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| 1 | Evidence to suggest adoption of water exchange deservesbroader consideration:Its pain alleviating impact occurs in90%of investigators显示文摘AIM: To determine variations in colonoscopy real-time insertion pain among investigators using three different insertion techniques.METHODS: From March 2013 through June 2014, 18-85-year-old diagnostic and 50-70-year-old screening patients were enrolled at each center to on-demand sedation colonoscopy with water exchange(WE), water immersion(WI) and insufflation with air or CO2 for insertion and withdrawal [air or carbon dioxide(AICD)]. Data were aggregated for analysis. Primary outcome: Variations in real-time maximum insertion pain(0 = none, 1-2 = discomfort, 10 = worst).RESULTS: One thousand and ninety-one cases analyzed: WE(n = 371); WI(n = 338); AICD(n = 382). Demographics and indications were comparable. The WE group had the lowest real-time maximum insertion pain score, mean(95%CI): WE 2.8(2.6-3.0), WI 3.8(3.5-4.1) and AICD 4.4(4.1-4.7), P < 0.0005. Ninety percent of the colonoscopists were able to use water exchange to significantly decrease maximum insertion pain scores. One investigator had high insertion pain in all groups, nonetheless WE achieved the lowest real-time maximum insertion pain score. WE had the highest proportions of patients with painless unsedated colonoscopy(vs WI, P = 0.013; vs AICD, P < 0.0005); unsedated colonoscopy with only minor discomfort(vs AICD, P < 0.0005), and completion without sedation(vs AICD, P < 0.0005).CONCLUSION: Aggregate data confirm superiority of WE in lowering colonoscopy real-time maximum insertion pain and need for sedation. Ninety percent of investigators were able to use water exchange to significantly decrease maximum insertion pain scores. Our results suggest that the technique deserves consideration in a broader scale. | Sergio Cadoni Mauro Liggi Premysl Falt Stefano Sanna Mariangela Argiolas Viviana Fanari Paolo Gallittu Donatella Mura Maria L Porcedda Vit Smajstrla Matteo Erriu Felix W Leung | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 2 |
| 2 | Low-level laser therapy enhances the number of osteocytes in calvaria bone defects of ovariectomized rats显示文摘Background : Osteoporosis can make bone repair difficult. Low-level laser therapy( LLLT) has been shown to be a promising tool for bone neoformation. This study aimed to analyze the effect of LLLT on calvaria bone defects of ovariectomized rats using stereology. Methods : Fifty-four Wistar rats were subjected to bilateral ovariectomy, and bone defects were created in calvaria after 150 days. The animals were divided into nine groups(n = ?6 per group), and 24 hours after the bone defects were created they received three, six or 12 sessions of LLLT at 0, 20 or 30 J/cm 2, using a 780-nm low-intensity GaAlAs laser. One-way ANOVA followed by Tukey ' s post hoc test was used for data processing. A difference of P < 0.05 was considered statistically significant. The parameters evaluated were osteocyte density( Nv_(ost)), total osteocyte number( Nto ost), trabecular surface density( Sv_t), and trabecular surface area( Sa_t). Results : Data obtained showed that Nto ost, Sv t, and Sa t in group G2 rats were significantly different from G1(0 J/cm^2)( P < 0.05). Compared to group G4, G5 presented higher values for the parameters Sv t and Sa t, and G6 presented significantly higher values for almost all the analyzed parameters( Nv _(ost), Nto_(ost), Sv_t, and Sa t)( P < 0.05). Compared to group G7, G8 showed a higher value only for the parameter Sa t, and G9 showed