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255篇 您的检索式:作者名="Vanderschueren"
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1【特刊综述】骨骼两性异形中的雄激素和雌激素显示文摘骨骼是表达雄激素、雌激素受体以及类固醇代谢酶的一种内分泌组织。循环性激素的生物活性通过六种性激素结合球蛋白以及在骨组织中的局部转变来进行调节,例如,睾酮通过芳香酶转变成雌二醇,或通过5α还原酶转变成双氢睾酮。由于高分辨外周CT应用的增多,我们对造成骨骼强度性别差异的结构基础的认识在近几年有很大进步。这些对微小结构的观察是理解性激素对男性峰值骨量及对骨皮质和骨小梁之间转变的影响的基础。最近的研究利用Cre/LoxP技术使我们在整体基因敲除小鼠上机械的认识精确到性激素及其在成骨细胞、破骨细胞、骨细胞以及其它造成男性骨质疏松的细胞上的核受体的直接作用。同时,这些研究加强了这样的观点:雄激素和雌激素的缺乏通过与例如胰岛素样生长因子1、炎症、氧化应激、骨骼代谢的中枢神经系统控制、机械负荷的适应等的交互作用发挥直接和多种效应。这篇综述将总结性激素在男性骨骼自身平衡作用这个领域有关方面最近的进展。Michael Laurent Leen Antonio Mieke Sinnesael Vanessa Dubois Evelien Gielen Frank Classens Dirk Vanderschueren 2014Asian Journal of Andrology2014,16,2:4
2Aromatization of androgen is impotant for skeletal maintenance of aged male rats显示文摘Vanderschueren D Van Herk E De Coster R 1996Calcif Tissue Int1996,59,3:1
3Sex steroid actions in male bone显示文摘VANDERSCHUEREN D LAURENT M R CLAESSENS F 2014Endocr Rev2014,35,:1
4Aromatase inhibition impairs skeletal modeling and decreases bone mineral density in growing male rats显示文摘Vanderschueren D van Herck E Nijs J 1997Endocrinology1997,138,6:1
5Inflammation of unknown origin versus fever of unknown origin:two of a kind显示文摘Vanderschueren S Del Biondo E Ruttens D 0,,04:1
6From prolonged febrile illness to fever of unknown origin; the challenge continues 显示文摘Vanderschueren S Knockaert D Adriaenssens T etal 2003Areh Intem Med2003,163,9:1
7Thrombocytopenia and prognosis in intensive care 显示文摘Vanderschueren S De Weerdt A Malbrain M 2000Crit Care Med2000,28,6:1
8Throm- eytopenia and prognosis in intensive eare显示文摘Vanderschueren S Weerdt A Malbrain M 2000Crit Care Med2000,28,2:1
9A randomized trial of recombinant staphylokinase versus alteplase for coronary artery patency in acute myocardial infarction显示文摘Vanderschueren S Barrios L Kerdsinchai P 1995Circulation1995,92,8:1
10Overview of resistance to systemic therapy in patients with breast cancer显示文摘Callewaert PR Van Poppel H Vanderschueren D 0,,9:1
11Randomized coronary potency trial of double-bolus recombinant staphylokinase versus front-loaded alteplase in acute myocardial infarction显示文摘Vanderschueren S Dens J Kerdsinchia P 1997Am Heart J1997,134,2:1
12Thrombocytopenia and prognosis in intensive care显示文摘Vanderschueren S De Weerdt A Malbrain M 2000Crit Care Med2000,28,6:1
13Ejaculation latency times and their relationship to penile sensitivity in men with normal sexual function 显示文摘Vanden Broucke H Everaert K Peersman W Claes H Vanderschueren D Van Kampen M 2007J Urol2007,177,:1
14Thrombocytopenia and prognosis in intensive care显示文摘Vanderschueren S Weerdt A Malbrain M 2000Care Med2000,28,:1
15Outcome of patientsrequiring valve surgery during active infective endocarditis显示文摘Hill EE Herregods MC Vanderschueren S 2008AnnThorao Surg2008,85,5:1
16Active vitamin D ( 1,25 - dihydroxyvitamin D) and bone health in middle - aged and elderly men: the European Male Aging Study (EMAS)显示文摘Vanderschueren D Pye SR O'Neill TW 2013J Clin Endocrinol Metab2013,98,3:1
17Recentdevelopments in the management of postmenopausal osteoporosiswith bisphosphonates : enhanced efficacy by enhanced compliance显示文摘Boonen S Vanderschueren D Venken K 2008J Intern Med2008,264,4:1
18ReerystaUization of Ti IF steel investigated with electron backseat- tering pattern (EBSP) 显示文摘Dirk Vanderschueren Naoki Yoshinaga and Kazuo Koyama 1996ISIJ International1996,36,8:1
19Thrombocytopenia and prognosis in intensive care显示文摘 de WEERDT A MALLBRAIN M 2000Crit Care Med2000,28,6:1
20Thrombocy-topenia and prognosis in intensive care显示文摘Vanderschueren S De Weerdt A Malbrain M 2000Crit Care Med2000,28,6:1
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