PGE2 triggers the febrile response of guinea pigs to intravenously injected LPS 显示文摘 | LI Zhong-hua Vit P Carlos F | 2006 | Am J Physiol Regul Integr Comp Physiol2006，290，5： | 1 |
| 12 | The role of dehydrins in plant response to cold显示文摘 | KosováK Vitámvás P Práil I T | 2007 | Biologia Plantarum2007，51，4： | 1 |
| 13 | A fast quartet tree heuristicfor hierarchical clustering显示文摘 | Cilibrasi R L Vitányi P MB | 2011 | Pattern Recognition2011，44，3： | 1 |
| 14 | Role of thyroid ultrasound in the diag- nost icevaluation of thyroid nodules显示文摘 | Rago T Vit ti P | 2008 | Best Pract Res Clin Endocrinol Metab2008，22，6： | 1 |
| 15 | Tissue factor, its inhibitor, and the thrombogenicity of two new synthetic membranes显示文摘 | Zemanova P Opatrny K Vit L | 2005 | Artif Organs2005，29，： | 1 |
| 16 | Effect of cadmium on antioxidant enzyme activities in sugar cane显示文摘 | Fomazier R F Ferreira R R Vitória A P | 2002 | Biologia Plantarum2002，45，1： | 1 |
| 17 | Andrei Nikolaevich Kolmogrov显示文摘 | Vitànyi P M B | 1998 | CWI Quarterly1998，，1： | 1 |
| 18 | Hepatic pufine enzymes and uric acid excretion as indictors of protein quality in chicks fed graded L-lysine diets显示文摘 | VIT P CIOCCIA A M BRITO O | 1993 | Journal of the Science of Food and Agriculture1993，62，4： | 1 |
| 19 | Volatile attractants from ponderosa pine attacked by bark beetles 显示文摘 | Vit e J P Gara R I | 1962 | Contrib Boyce Thompson Inst1962，21，5： | 1 |
| 20 | Pathophysiological and Clinical approach to cirrhotic cardiomyopathy显示文摘 | Páll A Czifra A Vitális Z | 2014 | J Gastrointestin Liver Dis2014，23，3： | 1 |
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