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| 1 | 牧草如何生长——植物生长与放牧管理之关联(英文)显示文摘适当管理饲料饲草资源的基本原则是理解多年生牧草如何生长。长期以来 ,对根系生长有了基本的了解 ,对去叶和环境对根系生长的影响也知之甚多。然而 ,对去叶、干旱及其他环境因素对多年生牧草的影响以及这些牧草对去叶的反应缺乏应有的理解。从牧草返青到开花 ,植物处于短枝阶段 ,适度放牧并不对多年生牧草的健康和活力造成危害 ,因为植物会弥补其失去的叶片。然而 ,当牧草从短枝向长枝阶段 (节间伸长和开花期 )转移时 ,碳水化合物主要用于节间伸长和开花过程。在开花后和休眠前期 ,碳水化合物主要向茎基和植物基部转移 ,以供来年新枝条的发育。因此 ,在花后和休眠前期 ,放牧系统必须被调节到“无放牧”状态。“无放牧”状态 ,如休息、轮牧、延迟轮牧和快速轮牧制 ,其价值在于这种定期的禁牧可提高多年生牧草的活力 ,改善草地的健康状况 ,并且在不利的环境条件下 。 | Ronald E Sosebee David B Wester J Carlos Villalobos Carlton M Britton Changgui Wan Hisham Nofal | 2005 | 草业学报2005，14，1： | 8 |
| 2 | Endoscopic submucosal dissection in dogs in a World Gastroenterology Organisation training center显示文摘AIM: To evaluate if canine models are appropriate for teaching endoscopy fellows the techniques of endoscopic submucosal dissection (ESD). METHODS: ESD was performed in 10 canine models under general anesthesia, on artificial lesions of the esophagus or stomach marked with coagulation points. After ESD, each canine model was euthanized and surgical resection of the esophagus or stomach was carried out according to 'The Principles of Humane Experimental Technique, Russel and Burch'. The ESD specimens were fixed with needles on cork submerged in a formol solution with the esophagus or stomach, and delivered to the pathology department to be analyzed. RESULTS: ESD was completed without complications using the Hook-knife in five esophageal areas, with a procedural duration of 124 ± 19 min, a length of 27.4 ± 2.6 mm and a width of 21 ± 2.4 mm. ESD was also completed without complications using the IT-knife2 in five gastric areas, with a procedural duration of 92.6 ± 19 min, a length of 32 ± 2.5 mm and a width of 18 ± 3.7 mm. CONCLUSION: ESD is feasible in the normal esopha- gus and stomach of canine models, which are appropriate for teaching this technique. | Miguel A Tanimoto Gonzalo Torres-Villalobos Rikiya Fujita Patricio Santillan-Doherty Jorge Albores-Saavedra German Gutierrez Luis A Martin-del-Campo Carlos Bravo-Reyna Octavio Villanueva Jose J Villalobos Misael Uribe Miguel A Valdovinos | 2010 | World Journal of Gastroenterology2010，16，14： | 7 |
| 3 | Is it possible to stop nucleos(t)ide analogue treatment in chronic hepatitis B patients?显示文摘Chronic hepatitis B(CHB) remains a challenging global health problem, with nearly one million related deaths per year. Nucleos(t)ide analogue(NA) treatment suppresses viral replication but does not provide complete cure of the hepatitis B virus(HBV) infection. The accepted endpoint for therapy is the loss of hepatitis B surface antigen(HBs Ag), but this is hardly ever achieved. Therefore, indefinite treatment is usually required. Many different studies have evaluated NA therapy discontinuation after several years of NA treatment and before HBs Ag loss. The results have indicated that the majority of patients can remain off therapy, with some even reaching HBs Ag seroconversion. Fortunately, this strategy has proved to be safe, but it is essential to consider the risk of liver damage and other comorbidities and to ensure aclose follow-up of the candidates before considering this strategy. Unanswered questions remain, namely in which patients could this strategy be effective and what is the optimal time point at which to perform it. To solve this enigma, we should keep in mind that the outcome will ultimately depend on the equilibrium between HBV and the host's immune system. Viral parameters that have been described as good predictors of response in HBe Ag(+) cases, have proven useless in HBe Ag(-) ones. Since antiviral immunity plays an essential role in the control of HBV infection, we sought to review and explain potential immunological biomarkers to predict safe NA discontinuation in both groups. | Elia Moreno-Cubero Robert T Sánchez del Arco Julia Pena-Asensio Eduardo Sanz de Villalobos Joaquín Míquel Juan Ramón Larrubia | 2018 | World Journal of Gastroenterology2018，24，17： | 5 |
| 4 | Persistent hepatitis C virus (HCV) infection impairs HCV‐specific cytotoxic T cell reactivity through Mcl‐1/Bim imbalance due to CD127 down‐regulation显示文摘 | J. R. Larrubia M. U. Lokhande S. García‐Garzón J. Miquel A. González‐Praetorius T. Parra‐Cid E. Sanz‐de‐Villalobos | 2012 | Journal of Viral Hepatitis2012，，2： | 3 |
| 5 | Micropropagation of 21 species of Moxican cacti by axillary proliferation显示文摘 | Perez M B Perez E Villalobos A M E | 1998 | In Vitro Cellular & Developmental Biology Plant1998，34，2： | 2 |
| 6 | Modeling root growth and the soil–plant–atmosphere continuum of cotton crops显示文摘 | M.B. Coelho F.J. Villalobos L. Mateos | 2002 | Agricultural Water Management2002，，2： | 2 |
