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| 1 | Role of perinatal long-chain omega-3 fatty acids in cortical circuit maturation:Mechanisms and implications for psychopathology显示文摘Accumulating translational evidence suggests that the long-chain omega-3 fatty acid docosahexaenoic acid(DHA) plays a role in the maturation and stability of cortical circuits that are impaired in different recurrent psychiatric disorders. Specifically, rodent and cell culture studies find that DHA preferentially accumulates in synaptic and growth cone membranes and promotes neurite outgrowth, dendritic spine stability, and synaptogenesis. Additional evidence suggests that DHA may play a role in microglia-mediated synaptic pruning, as well as myelin development and resilience. In nonhuman primates n-3 fatty acid insufficiency during perinatal development leads to widespread deficits in functional connectivity in adult frontal cortical networks compared to primates raised on DHA-fortified diet. Preterm delivery in non-human primates and humans is associated with early deficits in cortical DHA accrual. Human preterm birth is associated with longstanding deficits in myelin integrity and cortical circuit connectivity and increased risk for attention deficit/hyperactivity disorder(ADHD), mood, and psychotic disorders. In general, ADHD and mood and psychotic disorders initially emerge during rapid periods of cortical circuit maturation and are characterized by DHA deficits, myelin pathology, and impaired cortical circuit connectivity. Together these associations suggest that early and uncorrected deficits in fetal brain DHA accrual may represent a modifiable risk factor for cortical circuit maturation deficits in psychiatric disorders, and could therefore have significant implications for informing early intervention and prevention strategies. | Robert K McNamara Jennifer J Vannest Christina J Valentine | 2015 | World Journal of Psychiatry2015，5，1： | 2 |
| 2 | Tobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control study显示文摘 | Koon K Teo Stephanie Ounpuu Steven Hawken MR Pandey Vicent Valentin David Hunt Rafael Diaz Wafa Rashed Rosario Freeman Lixin Jiang Xiaofei Zhang Salim Yusuf | 2006 | The Lancet . 2006 (9536)2006，，9536： | 2 |
| 3 | Residents' Perceptions of Community Tourism Impacts 显示文摘 | ANDERECK K L VALENTINE K M KNOPF R C | 2005 | Annals of Tourism Research2005，32，4： | 1 |
| 4 | CFD Evaluation of Waterwall Wastage in Coal-fired Utility Boilers 显示文摘 | VALENTINE J R SHIM H-S DAVIS K A | 2007 | Energy & Fuels2007，21，： | 1 |
| 5 | Transvaginal doppler examination of uteri with myomas显示文摘 | Valentin L Marsal K | 1996 | J Clin Ultrasound1996，24，3： | 1 |
| 6 | Supercritical COs dried chitosan: an efficient intrinsic heterogeneous catalyst in fine chemistry 显示文摘 | Valentin R Molvinger K | 2003 | New J Chem2003，27，： | 1 |
| 7 | lipopmtein(a), homo- cysteine,and hypercoagulahle states in young men with prema- ture peripheral athemselerosis :a prospective controlled analysis 显示文摘 | Valentine RJ Kaplan HS Green K | 1966 | J VascSurg1966，23，1： | 1 |
| 8 | Carbon monoxide poisoning:risk factors for cognitive sequelae and the role of hyperbaric oxygen显示文摘 | Weaver L K Valentine K J Hopkins R O | | 0，，05： | 1 |
| 9 | AMPK activation: a therapeutic target for type 2 diabetes?显示文摘 | Coughlan K A Valentine R J Ruderman N B | 2014 | Diabetes Metab Syndr Obes2014，24，7： | 1 |
| 10 | Transcriptomic analysis of acclimation to temperatureand light stress in Saccharina latissima (Phaeophyceae)显示文摘 | Heinrich S Valentin K Frickenhaus S | 2012 | PLoS One2012，7，44： | 1 |
| 11 | Residents ' perceptions of community tourism impacts显示文摘 | Andereck K Valentine K Knopf R | 2005 | Anrtals of Tottrisrn Research2005，32，4： | 1 |
| 12 | Globin S-Propyl Cysteine and urinary N-Acetyl-S-propylcysteine as internal biomarkers of 1- bromopropane exposure显示文摘 | Valentine H Amamath K Ichihara G | 2007 | Toxieol Sci2007，98，2： | 1 |
| 13 | Limited contribution of Doppler velocimetry to the differential diagnosis of extrauterine pelvic tumors显示文摘 | Valentin L Sladkevicius P Marrsal K | 1994 | Obstet Gynecol1994，83，3： | 1 |
| 14 | Effects of molecular confinement on protein structure and stability显示文摘 | Eggers D K Valentine J S | 2001 | Abstracts of Papers of the American Chemical Society2001，221，： | 1 |
| 15 | Molecular confinement influences protein structure and enhances thermal proteinstability显示文摘 | Eggers D K Valentine J S | 2001 | Protein Science2001，10，2： | 1 |
| 16 | Metabolism of N-Butyl Benzyl Phthalate in the Female wistar Rat显示文摘 | Nativelle K Picard I Valentin J C | 1999 | Food and Chemical Toxicology1999，37，： | 1 |
| 17 | SWOT Analysis from a resource-based view显示文摘 | VALENTIN E K | 2001 | Journal of Marketing Theory and Practice2001，9，2： | 1 |
| 18 | Effects of nutrient enrichment and small predator density on sea- grass ecosystems: an experimental assessment显示文摘 | Heck K L Pennock J R Valentine J F | 2000 | Lim- nology and Oceanography2000，45，5： | 1 |
| 19 | Effects of exercise and low-fat diet on adipose tissue inflam- mation and metabohc c~mphcations in obese mice 显示文摘 | VIEIRA V J VALENTINE R J WILUND K R | 2009 | Am J Physiol Endocrinol Metab2009，296，5： | 1 |
| 20 | Pectus excavatum with inspiratory inferior vena cava compression:a new presentation of pulsus paradoxus显示文摘 | Yalamanchili K Summer W Valentine V | 2005 | Am J Med Sei2005，329，1： | 1 |
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