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| 1 | Thinking in three's: Changing surgical patient safety practices in the complex modern operating room显示文摘The three surgical patient safety events, wrong site surgery, retained surgical items (RSI) and surgical fires are rare occurrences and thus their effects on the complex modern operating room (OR) are difficult to study. The likelihood of occurrence and the magnitude of risk for each of these surgical safety events are undefined. Many providers may never have a personal experience with one of these events and training and education on these topics are sparse. These circumstances lead to faulty thinking that a provider won't ever have an event or if one does occur the provider will intuitively know what to do. Surgeons are not preoccupied with failure and tend to usually consider good outcomes, which leads them to ignore or diminish the importance of implementing and following simple safety practices. These circumstances contribute to the persistent low level occurrence of these three events and to the difficulty in generating sufficient interest to resource solutions. Individual facilities rarely have the time or talent to understand these events and develop lasting solutions. More often than not, even the most well meaning internal review results in a new line to a policy and some rigorous enforcement mandate. This approach routinely fails and is another reason why these problems are so persistent. Vigilance actions alone havebeen unsuccessful so hospitals now have to take a systematic approach to implementing safer processes and providing the resources for surgeons and other stake-holders to optimize the OR environment. This article discusses standardized processes of care for mitigation of injury or outright prevention of wrong site surgery, RSI and surgical fires in an action-oriented framework illustrating the strategic elements important in each event and focusing on the responsibilities for each of the three major OR agents-anesthesiologists, surgeons and nurses. A Surgical Patient Safety Checklist is discussed that incorporates the necessary elements to bring these team members together and influence the emergence of a safer OR. | Verna C Gibbs | 2012 | World Journal of Gastroenterology2012，18，46： | 9 |
| 2 | Telaprevir- and Boceprevir-based Triple Therapy for Hepatitis C in Liver Transplant Recipients With Advanced Recurrent Disease: A Multicenter Study显示文摘 | Elizabeth C. Verna Varun Saxena James R. Burton Jacqueline G. O’Leary Jennifer L. Dodge Richard T. Stravitz Josh Levitsky James F. Trotter Gregory T. Everson Robert S. Brown Norah A. Terrault | 2015 | Transplantation2015，，8： | 2 |
| 3 | Appropriateness of colonoscopy: Diagnostic yield and safety in guidelines显示文摘AIM: To evaluate if the guidelines for the appro-priateness of performing colonoscopy by American Society for Gastrointestinal Endoscopy (AGSE) and Italian Society of Digestive Endoscopy (SIED) yield a good diagnostic efficacy and do not present risks of missing important colonic pathologies in an Italian population sample.METHODS: A total of 1017 consecutive patients (560 men and 457 women; mean age 64.4 ± 16 years) referred to an open-access endoscopy unit for colonoscopy from July 2004 to May 2006 were evaluated according to ASGE and SIED guidelines for appropriateness of performing the procedure. Diagnostic yield was defined as the percentage of relevant colonic pathologies of the total number of colonoscopies performed.RESULTS: About 85.2% patients underwent colono-scopy that was considered appropriate based on at least one ASGE or SIED criterion, while it was considered inappropriate for 14.8% of patients. The diagnostic yield of colonoscopy was significantly higher for appropriate colonoscopies (26.94% vs 10.6%, P < 0.001) than for inappropriate