| 7 | Nitro-PAH exposures of occupationally-exposed traffic workers and associated urinary 1-nitropyrene metabolite concentrations显示文摘The assessment of occupational exposure to diesel exhaust(DE) is important from an epidemiological perspective. Urinary biomarkers of exposure have been proposed as a novel approach for measuring exposure to DE. In this study, we measured the concentrations of two urinary metabolites of 1-nitropyrene(1NP), a nitrated polycyclic aromatic hydrocarbon that has been suggested as a molecular marker of diesel particulate matter. These two metabolites, 6-hydroxy-1-nitropyrene and 8-hydroxy-1-nitropyrene, were determined in urine samples(10 m L) from a small group of workers who were occupationally-exposed to vehicle exhaust in Trujillo, Peru, before and after their workshifts. Workshift exposures to1 NP, as well as PM_(2.5), 2-nitropyrene and 2-nitrofluoranthene, were also measured.Exposures to 1NP were similar in all studied workers, averaging 105 ± 57.9 pg/m^3(±standard deviation). Median urinary concentrations of the average of the pre- and post-exposure samples for 6-hydroxy-1-nitropyrene and 8-hydroxy-1-nitropyrene, were found to be 3.9 and 2.3 pg metabolite/mg creatinine, respectively in the group of occupationally-exposed subjects(n = 17) studied. A direct relationship between workshift exposure to 1NP and urinary 1NP metabolites concentrations was not observed. However,the 1NP exposures and the creatinine-corrected urinary concentrations of the hydroxynitropyrene metabolites in these Peruvian traffic workers were similar to occupationally-exposed taxi drivers in Shenyang, China, and were higher than biomarker levels in office workers from Trujillo without occupational exposure to vehicle exhaust.This study provides further evidence that urinary metabolites of 1NP are associated with exposure to DE and may serve as a useful exposure biomarker. | Justin P.Miller-Schulze Michael Paulsen Takayuki Kameda Akira Toriba Kazuichi Hayakawa Brandon Cassidy Luke Naeher Manuel Aguilar Villalobos Christopher D.Simpson | 2016 | Journal of Environmental Sciences2016，28，11： | 2 |
| 8 | Modeling no-notice mass evacuation using a dynamic traffic flow optimization model显示文摘 | Chiu Y Zheng H Villalobos J | 2007 | IIE Transactions2007，39，1： | 1 |
| 9 | Spatially resolved characterization of biogenic manganese oxide production within a bacterial biofilm显示文摘 | Toner B Fakra S Villalobos M | 2005 | Applied and Environmental Microbiology2005，71，3： | 1 |
| 10 | Th1 and Th2 indices of the immune response in pigs vaccinated against Taenia soiium cysticercosis suggest various host immune strategies against the parasite 显示文摘 | Dfaz MA Villalobos N de Aluja A | 2003 | Vet Immunol Immunopathol2003，93，34： | 1 |
| 11 | Depth of water uptake in woody plants relates to groundwa-ter 1eve|l and vegetation structure along a topographic gra- dient in a neotropical savanna 显示文摘 | Rossatto D R Silva L C R Villalobos - Vega R | 2012 | Environmental and Ex- perimental Botany2012，77，： | 1 |
| 12 | Carbon exchange and water use efficiency of a growing, irrigated olive orchard显示文摘 | Luca Testi Francisco Orgaz Francisco Villalobos | 2007 | Environmental and Experimental Botany2007，63，： | 1 |
| 13 | Visinin-like neuronal calcium sensor proteins regulate the slow calcium-activated after-hyperpolarizing current in the rat cerebral cortex显示文摘 | Villalobos C Andrade R | 2010 | Neurosci2010，30，14： | 1 |
| 14 | Genetics of residual energy intake in Irish grazing dairy cows 显示文摘 | Lopez- Villalobos N Berry D P Horan B | 2008 | Proc N Z Soc Anita Prod2008，68，： | 1 |
| 15 | Ex situ conservation of plant germplasm using biotechnology显示文摘 | Villalobos V M Exgelman F | 1995 | Biotechol1995，11，4： | 1 |
| 16 | Transparent ceramics for high-energy laser systems显示文摘 | Jas Sanghera Shyam Bayya Guillermo Villalobos | 2010 | Optical Materials2010，33，2011： | 1 |
| 17 | Clinical use of the optical digitizer for intracranial neuronavigation显示文摘 | Germano IM Villalobos H Silvers A | 1999 | Neuro surgery1999，45，2： | 1 |
| 18 | Prospective e- valuation of imipenem/EDTA combined disc and Etest for detection of metallo - beta - lactamase - producing Pseudomonas aeruginosa 显示文摘 | Berges L Rodriguez - Villalobos H Deplano A | 2007 | Antimicrob Chemother2007，59，4： | 1 |
| 19 | Recurrence and survival rates among early breast cancer cases with triple negative immunophenotype显示文摘 | GERSON R ALBAN F VILLALOBOS A | 2008 | Gac Med Mex2008，144，1： | 1 |
| 20 | Water requirements of olive orehards-I:simulation of daily evapotranspiration for scenario analysis 显示文摘 | Testi L Villalobos F J Orgaz F | 2006 | Irrigation Science2006，24，： | 1 |
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