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12篇 您的检索式:作者名="Visith"
    题名 作者 年代 出处 被引量
1Serum proteins in chronic hepatitis B patients treated with peginterferon alfa-2b显示文摘AIM: To study the differential protein profile in serum of hepatitis B patients.METHODS: Serum samples were obtained from patients with chronic hepatitis B who were receiving peginterferon alfa-2b.The serum samples were subjected to albumin depletion and analyzed by two-dimensional gel electrophoresis(2-DE).Differentially expressed protein spots were identified by electrospray ionizationquadrupole time-of-flight mass spectrometry.Alpha2-HS-glycoprotein,complement component C3c and CD5 antigen were further analyzed by an enzymelinked immunosorbent assay and immunonephelometry.RESULTS: Nineteen patients with HBeAg-positive chronic hepatitis B(CHB) were studied.These patients were followed for at least 1 year after treatment and were classified according to their treatment response: responders(n = 9) and non-responders(n = 10).2-DE and MS/MS analysis were performed to compare the serum proteins before initiating peginterferon alfa2b.From the quantitative analysis of the 2-D gel,7 proteins were detected between the two groups at different levels before treatment.Among these potential candidates,serum levels of alpha-2-HS-glycoprotein,complement component C3c and CD5 antigen-like precursor were further analyzed.In the validation phase,23 subjects,9 sustained responders and 14 nonresponders,were recruited.Interestingly,the levels of alpha-2-HS-glycoprotein and complement component C3c were elevated in the serum of the non-responders compared to the responders.CONCLUSION: Serum alpha-2-HS-glycoprotein and complement component C3c may be potential serum biomarkers in predicting the treatment response of peginterferon alfa-2b in patients with CHB prior to treatment.Sunida Kuakarn Poorichaya SomParn Pisit Tangkijvanich Varocha Mahachai Visith Thongboonkerd Nattiya Hirankarn 2013World Journal of Gastroenterology2013,19,31:4
2Identification of human hnRNP C1/C2 as a dengue virus NS1-interacting protein显示文摘Sansanee Noisakran Suchada Sengsai Visith Thongboonkerd Rattiyaporn Kanlaya Supachok Sinchaikul Shui-Tein Chen Chunya Puttikhunt Watchara Kasinrerk Thawornchai Limjindaporn Wiyada Wongwiwat Prida Malasit Pa-thai Yenchitsomanus 2008Biochemical and Biophysical Research Communications2008,,1:2
3Systematic comparisons of artificial urine formulas for in vitro cellular study显示文摘Somchai Chutipongtanate Visith Thongboonkerd 2010Analytical Biochemistry2010,,1:1
4Animal toxins: an overview 显示文摘Visith Sitprija Suchai Suteparak 2008Asian Biomedicine2008,12,2:1
5Proteomic identification of a novel protein regulated in CA1 and CA3 hippocampal regions during intermittent hypoxia显示文摘Jon B K David G William M P Visith T Janice A S Leroy R S Shang Z G Jian C Evelyne G 2003Respir Physiol Neurobiol2003,136,:1
6Fluoride exposure attenuates expression of streptococcus pyogenes virulence factors 显示文摘Visith T Jirapon L Junkai C 2002J Biol Chem2002,277,16:1
7Proteomics in extracorporeal blood purification and peritoneal dialysis显示文摘Visith Thongboonkerd 2009Journal of Proteomics2009,1,3:1
8Fluoride exposure attenuates expression of streptococcus pyogenes virulence factors显示文摘Visith TH Jirapon L Junkai C 2002J Biolog Chem2002,277,16:1
9Animal toxins: an overview 显示文摘Visith Sitprija Suchai Suteparak 2008Asian Biomedicine2008,12,2:1
10Dipeptidyl Peptidase 4 Inhibition Increases Myocardial Glucose Uptake in Nonischemic Cardiomyopathy显示文摘Ronald M. Witteles Khun Visith Keu Andrew Quon Homa Tavana Michael B. Fowler 2012Journal of Cardiac Failure2012,,10:1
11Renal effects and injury induced by animal toxins显示文摘Visith Sitprija Siravit Sitprija 2012Toxicon2012,,5:1
12Ceftriaxone crystallization and its potential role in kidney stone formation显示文摘Somchai C Visith T 0,,3:1
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