significantly higher values for parameters Nv ost, Nto ost, Sv_t, and Sa_t. Conclusion : We conclude that LLLT stimulated bone neoformation and contributed to an increase in the total number of osteocytes, especially with a laser energy density of 30 J/cm^2 given for six and 12 sessions. | Priscilla Hakime Scalize Luiz Gustavo de Sousa Lígia Maria Napolitano Goncalves Dimitrius Leonardo Pitol Marcelo Palinkas Antonio Augusto Coppi Mariah Acioli Righeti Vitória Ricardo Karina Fittipaldi Bombonato-Prado Simone Cecílio Hallak Regalo Selma Siessere | 2019 | Animal Models and Experimental Medicine2019，2，1： | 2 |
| 3 | Soil mineral nitrogen availability was unaffected by elevated atmospheric pCO2 in a four-year-old field experiment(Swiss FACE)显示文摘 | Vit G Matra J Andreas L | 2000 | Plant and Soil2000，227，： | 1 |
| 4 | Effect of support on the synergy in HDS of thiophene and of pyridine over sulfide catalysts promoted by RH 显示文摘 | VIT Z GULKOVA D KALUZA L | 2004 | Reaetion Kinetics and Catalysis Letters2004，83，2： | 1 |
| 5 | Red Ceramic Pigments of Terbium-doped Ceria Prepared Through Classical and Non- conventional Coprecipitation Routes显示文摘 | Llusar M Vit/tskovfi L gulcovfi P | 2010 | Journal of the European Ceramic Society2010，30，1： | 1 |
| 6 | The full mutation in the FMR - 1 gene of male fragile X patients is absent in their sperm 显示文摘 | Reyniers E Vits L De BK | 1993 | Nat Genet1993，4，2： | 1 |
| 7 | Tissue factor, its inhibitor, and the thrombogenicity of two new synthetic membranes 显示文摘 | Zemanova P Opatrny K Vit L | 2005 | Artif Organs2005，29，8： | 1 |
| 8 | A fast quartet tree heuristic for hierarchical clustering 显示文摘 | Rudi L Cilibrasi Paul M B Vit&nyi | 2011 | Pattern Recognition2011，44，3： | 1 |
| 9 | Satellite glial cells in the trigeminal ganglion as a determinant of orofacial neuro- pathic pain显示文摘 | Vit JP Jasmin L Bhargava A | 2006 | Neuron Gila Biol2006，2，4： | 1 |
| 10 | Cortical modulation of pain显示文摘 | Ohara P T Vit J P Jasmin L | 2005 | Cell Mol Life Sci2005，62，1： | 1 |
| 11 | Is robotic surgery appropriate for vascular procedures? Report of 100 aortoiliac cases显示文摘 | Stádler P Dvorácek L Vitásek P | 2008 | Eur J Vasc Endovasc Surg2008，36，4： | 1 |
| 12 | A fast quartet tree heuristicfor hierarchical clustering显示文摘 | Cilibrasi R L Vitányi P MB | 2011 | Pattern Recognition2011，44，3： | 1 |
| 13 | Tissue factor, its inhibitor, and the thrombogenicity of two new synthetic membranes显示文摘 | Zemanova P Opatrny K Vit L | 2005 | Artif Organs2005，29，： | 1 |
| 14 | Populatio and biomas kinetics in fed-Batch cultures of daucus carota L somatic embryos显示文摘 | Huang L C Chi C M Vits H | 1993 | Biotechnol Bioeng1993，41，： | 1 |
| 15 | Can satellite glial cells be thera- peutic targets for pain control显示文摘 | Jasmin L Vit JP Bhargava A | 2010 | Neuron Glia Biol2010，6，1： | 1 |
| 16 | L1-associated diseases:clinical geneticists divide,molecular geneticists unite显示文摘 | Fransen E van Camp G Vits L | 1997 | Hum Mol Genet1997，6，10： | 1 |
| 17 | Ivan S显示文摘 | Vit L | | 0，，： | 1 |
| 18 | Effect of support type on the magnitude of synergism and promotion in CoMo sulphide hydrodesulphurisation catalyst 显示文摘 | Kaluza L Gulkova D Vit Z | 2007 | Applied Catalysis A General2007，324，： | 1 |
| 19 | What are the factors contributing to the changes in tissue-type plasminogen activator during haemodialysis? 显示文摘 | OPATRNY K J R VIT L OPATRNY S | 1991 | Nephrol Dial Transplant1991，6，3： | 1 |
| 20 | The Google similarity distance显示文摘 | Cilibrasi R L Vitányi P M | 2007 | IEEE Transactions on Knowledge and Data Engineering2007，19，3： | 1 |
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