colonoscopies (5.3%). There was no missed colorectal cancer following the ASGE/SIED criteria.CONCLUSION: ASGE/SIED guidelines have shown a good diagnostic yield and the rate of missing relevant colonic pathologies seems very low. Unfortunately, the percentage of inappropriate referrals for colonoscopy in an open-access endoscopy system is still high, despite the number of papers published on the issue and the definition of international guidelines. Further steps are required to update and standardize the guidelines to increase their diffusion and to promote educational programs for general practitioners. | Mario Grassini Carlo Verna Paolo Niola Monica Navino Edda Battaglia Gabrio Bassotti | 2007 | World Journal of Gastroenterology2007，13，12： | 2 |
| 4 | The Hepatitis Aggressiveness Score (HAS): A Novel Classification System for Post–Liver Transplantation Recurrent Hepatitis C显示文摘 | Roger K. Moreira Marcela Salomao Elizabeth C. Verna Robert S. Brown Jay H. Lefkowitch | 2013 | The American Journal of Surgical Pathology2013，，1： | 2 |
| 5 | Hyperglycemia potentiates the proatherogenic effects of C-reactive protein:reversal with rosiglitazone 显示文摘 | Verna s Li S H Wang C H | 2003 | J Mol Cell Cardiol2003，35，4： | 1 |
| 6 | 6-Hydroxydopamine-induced nuclear factor-kappa B activation in PC12 cells显示文摘 | Blum D Torch S Nissou MF Verna JM | 2001 | Biochem Pharmacol2001，62，4： | 1 |
| 7 | Hydrogen peroxide plays a critical role in the defence response of tomato to Cladosporium fulvum显示文摘 | Stephanie B Verna J H | 2002 | Physiological and Molecular Plant Pathology2002，6，： | 1 |
| 8 | Guidelines for success in placement of orthodontic mini-implants显示文摘 | Luzi C Verna C Melsen B | 2009 | J Clin Orthod2009，43，1： | 1 |
| 9 | Immediate loading of orthodontic miniimplants: a histomorphometric evaluation of tissue reaction 显示文摘 | Lazi C Verna C Melsen B | 2009 | Eur J Orthod2009，31，1： | 1 |
| 10 | Patient age and bio- logical aggressiveness of endometrial carcinoma 显示文摘 | Gonzalez-Rodilla 1 Boix M Verna V | 2012 | Antieaneer Res2012，32，5： | 1 |
| 11 | Immediate loading of orthodontic mini-implants: a histomorphometric evaluation of tissue reaction 显示文摘 | Luzi C Verna C Melsen B | 2009 | Eur J Orthod2009，31，1： | 1 |
| 12 | The rate and the type of orthodontic tooth movement is influenced by bone turnover in a rat model 显示文摘 | Verna C Dalstra M Melsen B | 2000 | Eur J Orthod2000，22，4： | 1 |
| 13 | 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation显示文摘 | VERNA L WHYSNER J WILLIAMS G M | 1996 | Pharmacol Ther1996，71，12： | 1 |
| 14 | Expression of the apoptosis-related genes Bcl-2 and P53 in clinical samDles from endometrial carcinoma patients显示文摘 | Gonzdlez-Rodillai Verna V Muoz AB | 2011 | Anticancer Res2011，31，2： | 1 |
| 15 | Constitution activation of peroxisome proliferator-activated receptor-γ suppress pro-inflammatory adhension molecules in human vascular endithelial cells显示文摘 | Verna L Chen NG | 2002 | J Biol Chem2002，277，34： | 1 |
| 16 | Formaldehyde mechanistic data and risk assessment:endogenous protection from DNA adduct formation显示文摘 | Conaway CC Whysner J Verna LK et M | 1996 | Pharmacol Ther1996，71，： | 1 |
| 17 | Development of simu- lation model of the Canary islands for strategic deciong making显示文摘 | Kljajic M Verna C A L Skraba A | 2005 | Organizacija2005，38，9： | 1 |
| 18 | Tissue reaction to orthodontic tooth movement in acute and chronic corticosteroid treatment 显示文摘 | Kalia S Melsen B Verna C | 2004 | Orthod Craniofac Res2004，7，1： | 1 |
| 19 | Miniscrew implants: The Aarhus anchorage system显示文摘 | Melsen B Verna C | 2005 | Semin Orthod2005，11，1： | 1 |
| 20 | Formaldehyde mechanistic data and risk assessment: endogenous protection from DNA adduct formation显示文摘 | Conaway CC Whysner J Verna LK | 1996 | Pharmacol Ther1996，71，12： | 1 |
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